MD872G2 - Шипучая фармацевтическая композиция и препарат на ее основе, способ изготовления препарата - Google Patents

Шипучая фармацевтическая композиция и препарат на ее основе, способ изготовления препарата

Info

Publication number
MD872G2
MD872G2 MD95-0026A MD950026A MD872G2 MD 872 G2 MD872 G2 MD 872G2 MD 950026 A MD950026 A MD 950026A MD 872 G2 MD872 G2 MD 872G2
Authority
MD
Moldova
Prior art keywords
preparation
composition
pharmaceutically acceptable
ibuprofen
preparing
Prior art date
Application number
MD95-0026A
Other languages
English (en)
Romanian (ro)
Other versions
MD872F1 (en
Inventor
Nicole Bru-Magniez
Simon Cordoliani Jean-Francois
Jacques Thauvin Gerard
Pierre Drouin Jehan-Yves
Original Assignee
Laboratoires Upsa, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD872(G2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratoires Upsa, S.A. filed Critical Laboratoires Upsa, S.A.
Publication of MD872F1 publication Critical patent/MD872F1/xx
Publication of MD872G2 publication Critical patent/MD872G2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Изобретение относится к фармацевтической промышленности, в частности, к новой фармацевтической композиции, предназначенной для изготовления шипучих порошков и таблеток, содержащих ибупрофен или одну из его фармацевтически приемлемых солей в качестве титра активного ингредиента.Фармацевтическая композиция содержит эффективное количество ибупрофена или одной из его фармацевтически приемлемых солей в качестве титра активного ингредиента, фармацевтически приемлемую шипучую систему, включающую по меньшей мере один щелочной карбонат и одну органическую кислоту, предпочтительно, в количестве, достаточном для получения рН менее 8.Фармацевтический препарат в виде шипучего порошка или таблетки, содержит фармацевтическую композицию, соединенную, по меньшей мере, с одной целевой добавкой, выбранной из подсластителей, ароматизаторов, красителей, смазочных веществ.Способ изготовления фармацевтического препарата в виде шипучего порошка или таблетки со стабилизированным ибупрофеном заключается в том, что ибупрофен или одну из его фармацевтически приемлемых солей обрабатывают фармацевтически приемлемым антиоксидантом в виде раствора или эмульсии, предпочтительно, методом распыления; предварительно перемешивают составляющие, образующие шипучую систему, предпочтительно, в виде гранул; предварительно перемешивают остальные составляющие фармацевтической формы, предпочтительно, в виде порошка; затем перемешивают продукты, полученные на предыдущих этапах.Техническим результатом является повышение стабильности ибупрофена или одной из его фармацевтически приемлемых солей благодаря его предварительной обработке антиоксидантом.
MD95-0026A 1992-12-09 1994-12-22 Шипучая фармацевтическая композиция и препарат на ее основе, способ изготовления препарата MD872G2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214851A FR2698788B1 (fr) 1992-12-09 1992-12-09 Composition pharmaceutique effervescente contenant de l'ibuprofène et son procédé de préparation.

Publications (2)

Publication Number Publication Date
MD872F1 MD872F1 (en) 1997-11-30
MD872G2 true MD872G2 (ru) 1998-08-31

Family

ID=9436398

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0026A MD872G2 (ru) 1992-12-09 1994-12-22 Шипучая фармацевтическая композиция и препарат на ее основе, способ изготовления препарата

Country Status (26)

Country Link
US (2) US5480652A (ru)
EP (1) EP0673245B1 (ru)
JP (1) JP3579421B2 (ru)
KR (1) KR950702414A (ru)
AT (1) ATE158504T1 (ru)
AU (1) AU679200B2 (ru)
CA (1) CA2150945C (ru)
CZ (1) CZ289304B6 (ru)
DE (1) DE69314186T2 (ru)
DK (1) DK0673245T3 (ru)
EE (1) EE03089B1 (ru)
ES (1) ES2110212T3 (ru)
FI (1) FI111517B (ru)
FR (1) FR2698788B1 (ru)
GE (1) GEP19991686B (ru)
GR (1) GR3025634T3 (ru)
HU (1) HU220632B1 (ru)
LV (1) LV11984B (ru)
MD (1) MD872G2 (ru)
NZ (1) NZ258596A (ru)
RU (1) RU2134577C1 (ru)
SK (1) SK281775B6 (ru)
TJ (1) TJ253B (ru)
TW (1) TW280774B (ru)
UA (1) UA27058C2 (ru)
WO (1) WO1994013279A1 (ru)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19502789A1 (de) * 1995-01-28 1996-08-01 Dirk Krischenowski Arzneimittel
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
DE19606151C2 (de) 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
US6534016B1 (en) 1997-04-30 2003-03-18 Richmond Cohen Additive preparation and method of use thereof
US6225123B1 (en) 1997-04-30 2001-05-01 Becton Dickinson And Company Additive preparation and method of use thereof
GB9721397D0 (en) * 1997-10-09 1997-12-10 Verdugt Bv Anticaking agents
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
DE19814256A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Feste, schnellzerfallende Cetirizin-Formulierungen
DE19814257A1 (de) * 1998-03-31 1999-10-07 Asta Medica Ag Brauseformulierungen
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
DE19962251A1 (de) * 1999-12-22 2001-09-06 Hermes Fabrik Pharm Praeparate Lutschtablette
JP2004506609A (ja) * 2000-05-26 2004-03-04 ノボ　ノルディスク　アクティーゼルスカブ 新たなる医薬組成物及びその調製の為の方法
AU2000249111A1 (en) * 2000-05-30 2001-12-11 Dr. Reddy's Research Foundation New pharmaceutical composition and the process for its preparation
AR029538A1 (es) * 2000-07-06 2003-07-02 Wyeth Corp Composiciones farmaceuticas de agentes estrogenicos
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
AU2003219999A1 (en) 2002-03-06 2003-09-22 Lifizz, Inc. Effervescent compositions comprising bisphosphonates and methods related thereto
DE102006029233A1 (de) * 2006-06-26 2007-12-27 Liedtke, Rainer K., Dr. Formulierungen zur Verbesserung der Verträglichkeit nichtsteroidaler Antiphlogistika
EP1902708A1 (de) * 2006-09-25 2008-03-26 Losan Pharma GmbH Wirkstoff enthaltende stabilisierte feste Arzneimittelformen und Verfahren zu ihrer Herstellung
US8445545B2 (en) * 2008-05-07 2013-05-21 Nicholas DeSica Pharmaceutical composition, method of preparation and methods of treating aches/pains
US9267112B2 (en) 2011-05-10 2016-02-23 The Regents Of The University Of California Adenovirus isolated from Titi Monkeys
US10221218B2 (en) 2011-05-10 2019-03-05 The Regents Of The University Of California Adenovirus isolated from titi monkeys
WO2013116112A1 (en) 2012-02-01 2013-08-08 Kraft Foods Global Brands Llc Low calorie drink tablet
JP5877778B2 (ja) * 2012-05-28 2016-03-08 株式会社ホットアルバム炭酸泉タブレット 錠剤の製造方法及び錠剤
RU2519099C1 (ru) * 2012-11-08 2014-06-10 Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт нефтехимического синтеза им. А.В. Топчиева Российской академии наук (ИНХС РАН) Фармацевтическая композиция
FR3060391A1 (fr) * 2016-12-20 2018-06-22 Promindus Sarl Composition pharmaceutique anti douleur

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228164A2 (en) * 1985-11-15 1987-07-08 The Boots Company PLC Effervescent composition containing ibuprofen
EP0351353A1 (en) * 1988-07-12 1990-01-17 ELAN CORPORATION, Plc Anti-inflammatory pharmaceutical composition with an ibuprofen base, with elimination, in solution, of the bitter taste, burning in the throat and intestinal toxicity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
US5178878A (en) * 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228164A2 (en) * 1985-11-15 1987-07-08 The Boots Company PLC Effervescent composition containing ibuprofen
EP0351353A1 (en) * 1988-07-12 1990-01-17 ELAN CORPORATION, Plc Anti-inflammatory pharmaceutical composition with an ibuprofen base, with elimination, in solution, of the bitter taste, burning in the throat and intestinal toxicity

Also Published As

Publication number Publication date
CZ289304B6 (cs) 2001-12-12
FR2698788B1 (fr) 1995-03-03
JPH08504427A (ja) 1996-05-14
EP0673245B1 (fr) 1997-09-24
TW280774B (ru) 1996-07-11
SK281775B6 (sk) 2001-07-10
FI111517B (fi) 2003-08-15
ES2110212T3 (es) 1998-02-01
DE69314186D1 (de) 1997-10-30
SK72895A3 (en) 1995-11-08
HUT73249A (en) 1996-07-29
RU2134577C1 (ru) 1999-08-20
HU9501671D0 (en) 1995-08-28
LV11984A (lv) 1998-03-20
MD872F1 (en) 1997-11-30
FI945452A0 (fi) 1994-11-21
WO1994013279A1 (fr) 1994-06-23
AU5653694A (en) 1994-07-04
CA2150945C (fr) 2006-11-28
UA27058C2 (ru) 2000-02-28
EP0673245A1 (fr) 1995-09-27
FI945452A (fi) 1995-06-07
FR2698788A1 (fr) 1994-06-10
ATE158504T1 (de) 1997-10-15
US5567437A (en) 1996-10-22
US5480652A (en) 1996-01-02
DK0673245T3 (da) 1998-04-27
EE03089B1 (et) 1998-06-15
GR3025634T3 (en) 1998-03-31
CZ141995A3 (en) 1995-10-18
KR950702414A (ko) 1995-07-29
LV11984B (lv) 1998-05-20
HU220632B1 (hu) 2002-03-28
DE69314186T2 (de) 1998-02-12
TJ253B (en) 2000-05-12
AU679200B2 (en) 1997-06-26
JP3579421B2 (ja) 2004-10-20
GEP19991686B (en) 1999-08-05
CA2150945A1 (fr) 1994-06-23
NZ258596A (en) 1997-01-29

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20141222