MX2009002987A - Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias. - Google Patents
Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias.Info
- Publication number
- MX2009002987A MX2009002987A MX2009002987A MX2009002987A MX2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A MX 2009002987 A MX2009002987 A MX 2009002987A
- Authority
- MX
- Mexico
- Prior art keywords
- eubacteria
- novel
- genetically programmed
- programmed expression
- sulfated proteins
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title 1
- 108091005994 sulfated proteins Proteins 0.000 title 1
- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 abstract 3
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 abstract 3
- 102000003960 Ligases Human genes 0.000 abstract 2
- 108090000364 Ligases Proteins 0.000 abstract 2
- CIQHWLTYGMYQQR-QMMMGPOBSA-N O(4')-sulfo-L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(OS(O)(=O)=O)C=C1 CIQHWLTYGMYQQR-QMMMGPOBSA-N 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 241001112695 Clostridiales Species 0.000 abstract 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84651906P | 2006-09-21 | 2006-09-21 | |
| US85521006P | 2006-10-28 | 2006-10-28 | |
| PCT/US2007/020459 WO2008036392A2 (en) | 2006-09-21 | 2007-09-20 | Genetically programmed expression of selectively sulfated proteins in eubacteria |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009002987A true MX2009002987A (es) | 2009-04-28 |
Family
ID=39201110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009002987A MX2009002987A (es) | 2006-09-21 | 2007-09-20 | Expresion geneticamente programada de proteinas selectivamente sulfatadas en eubacterias. |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US8114627B2 (https=) |
| EP (1) | EP2052083B1 (https=) |
| JP (1) | JP5385143B2 (https=) |
| KR (1) | KR20090074765A (https=) |
| CN (1) | CN101516901B (https=) |
| AU (1) | AU2007297610A1 (https=) |
| BR (1) | BRPI0716963A2 (https=) |
| CA (1) | CA2663052A1 (https=) |
| ES (1) | ES2456331T3 (https=) |
| IL (1) | IL197531A0 (https=) |
| MX (1) | MX2009002987A (https=) |
| PL (1) | PL2052083T3 (https=) |
| PT (1) | PT2052083E (https=) |
| RU (1) | RU2009110152A (https=) |
| WO (1) | WO2008036392A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002085923A2 (en) | 2001-04-19 | 2002-10-31 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| MXPA05003978A (es) * | 2002-10-16 | 2005-06-22 | Scripps Research Inst | Sintesis de glicoproteinas. |
| JP5642916B2 (ja) | 2003-04-17 | 2014-12-17 | ザ スクリプス リサーチ インスティテュート | 真核遺伝コードの拡張 |
| EP1649004A4 (en) | 2003-07-07 | 2008-04-09 | Scripps Research Inst | COMPOSITIONS WITH PAIRS OF ORTHOGONAL LYSYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF |
| JP5513398B2 (ja) * | 2007-11-02 | 2014-06-04 | ザ スクリプス リサーチ インスティチュート | 非天然アミノ酸を含有する蛋白質を使用する指向的進化 |
| US8658394B2 (en) * | 2011-02-02 | 2014-02-25 | Waterstone Pharmaceuticals | Methods, cells and systems for incorporating non-canonical amino acids into proteins |
| CN102888387B (zh) * | 2011-07-21 | 2015-03-18 | 中国科学院生物物理研究所 | 3-氯代酪氨酸翻译系统及其应用 |
| CN103571804B (zh) * | 2012-08-10 | 2015-08-12 | 中国科学院生物物理研究所 | 3-吡唑基酪氨酸翻译系统及其应用 |
| WO2015120287A2 (en) * | 2014-02-06 | 2015-08-13 | Yale University | Compositions and methods of use thereof for making polypeptides with many instances of nonstandard amino acids |
| US11408007B2 (en) | 2014-09-26 | 2022-08-09 | Yale University | Compositions and methods for biocontainment of microorganisms |
| CN110117580B (zh) * | 2018-02-05 | 2021-12-14 | 中国科学院生物物理研究所 | 硒代酪氨酸翻译系统及其应用 |
| IL280198B2 (en) * | 2018-07-18 | 2026-01-01 | Regenxbio Inc | Treatment of mucopolysaccharidosis I with fully glycosylated human iduronidase-alpha-L (idus) |
| US12371817B2 (en) * | 2019-03-04 | 2025-07-29 | The Texas A&M University System | Methods of making and utilizing amber-obligated phage display libraries |
| US11149280B2 (en) | 2019-10-29 | 2021-10-19 | Yale University | Engineering organisms resistant to viruses and horizontally transferred genetic elements |
| CN111304234A (zh) * | 2020-02-27 | 2020-06-19 | 江南大学 | 一种适用于枯草芽孢杆菌的非天然氨基酸利用工具 |
| CN113789335B (zh) * | 2021-11-16 | 2022-03-15 | 江苏省中国科学院植物研究所 | 一种水蛭酪氨酸磺酸转移酶基因及其应用 |
| CN118389493B (zh) * | 2024-05-10 | 2025-04-11 | 北京大学 | 一种定点修饰的工程化tRNA及其应用 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204016B1 (en) * | 1998-01-29 | 2001-03-20 | The Board Of Regents Of The University Of Oklahoma | Tyrosylprotein sulfotransferases and methods of use thereof |
| WO2002085923A2 (en) * | 2001-04-19 | 2002-10-31 | The Scripps Research Institute | In vivo incorporation of unnatural amino acids |
| MXPA05003978A (es) * | 2002-10-16 | 2005-06-22 | Scripps Research Inst | Sintesis de glicoproteinas. |
| JP4444113B2 (ja) * | 2002-10-16 | 2010-03-31 | ザ スクリップス リサーチ インスティテュート | ケトアミノ酸の部位特異的蛋白質組込み方法 |
| CA2508939A1 (en) * | 2002-12-22 | 2004-07-15 | The Scripps Research Institute | Protein arrays |
| JP5642916B2 (ja) * | 2003-04-17 | 2014-12-17 | ザ スクリプス リサーチ インスティテュート | 真核遺伝コードの拡張 |
| EP2410331B1 (en) * | 2003-06-18 | 2015-09-23 | The Scripps Research Institute | Aminoacyl-tRNA synthetase for aminoacylation tRNA with unnatural amino acids |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
| EP1649004A4 (en) | 2003-07-07 | 2008-04-09 | Scripps Research Inst | COMPOSITIONS WITH PAIRS OF ORTHOGONAL LYSYL-TRNA AND AMINOACYL-TRNA-SYNTHETASE AND USES THEREOF |
| US20060160175A1 (en) * | 2003-07-07 | 2006-07-20 | The Scripps Research Institute | Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| PT1687401E (pt) | 2003-10-14 | 2013-02-26 | Scripps Research Inst | Incorporação de aminoácidos activos em oxidação-redução específica do local em proteínas |
| US7741071B2 (en) * | 2003-12-18 | 2010-06-22 | The Scripps Research Institute | Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells |
| JP2008500050A (ja) | 2004-05-25 | 2008-01-10 | ザ スクリップス リサーチ インスティテュート | 結晶構造決定のための重原子含有非天然アミノ酸の部位特異的蛋白質組込み |
| AU2005286722B2 (en) | 2004-09-21 | 2010-12-02 | The Scripps Research Institute | In vivo incorporation of alkynyl amino acids into proteins in eubacteria |
| US20090181858A1 (en) * | 2004-09-21 | 2009-07-16 | The Scripps Research Institute | Adding photoregulated amino acids to the genetic code |
| US20080171317A1 (en) | 2004-09-22 | 2008-07-17 | The Scripps Research Institute | Site-Specific Labeling of Proteins for Nmr Studies |
| JP2008516637A (ja) * | 2004-10-20 | 2008-05-22 | ザ スクリップス リサーチ インスティテュート | 真正細菌へのｎ−アセチルガラクトサミンアミノ酸のインビボ部位特異的組込み |
| CN101048506B (zh) | 2004-10-27 | 2013-06-26 | 斯克利普斯研究院 | 体内掺入非天然氨基酸的正交翻译组分 |
| BRPI0617191A2 (pt) * | 2005-10-12 | 2011-07-19 | Scripps Research Inst | modificação pós-traducional de polipeptìdeos expressos em fagos |
| KR20080106430A (ko) | 2006-03-09 | 2008-12-05 | 더 스크립스 리서치 인스티튜트 | 진정 세균 숙주 세포 내에서의 직교형 번역 성분의 발현을 위한 시스템 |
| WO2007109035A2 (en) | 2006-03-16 | 2007-09-27 | The Scripps Research Institute | Genetically programmed expression of proteins containing the unnatural amino acid phenylselenocysteine |
-
2007
- 2007-09-20 JP JP2009529249A patent/JP5385143B2/ja not_active Expired - Fee Related
- 2007-09-20 RU RU2009110152/10A patent/RU2009110152A/ru not_active Application Discontinuation
- 2007-09-20 EP EP07861356.9A patent/EP2052083B1/en not_active Not-in-force
- 2007-09-20 WO PCT/US2007/020459 patent/WO2008036392A2/en not_active Ceased
- 2007-09-20 US US11/903,499 patent/US8114627B2/en active Active
- 2007-09-20 BR BRPI0716963-9A patent/BRPI0716963A2/pt not_active IP Right Cessation
- 2007-09-20 AU AU2007297610A patent/AU2007297610A1/en not_active Abandoned
- 2007-09-20 CA CA002663052A patent/CA2663052A1/en not_active Abandoned
- 2007-09-20 MX MX2009002987A patent/MX2009002987A/es not_active Application Discontinuation
- 2007-09-20 US US12/311,169 patent/US8114652B2/en active Active
- 2007-09-20 KR KR1020097007574A patent/KR20090074765A/ko not_active Ceased
- 2007-09-20 PT PT78613569T patent/PT2052083E/pt unknown
- 2007-09-20 CN CN200780035189.6A patent/CN101516901B/zh not_active Expired - Fee Related
- 2007-09-20 PL PL07861356T patent/PL2052083T3/pl unknown
- 2007-09-20 ES ES07861356.9T patent/ES2456331T3/es active Active
-
2009
- 2009-03-11 IL IL197531A patent/IL197531A0/en unknown
-
2011
- 2011-12-14 US US13/326,143 patent/US8361770B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20090286279A1 (en) | 2009-11-19 |
| JP2010504096A (ja) | 2010-02-12 |
| JP5385143B2 (ja) | 2014-01-08 |
| WO2008036392A3 (en) | 2008-12-31 |
| CA2663052A1 (en) | 2008-03-27 |
| EP2052083A2 (en) | 2009-04-29 |
| IL197531A0 (en) | 2009-12-24 |
| PL2052083T3 (pl) | 2014-06-30 |
| EP2052083A4 (en) | 2010-03-24 |
| CN101516901A (zh) | 2009-08-26 |
| US20120184018A1 (en) | 2012-07-19 |
| KR20090074765A (ko) | 2009-07-07 |
| CN101516901B (zh) | 2014-01-08 |
| BRPI0716963A2 (pt) | 2013-11-05 |
| AU2007297610A1 (en) | 2008-03-27 |
| EP2052083B1 (en) | 2014-01-08 |
| PT2052083E (pt) | 2014-04-10 |
| RU2009110152A (ru) | 2010-10-27 |
| US8361770B2 (en) | 2013-01-29 |
| WO2008036392A9 (en) | 2008-05-22 |
| US20080113407A1 (en) | 2008-05-15 |
| US8114652B2 (en) | 2012-02-14 |
| US8114627B2 (en) | 2012-02-14 |
| WO2008036392A2 (en) | 2008-03-27 |
| ES2456331T3 (es) | 2014-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |