DE69427639D1 - Retinoid enthaltende stabile topische zusammensetzungen - Google Patents

Retinoid enthaltende stabile topische zusammensetzungen

Info

Publication number
DE69427639D1
DE69427639D1 DE69427639T DE69427639T DE69427639D1 DE 69427639 D1 DE69427639 D1 DE 69427639D1 DE 69427639 T DE69427639 T DE 69427639T DE 69427639 T DE69427639 T DE 69427639T DE 69427639 D1 DE69427639 D1 DE 69427639D1
Authority
DE
Germany
Prior art keywords
pct
retinoid
topical compositions
sec
ionic surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69427639T
Other languages
English (en)
Other versions
DE69427639T3 (de
DE69427639T2 (de
Inventor
Vringer Tom De
Harrewijn Antoon Van
Aart Muehlenbruch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Europe BV
Original Assignee
Yamanouchi Europe BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69427639(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europe BV filed Critical Yamanouchi Europe BV
Publication of DE69427639D1 publication Critical patent/DE69427639D1/de
Application granted granted Critical
Publication of DE69427639T2 publication Critical patent/DE69427639T2/de
Publication of DE69427639T3 publication Critical patent/DE69427639T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69427639T 1993-07-01 1994-07-01 Verwendung von nicht-ionischen oberflächenaktiven substanzen in retinoid enthaltenden stabilen topischen zusammensetzungen Expired - Lifetime DE69427639T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
EP93201931 1993-07-01
PCT/NL1994/000151 WO1995001160A1 (en) 1993-07-01 1994-07-01 Stable topical retinoid compositions

Publications (3)

Publication Number Publication Date
DE69427639D1 true DE69427639D1 (de) 2001-08-09
DE69427639T2 DE69427639T2 (de) 2001-10-18
DE69427639T3 DE69427639T3 (de) 2005-08-04

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427639T Expired - Lifetime DE69427639T3 (de) 1993-07-01 1994-07-01 Verwendung von nicht-ionischen oberflächenaktiven substanzen in retinoid enthaltenden stabilen topischen zusammensetzungen

Country Status (23)

Country Link
US (1) US5690923A (de)
EP (1) EP0706370B2 (de)
JP (2) JP3947215B2 (de)
AT (1) ATE202694T1 (de)
AU (1) AU678039B2 (de)
BG (1) BG61713B1 (de)
CA (1) CA2166062C (de)
CZ (1) CZ285679B6 (de)
DE (1) DE69427639T3 (de)
DK (1) DK0706370T4 (de)
ES (1) ES2160631T5 (de)
FI (1) FI115607B (de)
GR (1) GR3036761T3 (de)
HU (1) HU217869B (de)
MD (1) MD1587C2 (de)
NO (1) NO311066B1 (de)
PT (1) PT706370E (de)
RO (1) RO115109B1 (de)
RU (1) RU2134101C1 (de)
SI (1) SI0706370T2 (de)
SK (1) SK279919B6 (de)
UA (1) UA41937C2 (de)
WO (1) WO1995001160A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0706370T4 (da) * 1993-07-01 2005-04-18 Yamanouchi Europ Bv Anvendelse af nonioniske overfladeaktive stoffer i stabile topiske retinoidsammensætninger
EP0974364A4 (de) * 1996-10-25 2000-12-20 Yoshitomi Pharmaceutical Verfahren zur verhinderung der ausfällung von arzneistoffen
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
KR20020046281A (ko) 1999-08-20 2002-06-20 알 브이 테이트 (로드니 비버스 테이트), 에이치 드로이. 씨. 지. 오닌크, 이. 에디, 산드라 웨드워즈 (에스 제이 에드워즈) 약한 카르복실산으로부터의 피부 자극을 감소시키는 피부화장품 조성물
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
EA014372B1 (ru) * 2003-01-24 2010-10-29 Стифел Рисерч Оустрэйлиа Пти Лтд. Пена на основе фосфата клиндамицина
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
CA2586798A1 (en) 2004-11-09 2006-05-18 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
WO2006055869A2 (en) * 2004-11-19 2006-05-26 Aventis Pharmaceuticals Inc. Antibiotic compounds, compositions and medical uses
WO2006089070A2 (en) * 2005-02-17 2006-08-24 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
WO2007092312A2 (en) * 2006-02-03 2007-08-16 Stiefel Laboratories, Inc. Topical skin treating compositions
EP2025337B1 (de) * 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR ÄUßEREN ANWENDUNG
JP5160409B2 (ja) * 2006-03-08 2013-03-13 日本農薬株式会社 外用の医薬組成物
MX2008012526A (es) 2006-03-31 2008-10-14 Stiefel Res Australia Pyt Ltd Gel espumoso en suspension.
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
EP2170254A2 (de) * 2007-06-21 2010-04-07 Dow Global Technologies Inc. Stabilisierer für hydrophobe komponenten in körperpflegezusammensetzungen
EP2191827B1 (de) 2007-09-05 2013-10-30 Pola Pharma Inc. Antimykotische zusammensetzung
EP2191826B1 (de) 2007-09-05 2017-03-08 Pola Pharma Inc. Pharmazeutische zusammensetzung
EP2191828B1 (de) * 2007-09-05 2016-08-10 Pola Pharma Inc. Antimykotische pharmazeutische zusammensetzung
WO2009051839A1 (en) * 2007-10-18 2009-04-23 Medicis Pharmaceutical Corporation Aqueous retinoid and benzoyl peroxide gel
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
KR101409789B1 (ko) 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
US9050271B2 (en) 2009-04-09 2015-06-09 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2011024620A1 (en) 2009-08-25 2011-03-03 Pola Pharma Inc. Antimycotic pharmaceutical composition
US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4532133A (en) * 1983-05-24 1985-07-30 Basf Wyandotte Corporation Low temperature stable, emulsifiable vitamin A concentrates
FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
GB8821129D0 (en) † 1988-09-09 1988-10-12 Unilever Plc Cosmetic composition
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
US5721275A (en) * 1989-06-07 1998-02-24 Bazzano; Gail S. Slow release vehicles for minimizing skin irritancy of topical compositions
JP2827295B2 (ja) * 1989-07-04 1998-11-25 大正製薬株式会社 ビタミンａ類含有点眼剤
FI903483A0 (fi) * 1989-07-13 1990-07-10 Bristol Myers Squibb Co Tretinoin innehaollande stabila emulsionskraemformulationer.
US5043356A (en) * 1990-01-19 1991-08-27 Fulton Jr James E Composition and method for rejuvenating skin using vitamin A propionate
JP3031990B2 (ja) * 1990-10-19 2000-04-10 同仁医薬化工株式会社 消炎鎮痛クリーム剤組成物
DK0706370T4 (da) * 1993-07-01 2005-04-18 Yamanouchi Europ Bv Anvendelse af nonioniske overfladeaktive stoffer i stabile topiske retinoidsammensætninger

Also Published As

Publication number Publication date
DE69427639T3 (de) 2005-08-04
DK0706370T4 (da) 2005-04-18
NO955193D0 (no) 1995-12-20
EP0706370B1 (de) 2001-07-04
SI0706370T2 (en) 2005-06-30
AU678039B2 (en) 1997-05-15
NO311066B1 (no) 2001-10-08
JPH08512049A (ja) 1996-12-17
FI956204A (fi) 1995-12-22
JP3947215B2 (ja) 2007-07-18
DE69427639T2 (de) 2001-10-18
CZ285679B6 (cs) 1999-10-13
BG100267A (bg) 1996-07-31
FI115607B (fi) 2005-06-15
US5690923A (en) 1997-11-25
SK279919B6 (sk) 1999-05-07
DK0706370T3 (da) 2001-09-17
ATE202694T1 (de) 2001-07-15
HU217869B (hu) 2000-04-28
MD1587B2 (en) 2001-01-31
MD1587C2 (ro) 2001-06-30
ES2160631T5 (es) 2005-07-16
WO1995001160A1 (en) 1995-01-12
RU2134101C1 (ru) 1999-08-10
CZ348395A3 (en) 1996-04-17
EP0706370A1 (de) 1996-04-17
SK159795A3 (en) 1997-03-05
HU9503721D0 (en) 1996-02-28
UA41937C2 (uk) 2001-10-15
SI0706370T1 (en) 2001-12-31
CA2166062A1 (en) 1995-01-12
JP2006328089A (ja) 2006-12-07
NO955193L (no) 1996-02-08
RO115109B1 (ro) 1999-11-30
CA2166062C (en) 2008-09-16
HUT74072A (en) 1996-10-28
ES2160631T3 (es) 2001-11-16
PT706370E (pt) 2001-11-30
AU7391394A (en) 1995-01-24
MD950443A (en) 1997-09-30
FI956204A0 (fi) 1995-12-22
EP0706370B2 (de) 2005-01-26
GR3036761T3 (en) 2001-12-31
BG61713B1 (bg) 1998-04-30

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8327 Change in the person/name/address of the patent owner

Owner name: ASTELLAS PHARMA EUROPE B.V., LEIDERDORP, NL