MD1587C2 - Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile - Google Patents

Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile

Info

Publication number
MD1587C2
MD1587C2 MD95-0443A MD950443A MD1587C2 MD 1587 C2 MD1587 C2 MD 1587C2 MD 950443 A MD950443 A MD 950443A MD 1587 C2 MD1587 C2 MD 1587C2
Authority
MD
Moldova
Prior art keywords
utilization
composition
retinoid
cutaneous application
topical
Prior art date
Application number
MD95-0443A
Other languages
English (en)
Russian (ru)
Other versions
MD1587B2 (ro
MD950443A (ro
Inventor
Tom De Vringer
Antoon VAN HARREWIIN
Aart Muehlenbruch
Original Assignee
Yamanouchi Europe B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD1587(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europe B.V. filed Critical Yamanouchi Europe B.V.
Publication of MD950443A publication Critical patent/MD950443A/ro
Publication of MD1587B2 publication Critical patent/MD1587B2/ro
Publication of MD1587C2 publication Critical patent/MD1587C2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Abstract

Invenţia se referă la compoziţii farmaceutice şi cosmetice apoase cu conţinut deretinoid pentru aplicare topică pe piele.Se revendică compoziţia retinoidă care conţine un vehicul apos, gelifiant, antioxidant, opţional un solvent organic şi o substanţă tensioactivă neionogenă adiţională, selectată din monoesterii polioxietilenici ai unui alcool gras, glicerilesterii polioxietilenici ai unui acid gras, bloc-copolimerii oxidului de etilenă cu oxidul de propilenă. Compoziţia conţine opţional un antibiotic.Totodată se revendică utilizarea compoziţiei în calitate de remediu terapeutic pentru aplicare topică.
MD95-0443A 1993-07-01 1994-07-01 Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile MD1587C2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
PCT/NL1994/000151 WO1995001160A1 (en) 1993-07-01 1994-07-01 Stable topical retinoid compositions

Publications (3)

Publication Number Publication Date
MD950443A MD950443A (ro) 1997-09-30
MD1587B2 MD1587B2 (ro) 2001-01-31
MD1587C2 true MD1587C2 (ro) 2001-06-30

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0443A MD1587C2 (ro) 1993-07-01 1994-07-01 Eteri de 2,6-dihidroxipiridină, procedeu de preparare a lor, compoziţie erbicidă şi metodă de combatere a creşterii plantelor indezirabile

Country Status (23)

Country Link
US (1) US5690923A (ro)
EP (1) EP0706370B2 (ro)
JP (2) JP3947215B2 (ro)
AT (1) ATE202694T1 (ro)
AU (1) AU678039B2 (ro)
BG (1) BG61713B1 (ro)
CA (1) CA2166062C (ro)
CZ (1) CZ285679B6 (ro)
DE (1) DE69427639T3 (ro)
DK (1) DK0706370T4 (ro)
ES (1) ES2160631T5 (ro)
FI (1) FI115607B (ro)
GR (1) GR3036761T3 (ro)
HU (1) HU217869B (ro)
MD (1) MD1587C2 (ro)
NO (1) NO311066B1 (ro)
PT (1) PT706370E (ro)
RO (1) RO115109B1 (ro)
RU (1) RU2134101C1 (ro)
SI (1) SI0706370T2 (ro)
SK (1) SK279919B6 (ro)
UA (1) UA41937C2 (ro)
WO (1) WO1995001160A1 (ro)

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UA41937C2 (uk) * 1993-07-01 2001-10-15 Яманаухі Еуропе Б.В. Стабільна місцеводіюча ретиноідна композиція
WO1998018492A1 (fr) * 1996-10-25 1998-05-07 Yoshitomi Pharmaceutical Industries Ltd. Procede pour empecher la precipitation de medicaments
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
MXPA02001778A (es) * 1999-08-20 2002-08-12 Unilever Nv Composiciones cosmeticas para la piel para reducir irritacion de la piel a partir de acidos carboxilicos debiles.
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
EP1592420B1 (en) * 2003-01-24 2014-01-01 Stiefel Research Australia Pty Ltd Clindamycin phosphate foam
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
ES2344214T3 (es) 2004-11-09 2010-08-20 Imaginative Research Associates, Inc. Soluciones de retinoides y formulaciones preparadas a partir de estas.
WO2006055869A2 (en) * 2004-11-19 2006-05-26 Aventis Pharmaceuticals Inc. Antibiotic compounds, compositions and medical uses
US20060222712A1 (en) * 2005-02-17 2006-10-05 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
US9107844B2 (en) * 2006-02-03 2015-08-18 Stiefel Laboratories Inc. Topical skin treating compositions
JP5160409B2 (ja) * 2006-03-08 2013-03-13 日本農薬株式会社 外用の医薬組成物
CA2645058C (en) * 2006-03-08 2013-07-30 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
KR101368107B1 (ko) 2006-03-31 2014-03-14 스티펠 리서치 오스트레일리아 피티와이 리미티드 발포성 현탁겔
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
CN101790364B (zh) * 2007-06-21 2013-07-24 陶氏环球技术公司 用于个人护理组合物中的疏水组分的稳定剂
EP2191827B1 (en) 2007-09-05 2013-10-30 Pola Pharma Inc. Antifungal composition
US20100204293A1 (en) * 2007-09-05 2010-08-12 Pola Pharma Inc. Pharmaceutical composition
WO2009031644A1 (ja) * 2007-09-05 2009-03-12 Pola Pharma Inc. 抗真菌医薬組成物
CN101903022A (zh) * 2007-10-18 2010-12-01 梅迪奇斯医药公司 类维生素a和过氧化苯甲酰水凝胶
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
WO2010117091A2 (en) * 2009-04-09 2010-10-14 Pola Pharma Inc. Antimycotic pharmaceutical composition
WO2010117089A2 (en) 2009-04-09 2010-10-14 Pola Pharma Inc. Antimycotic pharmaceutical composition
JP5635075B2 (ja) 2009-08-25 2014-12-03 株式会社ポーラファルマ 抗真菌医薬組成物
US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia

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EP0393904A2 (en) * 1989-04-17 1990-10-24 Maxam, Inc. Moisturising vehicle for topical application of vitamin a acid
WO1990014833A1 (en) * 1989-06-07 1990-12-13 Bazzano Gail S Slow release vehicles for minimizing skin irritancy of topical compositions

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FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
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JP2827295B2 (ja) * 1989-07-04 1998-11-25 大正製薬株式会社 ビタミンａ類含有点眼剤
FI903483A0 (fi) * 1989-07-13 1990-07-10 Bristol Myers Squibb Co Tretinoin innehaollande stabila emulsionskraemformulationer.
US5043356A (en) * 1990-01-19 1991-08-27 Fulton Jr James E Composition and method for rejuvenating skin using vitamin A propionate
JP3031990B2 (ja) * 1990-10-19 2000-04-10 同仁医薬化工株式会社 消炎鎮痛クリーム剤組成物
UA41937C2 (uk) * 1993-07-01 2001-10-15 Яманаухі Еуропе Б.В. Стабільна місцеводіюча ретиноідна композиція

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
EP0393904A2 (en) * 1989-04-17 1990-10-24 Maxam, Inc. Moisturising vehicle for topical application of vitamin a acid
WO1990014833A1 (en) * 1989-06-07 1990-12-13 Bazzano Gail S Slow release vehicles for minimizing skin irritancy of topical compositions

Also Published As

Publication number Publication date
WO1995001160A1 (en) 1995-01-12
HU9503721D0 (en) 1996-02-28
CZ285679B6 (cs) 1999-10-13
ATE202694T1 (de) 2001-07-15
NO955193D0 (no) 1995-12-20
ES2160631T5 (es) 2005-07-16
CZ348395A3 (en) 1996-04-17
HUT74072A (en) 1996-10-28
BG61713B1 (bg) 1998-04-30
MD1587B2 (ro) 2001-01-31
ES2160631T3 (es) 2001-11-16
NO955193L (no) 1996-02-08
RU2134101C1 (ru) 1999-08-10
EP0706370A1 (en) 1996-04-17
HU217869B (hu) 2000-04-28
SK279919B6 (sk) 1999-05-07
SI0706370T2 (en) 2005-06-30
SI0706370T1 (en) 2001-12-31
CA2166062C (en) 2008-09-16
JP3947215B2 (ja) 2007-07-18
SK159795A3 (en) 1997-03-05
US5690923A (en) 1997-11-25
AU7391394A (en) 1995-01-24
DK0706370T3 (da) 2001-09-17
EP0706370B1 (en) 2001-07-04
BG100267A (bg) 1996-07-31
NO311066B1 (no) 2001-10-08
UA41937C2 (uk) 2001-10-15
GR3036761T3 (en) 2001-12-31
DK0706370T4 (da) 2005-04-18
EP0706370B2 (en) 2005-01-26
AU678039B2 (en) 1997-05-15
MD950443A (ro) 1997-09-30
RO115109B1 (ro) 1999-11-30
FI956204A (fi) 1995-12-22
JP2006328089A (ja) 2006-12-07
PT706370E (pt) 2001-11-30
FI115607B (fi) 2005-06-15
DE69427639D1 (de) 2001-08-09
DE69427639T3 (de) 2005-08-04
CA2166062A1 (en) 1995-01-12
FI956204A0 (fi) 1995-12-22
DE69427639T2 (de) 2001-10-18
JPH08512049A (ja) 1996-12-17

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Legal Events

Date Code Title Description
PD99 Pending application
TC4A Change of name of proprietor (patent for invention)

Owner name: ASTELLAS PHARMA EUROPE B.V., NL

Free format text: FORMER OWNER: YAMANOUCHI EUROPE B.V., NL

KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MK4A Patent for invention expired