ME00829B - Tečne dermalne formulacije koje stvaraju film za oslobađanje leka na koži - Google Patents
Tečne dermalne formulacije koje stvaraju film za oslobađanje leka na kožiInfo
- Publication number
- ME00829B ME00829B MEP-2009-269A MEP26909A ME00829B ME 00829 B ME00829 B ME 00829B ME P26909 A MEP26909 A ME P26909A ME 00829 B ME00829 B ME 00829B
- Authority
- ME
- Montenegro
- Prior art keywords
- use according
- component
- skin
- solvent
- liquid formulation
- Prior art date
Links
- 239000012669 liquid formulation Substances 0.000 title claims 6
- 230000002500 effect on skin Effects 0.000 title claims 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims 5
- 229920001661 Chitosan Polymers 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 239000002904 solvent Substances 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- -1 antimiotics Substances 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 239000000419 plant extract Substances 0.000 claims 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- OWEGWHBOCFMBLP-UHFFFAOYSA-N 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one Chemical compound C1=CN=CN1C(C(=O)C(C)(C)C)OC1=CC=C(Cl)C=C1 OWEGWHBOCFMBLP-UHFFFAOYSA-N 0.000 claims 1
- KUVIULQEHSCUHY-XYWKZLDCSA-N Beclometasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)COC(=O)CC)(OC(=O)CC)[C@@]1(C)C[C@@H]2O KUVIULQEHSCUHY-XYWKZLDCSA-N 0.000 claims 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 1
- 108010036949 Cyclosporine Proteins 0.000 claims 1
- 208000001840 Dandruff Diseases 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 206010017533 Fungal infection Diseases 0.000 claims 1
- 229940124091 Keratolytic Drugs 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 208000007712 Tinea Versicolor Diseases 0.000 claims 1
- 206010056131 Tinea versicolour Diseases 0.000 claims 1
- OGQICQVSFDPSEI-UHFFFAOYSA-N Zorac Chemical compound N1=CC(C(=O)OCC)=CC=C1C#CC1=CC=C(SCCC2(C)C)C2=C1 OGQICQVSFDPSEI-UHFFFAOYSA-N 0.000 claims 1
- 229960004150 aciclovir Drugs 0.000 claims 1
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 229940030999 antipsoriatics Drugs 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 229940121357 antivirals Drugs 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 229950000210 beclometasone dipropionate Drugs 0.000 claims 1
- LWQQLNNNIPYSNX-UROSTWAQSA-N calcipotriol Chemical compound C1([C@H](O)/C=C/[C@@H](C)[C@@H]2[C@]3(CCCC(/[C@@H]3CC2)=C\C=C\2C([C@@H](O)C[C@H](O)C/2)=C)C)CC1 LWQQLNNNIPYSNX-UROSTWAQSA-N 0.000 claims 1
- 229960002882 calcipotriol Drugs 0.000 claims 1
- 229960003749 ciclopirox Drugs 0.000 claims 1
- SCKYRAXSEDYPSA-UHFFFAOYSA-N ciclopirox Chemical compound ON1C(=O)C=C(C)C=C1C1CCCCC1 SCKYRAXSEDYPSA-UHFFFAOYSA-N 0.000 claims 1
- 229960001265 ciclosporin Drugs 0.000 claims 1
- 229960003344 climbazole Drugs 0.000 claims 1
- 229960002842 clobetasol Drugs 0.000 claims 1
- CBGUOGMQLZIXBE-XGQKBEPLSA-N clobetasol propionate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(OC(=O)CC)[C@@]1(C)C[C@@H]2O CBGUOGMQLZIXBE-XGQKBEPLSA-N 0.000 claims 1
- VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 claims 1
- 229960004022 clotrimazole Drugs 0.000 claims 1
- 239000003246 corticosteroid Substances 0.000 claims 1
- 229960001334 corticosteroids Drugs 0.000 claims 1
- 239000006184 cosolvent Substances 0.000 claims 1
- 229930182912 cyclosporin Natural products 0.000 claims 1
- 239000000824 cytostatic agent Substances 0.000 claims 1
- 230000001085 cytostatic effect Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 238000001704 evaporation Methods 0.000 claims 1
- 208000024386 fungal infectious disease Diseases 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 229940054190 hydroxypropyl chitosan Drugs 0.000 claims 1
- DOUYETYNHWVLEO-UHFFFAOYSA-N imiquimod Chemical compound C1=CC=CC2=C3N(CC(C)C)C=NC3=C(N)N=C21 DOUYETYNHWVLEO-UHFFFAOYSA-N 0.000 claims 1
- 229960002751 imiquimod Drugs 0.000 claims 1
- 229960001438 immunostimulant agent Drugs 0.000 claims 1
- 239000003022 immunostimulating agent Substances 0.000 claims 1
- 230000003308 immunostimulating effect Effects 0.000 claims 1
- 229960003444 immunosuppressant agent Drugs 0.000 claims 1
- 230000001861 immunosuppressant effect Effects 0.000 claims 1
- 239000003018 immunosuppressive agent Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000000077 insect repellent Substances 0.000 claims 1
- 230000001530 keratinolytic effect Effects 0.000 claims 1
- 239000003410 keratolytic agent Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- OIQJEQLSYJSNDS-UHFFFAOYSA-N piroctone Chemical compound CC(C)(C)CC(C)CC1=CC(C)=CC(=O)N1O OIQJEQLSYJSNDS-UHFFFAOYSA-N 0.000 claims 1
- 229950001046 piroctone Drugs 0.000 claims 1
- 201000000508 pityriasis versicolor Diseases 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 229960004889 salicylic acid Drugs 0.000 claims 1
- 210000003625 skull Anatomy 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 238000005507 spraying Methods 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 229960000565 tazarotene Drugs 0.000 claims 1
- 229960002722 terbinafine Drugs 0.000 claims 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims 1
- FUSNMLFNXJSCDI-UHFFFAOYSA-N tolnaftate Chemical compound C=1C=C2C=CC=CC2=CC=1OC(=S)N(C)C1=CC=CC(C)=C1 FUSNMLFNXJSCDI-UHFFFAOYSA-N 0.000 claims 1
- 229960004880 tolnaftate Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Pest Control & Pesticides (AREA)
- Communicable Diseases (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (17)
1. Upotreba: (a) hitozana, derivata hitozana ili njihovih fiziološki prihvatljivih soli, (b) najmanje jednog farmaceutskog ili kozmetički aktivnog sastojka, (e) najmanje jednog isparljivog rastvarača, za proizvodnju tečne kompozicije koja stvara dermalni film posle nanošenja na kožu nakon isparavanja tečnog rastvarača (e).
2.Upotreba prema Zahtevu 1, pri čemu navedena kompozicija distribuira glavne aktivne sastojke na površinu kože.
3.Upotreba prema Zahtevu 1, pri čemu komponenta a) je prisutna u količini od 0.1 do 1O tež. %, u odnosu na ukupnu težinu kompozicije.
4. Upotreba prema Zahtevu 2, pri čemu komponenta a) je prisutna u količini od 0.2 do 5 tež. %, poželjno od 0.25 do 2.0% u odnosu na ukupnu težinu kompozicije.
5.Upotreba prema Zahtevima 1 - 4, pri čemu je komponenta a), derivat hitozana koji je rastvorljiv u vodi ili njegova so
6.Upotreba prema Zahtevima 1 - 5, pri čemu je u vodi rastvorljiv derivat hitozana, hidroksipropil hitozan.
7. Upotreba prema bilo kom od prethodnih zahteva, pri čemu komponenta b) je izabrana od kortikosteroida, imuno-stimulanata, imuno-supresanata, antiviralnih sredstava, citostatika, antimiotika, antibiotika, sredstava protiv psoriaze, keratolitika, retinoida, konzervanasa, sredstava protiv insekata, antioksidanata i biljnih ekstrakata
8. Upotreba prema Zahtevu 7, pri čemu komponenta b) je jedna ili više iz grupe koja uključuje behlometazon dipropionat, klobetazol, pirokton i njegove soli, ciklopiroks i njegove soli, terbinafin i njegove soli, klimbazol, tolnaftat, klotrimazol, ciklosporin, imikvimod, aciklovir, kalcipotriol, tazaroten, salicilnu kiselinu, biljne ekstrakte iz Tarconanthus camphoratus i/ili iz Mela/uca alternifolia.
9. Upotreba prema bilo kom od prethodnih zahteva, pri čemu je komponenta b) prisutna u količini od 0.001 do 15 tež. %, poželjnije od 0.2 do 10 tež. %, najpoželjnije od 0.4 do 5.0 %, u odnosu na ukupnu težinu proizvoda.
10. Upotreba prema bilo kom od prethodnih zahteva, pri čemu je komponenta e), niži alkanol
11. Upotreba prema Zahtevu 10, pri čemu je niži alkanol, etanol ili izopropanol.
12. Upotreba prema Zahtevima 10 i 11, pro čemu je voda, rastvarač ili ko rastvarač.
13. Upotreba prema bilo kom od prethodnih zahteva, pri čemu navedena tečna formulacija uključuje uobičajene ekscipijense i/ili dodatke.
14. Upotreba prema bilo kome od prethodnih zahteva, pri čemu je navedena tečna formulacija pogodna za lečenje stanja i oboljenja kože, kao što je perut, ekcem, atopični dermatitis, psorijaza, mikoze, pityriasis versicolor i druge infekcije.
15. Upotreba prema bilo kom od prethodnih zahteva, pri čemu je navedena tečna formulacija u obliku pogodnom za nanošenje na golu ili kožu sa dlakama, lobanju, spoljne genitalije, ojedene površine i površine između prstiju.
16. Upotreba prema bilo kom od prethodnih zahteva, pri čemu navedena tečna formulacija uključuje rastvore, emulzije i suspenzije.
17. Upotreba prema bilo kom od prethodnih zahteva, pri čemu se navedena tečna formulacija nanosi raspršivanjem.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90140507P | 2007-02-15 | 2007-02-15 | |
| EP07102449A EP1958613A1 (en) | 2007-02-15 | 2007-02-15 | Dermal film-forming liquid formulations for drug release to skin |
| PCT/EP2007/063869 WO2008098634A1 (en) | 2007-02-15 | 2007-12-13 | Dermal film-forming liquid formulations for drug release to skin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ME00829B true ME00829B (me) | 2012-03-20 |
Family
ID=38171596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-2009-269A ME00829B (me) | 2007-02-15 | 2007-12-13 | Tečne dermalne formulacije koje stvaraju film za oslobađanje leka na koži |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20100062083A1 (me) |
| EP (2) | EP1958613A1 (me) |
| JP (1) | JP5376372B2 (me) |
| KR (1) | KR20090119878A (me) |
| CN (2) | CN101641082A (me) |
| AR (1) | AR065318A1 (me) |
| BR (1) | BRPI0721305A2 (me) |
| CA (1) | CA2675568C (me) |
| CL (1) | CL2008000442A1 (me) |
| CO (1) | CO6210803A2 (me) |
| EA (1) | EA019102B1 (me) |
| EC (1) | ECSP099635A (me) |
| IL (2) | IL199841A (me) |
| MA (1) | MA31238B1 (me) |
| ME (1) | ME00829B (me) |
| MX (1) | MX2009008515A (me) |
| MY (1) | MY161895A (me) |
| NO (1) | NO20092998L (me) |
| NZ (1) | NZ578611A (me) |
| UA (1) | UA97134C2 (me) |
| WO (1) | WO2008098634A1 (me) |
| ZA (1) | ZA200904945B (me) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA009031B1 (ru) | 2003-01-24 | 2007-10-26 | Стифел Рисерч Оустрэйлиа Пти Лтд. | Пена на основе фосфата клиндамицина |
| EP2153836A1 (en) * | 2008-08-04 | 2010-02-17 | Polichem S.A. | Film-forming liquid formulations for drug release to hair and scalp |
| EP2116237A1 (en) * | 2008-08-05 | 2009-11-11 | Polichem SA | Compositions for treating rosacea comprising chitosan and a dicarboxylic acid |
| AU2010217190B2 (en) | 2009-02-25 | 2012-10-25 | Mayne Pharma Llc | Topical foam composition |
| CA2760554A1 (en) | 2009-05-01 | 2010-11-04 | Signal Investment And Management Co. | Moisturizing antimicrobial composition |
| WO2011024168A2 (en) * | 2009-08-26 | 2011-03-03 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd | Sustained release delivery systems for the prevention and treatment of head and neck cancers |
| US9364485B2 (en) * | 2009-08-31 | 2016-06-14 | Dr. Reddy's Laboratories Ltd. | Topical formulations comprising a steroid |
| CN106421797A (zh) | 2009-10-01 | 2017-02-22 | 艾戴尔医药公司 | 口服给予的皮质类固醇组合物 |
| GB2477768A (en) * | 2010-02-12 | 2011-08-17 | Chao-Ho Liu | Pharmaceutical material for treating psoriasis |
| NZ610136A (en) * | 2010-11-04 | 2015-06-26 | 442 Ventures Llc | Composition and method for treating skin conditions |
| CN102210746B (zh) * | 2011-04-08 | 2012-11-07 | 福建美菰林生物科技有限公司 | 治疗足部真菌感染的乳膏药物组合物及其制备方法 |
| EP2808030A4 (en) | 2011-11-22 | 2015-06-03 | Univ Dongguk Ind Acad Coop | COMPOSITION FOR THE PREVENTION, TREATMENT OR TREATMENT OF ATOPIC DERMATITIS WITH IMMUNOSUPPRESSIVE AND TRANSGLUTAMINEASE 2 INHIBITOR |
| EP2793833B1 (en) * | 2011-12-20 | 2020-06-24 | Vyome Therapeutics Limited | Topical oil composition for the treatment of fungal infections |
| US8697753B1 (en) * | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
| WO2015034678A2 (en) | 2013-09-06 | 2015-03-12 | Aptalis Pharmatech, Inc. | Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis |
| DK3089737T3 (da) | 2013-12-31 | 2021-12-13 | Rapamycin Holdings Llc | Orale rapamycin-nanopartikelpræparater og anvendelse. |
| CN106551931A (zh) * | 2016-04-11 | 2017-04-05 | 张梦兮 | 1-羟基-2-吡啶酮类化合物在制备口腔黏膜疾病治疗药物上的用途 |
| JP6660258B2 (ja) * | 2016-06-20 | 2020-03-11 | ライオン株式会社 | 制汗剤組成物 |
| TWI777515B (zh) | 2016-08-18 | 2022-09-11 | 美商愛戴爾製藥股份有限公司 | 治療嗜伊紅性食道炎之方法 |
| JP2022127602A (ja) * | 2021-02-19 | 2022-08-31 | アース製薬株式会社 | 噴霧された粒子の収縮を抑制する方法 |
| CN120478204B (zh) * | 2025-06-20 | 2026-02-17 | 诺德溯源(广州)生物科技有限公司 | 一种缓解须后刺激的舒缓修护组合物及应用 |
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| GB1170188A (en) * | 1967-09-15 | 1969-11-12 | Bayer Ag | N-trityl-imidazoles and salts and uses thereof |
| US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
| IL73534A (en) * | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| DE3421363A1 (de) * | 1984-06-08 | 1985-12-12 | Bayer Ag, 5090 Leverkusen | Verfahren und vorrichtung zum kontinuierlichen herstellen von gegenstaenden oder beschichtungen mit kompliziert geformten konturen |
| US4822604A (en) * | 1985-05-20 | 1989-04-18 | S. C. Johnson & Son, Inc. | Local treatment of dandruff, seborrheic dermatitis, and psoriasis |
| DE3541305A1 (de) * | 1985-11-22 | 1987-05-27 | Wella Ag | Kosmetische mittel auf der basis von n-hydroxypropylchitosanen, neue n-hydroxypropyl-chitosane sowie verfahren zu ihrer herstellung |
| US5300494A (en) * | 1986-06-06 | 1994-04-05 | Union Carbide Chemicals & Plastics Technology Corporation | Delivery systems for quaternary and related compounds |
| US4946870A (en) * | 1986-06-06 | 1990-08-07 | Union Carbide Chemicals And Plastics Company Inc. | Delivery systems for pharmaceutical or therapeutic actives |
| AU643058B2 (en) * | 1990-08-30 | 1993-11-04 | Terumo Kabushiki Kaisha | Wound-covering materials |
| JPH0543480A (ja) * | 1991-08-08 | 1993-02-23 | Nippon Soda Co Ltd | 活性ペプタイド含有キトサン誘導体フイルム剤 |
| JPH05339152A (ja) * | 1992-06-09 | 1993-12-21 | Nippon Soda Co Ltd | 皮膚病変局所投与薬剤含有キトサン誘導体フィルム剤 |
| GB9411530D0 (en) * | 1994-06-09 | 1994-08-03 | Quayle Rachel A | Use of polymers as film-forming barrier materials |
| SE9402531L (sv) * | 1994-07-19 | 1996-01-20 | Medicarb Ab | Sårläkningsmedel |
| SE9604610D0 (sv) * | 1996-12-16 | 1996-12-16 | Noviscens Ab | Medical composition |
| US6231875B1 (en) * | 1998-03-31 | 2001-05-15 | Johnson & Johnson Consumer Companies, Inc. | Acidified composition for topical treatment of nail and skin conditions |
| DE10035991A1 (de) * | 2000-07-24 | 2002-02-14 | Polichem Sa | Nagellackzusammensetzung |
| EP1179352A1 (en) * | 2000-08-08 | 2002-02-13 | MONTERESEARCH S.r.l. | Topical composition for covering a skin lesion |
| HUP0501023A3 (en) * | 2001-01-09 | 2008-04-28 | Dvoretzky | Therapeutic film forming composition and treatment system therefor |
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| AU2002950506A0 (en) * | 2002-07-31 | 2002-09-12 | Soltec Research Pty Ltd | Percutaneous delivery system |
| EP1491202A1 (en) * | 2003-06-23 | 2004-12-29 | Polichem S.A. | Nail restructuring compositions for topical application |
| JP2005281654A (ja) * | 2004-03-31 | 2005-10-13 | Rikogaku Shinkokai | 温度応答性組成物およびそのヒドロゲル |
-
2007
- 2007-02-15 EP EP07102449A patent/EP1958613A1/en not_active Withdrawn
- 2007-12-13 CN CN200780051349A patent/CN101641082A/zh active Pending
- 2007-12-13 JP JP2009549363A patent/JP5376372B2/ja not_active Expired - Fee Related
- 2007-12-13 EA EA200901112A patent/EA019102B1/ru not_active IP Right Cessation
- 2007-12-13 MY MYPI20093378A patent/MY161895A/en unknown
- 2007-12-13 ME MEP-2009-269A patent/ME00829B/me unknown
- 2007-12-13 WO PCT/EP2007/063869 patent/WO2008098634A1/en not_active Ceased
- 2007-12-13 EP EP07857516A patent/EP2117500A1/en not_active Withdrawn
- 2007-12-13 CN CN201310643973.2A patent/CN103751790A/zh active Pending
- 2007-12-13 UA UAA200908423A patent/UA97134C2/ru unknown
- 2007-12-13 MX MX2009008515A patent/MX2009008515A/es active IP Right Grant
- 2007-12-13 KR KR1020097018611A patent/KR20090119878A/ko not_active Ceased
- 2007-12-13 US US12/449,571 patent/US20100062083A1/en not_active Abandoned
- 2007-12-13 ZA ZA200904945A patent/ZA200904945B/xx unknown
- 2007-12-13 CA CA2675568A patent/CA2675568C/en not_active Expired - Fee Related
- 2007-12-13 BR BRPI0721305-0A patent/BRPI0721305A2/pt not_active IP Right Cessation
- 2007-12-13 NZ NZ578611A patent/NZ578611A/xx not_active IP Right Cessation
-
2008
- 2008-02-12 CL CL200800442A patent/CL2008000442A1/es unknown
- 2008-02-12 AR ARP080100604A patent/AR065318A1/es unknown
-
2009
- 2009-07-13 IL IL199841A patent/IL199841A/en not_active IP Right Cessation
- 2009-08-14 CO CO09085578A patent/CO6210803A2/es not_active Application Discontinuation
- 2009-09-04 MA MA32202A patent/MA31238B1/fr unknown
- 2009-09-14 NO NO20092998A patent/NO20092998L/no not_active Application Discontinuation
- 2009-09-15 EC EC2009009635A patent/ECSP099635A/es unknown
-
2015
- 2015-09-03 IL IL241166A patent/IL241166A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL199841A0 (en) | 2010-04-15 |
| JP5376372B2 (ja) | 2013-12-25 |
| CO6210803A2 (es) | 2010-10-20 |
| NZ578611A (en) | 2012-08-31 |
| WO2008098634A1 (en) | 2008-08-21 |
| US20100062083A1 (en) | 2010-03-11 |
| CN101641082A (zh) | 2010-02-03 |
| EA200901112A1 (ru) | 2010-02-26 |
| IL241166A0 (en) | 2015-11-30 |
| AR065318A1 (es) | 2009-05-27 |
| EP2117500A1 (en) | 2009-11-18 |
| CN103751790A (zh) | 2014-04-30 |
| IL199841A (en) | 2015-09-24 |
| CL2008000442A1 (es) | 2008-08-22 |
| CA2675568A1 (en) | 2008-08-21 |
| AU2007346756A1 (en) | 2008-08-21 |
| KR20090119878A (ko) | 2009-11-20 |
| NO20092998L (no) | 2009-09-14 |
| AU2007346756A2 (en) | 2009-09-24 |
| MX2009008515A (es) | 2009-08-20 |
| CA2675568C (en) | 2015-05-12 |
| ZA200904945B (en) | 2010-09-29 |
| EA019102B1 (ru) | 2014-01-30 |
| EP1958613A1 (en) | 2008-08-20 |
| MA31238B1 (fr) | 2010-03-01 |
| UA97134C2 (ru) | 2012-01-10 |
| ECSP099635A (es) | 2010-03-31 |
| MY161895A (en) | 2017-05-15 |
| BRPI0721305A2 (pt) | 2014-03-25 |
| JP2010518130A (ja) | 2010-05-27 |
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