MX167175B - Sistema de entrega de drogas, con liberacion controlada, para la bolsa periodontal - Google Patents

Sistema de entrega de drogas, con liberacion controlada, para la bolsa periodontal

Info

Publication number
MX167175B
MX167175B MX006257A MX625787A MX167175B MX 167175 B MX167175 B MX 167175B MX 006257 A MX006257 A MX 006257A MX 625787 A MX625787 A MX 625787A MX 167175 B MX167175 B MX 167175B
Authority
MX
Mexico
Prior art keywords
delivery system
drug delivery
controlled release
drug
periodontal bag
Prior art date
Application number
MX006257A
Other languages
English (en)
Inventor
Richard W Baker
Original Assignee
Pharametrix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25324860&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX167175(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharametrix Corp filed Critical Pharametrix Corp
Publication of MX167175B publication Critical patent/MX167175B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/15Compositions characterised by their physical properties
    • A61K6/17Particle size
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/30Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00Preparations for dentistry
    • A61K6/60Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)

Abstract

La presente invención se refiere a un sistema de entrega de drogas, con liberación controlada, para su colocación dentro de la bolsa periodontal, caracterizado porque comprende: (a) una pluralidad de micropartículas discretas, que constan de un polímero que contiene la droga y esta droga dispersa en el mismo y (b) un medio que suspende fluido para dichas micropartículas; el sistema de entrega de drogas permanece activo dentro de la bolsa periodontal por un período de tiempo entre 1 y 30 días.
MX006257A 1986-04-29 1987-04-28 Sistema de entrega de drogas, con liberacion controlada, para la bolsa periodontal MX167175B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/856,961 US4780320A (en) 1986-04-29 1986-04-29 Controlled release drug delivery system for the periodontal pocket

Publications (1)

Publication Number Publication Date
MX167175B true MX167175B (es) 1993-03-08

Family

ID=25324860

Family Applications (1)

Application Number Title Priority Date Filing Date
MX006257A MX167175B (es) 1986-04-29 1987-04-28 Sistema de entrega de drogas, con liberacion controlada, para la bolsa periodontal

Country Status (10)

Country Link
US (1) US4780320A (es)
EP (1) EP0244118B1 (es)
JP (1) JP2698353B2 (es)
AU (1) AU614061B2 (es)
CA (1) CA1309345C (es)
DE (1) DE3787829T2 (es)
DK (1) DK219287A (es)
MX (1) MX167175B (es)
NO (1) NO177125C (es)
NZ (1) NZ219948A (es)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
US5500228A (en) * 1987-05-26 1996-03-19 American Cyanamid Company Phase separation-microencapsulated pharmaceuticals compositions useful for alleviating dental disease
US5013553A (en) * 1987-06-30 1991-05-07 Vipont Pharmaceutical, Inc. Drug delivery devices
US5175000A (en) * 1987-06-30 1992-12-29 Vipont Pharmaceutical, Inc. Free amine benzophenanthridine alkaloid compositions
US4843099A (en) * 1987-07-20 1989-06-27 Colgate-Palmolive Company Device and composition for treatment of the gums
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5632727A (en) * 1988-10-03 1997-05-27 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
US5324520A (en) * 1988-12-19 1994-06-28 Vipont Pharmaceutical, Inc. Intragingival delivery systems for treatment of periodontal disease
ES2059683T3 (es) * 1988-12-22 1994-11-16 American Cyanamid Co Composiciones farmaceuticas microencapsuladas con separacion de fases, perfeccionadas, utiles para aliviar enfermedades dentales.
EP0374531B1 (en) * 1988-12-22 1994-05-04 American Cyanamid Company Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof
US5236355A (en) * 1988-12-22 1993-08-17 American Cyanamid Company Apparatus for the treatment of periodontal disease
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US5077049A (en) * 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
US5143934A (en) * 1990-11-21 1992-09-01 A/S Dumex (Dumex Ltd.) Method and composition for controlled delivery of biologically active agents
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US4997830A (en) * 1990-02-07 1991-03-05 The Research Foundation Of State University Of New York Pharmaceutical composition for the treatment of periodontitis
US5464609A (en) * 1990-03-16 1995-11-07 The Procter & Gamble Company Use of ketorolac for treatment of oral diseases and conditions
AU629316B2 (en) * 1990-04-11 1992-10-01 Flora Inc. Periodontal disease treatment system
USRE37950E1 (en) 1990-04-24 2002-12-31 Atrix Laboratories Biogradable in-situ forming implants and methods of producing the same
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
US5197882A (en) * 1990-05-14 1993-03-30 Gary R. Jernberg Periodontal barrier and method for aiding periodontal tissue regeneration agents
EP0489743A1 (en) * 1990-07-03 1992-06-17 Vipont Pharmaceutical, Inc. Intragingival delivery systems for treatment of periodontal disease
PT99345A (pt) * 1990-10-30 1992-09-30 Alza Corp Processo para a preparacao de sistemas apropriados para a libertacao de agentes terapeuticos
US5620700A (en) * 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
US5770588A (en) * 1991-02-11 1998-06-23 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions of the prevention and treatment of root caries
US5906834A (en) * 1992-06-15 1999-05-25 The Gillette Company Color changing matrix as wear indicator
US5340581A (en) * 1991-08-23 1994-08-23 Gillette Canada, Inc. Sustained-release matrices for dental application
ES2124739T3 (es) * 1991-08-23 1999-02-16 Gillette Co Matrices de liberacion sostenida de uso dental.
WO1993005680A1 (en) * 1991-09-13 1993-04-01 Gillette Canada Inc. Polymeric particles for dental applications
US5250288A (en) * 1991-09-13 1993-10-05 Gillette Canada, Inc. Method for desensitizing teeth
US5211939A (en) * 1991-09-13 1993-05-18 Gillette Canada Method for desensitizing teeth
AU704007B2 (en) * 1991-09-13 1999-04-01 Gillette Canada Inc. Toothbrushes
US5364634A (en) * 1991-11-08 1994-11-15 Southwest Research Institute Controlled-release PH sensitive capsule and adhesive system and method
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
EP0560014A1 (en) * 1992-03-12 1993-09-15 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
MX9301823A (es) * 1992-03-30 1994-01-31 Alza Corp Composicion para el suministro de liberacion controlado de un agente biologicamente activo.
AU3941793A (en) * 1992-03-30 1993-11-08 Alza Corporation Additives for bioerodible polymers to regulate degradation
ES2170074T3 (es) * 1992-09-10 2002-08-01 Childrens Medical Center Matrices de polimero biodegradables para la liberacion prolongada de agentes anestesicos locales.
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5242910A (en) * 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5447725A (en) * 1993-06-11 1995-09-05 The Procter & Gamble Company Methods for aiding periodontal tissue regeneration
WO1995001767A1 (en) * 1993-07-08 1995-01-19 Cygnus Therapeutic Systems Monolithic matrix transdermal delivery system
WO1995022308A1 (en) * 1994-02-17 1995-08-24 The Oralife Group, Inc. Method for the diagnosis and reduction of dental caries
US5502092A (en) * 1994-02-18 1996-03-26 Minnesota Mining And Manufacturing Company Biocompatible porous matrix of bioabsorbable material
CA2187355C (en) * 1994-04-08 2009-10-13 Richard L. Dunn An adjunctive polymer system for use with medical device
PT754032E (pt) * 1994-04-08 2002-05-31 Atrix Lab Inc Composicoes liquidas para difusao
US5725869A (en) * 1994-06-20 1998-03-10 Zeneca Limited Microsphere reservoirs for controlled release application
US5616315A (en) * 1994-10-13 1997-04-01 Gillette Canada Inc. Particles including degradable material and anti-microbial agent
US5660817A (en) * 1994-11-09 1997-08-26 Gillette Canada, Inc. Desensitizing teeth with degradable particles
US5607686A (en) * 1994-11-22 1997-03-04 United States Surgical Corporation Polymeric composition
US5779471A (en) * 1995-03-08 1998-07-14 Gillette Canada Inc. Delivery of substance to the mouth
DE69632569T2 (de) * 1995-06-09 2005-08-18 Euroceltique S.A. Formulierungen und verfahren für eine verlängerte lokalanästhesie
US5747060A (en) * 1996-03-26 1998-05-05 Euro-Celtique, S.A. Prolonged local anesthesia with colchicine
SE9601421D0 (sv) * 1996-04-12 1996-04-12 Astra Ab New composition
US5939047A (en) * 1996-04-16 1999-08-17 Jernberg; Gary R. Local delivery of chemotherapeutic agents for treatment of periodontal disease
WO1997044016A1 (en) * 1996-05-23 1997-11-27 Samyang Corporation Locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof
AU733867B2 (en) 1996-06-24 2001-05-31 Euro-Celtique S.A. Methods for providing safe local anesthesia
US6046187A (en) * 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US5972389A (en) * 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
US5918609A (en) 1996-10-24 1999-07-06 Gillette Canada Inc. Particulate modified elastomeric flosses
US5941256A (en) * 1996-12-24 1999-08-24 Gillette Canada Inc. Dental hygiene article
ES2130969B1 (es) * 1997-02-24 2000-02-16 Univ Valencia Estudi General Biomembranas para la encapsulacion extemporanea de tetracaina.
KR100508229B1 (ko) 1997-03-18 2005-08-17 선스타 가부시키가이샤 고체 입자 형성용 조성물
FR2764514B1 (fr) * 1997-06-13 1999-09-03 Biopharmex Holding Sa Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique
KR100367144B1 (ko) 1997-07-02 2003-01-14 유로-셀티크 소시에떼 아노뉨 관절과 체강(body space)내에서 연장된 마취
US6123957A (en) * 1997-07-16 2000-09-26 Jernberg; Gary R. Delivery of agents and method for regeneration of periodontal tissues
US6153210A (en) * 1997-08-14 2000-11-28 Periodontix, Inc. Use of locally delivered metal ions for treatment of periodontal disease
US7846919B2 (en) * 1998-02-10 2010-12-07 Dermex Pharmaceuticals, Llc Chelated 8-hydroxyquinoline and use thereof in a method of treating epithelial lesions
US7128927B1 (en) 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
US6451335B1 (en) 1998-07-02 2002-09-17 Euro-Celtique S.A. Formulations and methods for providing prolonged local anesthesia
US6153225A (en) * 1998-08-13 2000-11-28 Elan Pharma International Limited Injectable formulations of nanoparticulate naproxen
US6165506A (en) * 1998-09-04 2000-12-26 Elan Pharma International Ltd. Solid dose form of nanoparticulate naproxen
US8226598B2 (en) 1999-09-24 2012-07-24 Tolmar Therapeutics, Inc. Coupling syringe system and methods for obtaining a mixed composition
DE19957918A1 (de) * 1999-11-25 2001-06-13 Ulrich Doht Desinfektionsreiniger zur Reinigung und Pflege sowie Verfahren zu seiner Herstellung
US6555125B2 (en) 1999-11-30 2003-04-29 Phillip Campbell Lesion and ulcer medication
US6352711B1 (en) 1999-11-30 2002-03-05 Phillip Campbell Lesion and ulcer medication
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US6589562B1 (en) 2000-10-25 2003-07-08 Salvona L.L.C. Multicomponent biodegradable bioadhesive controlled release system for oral care products
US6565873B1 (en) * 2000-10-25 2003-05-20 Salvona Llc Biodegradable bioadhesive controlled release system of nano-particles for oral care products
US6887493B2 (en) * 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
US20040029842A1 (en) * 2001-12-18 2004-02-12 Gardner Wallace J. Triglyceride lowering, common cold and pneumonia prevention composition comprising tetracycline, and methods of treating or preventing diseases using same
JP4202656B2 (ja) * 2002-02-19 2008-12-24 サンスター株式会社 局所投与型徐放性軟膏
US7074426B2 (en) * 2002-03-27 2006-07-11 Frank Kochinke Methods and drug delivery systems for the treatment of orofacial diseases
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
JP4865330B2 (ja) 2002-12-13 2012-02-01 デュレクト コーポレーション 経口ドラッグデリバリーシステム
US20050079187A1 (en) * 2003-10-14 2005-04-14 Gardner Wallace J. Composition, kit and method for reducing plaque formation, tooth decay and incidence of caries
DK2351555T3 (en) * 2004-02-23 2017-01-23 Euro Celtique Sa Abuse-safe transdermal opioid delivery device
US20070196453A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs
US20070196323A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs
US8907153B2 (en) * 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20070196325A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for dermally treating infections
US20070196452A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Flux-enabling compositions and methods for dermal delivery of drugs
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US20070196457A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US20070190124A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs
US20070196293A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for treating photo damaged skin
US20080019927A1 (en) * 2004-06-07 2008-01-24 Jie Zhang Compositions and methods for dermally treating neuropathy with minoxidil
US20070189978A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for dermally treating musculoskeletal pain
AU2005287175B2 (en) 2004-09-17 2011-12-01 Durect Corporation Sustained local anesthetic composition containing preferably a sugar ester such as SAIB
AU2005299748B2 (en) * 2004-10-21 2009-04-09 Tgel Bio Co., Ltd In situ controlled release drug delivery system
WO2006096893A2 (en) * 2005-03-10 2006-09-14 Marx Management Cc Dental barrier composition
WO2007002041A2 (en) * 2005-06-21 2007-01-04 Foster Corporation Drug-filled polymer films
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
PL2450041T3 (pl) 2005-10-12 2019-02-28 Unimed Pharmaceuticals, Llc Ulepszony żel zawierający testosteron do zastosowania do leczenia hipogonadyzmu
US20070280972A1 (en) * 2006-04-25 2007-12-06 Zars, Inc. Adhesive solid gel-forming formulations for dermal drug delivery
WO2008001325A2 (en) * 2006-06-30 2008-01-03 Piramal Life Sciences Limited Herbal compositions for the treatment of diseases of the oral cavity
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
AU2008347158B8 (en) 2007-12-06 2013-08-22 Durect Corporation Oral pharmaceutical dosage forms
WO2009120889A2 (en) * 2008-03-26 2009-10-01 Alltranz Inc. Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists
US20090311335A1 (en) * 2008-06-12 2009-12-17 Scott Jenkins Combination of a triptan and an nsaid
GB0818473D0 (en) 2008-10-08 2008-11-12 Probio Nutraceuticals As Composition
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
WO2010059917A1 (en) * 2008-11-20 2010-05-27 Water Visions International, Inc. Antimicrobial device and materials for fluid treatment
US9012477B2 (en) * 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
US8481678B2 (en) * 2009-03-30 2013-07-09 E I Du Pont De Nemours And Company Peptide-based tooth whitening reagents
AU2011205730C1 (en) 2010-01-14 2014-10-09 Nuvo Research Inc. Solid-forming local anesthetic formulations for pain control
DE102010033048A1 (de) * 2010-08-02 2012-02-02 Katz Biotech Ag Verwendung eines mikroverkapselten Nahrungssubstrats
WO2012061547A1 (en) * 2010-11-05 2012-05-10 The Research Foundation Of State University Of New York System and method for differentially timed local delivery of a combination pharmaceutical preparation for oral therapy
US9452135B2 (en) 2012-03-20 2016-09-27 Particle Dynamics International, Llc Gelling agent-based dosage form
US20150044147A1 (en) * 2013-02-18 2015-02-12 King Abdullah International Medical Research Center Composition for management of periodontal disease
US9498612B2 (en) 2013-03-14 2016-11-22 Hallux, Inc. Method of treating infections, diseases or disorders of nail unit
TW201521769A (zh) 2013-03-15 2015-06-16 Durect Corp 具有流變改質劑以減少溶解變異性之組成物
CN104784152B (zh) * 2014-01-20 2017-10-24 洛阳惠中兽药有限公司 一种甲砜霉素微囊及其制备方法与应用
DE102016101280A1 (de) * 2016-01-26 2017-07-27 Frank Bröseler Pharmazeutische Zusammensetzung
CN108498854B (zh) * 2018-04-27 2021-06-15 温州医科大学附属第二医院(温州医科大学附属育英儿童医院) 一种负载纳米缓释药物胶束和载银微球的膨胀海绵及其制备方法及用途
US20220218571A1 (en) * 2019-04-18 2022-07-14 Board Of Regents Of The University Of Nebraska Hydrogel drug delivery composition
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3185625A (en) * 1961-11-08 1965-05-25 Brown Ethan Allan Injectionable substances
US3934001A (en) 1965-12-07 1976-01-20 Lever Brothers Company Oral compositions containing germicidally active plastic powders
FR2077696B1 (es) * 1970-02-06 1973-03-16 Synthelabo
US4039653A (en) * 1974-01-23 1977-08-02 Defoney, Brenman, Mayes & Baron Long-acting articles for oral delivery and process
JPS5138412A (en) * 1974-09-24 1976-03-31 Nippon Kayaku Kk Kokoseizai no seiho
US3972995A (en) * 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4188373A (en) * 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4138477A (en) * 1976-05-28 1979-02-06 Colgate Palmolive Company Composition to control mouth odor
US4585651A (en) * 1978-10-17 1986-04-29 Stolle Research & Development Corporation Active/passive immunization of the internal female reproductive organs
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4292028A (en) * 1979-07-13 1981-09-29 Arthur Barr Cosmetic breath freshener and palate coolant composition and method of use
US4622244A (en) * 1979-09-04 1986-11-11 The Washington University Process for preparation of microcapsules
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4434153A (en) * 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
SE8203953D0 (sv) * 1982-06-24 1982-06-24 Astra Laekemedel Ab Pharmaceutical mixture
US4568535A (en) * 1982-08-06 1986-02-04 Loesche Walter J Composition for periodontal administration
US4597960A (en) * 1983-04-19 1986-07-01 Cohen Edgar C Microencapsulated astringent hemostatic agents and methods of use
CA1224148A (en) * 1983-05-16 1987-07-14 John L. Haslam Drug delivery system utilizing thermosetting gels
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4568538A (en) 1984-02-23 1986-02-04 International Flavors & Fragrances Inc. Flavoring with norbornyl pyridine derivatives
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4650665A (en) * 1985-02-08 1987-03-17 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤

Also Published As

Publication number Publication date
NO177125B (no) 1995-04-18
JPS6327422A (ja) 1988-02-05
EP0244118A1 (en) 1987-11-04
JP2698353B2 (ja) 1998-01-19
NO871774D0 (no) 1987-04-28
EP0244118B1 (en) 1993-10-20
NO871774L (no) 1987-10-30
AU614061B2 (en) 1991-08-22
AU7211287A (en) 1987-11-05
NZ219948A (en) 1988-11-29
NO177125C (no) 1995-07-26
CA1309345C (en) 1992-10-27
US4780320A (en) 1988-10-25
DE3787829T2 (de) 1994-05-11
DK219287A (da) 1987-10-30
DE3787829D1 (de) 1993-11-25
DK219287D0 (da) 1987-04-29

Similar Documents

Publication Publication Date Title
MX167175B (es) Sistema de entrega de drogas, con liberacion controlada, para la bolsa periodontal
MY104183A (en) The use of asymmetric membranes in delivery devices.
MX9101391A (es) Composicion farmaceutica en forma de gel,contenida dentro de un envase
ES2132663T3 (es) Puesto de cebo para liberacion de liquido en dos etapas.
ATE23020T1 (de) Reibungsermaessigung unter benutzung viskoelastischer oeberflaechenaktiver mittel.
MX166018B (es) Sistema electrico de aplicador transdermico de medicamentos
YU46983B (sh) Transdermalni sistem koji deluje preko kože
ES2147858T3 (es) Matriz para el suministro transdermico de farmacos.
NO900151D0 (no) Innretning for avgivelse av midler med en gunstig virkning
ATE184191T3 (de) Pharmazeutische formulierung
ATE118345T1 (de) Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen.
ES2100837T3 (es) Esponja hidrofila de poliuretano/poliurea.
ATE235503T1 (de) Kohlenhydraten verwendbar in feste verabreichungssysteme
DK1176961T3 (da) Nikotinafgivende systemer
BR0311897A (pt) Sistema de liberação osmótica com mecanismo de potência de impulso de ordem zero inicial compreendendo um agente osmótico disperso no veìculo fluido
NO165378C (no) Medikamentavgivende innretning for implantering i menneskekroppen.
ATE63059T1 (de) Vorrichtung mit zwei schichten zur freisetzung von arzneimitteln.
ITRM910402A0 (it) Articolo contenente medicamento e dispositivo di erogazione per esso.
CO5011082A1 (es) Formulacion medicamentosa con liberacion controlada de sus- tancia activa
FR2502807B1 (fr) Dispositif d'entrainement intermittent, utilisable notamment dans des dispositifs de remplissage et dans des dispositifs de convoyage
SE9704400D0 (sv) Porous inorganic particles as carriers for drug substances
DK0994887T3 (da) Modificerede glycosider, præparater omfattet deraf og fremgangsmåder til anvendelse deraf
AR246080A1 (es) Agentes de espumosidad en forma granulada.
ES2033085T3 (es) Sistema osmotico para el suministro de soluciones diluidas.
DE69110781D1 (de) Selbstklebendes Matrixsystem für transdermal gesteuerte Abgabe von Piribedil.