DE3787829D1 - System für die Periodontaltasche zur kontrollierten Drogenfreisetzung. - Google Patents

System für die Periodontaltasche zur kontrollierten Drogenfreisetzung.

Info

Publication number
DE3787829D1
DE3787829D1 DE87303275T DE3787829T DE3787829D1 DE 3787829 D1 DE3787829 D1 DE 3787829D1 DE 87303275 T DE87303275 T DE 87303275T DE 3787829 T DE3787829 T DE 3787829T DE 3787829 D1 DE3787829 D1 DE 3787829D1
Authority
DE
Germany
Prior art keywords
drug release
controlled drug
pouch system
periodontal pouch
periodontal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87303275T
Other languages
English (en)
Other versions
DE3787829T2 (de
Inventor
Richard W Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PharMetrix Corp
Original Assignee
PharMetrix Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25324860&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3787829(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PharMetrix Corp filed Critical PharMetrix Corp
Application granted granted Critical
Publication of DE3787829D1 publication Critical patent/DE3787829D1/de
Publication of DE3787829T2 publication Critical patent/DE3787829T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/15—Compositions characterised by their physical properties
    • A61K6/17—Particle size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)
DE87303275T 1986-04-29 1987-04-14 System für die Periodontaltasche zur kontrollierten Drogenfreisetzung. Expired - Fee Related DE3787829T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/856,961 US4780320A (en) 1986-04-29 1986-04-29 Controlled release drug delivery system for the periodontal pocket

Publications (2)

Publication Number Publication Date
DE3787829D1 true DE3787829D1 (de) 1993-11-25
DE3787829T2 DE3787829T2 (de) 1994-05-11

Family

ID=25324860

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87303275T Expired - Fee Related DE3787829T2 (de) 1986-04-29 1987-04-14 System für die Periodontaltasche zur kontrollierten Drogenfreisetzung.

Country Status (10)

Country Link
US (1) US4780320A (de)
EP (1) EP0244118B1 (de)
JP (1) JP2698353B2 (de)
AU (1) AU614061B2 (de)
CA (1) CA1309345C (de)
DE (1) DE3787829T2 (de)
DK (1) DK219287A (de)
MX (1) MX167175B (de)
NO (1) NO177125C (de)
NZ (1) NZ219948A (de)

Families Citing this family (136)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
US5500228A (en) * 1987-05-26 1996-03-19 American Cyanamid Company Phase separation-microencapsulated pharmaceuticals compositions useful for alleviating dental disease
US5175000A (en) * 1987-06-30 1992-12-29 Vipont Pharmaceutical, Inc. Free amine benzophenanthridine alkaloid compositions
US5013553A (en) * 1987-06-30 1991-05-07 Vipont Pharmaceutical, Inc. Drug delivery devices
US4843099A (en) * 1987-07-20 1989-06-27 Colgate-Palmolive Company Device and composition for treatment of the gums
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5632727A (en) * 1988-10-03 1997-05-27 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
US5324520A (en) * 1988-12-19 1994-06-28 Vipont Pharmaceutical, Inc. Intragingival delivery systems for treatment of periodontal disease
US5236355A (en) * 1988-12-22 1993-08-17 American Cyanamid Company Apparatus for the treatment of periodontal disease
EP0374532B1 (de) * 1988-12-22 1994-09-21 American Cyanamid Company Durch Phasentrennung microinkapsulierte Arzneimittelzusammensetzung zur Verminderung der Zahnkrankheit
DE68915132T2 (de) * 1988-12-22 1994-12-08 American Cyanamid Co., Wayne, N.J. Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung.
US5007790A (en) * 1989-04-11 1991-04-16 Depomed Systems, Inc. Sustained-release oral drug dosage form
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US5077049A (en) * 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
US5143934A (en) * 1990-11-21 1992-09-01 A/S Dumex (Dumex Ltd.) Method and composition for controlled delivery of biologically active agents
US5198220A (en) * 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US4997830A (en) * 1990-02-07 1991-03-05 The Research Foundation Of State University Of New York Pharmaceutical composition for the treatment of periodontitis
US5464609A (en) * 1990-03-16 1995-11-07 The Procter & Gamble Company Use of ketorolac for treatment of oral diseases and conditions
AU629316B2 (en) * 1990-04-11 1992-10-01 Flora Inc. Periodontal disease treatment system
USRE37950E1 (en) 1990-04-24 2002-12-31 Atrix Laboratories Biogradable in-situ forming implants and methods of producing the same
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
US5197882A (en) * 1990-05-14 1993-03-30 Gary R. Jernberg Periodontal barrier and method for aiding periodontal tissue regeneration agents
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
EP0489743A1 (de) * 1990-07-03 1992-06-17 Vipont Pharmaceutical, Inc. Intragingivale vorrichtung zur verabreichung von wirkstoffen zur behandlung paradontaler krankheiten
AU8935591A (en) * 1990-10-30 1992-05-26 Alza Corporation Drug delivery system and method
US5620700A (en) * 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
US5770588A (en) * 1991-02-11 1998-06-23 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions of the prevention and treatment of root caries
US5906834A (en) * 1992-06-15 1999-05-25 The Gillette Company Color changing matrix as wear indicator
US5340581A (en) * 1991-08-23 1994-08-23 Gillette Canada, Inc. Sustained-release matrices for dental application
ATE173893T1 (de) * 1991-08-23 1998-12-15 Gillette Co Matrizen mit verzögerter freisetzung für dentalzwecke
WO1993005680A1 (en) * 1991-09-13 1993-04-01 Gillette Canada Inc. Polymeric particles for dental applications
AU704007B2 (en) * 1991-09-13 1999-04-01 Gillette Canada Inc. Toothbrushes
US5211939A (en) * 1991-09-13 1993-05-18 Gillette Canada Method for desensitizing teeth
US5250288A (en) * 1991-09-13 1993-10-05 Gillette Canada, Inc. Method for desensitizing teeth
US5364634A (en) * 1991-11-08 1994-11-15 Southwest Research Institute Controlled-release PH sensitive capsule and adhesive system and method
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
EP0560014A1 (de) * 1992-03-12 1993-09-15 Atrix Laboratories, Inc. Biologisch abbaubarer Wundverband in Form eines Sprühfilms und Verfahren zu seiner Herstellung
WO1993019739A1 (en) * 1992-03-30 1993-10-14 Alza Corporation Viscous suspensions of controlled-release drug particles
AU3941793A (en) * 1992-03-30 1993-11-08 Alza Corporation Additives for bioerodible polymers to regulate degradation
JP3007687B2 (ja) * 1992-09-10 2000-02-07 チルドレンズ メディカル センター コーポレイション 局所麻酔剤の持続性送達のための生分解性ポリマーマトリックス
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5242910A (en) * 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5447725A (en) * 1993-06-11 1995-09-05 The Procter & Gamble Company Methods for aiding periodontal tissue regeneration
EP0707465A4 (de) * 1993-07-08 1997-04-16 Cygnus Therapeutic Systems Monolithisches matrix transdermales abgabesystem
WO1995022308A1 (en) * 1994-02-17 1995-08-24 The Oralife Group, Inc. Method for the diagnosis and reduction of dental caries
US5502092A (en) * 1994-02-18 1996-03-26 Minnesota Mining And Manufacturing Company Biocompatible porous matrix of bioabsorbable material
JPH09511666A (ja) * 1994-04-08 1997-11-25 アトリックス・ラボラトリーズ・インコーポレイテッド 医療装置で使用する付随的ポリマー系
ATE209907T1 (de) * 1994-04-08 2001-12-15 Atrix Lab Inc Flüssige mittel zur wirkstoffabgabe
US5725869A (en) * 1994-06-20 1998-03-10 Zeneca Limited Microsphere reservoirs for controlled release application
US5616315A (en) * 1994-10-13 1997-04-01 Gillette Canada Inc. Particles including degradable material and anti-microbial agent
US5660817A (en) * 1994-11-09 1997-08-26 Gillette Canada, Inc. Desensitizing teeth with degradable particles
US5607686A (en) * 1994-11-22 1997-03-04 United States Surgical Corporation Polymeric composition
US5779471A (en) * 1995-03-08 1998-07-14 Gillette Canada Inc. Delivery of substance to the mouth
AU706541B2 (en) * 1995-06-09 1999-06-17 Euro-Celtique S.A. Formulations and methods for providing prolonged local anesthesia
US5747060A (en) * 1996-03-26 1998-05-05 Euro-Celtique, S.A. Prolonged local anesthesia with colchicine
SE9601421D0 (sv) * 1996-04-12 1996-04-12 Astra Ab New composition
US5939047A (en) * 1996-04-16 1999-08-17 Jernberg; Gary R. Local delivery of chemotherapeutic agents for treatment of periodontal disease
WO1997044016A1 (en) * 1996-05-23 1997-11-27 Samyang Corporation Locally administrable, biodegradable and sustained-release pharmaceutical composition for periodontitis and process for preparation thereof
EP0954301A4 (de) 1996-06-24 2006-03-08 Euro Celtique Sa Verfahren zur erzeugung einer sicheren lokalen anästhesie
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US5972389A (en) * 1996-09-19 1999-10-26 Depomed, Inc. Gastric-retentive, oral drug dosage forms for the controlled-release of sparingly soluble drugs and insoluble matter
US5918609A (en) 1996-10-24 1999-07-06 Gillette Canada Inc. Particulate modified elastomeric flosses
US5941256A (en) * 1996-12-24 1999-08-24 Gillette Canada Inc. Dental hygiene article
ES2130969B1 (es) * 1997-02-24 2000-02-16 Univ Valencia Estudi General Biomembranas para la encapsulacion extemporanea de tetracaina.
CA2283830C (en) 1997-03-18 2008-07-22 Sunstar Inc. Composition for forming solid particles
FR2764514B1 (fr) 1997-06-13 1999-09-03 Biopharmex Holding Sa Implant injectable en sous-cutane ou intradermique a bioresorbabilite controlee pour la chirurgie reparatrice ou plastique et la dermatologie esthetique
WO1999001114A1 (en) * 1997-07-02 1999-01-14 Euro-Celtique, S.A. Prolonged anesthesia in joints and body spaces
US6123957A (en) * 1997-07-16 2000-09-26 Jernberg; Gary R. Delivery of agents and method for regeneration of periodontal tissues
US6153210A (en) * 1997-08-14 2000-11-28 Periodontix, Inc. Use of locally delivered metal ions for treatment of periodontal disease
US7846919B2 (en) * 1998-02-10 2010-12-07 Dermex Pharmaceuticals, Llc Chelated 8-hydroxyquinoline and use thereof in a method of treating epithelial lesions
US7128927B1 (en) 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
US6451335B1 (en) 1998-07-02 2002-09-17 Euro-Celtique S.A. Formulations and methods for providing prolonged local anesthesia
US6153225A (en) * 1998-08-13 2000-11-28 Elan Pharma International Limited Injectable formulations of nanoparticulate naproxen
US6165506A (en) * 1998-09-04 2000-12-26 Elan Pharma International Ltd. Solid dose form of nanoparticulate naproxen
US8226598B2 (en) 1999-09-24 2012-07-24 Tolmar Therapeutics, Inc. Coupling syringe system and methods for obtaining a mixed composition
DE19957918A1 (de) * 1999-11-25 2001-06-13 Ulrich Doht Desinfektionsreiniger zur Reinigung und Pflege sowie Verfahren zu seiner Herstellung
US6555125B2 (en) 1999-11-30 2003-04-29 Phillip Campbell Lesion and ulcer medication
US6352711B1 (en) 1999-11-30 2002-03-05 Phillip Campbell Lesion and ulcer medication
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US6589562B1 (en) 2000-10-25 2003-07-08 Salvona L.L.C. Multicomponent biodegradable bioadhesive controlled release system for oral care products
US6565873B1 (en) 2000-10-25 2003-05-20 Salvona Llc Biodegradable bioadhesive controlled release system of nano-particles for oral care products
US6887493B2 (en) * 2000-10-25 2005-05-03 Adi Shefer Multi component controlled release system for oral care, food products, nutraceutical, and beverages
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6610274B1 (en) * 2000-12-22 2003-08-26 Wallace J. Gardner Anti-inflammatory composition comprising tetracycline
US20040029842A1 (en) * 2001-12-18 2004-02-12 Gardner Wallace J. Triglyceride lowering, common cold and pneumonia prevention composition comprising tetracycline, and methods of treating or preventing diseases using same
JP4202656B2 (ja) * 2002-02-19 2008-12-24 サンスター株式会社 局所投与型徐放性軟膏
US7074426B2 (en) * 2002-03-27 2006-07-11 Frank Kochinke Methods and drug delivery systems for the treatment of orofacial diseases
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
SI2218448T1 (sl) 2002-12-13 2016-01-29 Durect Corporation Sistem za oralno dajanje zdravila, ki obsega tekoči nosilec materialov z visoko viskoznostjo
US20050079187A1 (en) * 2003-10-14 2005-04-14 Gardner Wallace J. Composition, kit and method for reducing plaque formation, tooth decay and incidence of caries
JP2007523167A (ja) * 2004-02-23 2007-08-16 ユーロ−セルティーク エス．エイ． 乱用抵抗性の経皮的オピオイド送達デバイス
US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US20080019927A1 (en) * 2004-06-07 2008-01-24 Jie Zhang Compositions and methods for dermally treating neuropathy with minoxidil
US20070190124A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs
US20070196452A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Flux-enabling compositions and methods for dermal delivery of drugs
US20070196293A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for treating photo damaged skin
US20070196325A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for dermally treating infections
US20070196453A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs
US8907153B2 (en) * 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20070189978A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for dermally treating musculoskeletal pain
US20070196457A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
US20070196323A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
EA201001885A1 (ru) 2004-09-17 2011-12-30 Дьюрект Корпорейшн Система контролируемой доставки
EP1807018A4 (de) * 2004-10-21 2012-07-04 Univ Iowa Res Found System zur kontrollierten in-situ-verabreichung von arzneimitteln
WO2006096893A2 (en) * 2005-03-10 2006-09-14 Marx Management Cc Dental barrier composition
WO2007002041A2 (en) * 2005-06-21 2007-01-04 Foster Corporation Drug-filled polymer films
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
SI2450041T1 (sl) 2005-10-12 2019-02-28 Unimed Pharmaceuticals, Llc Izboljšan testosteronski gel za uporabo pri zdravljenju hipogonadizma
US20070280972A1 (en) * 2006-04-25 2007-12-06 Zars, Inc. Adhesive solid gel-forming formulations for dermal drug delivery
JP2009542620A (ja) * 2006-06-30 2009-12-03 ピラマル・ライフ・サイエンシーズ・リミテッド 口腔疾患治療用の薬草組成物
PT2117521E (pt) 2006-11-03 2012-09-10 Durect Corp Sistemas de administração transdérmica que compreendem bupivacaína
AU2008335809A1 (en) 2007-12-06 2009-06-18 Durect Corporation Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
MX2010010512A (es) * 2008-03-26 2010-11-09 Alltranz Inc Formulaciones transdermicas de agonistas y antagonistas-agonistas de opiato que impiden el abuso.
US20090311335A1 (en) * 2008-06-12 2009-12-17 Scott Jenkins Combination of a triptan and an nsaid
GB0818473D0 (en) 2008-10-08 2008-11-12 Probio Nutraceuticals As Composition
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
BRPI0921066A2 (pt) * 2008-11-20 2015-12-15 Water Visions International Inc composição, método para inativar contaminantes microbiológicos em um fluido, método para fabricar um material polimérico antimicrobiano, e, dispositivo para tratamento antimicrobiano de um fluido
US9012477B2 (en) * 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
US8481678B2 (en) * 2009-03-30 2013-07-09 E I Du Pont De Nemours And Company Peptide-based tooth whitening reagents
CN102834096A (zh) 2010-01-14 2012-12-19 卢福研究公司 用于疼痛控制的固态成型局部麻醉制剂
DE102010033048A1 (de) * 2010-08-02 2012-02-02 Katz Biotech Ag Verwendung eines mikroverkapselten Nahrungssubstrats
US20140205662A1 (en) * 2010-11-05 2014-07-24 The Research Foundation For The State University Of New York System and method for differentially timed local delivery of a combination pharmaceutical preparation for oral therapy
EP2827839B1 (de) 2012-03-20 2019-02-27 Particle Dynamics International, LLC Dosierungsform auf basis eines gelierungsmittels
US20150044147A1 (en) * 2013-02-18 2015-02-12 King Abdullah International Medical Research Center Composition for management of periodontal disease
CN105377355A (zh) 2013-03-14 2016-03-02 拇趾公司 治疗甲单元的感染、疾病或病症的方法
CN105120659A (zh) 2013-03-15 2015-12-02 度瑞公司 用于降低溶解可变性的具有流变改性剂的组合物
CN104784152B (zh) * 2014-01-20 2017-10-24 洛阳惠中兽药有限公司 一种甲砜霉素微囊及其制备方法与应用
DE102016101280A1 (de) * 2016-01-26 2017-07-27 Frank Bröseler Pharmazeutische Zusammensetzung
CN108498854B (zh) * 2018-04-27 2021-06-15 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） 一种负载纳米缓释药物胶束和载银微球的膨胀海绵及其制备方法及用途
CA3146153A1 (en) * 2019-04-18 2020-10-22 Board Of Regents Of The University Of Nebraska Hydrogel drug delivery composition
EP4090353A4 (de) 2020-01-13 2023-08-09 Durect Corporation Arzneimittelabgabesysteme mit verzögerter freisetzung mit reduzierten verunreinigungen und verwandte verfahren

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3185625A (en) * 1961-11-08 1965-05-25 Brown Ethan Allan Injectionable substances
US3934001A (en) 1965-12-07 1976-01-20 Lever Brothers Company Oral compositions containing germicidally active plastic powders
FR2077696B1 (de) * 1970-02-06 1973-03-16 Synthelabo
US4039653A (en) * 1974-01-23 1977-08-02 Defoney, Brenman, Mayes & Baron Long-acting articles for oral delivery and process
JPS5138412A (en) * 1974-09-24 1976-03-31 Nippon Kayaku Kk Kokoseizai no seiho
US3972995A (en) * 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4188373A (en) * 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4138477A (en) * 1976-05-28 1979-02-06 Colgate Palmolive Company Composition to control mouth odor
US4585651A (en) * 1978-10-17 1986-04-29 Stolle Research & Development Corporation Active/passive immunization of the internal female reproductive organs
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4292028A (en) * 1979-07-13 1981-09-29 Arthur Barr Cosmetic breath freshener and palate coolant composition and method of use
US4622244A (en) * 1979-09-04 1986-11-11 The Washington University Process for preparation of microcapsules
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
US4434153A (en) * 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
SE8203953D0 (sv) * 1982-06-24 1982-06-24 Astra Laekemedel Ab Pharmaceutical mixture
US4568535A (en) * 1982-08-06 1986-02-04 Loesche Walter J Composition for periodontal administration
US4597960A (en) * 1983-04-19 1986-07-01 Cohen Edgar C Microencapsulated astringent hemostatic agents and methods of use
CA1224148A (en) * 1983-05-16 1987-07-14 John L. Haslam Drug delivery system utilizing thermosetting gels
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
JPS60100516A (ja) * 1983-11-04 1985-06-04 Takeda Chem Ind Ltd 徐放型マイクロカプセルの製造法
US4568538A (en) 1984-02-23 1986-02-04 International Flavors & Fragrances Inc. Flavoring with norbornyl pyridine derivatives
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4650665A (en) * 1985-02-08 1987-03-17 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤

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AU614061B2 (en) 1991-08-22
EP0244118A1 (de) 1987-11-04
NO177125C (no) 1995-07-26
NZ219948A (en) 1988-11-29
US4780320A (en) 1988-10-25
JP2698353B2 (ja) 1998-01-19
EP0244118B1 (de) 1993-10-20
AU7211287A (en) 1987-11-05
CA1309345C (en) 1992-10-27
DK219287A (da) 1987-10-30
DK219287D0 (da) 1987-04-29
DE3787829T2 (de) 1994-05-11
NO871774L (no) 1987-10-30
MX167175B (es) 1993-03-08
NO871774D0 (no) 1987-04-28
NO177125B (no) 1995-04-18
JPS6327422A (ja) 1988-02-05

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