MX2007005083A - Oligonucleotidos antisentido para tratar alergias y proliferacion celular neoplastica. - Google Patents
Oligonucleotidos antisentido para tratar alergias y proliferacion celular neoplastica.Info
- Publication number
- MX2007005083A MX2007005083A MX2007005083A MX2007005083A MX2007005083A MX 2007005083 A MX2007005083 A MX 2007005083A MX 2007005083 A MX2007005083 A MX 2007005083A MX 2007005083 A MX2007005083 A MX 2007005083A MX 2007005083 A MX2007005083 A MX 2007005083A
- Authority
- MX
- Mexico
- Prior art keywords
- oligonucleotide
- seq
- antisense oligonucleotide
- pharmaceutical composition
- antisense
- Prior art date
Links
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
- C12N2310/331—Universal or degenerate base
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62320604P | 2004-10-29 | 2004-10-29 | |
| PCT/CA2005/001656 WO2006045202A1 (en) | 2004-10-29 | 2005-10-27 | Antisense oligonucleotides for treating allergy and neoplastic cell proliferation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007005083A true MX2007005083A (es) | 2007-10-03 |
Family
ID=36226992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007005083A MX2007005083A (es) | 2004-10-29 | 2005-10-27 | Oligonucleotidos antisentido para tratar alergias y proliferacion celular neoplastica. |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8119790B2 (enExample) |
| EP (1) | EP1812075B1 (enExample) |
| JP (1) | JP5314283B2 (enExample) |
| CN (1) | CN101087623B (enExample) |
| AU (1) | AU2005299218B2 (enExample) |
| BR (1) | BRPI0517387A8 (enExample) |
| CA (1) | CA2584457C (enExample) |
| ES (1) | ES2450929T3 (enExample) |
| MX (1) | MX2007005083A (enExample) |
| NZ (1) | NZ554723A (enExample) |
| RU (1) | RU2416412C2 (enExample) |
| WO (1) | WO2006045202A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2285961A4 (en) | 2008-05-15 | 2012-10-17 | Topigen Pharmaceuticals Inc | OLIGONUCLEOTIDES FOR THE TREATMENT OF INFLAMMATION AND NEOPLASTIC CELL REPRODUCTION |
| ES2625689T3 (es) | 2010-04-29 | 2017-07-20 | Ionis Pharmaceuticals, Inc. | Modulación de la expresión de transtiretina |
| JP2014511181A (ja) * | 2011-02-24 | 2014-05-15 | ファーマキシス リミテッド | キメラ骨格および２−アミノ−２’−デオキシアデノシンを有するオリゴヌクレオチド阻害剤 |
| US9901079B2 (en) | 2011-08-18 | 2018-02-27 | New York University | Inhibition of oncogenic kras-induced GM-CSF production and function |
| WO2015066262A1 (en) * | 2013-11-04 | 2015-05-07 | Trustees Of Dartmouth College | Methods for preventing toxicity of adoptive cell therapy |
| HK1255922A1 (zh) | 2015-11-04 | 2019-09-06 | Astrazeneca Ab | 二肽基肽酶-4和骨膜素作为嗜酸性粒细胞疾病中嗜酸性粒细胞靶向治疗药物临床反应的预测因子 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3337530A (en) | 1965-09-20 | 1967-08-22 | Upjohn Co | Dinucleoside 3', 5' -and 2', 5'-phosphates containing one 7-deazapurin riboside moiety |
| US4880635B1 (en) | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| US4921757A (en) | 1985-04-26 | 1990-05-01 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
| US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
| JPH0825869B2 (ja) | 1987-02-09 | 1996-03-13 | 株式会社ビタミン研究所 | 抗腫瘍剤包埋リポソ−ム製剤 |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| US4917951A (en) | 1987-07-28 | 1990-04-17 | Micro-Pak, Inc. | Lipid vesicles formed of surfactants and steroids |
| US5646265A (en) | 1990-01-11 | 1997-07-08 | Isis Pharmceuticals, Inc. | Process for the preparation of 2'-O-alkyl purine phosphoramidites |
| US5872242A (en) | 1992-10-05 | 1999-02-16 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide inhibition of ras |
| GB9301000D0 (en) | 1993-01-20 | 1993-03-10 | Glaxo Group Ltd | Chemical compounds |
| US6806061B1 (en) * | 1995-01-19 | 2004-10-19 | Children's Medical Center Corporation | G protein-coupled receptor gene and methods of use therefor |
| US5874211A (en) | 1995-04-13 | 1999-02-23 | Incyte Pharmaceuticals, Inc. | Chemokine expressed in eosinophils |
| FR2734147B1 (fr) | 1995-05-19 | 1997-10-10 | Klein Jean Michel | Dispositif d'osteosynthese implantable |
| US6825174B2 (en) | 1995-06-07 | 2004-11-30 | East Carolina University | Composition, formulations & method for prevention & treatment of diseases and conditions associated with bronchoconstriction, allergy(ies) & inflammation |
| US6025339A (en) | 1995-06-07 | 2000-02-15 | East Carolina University | Composition, kit and method for treatment of disorders associated with bronchoconstriction and lung inflammation |
| FR2742156A1 (fr) | 1995-12-06 | 1997-06-13 | Sanofi Sa | Polypeptide recepteur de l'il-13 |
| US6265184B1 (en) | 1995-12-20 | 2001-07-24 | Icos Corporation | Polynucleotides encoding chemokine receptor 88C |
| WO1997023244A1 (en) | 1995-12-22 | 1997-07-03 | Smithkline Beecham Corporation | Use of antisene oligodeoxynucleotides to produce truncated proteins |
| AUPN780096A0 (en) | 1996-01-30 | 1996-02-22 | Medvet Science Pty. Ltd. | Cytokine antagonists and agonists |
| EP1012190A4 (en) | 1996-04-26 | 2004-04-28 | Merck & Co Inc | Eotaxin receptor from eosinophils |
| JP2000510690A (ja) | 1996-04-26 | 2000-08-22 | インサイト・ファーマスーティカルズ・インコーポレイテッド | 哺乳類混合リンパ球受容体、ケモカイン受容体（ｍｍｌｒ―ｃｃｒ） |
| US5807708A (en) | 1996-07-30 | 1998-09-15 | Millennium Pharmaceuticals, Inc. | Conservin nucleic acid molecules and compositions |
| EP1019065A4 (en) | 1997-09-17 | 2002-02-20 | Univ East Carolina | NUCLEIC ACIDS HYBRIDIZING TO MULTIPLE TARGETS, THEIR PREPARATION, COMPOSITIONS, FORMULATION, KITS AND APPLICATIONS |
| CA2235420A1 (en) * | 1998-06-17 | 1999-12-17 | Paolo Renzi | Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation |
| ATE346918T1 (de) | 1998-06-19 | 2006-12-15 | Univ Mcgill | Auf beta-arabinose, und dessen analogen, basierte antisense oligonukleotide |
| HK1042706A1 (zh) | 1998-08-03 | 2002-08-23 | 东卡罗来纳大学 | 低腺苷反义寡核苷酸制剂、组合物、试剂盒及处理 |
| US6175004B1 (en) | 1998-09-01 | 2001-01-16 | Isis Pharmaceuticals, Inc. | Process for the synthesis of oligonucleotides incorporating 2-aminoadenosine |
| AU4031700A (en) | 1999-04-06 | 2000-11-02 | East Carolina University | Low adenosine anti-sense oligonucleotide, compositions, kit and method for treatment of airway disorders associated with bronchoconstriction, lung inflammation,allergy(ies) and surfactant depletion |
| CA2419563C (en) | 2000-09-06 | 2018-03-20 | Mcgill University | Chimeric antisense of arabinofuranose analogue and deoxyribose nucleotides |
| US20020151064A1 (en) * | 2001-02-07 | 2002-10-17 | Children's Hospital Medical Center | Regulation of CCR3 expression |
| PT1406667E (pt) | 2001-07-06 | 2008-05-23 | Topigen Pharmaceuticals Inc | Métodos para aumentar a eficácia in vivo de oligonucleótidos e a inibição da inflamação em mamíferos |
| JP2005508634A (ja) | 2001-10-29 | 2005-04-07 | マクギル・ユニヴァーシティ | 非環式リンカー含有オリゴヌクレオチド及びその用途 |
| DK1470144T3 (da) | 2002-02-01 | 2009-04-06 | Univ Mcgill | Oligonukleotider omfattende alternerende segmenter og anvendelser deraf |
-
2005
- 2005-10-27 MX MX2007005083A patent/MX2007005083A/es active IP Right Grant
- 2005-10-27 EP EP05802169.2A patent/EP1812075B1/en not_active Expired - Lifetime
- 2005-10-27 AU AU2005299218A patent/AU2005299218B2/en not_active Ceased
- 2005-10-27 RU RU2007119777/15A patent/RU2416412C2/ru not_active IP Right Cessation
- 2005-10-27 US US11/666,647 patent/US8119790B2/en not_active Expired - Fee Related
- 2005-10-27 NZ NZ554723A patent/NZ554723A/en not_active IP Right Cessation
- 2005-10-27 CN CN2005800448619A patent/CN101087623B/zh not_active Expired - Fee Related
- 2005-10-27 JP JP2007538227A patent/JP5314283B2/ja not_active Expired - Fee Related
- 2005-10-27 WO PCT/CA2005/001656 patent/WO2006045202A1/en not_active Ceased
- 2005-10-27 CA CA2584457A patent/CA2584457C/en not_active Expired - Fee Related
- 2005-10-27 ES ES05802169.2T patent/ES2450929T3/es not_active Expired - Lifetime
- 2005-10-27 BR BRPI0517387A patent/BRPI0517387A8/pt not_active Application Discontinuation
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2011
- 2011-11-21 US US13/301,183 patent/US8202851B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101087623A (zh) | 2007-12-12 |
| AU2005299218B2 (en) | 2012-04-12 |
| EP1812075A4 (en) | 2010-04-07 |
| AU2005299218A2 (en) | 2008-10-30 |
| RU2007119777A (ru) | 2008-12-10 |
| US8119790B2 (en) | 2012-02-21 |
| BRPI0517387A (pt) | 2008-10-07 |
| AU2005299218A1 (en) | 2006-05-04 |
| ES2450929T3 (es) | 2014-03-25 |
| CA2584457C (en) | 2012-10-23 |
| WO2006045202A1 (en) | 2006-05-04 |
| NZ554723A (en) | 2009-12-24 |
| EP1812075B1 (en) | 2013-12-11 |
| US8202851B2 (en) | 2012-06-19 |
| CA2584457A1 (en) | 2006-05-04 |
| US20090215861A1 (en) | 2009-08-27 |
| EP1812075A1 (en) | 2007-08-01 |
| RU2416412C2 (ru) | 2011-04-20 |
| BRPI0517387A8 (pt) | 2017-07-11 |
| JP2008517953A (ja) | 2008-05-29 |
| JP5314283B2 (ja) | 2013-10-16 |
| CN101087623B (zh) | 2012-09-26 |
| US20120065249A1 (en) | 2012-03-15 |
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