MX2008010920A - Prueba de anticuerpo anti-farmaco. - Google Patents

Prueba de anticuerpo anti-farmaco.

Info

Publication number
MX2008010920A
MX2008010920A MX2008010920A MX2008010920A MX2008010920A MX 2008010920 A MX2008010920 A MX 2008010920A MX 2008010920 A MX2008010920 A MX 2008010920A MX 2008010920 A MX2008010920 A MX 2008010920A MX 2008010920 A MX2008010920 A MX 2008010920A
Authority
MX
Mexico
Prior art keywords
drug antibody
antibody
drug
antibody assay
mixture
Prior art date
Application number
MX2008010920A
Other languages
English (en)
Inventor
Kay-Gunnar Stubenrauch
Wolfgang Hoesel
Rudolf Vogel
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2008010920A publication Critical patent/MX2008010920A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format

Abstract

La invención proporciona un método para la determinación inmunológica de un anticuerpo contra un anticuerpo de fármaco en una muestra usando un inmunoanálisis de puente de antígeno doble que comprende un anticuerpo de fármaco de captura y un anticuerpo del fármaco trazador, caracterizado porque el anticuerpo de fármaco de captura es una mezcla del anticuerpo del fármaco conjugado a la fase sólida en por lo menos dos sitios de anticuerpo diferentes y el anticuerpo de fármaco trazador es una mezcla del anticuerpo de fármaco conjugado a la marca detectable en por lo menos dos sitios de anticuerpo diferentes.
MX2008010920A 2006-03-09 2007-03-07 Prueba de anticuerpo anti-farmaco. MX2008010920A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06004806 2006-03-09
PCT/EP2007/001935 WO2007101661A1 (en) 2006-03-09 2007-03-07 Anti-drug antibody assay

Publications (1)

Publication Number Publication Date
MX2008010920A true MX2008010920A (es) 2008-09-03

Family

ID=36608542

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008010920A MX2008010920A (es) 2006-03-09 2007-03-07 Prueba de anticuerpo anti-farmaco.

Country Status (12)

Country Link
US (4) US20090061466A1 (es)
EP (1) EP1996943B1 (es)
JP (2) JP4902674B2 (es)
KR (1) KR101047207B1 (es)
CN (1) CN101371140B (es)
AU (1) AU2007222584B2 (es)
BR (1) BRPI0708677A2 (es)
CA (1) CA2644529C (es)
ES (1) ES2498377T3 (es)
IL (1) IL192604A (es)
MX (1) MX2008010920A (es)
WO (1) WO2007101661A1 (es)

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GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
CN103399145B (zh) * 2007-12-15 2015-06-24 霍夫曼-拉罗奇有限公司 区分测定
AU2013202747B2 (en) * 2007-12-15 2014-02-13 F. Hoffmann-La Roche Ag Distinguishing assay
PE20091174A1 (es) 2007-12-27 2009-08-03 Chugai Pharmaceutical Co Ltd Formulacion liquida con contenido de alta concentracion de anticuerpo
WO2010042031A1 (en) * 2008-10-07 2010-04-15 Gyros Patent Ab Semi-sequential assay for detection of an analyte in a sample
US8614297B2 (en) 2008-12-22 2013-12-24 Hoffmann-La Roche Inc. Anti-idiotype antibody against an antibody against the amyloid β peptide
JP2012533064A (ja) * 2009-07-08 2012-12-20 エイエヌピー テクノロジーズ， インコーポレイテッド 免疫原性アッセイ
BR112012009828B8 (pt) 2009-10-26 2022-10-25 Hoffmann La Roche Método para a produção de uma imunoglobulina glicosilada e seu uso
EP2354792A1 (en) * 2010-02-08 2011-08-10 Biomonitor A/S Method for detecting anti-drug antibodies
HUE027662T2 (en) * 2010-04-29 2016-10-28 Theradiag Sa Procedures for Determining Antibodies to Medicine
BR112013009376A2 (pt) * 2010-10-18 2016-07-26 Nestec Sa métodos para determinar isótipos de anticorpos antifármacos
MX2013005024A (es) 2010-11-08 2013-11-21 Chugai Pharmaceutical Co Ltd Anticuerpo anti-il-6 receptor administrado subcutaneamente.
JP6563910B2 (ja) 2013-07-04 2019-08-21 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ
DK3105592T3 (en) 2014-02-11 2019-02-04 Genzyme Corp PROCEDURES FOR DETERMINING THE PRESENCE OR THE QUANTITY OF AN ANTI-MEDICINE ANTIBODY
EP2982987A1 (en) * 2014-08-08 2016-02-10 Proteomika, S.L. Lateral flow immunoassays for the detection of antibodies against biological drugs
EP3391050B1 (en) * 2015-12-16 2020-09-16 F. Hoffmann-La Roche AG Three-step acid dissociation enzyme linked immunosorbent (tadelis) assay
CN109358192B (zh) * 2018-02-08 2020-05-12 中国科学院上海药物研究所 一种去除抗药抗体检测样品中游离药物的装置和方法、该装置的制备方法及应用
GB201905100D0 (en) 2019-04-10 2019-05-22 Antibody Innovation Ltd Polypeptides and methods of use
WO2021046316A2 (en) * 2019-09-05 2021-03-11 Adverum Biotechnologies Anti-drug antibody assay
US20230158458A1 (en) 2020-04-23 2023-05-25 S. A. Lhoist Recherche Et Developpement Calcium and/or Magnesium Additive for Membrane and Fouling Control and System and Process for Membrane Fouling Control Using the Additive
US20230158456A1 (en) 2020-04-23 2023-05-25 S. A. Lhoist Recherche Et Developpement System and Process for Membrane Fouling Control, A Membrane Fouling Control Additive, an Upgrade Kit and an Upgrade Method
JP7062803B1 (ja) 2021-03-31 2022-05-06 積水メディカル株式会社 抗薬物抗体測定方法
WO2023110918A1 (en) 2021-12-14 2023-06-22 Cdr-Life Ag Dual mhc-targeting t cell engager
US20240091262A1 (en) 2022-09-14 2024-03-21 Cdr-Life Ag Mage-a4 peptide dual t cell engagers

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Also Published As

Publication number Publication date
AU2007222584B2 (en) 2012-07-12
JP2009529662A (ja) 2009-08-20
EP1996943B1 (en) 2014-06-25
EP1996943A1 (en) 2008-12-03
US20150253338A1 (en) 2015-09-10
CN101371140B (zh) 2013-11-13
JP2012073266A (ja) 2012-04-12
CA2644529A1 (en) 2007-09-13
KR101047207B1 (ko) 2011-07-06
WO2007101661A1 (en) 2007-09-13
US20090061466A1 (en) 2009-03-05
ES2498377T3 (es) 2014-09-24
CA2644529C (en) 2014-05-06
IL192604A0 (en) 2009-02-11
AU2007222584A1 (en) 2007-09-13
IL192604A (en) 2010-12-30
US20230111088A1 (en) 2023-04-13
CN101371140A (zh) 2009-02-18
KR20080102164A (ko) 2008-11-24
BRPI0708677A2 (pt) 2011-06-21
JP4902674B2 (ja) 2012-03-21
US20190170765A1 (en) 2019-06-06

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