ES2160631T3 - Composiciones de retinoides para aplicacion topica. - Google Patents

Composiciones de retinoides para aplicacion topica.

Info

Publication number
ES2160631T3
ES2160631T3 ES94923832T ES94923832T ES2160631T3 ES 2160631 T3 ES2160631 T3 ES 2160631T3 ES 94923832 T ES94923832 T ES 94923832T ES 94923832 T ES94923832 T ES 94923832T ES 2160631 T3 ES2160631 T3 ES 2160631T3
Authority
ES
Spain
Prior art keywords
pct
retinoid
topical application
sec
ionic surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94923832T
Other languages
English (en)
Other versions
ES2160631T5 (es
Inventor
Vringer Tom De
Harrewijn Antoon Van
Aart Muehlenbruch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Europe BV
Original Assignee
Yamanouchi Europe BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8213946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2160631(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yamanouchi Europe BV filed Critical Yamanouchi Europe BV
Application granted granted Critical
Publication of ES2160631T3 publication Critical patent/ES2160631T3/es
Publication of ES2160631T5 publication Critical patent/ES2160631T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/90—Block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Abstract

SE PRESENTAN COMPOSICIONES, QUE COMPRENDEN UN RETINOIDE EN UN VEHICULO ACUOSO, Y CONTIENEN AL MENOS UN AGENTE ESTABILIZADOR Y DE PREVENCION DE LA CRISTALIZACION. DICHO AGENTE SE SELECCIONA DEL GRUPO DE SURFACTANTES NO IONICOS.
ES94923832T 1993-07-01 1994-07-01 Utilizacion de agentes tensioactivos no ionicos en composiciones estables de retinoides para aplicacion topica. Expired - Lifetime ES2160631T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93201931 1993-07-01
EP93201931 1993-07-01

Publications (2)

Publication Number Publication Date
ES2160631T3 true ES2160631T3 (es) 2001-11-16
ES2160631T5 ES2160631T5 (es) 2005-07-16

Family

ID=8213946

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94923832T Expired - Lifetime ES2160631T5 (es) 1993-07-01 1994-07-01 Utilizacion de agentes tensioactivos no ionicos en composiciones estables de retinoides para aplicacion topica.

Country Status (23)

Country Link
US (1) US5690923A (es)
EP (1) EP0706370B2 (es)
JP (2) JP3947215B2 (es)
AT (1) ATE202694T1 (es)
AU (1) AU678039B2 (es)
BG (1) BG61713B1 (es)
CA (1) CA2166062C (es)
CZ (1) CZ285679B6 (es)
DE (1) DE69427639T3 (es)
DK (1) DK0706370T4 (es)
ES (1) ES2160631T5 (es)
FI (1) FI115607B (es)
GR (1) GR3036761T3 (es)
HU (1) HU217869B (es)
MD (1) MD1587C2 (es)
NO (1) NO311066B1 (es)
PT (1) PT706370E (es)
RO (1) RO115109B1 (es)
RU (1) RU2134101C1 (es)
SI (1) SI0706370T2 (es)
SK (1) SK279919B6 (es)
UA (1) UA41937C2 (es)
WO (1) WO1995001160A1 (es)

Families Citing this family (37)

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SK279919B6 (sk) * 1993-07-01 1999-05-07 Yamanouchi Europe B.V. Farmaceutický a kozmetický prostriedok na miestne
EP0974364A4 (en) * 1996-10-25 2000-12-20 Yoshitomi Pharmaceutical METHOD FOR PREVENTING THE PREPARATION OF MEDICINAL PRODUCTS
DE19903729A1 (de) * 1999-01-30 2000-08-03 Beiersdorf Ag Verwendung von oberflächenaktiven Citronensäureestern zur Stabilisierung von Retinoiden, synergistische Gemische aus Retinoiden und oberflächenaktiven Substanzen sowie kosmetische und dermatologische Zubereitungen mit einem Gehalt an solchen Gemischen
EP1207845A1 (en) 1999-08-20 2002-05-29 Unilever Plc Skin cosmetic compositions for reducing skin irritation from weak carboxylic acids
DE10025756C2 (de) * 2000-05-25 2003-02-20 Cognis Deutschland Gmbh Lösungsvermittler
US6387383B1 (en) 2000-08-03 2002-05-14 Dow Pharmaceutical Sciences Topical low-viscosity gel composition
US7060732B2 (en) * 2000-12-12 2006-06-13 Imaginative Research Associates, Inc. Antibiotic/benzoyl peroxide dispenser
US20060189552A1 (en) * 2000-12-12 2006-08-24 Mohan Vishnupad Dispenser for dispensing three or more actives
US20110142922A1 (en) * 2002-04-30 2011-06-16 Ferndale Ip, Inc. Stabilized composition and method for dermatological treatment
US20030215493A1 (en) * 2002-04-30 2003-11-20 Patel Pravin M. Composition and method for dermatological treatment
US7939489B2 (en) * 2002-12-23 2011-05-10 Avon Products, Inc. Oil absorbent topical compositions and methods for using same
ES2450133T3 (es) * 2003-01-24 2014-03-24 Stiefel Research Australia Pty Ltd Espuma de fosfato de clindamicina
US20060014834A1 (en) * 2004-05-11 2006-01-19 Mohan Vishnupad Retinoid solutions and formulations made therefrom
US7662855B2 (en) * 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
BRPI0517684A (pt) * 2004-11-09 2008-10-14 Imaginative Res Associates Inc soluções de retinóide e formulações feitas a partir das mesmas
WO2006055869A2 (en) * 2004-11-19 2006-05-26 Aventis Pharmaceuticals Inc. Antibiotic compounds, compositions and medical uses
WO2006089070A2 (en) * 2005-02-17 2006-08-24 Connetics Corporation Acne gel
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
WO2007092312A2 (en) * 2006-02-03 2007-08-16 Stiefel Laboratories, Inc. Topical skin treating compositions
CA2645070C (en) * 2006-03-08 2014-02-04 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
MX2008011433A (es) * 2006-03-08 2008-09-18 Nihon Nohyaku Co Ltd Composicion farmaceutica para uso externo.
EP2206494B1 (en) 2006-03-31 2015-12-02 Stiefel Research Australia Pty Ltd Foamable suspension gel
US20080287373A1 (en) * 2007-05-17 2008-11-20 Popp Karl F Topical skin treating kits
CA2690868A1 (en) * 2007-06-21 2008-12-24 Susan L. Jordan Stabilizers for hydrophobic components in personal care compositions
WO2009031643A1 (ja) 2007-09-05 2009-03-12 Pola Pharma Inc. 抗真菌組成物
KR20100075475A (ko) * 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 의약 조성물
KR20100068271A (ko) * 2007-09-05 2010-06-22 가부시키가이샤 폴라 파마 항진균 의약 조성물
JP2011500687A (ja) * 2007-10-18 2011-01-06 メディシス・ファーマシューティカル・コーポレーション 水性レチノイドおよび過酸化ベンゾイルゲル
FR2939683B1 (fr) * 2008-12-17 2012-04-20 Oreal Composition cosmetique comprenant un polyester sulfonique ramifie et un tensioactif particulier et utilisations en coiffage
KR101409792B1 (ko) * 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
JP5688405B2 (ja) 2009-04-09 2015-03-25 株式会社ポーラファルマ 抗真菌医薬組成物
US8952044B2 (en) 2009-08-25 2015-02-10 Pola Pharma Inc. Antimycotic pharmaceutical composition
US11071878B2 (en) * 2009-12-31 2021-07-27 Sol-Gel Technologies Ltd. Core stabilized microcapsules, method of their preparation and uses thereof
JP5865623B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
JP5865624B2 (ja) * 2011-08-01 2016-02-17 昭和電工株式会社 皮膚外用剤およびその製造方法
FR2991175B1 (fr) * 2012-06-01 2014-12-19 Galderma Res & Dev Compositions pharmaceutiques topiques de type emulsion h/e contenant un retinoide
MD4479C1 (ro) * 2015-02-12 2017-12-31 Валериу НИКУШОР Compoziţie de erbicide şi procedeu de combatere a buruienilor şi ierburilor în culturile de sfeclă de zahăr cu utilizarea acesteia

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FR2591105B1 (fr) * 1985-12-11 1989-03-24 Moet Hennessy Rech Composition pharmaceutique, notamment dermatologique, ou cosmetique, a base de phases lamellaires lipidiques hydratees ou de liposomes contenant un retinoide ou un analogue structural dudit retinoide tel qu'un carotenoide.
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SK279919B6 (sk) * 1993-07-01 1999-05-07 Yamanouchi Europe B.V. Farmaceutický a kozmetický prostriedok na miestne

Also Published As

Publication number Publication date
HUT74072A (en) 1996-10-28
FI956204A (fi) 1995-12-22
UA41937C2 (uk) 2001-10-15
ES2160631T5 (es) 2005-07-16
JP2006328089A (ja) 2006-12-07
BG61713B1 (bg) 1998-04-30
DK0706370T3 (da) 2001-09-17
DE69427639D1 (de) 2001-08-09
HU9503721D0 (en) 1996-02-28
CA2166062A1 (en) 1995-01-12
NO311066B1 (no) 2001-10-08
DE69427639T3 (de) 2005-08-04
RU2134101C1 (ru) 1999-08-10
SI0706370T1 (en) 2001-12-31
JP3947215B2 (ja) 2007-07-18
CA2166062C (en) 2008-09-16
DK0706370T4 (da) 2005-04-18
WO1995001160A1 (en) 1995-01-12
MD1587C2 (ro) 2001-06-30
BG100267A (bg) 1996-07-31
PT706370E (pt) 2001-11-30
ATE202694T1 (de) 2001-07-15
GR3036761T3 (en) 2001-12-31
MD950443A (en) 1997-09-30
DE69427639T2 (de) 2001-10-18
SK159795A3 (en) 1997-03-05
AU7391394A (en) 1995-01-24
NO955193L (no) 1996-02-08
MD1587B2 (en) 2001-01-31
FI115607B (fi) 2005-06-15
SI0706370T2 (en) 2005-06-30
RO115109B1 (ro) 1999-11-30
EP0706370B2 (en) 2005-01-26
US5690923A (en) 1997-11-25
SK279919B6 (sk) 1999-05-07
EP0706370A1 (en) 1996-04-17
HU217869B (hu) 2000-04-28
FI956204A0 (fi) 1995-12-22
AU678039B2 (en) 1997-05-15
JPH08512049A (ja) 1996-12-17
EP0706370B1 (en) 2001-07-04
CZ285679B6 (cs) 1999-10-13
NO955193D0 (no) 1995-12-20
CZ348395A3 (en) 1996-04-17

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