MEP54308A - Aerosolna formulacija za inhaliranje koja sadrži triotropijumovu so - Google Patents

Aerosolna formulacija za inhaliranje koja sadrži triotropijumovu so

Info

Publication number
MEP54308A
MEP54308A MEP-543/08A MEP54308A MEP54308A ME P54308 A MEP54308 A ME P54308A ME P54308 A MEP54308 A ME P54308A ME P54308 A MEP54308 A ME P54308A
Authority
ME
Montenegro
Prior art keywords
inhalation
aerosol formulation
tiotropium salt
active substance
tiotropium
Prior art date
Application number
MEP-543/08A
Other languages
English (en)
Inventor
Karin Drechsel
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28458728&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MEP54308(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MEP54308A publication Critical patent/MEP54308A/hr
Publication of ME00359B publication Critical patent/ME00359B/me

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nozzles (AREA)

Abstract

Ovaj pronalazak odnosi se na aerosolnu formulaciju bez potisnog gasa, farmaceutski prihvatljive soli tiotropijuma, rastvorene u vodi. Formulacija, na osnovu pronalaska, naročito je pogodna za prevođenje djelotvorne supstance u stanje magle, pomoću atomizera (raspršivača, sprejera), da bi djelotvorna supstanca mogla da se primijeni inhalativno, prvenstveno kod astme i COPD-a.
MEP-2008-543A 2002-04-11 2003-04-02 Aerosolna formulacija za inhaliranje koja sadrži so tiotropijuma ME00359B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10216036A DE10216036A1 (de) 2002-04-11 2002-04-11 Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
YUP-879/04A RS50923B (sr) 2002-04-11 2003-04-02 Aerosolna formulacija za inhaliranje koja sadrži so tiotropijuma
PCT/EP2003/003438 WO2003084519A2 (de) 2002-04-11 2003-04-02 Aerosolformulierung für die inhalation enthaltend ein tiotropiumsalz

Publications (2)

Publication Number Publication Date
MEP54308A true MEP54308A (hr) 2011-05-10
ME00359B ME00359B (me) 2011-10-10

Family

ID=28458728

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2008-543A ME00359B (me) 2002-04-11 2003-04-02 Aerosolna formulacija za inhaliranje koja sadrži so tiotropijuma

Country Status (33)

Country Link
EP (2) EP1496876B1 (hr)
JP (1) JP2005531528A (hr)
KR (1) KR100997219B1 (hr)
CN (1) CN1309378C (hr)
AR (1) AR039286A1 (hr)
AT (1) ATE389391T1 (hr)
AU (1) AU2003222791B2 (hr)
BR (1) BR0309080A (hr)
CA (1) CA2473815C (hr)
CO (1) CO5611150A2 (hr)
CY (1) CY1108133T1 (hr)
DE (2) DE10216036A1 (hr)
DK (1) DK1496876T3 (hr)
EA (1) EA007228B1 (hr)
EC (1) ECSP045358A (hr)
ES (1) ES2303897T3 (hr)
HK (1) HK1078793A1 (hr)
HR (1) HRP20040932B1 (hr)
ME (1) ME00359B (hr)
MX (1) MXPA04009818A (hr)
MY (1) MY137249A (hr)
NO (1) NO334915B1 (hr)
PE (1) PE20030970A1 (hr)
PL (1) PL371204A1 (hr)
PT (1) PT1496876E (hr)
RS (1) RS50923B (hr)
SA (1) SA03240192B1 (hr)
SI (1) SI1496876T1 (hr)
TW (1) TWI344851B (hr)
UA (1) UA78994C2 (hr)
UY (1) UY27754A1 (hr)
WO (1) WO2003084519A2 (hr)
ZA (1) ZA200405721B (hr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG137859A1 (en) 2003-11-03 2007-12-28 Boehringer Ingelheim Int Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
NZ566399A (en) * 2005-08-06 2011-07-29 Boehringer Ingelheim Int Use of tiotropium salts in the treatment of severe persistant asthma
US20070088030A1 (en) 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
EP1905440A1 (de) * 2006-09-06 2008-04-02 Boehringer Ingelheim Pharma GmbH & Co. KG Verwendung einer pharmazeutischen Zusammensetzung enthaltend ein Anticholinergikum zur Abtötung von Mikroorganismen und zur Behandlung von Atemwegsinfektionen
EP2044967A1 (de) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Zerstäuber
WO2013127738A1 (de) 2012-02-28 2013-09-06 Boehringer Ingelheim International Gmbh Neue treibgashaltige tiotropium-formulierung
RU2493827C1 (ru) * 2012-10-03 2013-09-27 Шолекс Девелопмент Гмбх Стабильный комбинированный раствор фенотерола гидробромида и ипратропия бромида
WO2015065219A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Раствор ипратропия бромида
WO2015065223A1 (ru) * 2013-10-28 2015-05-07 Шолекс Девелопмент Гмбх Стабильный раствор фенотерола гидробромида
GB201507686D0 (en) * 2015-05-05 2015-06-17 Norton Healthcare Ltd A stable tiotropium nebuliser solution
AU2017363041A1 (en) * 2016-11-16 2019-04-11 Glenmark Specialty S.A. Nebulized tiotropium
US20210290568A1 (en) * 2020-03-19 2021-09-23 Cai Gu Huang Inhalable formulation of a solution containing levalbuterol tartrate
CN114259481A (zh) * 2021-11-26 2022-04-01 南京华盖制药有限公司 一种奥达特罗复方吸入溶液

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SG45171A1 (en) 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
IL107120A (en) 1992-09-29 1997-09-30 Boehringer Ingelheim Int Atomising nozzle and filter and spray generating device
DE19536903C2 (de) 1995-10-04 1998-09-10 Boehringer Ingelheim Int Vorrichtung zum Haltern eines fluidischen Bauteils
DE19536902A1 (de) 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19545226C1 (de) 1995-12-05 1997-06-19 Boehringer Ingelheim Int Sperrspannwerk für einen federbetätigten Abtrieb
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE19742439C1 (de) 1997-09-26 1998-10-22 Boehringer Ingelheim Int Mikrostrukturiertes Filter
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen
EP1837021A3 (de) * 2000-10-31 2008-03-19 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalative Lösungsformulierung mit einem Tiotropiumsalz

Also Published As

Publication number Publication date
AU2003222791A1 (en) 2003-10-20
PL371204A1 (en) 2005-06-13
CA2473815A1 (en) 2003-10-16
CO5611150A2 (es) 2006-02-28
SI1496876T1 (sl) 2008-08-31
ZA200405721B (en) 2006-05-31
EP1949892A1 (de) 2008-07-30
PT1496876E (pt) 2008-04-15
RS87904A (en) 2006-12-15
SA03240192B1 (ar) 2008-01-09
ES2303897T3 (es) 2008-09-01
WO2003084519A3 (de) 2003-12-24
HRP20040932A2 (en) 2005-02-28
BR0309080A (pt) 2005-02-22
KR100997219B1 (ko) 2010-11-29
DE50309414D1 (de) 2008-04-30
DK1496876T3 (da) 2008-06-02
AR039286A1 (es) 2005-02-16
DE10216036A1 (de) 2003-10-23
MY137249A (en) 2009-01-30
EP1496876A2 (de) 2005-01-19
HRP20040932B1 (hr) 2013-04-30
ECSP045358A (es) 2004-11-26
UA78994C2 (uk) 2007-05-10
ATE389391T1 (de) 2008-04-15
TW200401653A (en) 2004-02-01
NO20044001L (no) 2004-10-27
EA200401305A1 (ru) 2005-06-30
UY27754A1 (es) 2003-11-28
MXPA04009818A (es) 2004-12-13
NO334915B1 (no) 2014-07-14
CN1309378C (zh) 2007-04-11
EP1496876B1 (de) 2008-03-19
ME00359B (me) 2011-10-10
CA2473815C (en) 2011-06-14
HK1078793A1 (en) 2006-03-24
CY1108133T1 (el) 2014-02-12
KR20040097322A (ko) 2004-11-17
EA007228B1 (ru) 2006-08-25
RS50923B (sr) 2010-08-31
WO2003084519A2 (de) 2003-10-16
AU2003222791B2 (en) 2008-09-25
JP2005531528A (ja) 2005-10-20
CN1646108A (zh) 2005-07-27
PE20030970A1 (es) 2004-01-13
TWI344851B (en) 2011-07-11

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