ES2098519T3 - Aparato para hacer penetrar medicamentos en los globulos rojos. - Google Patents

Aparato para hacer penetrar medicamentos en los globulos rojos.

Info

Publication number
ES2098519T3
ES2098519T3 ES92915621T ES92915621T ES2098519T3 ES 2098519 T3 ES2098519 T3 ES 2098519T3 ES 92915621 T ES92915621 T ES 92915621T ES 92915621 T ES92915621 T ES 92915621T ES 2098519 T3 ES2098519 T3 ES 2098519T3
Authority
ES
Spain
Prior art keywords
suspension
unit
resealing
pct
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92915621T
Other languages
English (en)
Inventor
Etienne Pages
Claude Ropars
Christophe Bailleul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Communaute Europeenne
Original Assignee
Communaute Europeenne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Communaute Europeenne filed Critical Communaute Europeenne
Application granted granted Critical
Publication of ES2098519T3 publication Critical patent/ES2098519T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/18—Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369—Temperature treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood
    • A61M2202/0429—Red blood cells; Erythrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/366—General characteristics of the apparatus related to heating or cooling by liquid heat exchangers

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Centrifugal Separators (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

LA PRESENTE INVENCION S REFIERE A UN DISPOSITIVO DESTINADO A PERMITIR LA INCORPORACION DE UNA O VARIAS SUSTANCIAS CON ACTIVIDAD BIOLOGICA EN LOS GLOBULOS ROJOS POR LA TECNICA DE LISIS/RESELLADO, CARACTERIZADO EN QUE COMPRENDE: UNA UNIDAD DE LAVADO QUE PERMITE, A PARTIR DE UNA SANGRE COMPLETA O NO, LA OBTENCION DE UNA SUSPENSION DE HEMATIES; UNA UNIDA DE LISIS Y RESELLADO CONSTITUIDA POR UN MODULO DE LISIS (A) A UNA TEMPERATURA INFERIOR A 10 (GRADOS) C Y POR UN MODULO DE RESELLADO (B) A UNA TEMPERATURA SUPERIOR A 20 (GRADOS) C, ESTANDO CONCEBIDO EL CONJUNTO DE LOS ELEMENTOS DE LA UNIDAD DE LISIS Y RESELLADO QUE ESTA EN CONTACTO CON LA SUSPENSION DE ERITROCITOS PARA UN UNICO USO.
ES92915621T 1991-07-03 1992-07-02 Aparato para hacer penetrar medicamentos en los globulos rojos. Expired - Lifetime ES2098519T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9108302A FR2678512B1 (fr) 1991-07-03 1991-07-03 Machine a internaliser.

Publications (1)

Publication Number Publication Date
ES2098519T3 true ES2098519T3 (es) 1997-05-01

Family

ID=9414655

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92915621T Expired - Lifetime ES2098519T3 (es) 1991-07-03 1992-07-02 Aparato para hacer penetrar medicamentos en los globulos rojos.

Country Status (13)

Country Link
US (1) US5589389A (es)
EP (1) EP0679101B1 (es)
JP (1) JP3148239B2 (es)
AT (1) ATE149846T1 (es)
CA (1) CA2112685A1 (es)
DE (1) DE69218265T2 (es)
DK (1) DK0679101T3 (es)
ES (1) ES2098519T3 (es)
FI (1) FI935940A (es)
FR (1) FR2678512B1 (es)
GR (1) GR3023360T3 (es)
NO (1) NO306327B1 (es)
WO (1) WO1993000940A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0882448B1 (en) * 1997-05-05 2005-01-12 DIDECO S.r.l. Method of encapsulating biologically active agents within erythrocytes and apparatus therefor
MXPA05001355A (es) 2002-08-05 2005-09-30 Atugen Ag Formas nuevas adicionales de moleculas de arn de interferencia.
FR2873925B1 (fr) * 2004-08-05 2006-10-13 Erytech Pharma Soc Par Actions Procede et dispositif de lyse-rescellement pour l'incorporation de principe actif notamment asparaginase ou inositol hexaphosphate, dans des erythrocytes
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
FR2919804B1 (fr) 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
CA2715379A1 (en) * 2008-02-13 2009-08-20 Erytech Pharma Formulation and method for the prevention and treatment of skeletal manifestation of gaucher's disease
FR2928270B1 (fr) * 2008-03-10 2011-01-21 Erytech Pharma Formulation methode pour la prevention ou le traitement des metastases osseuses et autres maladies de l'os
FR2940087B1 (fr) 2008-12-18 2011-05-06 Lab Francais Du Fractionnement Erythrocytes contenant du facteur viii, preparation et utilisations.
IT1399590B1 (it) * 2010-04-26 2013-04-26 Erydel Spa Apparato e kit per incapsulare almeno un composto ad uso terapeutico e/o diagnostico all'interno di eritrociti
AU2013237419B2 (en) 2012-03-21 2016-04-28 Erytech Pharma Medicament for the treatment of acute myeloid leukemia (AML)
FR3005420B1 (fr) 2013-05-07 2015-09-18 Erytech Pharma Procede de stabilisation de suspensions d'erythrocytes encapsulant un principe actif, suspensions obtenues.
EP2813234A1 (en) 2013-06-11 2014-12-17 Erytech Pharma Composition of erythrocytes encapsulating phenylalanine hydroxylase and therapeutic use thereof
WO2017041051A1 (en) 2015-09-04 2017-03-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
IT202100023375A1 (it) * 2021-09-09 2023-03-09 Yang Shunfa Dispositivo per la produzione di vescicole bioingegnerizzate dedicate e metodo correlato

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1501134B2 (de) * 1966-02-02 1976-08-12 Siemens AG, 1000 Berlin und 8000 München Vorrichtung zur veraenderung der temperatur von blut
US3839204A (en) * 1972-04-27 1974-10-01 Gen Electric Integral blood heat and component exchange device and two flow path membrane blood gas exchanger
US3853479A (en) * 1972-06-23 1974-12-10 Sherwood Medical Ind Inc Blood oxygenating device with heat exchanger
US4327710A (en) * 1980-06-18 1982-05-04 The United States Of America As Represented By The Secretary Of Agriculture Process for encapsulating additives in resealed erythrocytes for disseminating chemicals via the circulatory system
US4517080A (en) * 1980-06-18 1985-05-14 The United States Of America As Represented By The Secretary Of Agriculture Apparatus for encapsulating additives in resealed erythrocytes
FR2529463B1 (fr) * 1982-07-05 1986-01-10 Centre Nat Rech Scient Procede et dispositif pour l'encapsulation dans les erythrocytes d'au moins une substance a activite biologique, notamment des effecteurs allosteriques de l'hemoglobine et erythrocytes ainsi obtenus
US4668214A (en) * 1986-06-09 1987-05-26 Electromedics, Inc. Method of washing red blood cells
NL8701233A (nl) * 1987-05-22 1988-12-16 Medistad Holland Bloedverwarmingstoestel.

Also Published As

Publication number Publication date
GR3023360T3 (en) 1997-08-29
EP0679101A1 (fr) 1995-11-02
CA2112685A1 (fr) 1993-01-21
EP0679101B1 (fr) 1997-03-12
FR2678512B1 (fr) 1995-06-30
DE69218265D1 (de) 1997-04-17
FR2678512A1 (fr) 1993-01-08
JPH06509250A (ja) 1994-10-20
DK0679101T3 (da) 1997-09-22
FI935940A0 (fi) 1993-12-30
US5589389A (en) 1996-12-31
NO934899D0 (no) 1993-12-29
NO934899L (no) 1994-03-01
FI935940A (fi) 1994-02-17
ATE149846T1 (de) 1997-03-15
DE69218265T2 (de) 1997-08-14
WO1993000940A1 (fr) 1993-01-21
NO306327B1 (no) 1999-10-25
JP3148239B2 (ja) 2001-03-19

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