EP1012190A4 - Eosinophil eotaxin receptor - Google Patents

Eosinophil eotaxin receptor

Info

Publication number
EP1012190A4
EP1012190A4 EP97925399A EP97925399A EP1012190A4 EP 1012190 A4 EP1012190 A4 EP 1012190A4 EP 97925399 A EP97925399 A EP 97925399A EP 97925399 A EP97925399 A EP 97925399A EP 1012190 A4 EP1012190 A4 EP 1012190A4
Authority
EP
European Patent Office
Prior art keywords
eotaxin receptor
eosinophil eotaxin
eosinophil
receptor
eotaxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP97925399A
Other languages
German (de)
French (fr)
Other versions
EP1012190A1 (en
Inventor
Bruce L Daugherty
Julie A Demartino
Martin S Springer
Salvatore J Siciliano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700894.0A external-priority patent/GB9700894D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of EP1012190A1 publication Critical patent/EP1012190A1/en
Publication of EP1012190A4 publication Critical patent/EP1012190A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP97925399A 1996-04-26 1997-04-24 Eosinophil eotaxin receptor Withdrawn EP1012190A4 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US1615896P 1996-04-26 1996-04-26
US1711396P 1996-04-26 1996-04-26
US17113P 1996-04-26
US16158P 1996-04-26
GBGB9700894.0A GB9700894D0 (en) 1997-01-17 1997-01-17 Eosinophil eotain receptor
GB9700894 1997-01-17
PCT/US1997/006568 WO1997041154A1 (en) 1996-04-26 1997-04-24 Eosinophil eotaxin receptor

Publications (2)

Publication Number Publication Date
EP1012190A1 EP1012190A1 (en) 2000-06-28
EP1012190A4 true EP1012190A4 (en) 2004-04-28

Family

ID=27268678

Family Applications (1)

Application Number Title Priority Date Filing Date
EP97925399A Withdrawn EP1012190A4 (en) 1996-04-26 1997-04-24 Eosinophil eotaxin receptor

Country Status (4)

Country Link
EP (1) EP1012190A4 (en)
JP (1) JP3689118B2 (en)
CA (1) CA2252850A1 (en)
WO (1) WO1997041154A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6537764B1 (en) 1995-01-19 2003-03-25 Children's Medical Center Corporation Method of identifying inhibitors of C—C chemokine receptor 3
JP2001527410A (en) * 1997-05-07 2001-12-25 シェーリング コーポレイション Methods for eosinophil depletion and compositions therefor
US6207155B1 (en) 1997-05-07 2001-03-27 Schering Corporation Method of eosinophil depletion with antibody to CCR 3 receptor
CA2235420A1 (en) 1998-06-17 1999-12-17 Paolo Renzi Antisense oligonucleotides for treating or preventing atopic diseases and neoplastic cell proliferation
US6358697B2 (en) 1999-04-21 2002-03-19 Children's Hospital Medical Center Intracellular pharmaceutical targeting
NZ531069A (en) * 2001-08-10 2007-01-26 Topigen Pharma Inc Methods for modulating viral infection of cells by modulating a binding interaction between a CCR1, CCR2, CCR3, CCR4, CCR5 and/or CCR8 receptor and a surface protein of the virus
ES2450929T3 (en) 2004-10-29 2014-03-25 Topigen Pharmaceuticals Inc. Antisense oligonucleotides to treat allergy and proliferation of neoplastic cells
AU2009246000B2 (en) * 2008-05-15 2014-09-04 Topigen Pharmaceuticals Inc. Oligonucleotides for treating inflammation and neoplastic cell proliferation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022371A2 (en) * 1995-01-19 1996-07-25 Leukosite, Inc. C-C CHEMOKINE RECEPTOR 3: CKP-3 OR Eos-L2
WO1997000960A1 (en) * 1995-06-23 1997-01-09 Leukosite, Inc. Novel human chemotactic cytokine
WO1997022698A2 (en) * 1995-12-20 1997-06-26 Icos Corporation Chemokine receptors 88-2b[ckr-3] and 88c and their antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401629A (en) * 1990-08-07 1995-03-28 The Salk Institute Biotechnology/Industrial Associates, Inc. Assay methods and compositions useful for measuring the transduction of an intracellular signal

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996022371A2 (en) * 1995-01-19 1996-07-25 Leukosite, Inc. C-C CHEMOKINE RECEPTOR 3: CKP-3 OR Eos-L2
WO1997000960A1 (en) * 1995-06-23 1997-01-09 Leukosite, Inc. Novel human chemotactic cytokine
WO1997022698A2 (en) * 1995-12-20 1997-06-26 Icos Corporation Chemokine receptors 88-2b[ckr-3] and 88c and their antibodies

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COMBADIERE C ET AL: "CLONING AND FUNCTIONAL EXPRESSION OF A HUMAN EOSINOPHIL CC CHEMOKINE RECEPTOR", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 270, no. 27, 14 July 1995 (1995-07-14), pages 16491 - 16494, XP001018021, ISSN: 0021-9258 *
KITAURA M ET AL: "MOLECULAR CLONING OF HUMAN EOTAXIN, AND EOSINOPHIL-SELECTIVE CC CHEMOKINE, AND IDENTIFICATION OF A SPECIFIC EOSINOPHIL EOTAXIN RECEPTOR, CC CHEMOKINE RECEPTOR 3", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 271, no. 13, 29 March 1996 (1996-03-29), pages 7725 - 7730, XP002944825, ISSN: 0021-9258 *
See also references of WO9741154A1 *

Also Published As

Publication number Publication date
JP3689118B2 (en) 2005-08-31
JP2002503950A (en) 2002-02-05
CA2252850A1 (en) 1997-11-06
WO1997041154A1 (en) 1997-11-06
EP1012190A1 (en) 2000-06-28

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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