ME03312B - Vorтiokseтin piroglutamat - Google Patents

Vorтiokseтin piroglutamat

Info

Publication number
ME03312B
ME03312B MEP-2019-11A MEP201911A ME03312B ME 03312 B ME03312 B ME 03312B ME P201911 A MEP201911 A ME P201911A ME 03312 B ME03312 B ME 03312B
Authority
ME
Montenegro
Prior art keywords
vortoxette
drawn
vortoxette drawn
Prior art date
Application number
MEP-2019-11A
Other languages
German (de)
English (en)
French (fr)
Inventor
Diego Heidi Lopez De
Kim Lasse Christensen
Rene Holm
Jens Kateb
Original Assignee
H Lundbeck As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55963369&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME03312(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by H Lundbeck As filed Critical H Lundbeck As
Publication of ME03312B publication Critical patent/ME03312B/me

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/282-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
MEP-2019-11A 2015-05-13 2016-05-11 Vorтiokseтin piroglutamat ME03312B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201500284 2015-05-13
EP16721817.1A EP3294719B1 (en) 2015-05-13 2016-05-11 Vortioxetine pyroglutamate
PCT/EP2016/060540 WO2016180870A1 (en) 2015-05-13 2016-05-11 Vortioxetine pyroglutamate

Publications (1)

Publication Number Publication Date
ME03312B true ME03312B (me) 2019-10-20

Family

ID=55963369

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2019-11A ME03312B (me) 2015-05-13 2016-05-11 Vorтiokseтin piroglutamat

Country Status (44)

Country Link
US (2) US10287261B2 (me)
EP (1) EP3294719B1 (me)
JP (1) JP6731001B2 (me)
KR (1) KR102551429B1 (me)
CN (1) CN107567440B (me)
AR (1) AR104591A1 (me)
AU (1) AU2016259762B2 (me)
BR (1) BR112017024039B8 (me)
CA (1) CA2984615C (me)
CL (1) CL2017002844A1 (me)
CO (1) CO2017011295A2 (me)
CR (1) CR20170506A (me)
CY (1) CY1121171T1 (me)
DK (1) DK3294719T3 (me)
DO (1) DOP2017000260A (me)
EA (1) EA032363B1 (me)
EC (1) ECSP17074919A (me)
ES (1) ES2709362T3 (me)
GE (2) GEAP201914622A (me)
HK (1) HK1252099B (me)
HR (1) HRP20190089T1 (me)
HU (1) HUE042893T2 (me)
IL (1) IL255466B (me)
JO (1) JO3456B1 (me)
LT (1) LT3294719T (me)
MA (1) MA43397A (me)
ME (1) ME03312B (me)
MX (1) MX375469B (me)
MY (1) MY184965A (me)
PE (1) PE20180039A1 (me)
PH (1) PH12017502028A1 (me)
PL (1) PL3294719T3 (me)
PT (1) PT3294719T (me)
RS (1) RS58263B1 (me)
RU (1) RU2713889C2 (me)
SI (1) SI3294719T1 (me)
SM (1) SMT201900053T1 (me)
SV (1) SV2017005560A (me)
TN (1) TN2017000453A1 (me)
TR (1) TR201901228T4 (me)
TW (1) TWI700276B (me)
UA (1) UA120779C2 (me)
WO (1) WO2016180870A1 (me)
ZA (1) ZA201707337B (me)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017288456A1 (en) 2016-07-01 2018-12-13 H. Lundbeck A/S Vortioxetine dosing regimes for fast onset of antidepressant effect
US10519121B2 (en) 2016-12-30 2019-12-31 Apicore Us Llc Process and novel polymorphic form of vortioxetine and its pharmaceutically acceptable salts
EP3582759A4 (en) * 2017-02-17 2021-01-06 Unichem Laboratories Ltd BIOEQUIVALENT PHARMACEUTICAL COMPOSITION OF VORTIOXETINE BROMHYDRATE
PL3532457T3 (pl) * 2017-07-31 2020-10-19 Small Pharma Ltd Postacie krystaliczne hydroksynorketaminy
GB201715950D0 (en) * 2017-10-02 2017-11-15 Croda Int Plc Gel composition comprising a phase change material
WO2020087031A1 (en) 2018-10-26 2020-04-30 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
JP2023520016A (ja) 2020-04-03 2023-05-15 ハー・ルンドベック・アクチエゼルスカベット 感情鈍麻の予防又は処置のための1-[2-(2,4-ジメチルフェニルスルファニル)-フェニル]ピペラジン

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1006728A (en) * 1962-12-31 1965-10-06 Mundipharma Ag Amine salts of pyrrolidone carboxylic acid
JPS6160620A (ja) 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
US4780667A (en) 1985-06-25 1988-10-25 Hewlett-Packard Company Magnetostatic wave delay line discriminator with automatic quadrature setting and automatic calibration
FR2694194B1 (fr) 1992-07-31 1994-11-04 Health Business Dev Gel hydratant, médicament et composition cosmétique le contenant, procédé de préparation dudit gel.
EP0918513B1 (de) 1996-08-15 2000-12-06 Losan Pharma GmbH Gut schluckbare orale arzneiform
US6436946B1 (en) * 1997-05-02 2002-08-20 Morris A. Mann Xanthine-containing compositions for oral administration and uses related thereto
SK284948B6 (sk) 2000-04-06 2006-03-02 Zentiva, A. S. Liečivý prípravok s obsahom vápnika alebo zmesi vápnika a vitamínu D, alebo zmesi vápnika a horčíka v novej liekovej forme
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
DK1758557T3 (da) 2004-05-11 2011-10-24 Egalet Ltd Kvældbar doseringsform omfattende gellangummi
ZA200810017B (en) 2006-06-16 2010-04-28 Lundbeck & Co As H 1- [2- (2, 4-Dimethylphenylsulfanyl) -phenyl] piperazine as a compound with combined serotonin Reuptake, 5-HT3 and 5-HT1A activity for the treatment of cognitive impairment
TW200932233A (en) * 2007-11-13 2009-08-01 Lundbeck & Co As H Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity
JP5722879B2 (ja) 2009-04-24 2015-05-27 ハー・ルンドベック・アクチエゼルスカベット 1−[2−(2,4−ジメチルフェニルスルファニル)フェニル]ピペラジンの塩の液体製剤
KR20120065328A (ko) * 2009-08-24 2012-06-20 하. 룬드벡 아크티에셀스카브 1-[2-(2,4-디메틸-페닐술파닐)-페닐]피페라진의 신규한 조성물
EP2564838A4 (en) * 2010-04-30 2014-06-04 Takeda Pharmaceutical ENTERICIAN TABLET
US9499504B2 (en) 2012-09-19 2016-11-22 Sandoz Ag Crystalline form of vortioxetine hydrobromide
PT2958903T (pt) 2013-02-22 2017-05-26 H Lundbeck As Processo para manufatura de vortioxetina

Also Published As

Publication number Publication date
PH12017502028A1 (en) 2018-04-02
CA2984615A1 (en) 2016-11-17
MA43397A (fr) 2018-03-21
HK1252099B (en) 2020-02-07
AU2016259762B2 (en) 2020-03-19
KR20180006909A (ko) 2018-01-19
US20190210987A1 (en) 2019-07-11
EA201792262A1 (ru) 2018-04-30
SI3294719T1 (sl) 2019-03-29
PT3294719T (pt) 2019-02-07
RU2713889C2 (ru) 2020-02-10
JP6731001B2 (ja) 2020-07-29
DK3294719T3 (en) 2019-02-25
PL3294719T3 (pl) 2019-04-30
MY184965A (en) 2021-04-30
ECSP17074919A (es) 2018-02-28
BR112017024039A2 (pt) 2018-07-24
JP2018515520A (ja) 2018-06-14
CR20170506A (es) 2018-02-08
PE20180039A1 (es) 2018-01-09
US20160368884A1 (en) 2016-12-22
IL255466A (en) 2018-01-31
CA2984615C (en) 2023-06-13
KR102551429B1 (ko) 2023-07-04
GEP20197020B (en) 2019-09-25
TW201706255A (zh) 2017-02-16
ZA201707337B (en) 2019-02-27
CN107567440B (zh) 2021-06-22
SMT201900053T1 (it) 2019-02-28
SV2017005560A (es) 2018-02-23
IL255466B (en) 2022-07-01
GEAP201914622A (en) 2019-05-10
CY1121171T1 (el) 2020-05-29
RU2017139002A (ru) 2019-06-13
CO2017011295A2 (es) 2018-02-20
EA032363B1 (ru) 2019-05-31
RU2017139002A3 (me) 2019-08-30
BR112017024039B1 (pt) 2023-07-04
US11279682B2 (en) 2022-03-22
UA120779C2 (uk) 2020-02-10
JO3456B1 (ar) 2020-07-05
US10287261B2 (en) 2019-05-14
RS58263B1 (sr) 2019-03-29
MX375469B (es) 2025-03-06
CN107567440A (zh) 2018-01-09
HUE042893T2 (hu) 2019-07-29
AR104591A1 (es) 2017-08-02
AU2016259762A1 (en) 2017-11-16
LT3294719T (lt) 2019-02-11
EP3294719A1 (en) 2018-03-21
HRP20190089T1 (hr) 2019-02-22
CL2017002844A1 (es) 2018-05-11
TR201901228T4 (tr) 2019-02-21
EP3294719B1 (en) 2019-01-02
ES2709362T3 (es) 2019-04-16
TN2017000453A1 (en) 2019-04-12
BR112017024039B8 (pt) 2023-10-31
DOP2017000260A (es) 2018-02-28
MX2017014390A (es) 2018-03-23
TWI700276B (zh) 2020-08-01
WO2016180870A1 (en) 2016-11-17
HK1252099A1 (en) 2019-05-17

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