MD950443A - Compozitii retinoide stabile cu actiune locala - Google Patents

Compozitii retinoide stabile cu actiune locala

Info

Publication number
MD950443A
MD950443A MD95-0443A MD950443A MD950443A MD 950443 A MD950443 A MD 950443A MD 950443 A MD950443 A MD 950443A MD 950443 A MD950443 A MD 950443A
Authority
MD
Moldova
Prior art keywords
pct
retinoid
sec
ionic surfactant
date
Prior art date
Application number
MD95-0443A
Other languages
English (en)
Other versions
MD1587C2 (ro
MD1587B2 (ro
Inventor
Vringer Tom De
Harrewiin Antoon Van
Aart Muehlenbruch
Original Assignee
Yamanouchi Europ Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD950443(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europ Bv filed Critical Yamanouchi Europ Bv
Publication of MD950443A publication Critical patent/MD950443A/ro
Publication of MD1587B2 publication Critical patent/MD1587B2/ro
Publication of MD1587C2 publication Critical patent/MD1587C2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MD95-0443A 1993-07-01 1994-07-01 Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile MD1587C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
PCT/NL1994/000151 WO1995001160A1 (en) 1993-07-01 1994-07-01 Stable topical retinoid compositions

Publications (3)

Publication Number Publication Date
MD950443A true MD950443A (ro) 1997-09-30
MD1587B2 MD1587B2 (ro) 2001-01-31
MD1587C2 MD1587C2 (ro) 2001-06-30

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0443A MD1587C2 (ro) 1993-07-01 1994-07-01 Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile

Country Status (23)

Country Link
US (1) US5690923A (ro)
EP (1) EP0706370B2 (ro)
JP (2) JP3947215B2 (ro)
AT (1) ATE202694T1 (ro)
AU (1) AU678039B2 (ro)
BG (1) BG61713B1 (ro)
CA (1) CA2166062C (ro)
CZ (1) CZ285679B6 (ro)
DE (1) DE69427639T3 (ro)
DK (1) DK0706370T4 (ro)
ES (1) ES2160631T5 (ro)
FI (1) FI115607B (ro)
GR (1) GR3036761T3 (ro)
HU (1) HU217869B (ro)
MD (1) MD1587C2 (ro)
NO (1) NO311066B1 (ro)
PT (1) PT706370E (ro)
RO (1) RO115109B1 (ro)
RU (1) RU2134101C1 (ro)
SI (1) SI0706370T2 (ro)
SK (1) SK279919B6 (ro)
UA (1) UA41937C2 (ro)
WO (1) WO1995001160A1 (ro)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2134101C1 (ru) * 1993-07-01 1999-08-10 Яманаухи Эуропе Б.В. Стабильные местнодействующие ретиноидные композиции
EP0974364A4 (en) * 1996-10-25 2000-12-20 Yoshitomi Pharmaceutical METHOD FOR PREVENTING THE PREPARATION OF MEDICINAL PRODUCTS
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
KR20020046281A (ko) 1999-08-20 2002-06-20 알 브이 테이트 (로드니 비버스 테이트), 에이치 드로이. 씨. 지. 오닌크, 이. 에디, 산드라 웨드워즈 (에스 제이 에드워즈) 약한 카르복실산으로부터의 피부 자극을 감소시키는 피부화장품 조성물
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
US7141237B2 (en) * 2003-01-24 2006-11-28 Connetics Australia Pty Ltd. Pharmaceutical foam
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
BRPI0517684A (pt) * 2004-11-09 2008-10-14 Imaginative Res Associates Inc soluções de retinóide e formulações feitas a partir das mesmas
EP1814560A2 (en) * 2004-11-19 2007-08-08 Aventis Pharmaceuticals, Inc. Antibiotic compounds, compositions and medical uses
US20060222712A1 (en) * 2005-02-17 2006-10-05 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
WO2007092312A2 (en) * 2006-02-03 2007-08-16 Stiefel Laboratories, Inc. Topical skin treating compositions
NZ571818A (en) * 2006-03-08 2011-10-28 Nihon Nohyaku Co Ltd External pharmaceutical composition comprising luliconazole and an alpha-hydroxycarboxylic acid such as lactic acid, glycolic acid or malic acid.
WO2007102242A1 (ja) * 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物
AU2007273935B2 (en) 2006-03-31 2011-08-18 Stiefel Research Australia Pty Ltd Foamable suspension gel
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
CA2690868A1 (en) * 2007-06-21 2008-12-24 Susan L. Jordan Stabilizers for hydrophobic components in personal care compositions
WO2009031642A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 医薬組成物
EP2191827B1 (en) 2007-09-05 2013-10-30 Pola Pharma Inc. Antifungal composition
KR20100068271A (ko) * 2007-09-05 2010-06-22 가부시키가이샤 폴라 파마 항진균 의약 조성물
WO2009051839A1 (en) * 2007-10-18 2009-04-23 Medicis Pharmaceutical Corporation Aqueous retinoid and benzoyl peroxide gel
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
CN102387786B (zh) * 2009-04-09 2015-09-09 宝丽制药股份有限公司 抗真菌药物组合物
JP5688405B2 (ja) 2009-04-09 2015-03-25 株式会社ポーラファルマ 抗真菌医薬組成物
US8952044B2 (en) 2009-08-25 2015-02-10 Pola Pharma Inc. Antimycotic pharmaceutical composition
US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
EP3698778B1 (en) 2011-06-29 2021-10-13 Sol-Gel Technologies Ltd. Stabilized topical formulations containing core-shell microcapsules
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4532133A (en) * 1983-05-24 1985-07-30 Basf Wyandotte Corporation Low temperature stable, emulsifiable vitamin A concentrates
FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
GB8821129D0 (en) † 1988-09-09 1988-10-12 Unilever Plc Cosmetic composition
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
DE69029804T2 (de) * 1989-06-07 1997-09-04 Gail S Bazzano VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL
JP2827295B2 (ja) * 1989-07-04 1998-11-25 大正製薬株式会社 ビタミンａ類含有点眼剤
FI903483A0 (fi) * 1989-07-13 1990-07-10 Bristol Myers Squibb Co Tretinoin innehaollande stabila emulsionskraemformulationer.
US5043356A (en) * 1990-01-19 1991-08-27 Fulton Jr James E Composition and method for rejuvenating skin using vitamin A propionate
JP3031990B2 (ja) * 1990-10-19 2000-04-10 同仁医薬化工株式会社 消炎鎮痛クリーム剤組成物
RU2134101C1 (ru) * 1993-07-01 1999-08-10 Яманаухи Эуропе Б.В. Стабильные местнодействующие ретиноидные композиции

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia

Also Published As

Publication number Publication date
DK0706370T4 (da) 2005-04-18
ES2160631T5 (es) 2005-07-16
AU678039B2 (en) 1997-05-15
BG100267A (bg) 1996-07-31
JPH08512049A (ja) 1996-12-17
NO311066B1 (no) 2001-10-08
CZ285679B6 (cs) 1999-10-13
BG61713B1 (bg) 1998-04-30
WO1995001160A1 (en) 1995-01-12
ES2160631T3 (es) 2001-11-16
SK159795A3 (en) 1997-03-05
FI956204A (fi) 1995-12-22
HU217869B (hu) 2000-04-28
SI0706370T1 (en) 2001-12-31
ATE202694T1 (de) 2001-07-15
US5690923A (en) 1997-11-25
FI956204A0 (fi) 1995-12-22
EP0706370B1 (en) 2001-07-04
JP3947215B2 (ja) 2007-07-18
HU9503721D0 (en) 1996-02-28
JP2006328089A (ja) 2006-12-07
FI115607B (fi) 2005-06-15
DE69427639T2 (de) 2001-10-18
NO955193L (no) 1996-02-08
CA2166062C (en) 2008-09-16
RU2134101C1 (ru) 1999-08-10
RO115109B1 (ro) 1999-11-30
CZ348395A3 (en) 1996-04-17
MD1587C2 (ro) 2001-06-30
DE69427639T3 (de) 2005-08-04
DK0706370T3 (da) 2001-09-17
UA41937C2 (uk) 2001-10-15
AU7391394A (en) 1995-01-24
SI0706370T2 (en) 2005-06-30
SK279919B6 (sk) 1999-05-07
EP0706370B2 (en) 2005-01-26
PT706370E (pt) 2001-11-30
GR3036761T3 (en) 2001-12-31
NO955193D0 (no) 1995-12-20
HUT74072A (en) 1996-10-28
MD1587B2 (ro) 2001-01-31
EP0706370A1 (en) 1996-04-17
DE69427639D1 (de) 2001-08-09
CA2166062A1 (en) 1995-01-12

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Legal Events

Date Code Title Description
PD99 Pending application
TC4A Change of name of proprietor (patent for invention)

Owner name: ASTELLAS PHARMA EUROPE B.V., NL

Free format text: FORMER OWNER: YAMANOUCHI EUROPE B.V., NL

KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MK4A Patent for invention expired