MD872G2 - Pharmaceutical effrvescent composition and preparation on the basis of it, method for preparation preparing - Google Patents

Pharmaceutical effrvescent composition and preparation on the basis of it, method for preparation preparing

Info

Publication number
MD872G2
MD872G2 MD95-0026A MD950026A MD872G2 MD 872 G2 MD872 G2 MD 872G2 MD 950026 A MD950026 A MD 950026A MD 872 G2 MD872 G2 MD 872G2
Authority
MD
Moldova
Prior art keywords
preparation
composition
pharmaceutically acceptable
ibuprofen
preparing
Prior art date
Application number
MD95-0026A
Other languages
Romanian (ro)
Russian (ru)
Other versions
MD872F1 (en
Inventor
Nicole Bru-Magniez
Simon Cordoliani Jean-Francois
Jacques Thauvin Gerard
Pierre Drouin Jehan-Yves
Original Assignee
Laboratoires Upsa, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MD872(G2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Laboratoires Upsa, S.A. filed Critical Laboratoires Upsa, S.A.
Publication of MD872F1 publication Critical patent/MD872F1/en
Publication of MD872G2 publication Critical patent/MD872G2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A novel pharmaceutical composition for preparing effervescent tablets or powders containing ibuprofen or a pharmaceutically acceptable salt thereof as the active ingredient. Said composition includes an effective amount of ibuprofen or a pharmaceutically acceptable salt thereof; a pharmaceutically acceptable effervescent system including at least one alkaline carbonate and at least one organic acid, preferably in a sufficient amount to give a pH lower than 8; and at least one pharmaceutically acceptable oxidation inhibitor in a sufficient amount to stabilise the ibuprofen. The composition has remarkable stability whether as a powder or as a tablet.
MD95-0026A 1992-12-09 1994-12-22 Pharmaceutical effrvescent composition and preparation on the basis of it, method for preparation preparing MD872G2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9214851A FR2698788B1 (en) 1992-12-09 1992-12-09 Effervescent pharmaceutical composition containing ibuprofen and process for its preparation.

Publications (2)

Publication Number Publication Date
MD872F1 MD872F1 (en) 1997-11-30
MD872G2 true MD872G2 (en) 1998-08-31

Family

ID=9436398

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0026A MD872G2 (en) 1992-12-09 1994-12-22 Pharmaceutical effrvescent composition and preparation on the basis of it, method for preparation preparing

Country Status (26)

Country Link
US (2) US5480652A (en)
EP (1) EP0673245B1 (en)
JP (1) JP3579421B2 (en)
KR (1) KR950702414A (en)
AT (1) ATE158504T1 (en)
AU (1) AU679200B2 (en)
CA (1) CA2150945C (en)
CZ (1) CZ289304B6 (en)
DE (1) DE69314186T2 (en)
DK (1) DK0673245T3 (en)
EE (1) EE03089B1 (en)
ES (1) ES2110212T3 (en)
FI (1) FI111517B (en)
FR (1) FR2698788B1 (en)
GE (1) GEP19991686B (en)
GR (1) GR3025634T3 (en)
HU (1) HU220632B1 (en)
LV (1) LV11984B (en)
MD (1) MD872G2 (en)
NZ (1) NZ258596A (en)
RU (1) RU2134577C1 (en)
SK (1) SK281775B6 (en)
TJ (1) TJ253B (en)
TW (1) TW280774B (en)
UA (1) UA27058C2 (en)
WO (1) WO1994013279A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19502789A1 (en) * 1995-01-28 1996-08-01 Dirk Krischenowski Medicament contg. analgesic, antacid, and/or vitamin etc.
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
DE19606151C2 (en) 1996-02-20 1999-05-12 Losan Pharma Gmbh Effervescent ibuprofen preparation and process for making the same
US6225123B1 (en) 1997-04-30 2001-05-01 Becton Dickinson And Company Additive preparation and method of use thereof
US6534016B1 (en) 1997-04-30 2003-03-18 Richmond Cohen Additive preparation and method of use thereof
GB9721397D0 (en) * 1997-10-09 1997-12-10 Verdugt Bv Anticaking agents
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
DE19814256A1 (en) * 1998-03-31 1999-10-07 Asta Medica Ag Solid, fast-breaking cetirizine formulations
DE19814257A1 (en) * 1998-03-31 1999-10-07 Asta Medica Ag effervescent formulations
IT1301966B1 (en) 1998-07-30 2000-07-20 Zambon Spa PHARMACEUTICAL COMPOSITIONS WITH ANALGESIC ACTIVITY
DE19962251A1 (en) * 1999-12-22 2001-09-06 Hermes Fabrik Pharm Praeparate Lozenge with thermally neutral dissolution properties containing active substance with exothermic dissolution behavior and compensatory adjuvant with endothermic dissolution behavior
JP2004506609A (en) 2000-05-26 2004-03-04 ノボ　ノルディスク　アクティーゼルスカブ New pharmaceutical composition and method for its preparation
AU2000249111A1 (en) * 2000-05-30 2001-12-11 Dr. Reddy's Research Foundation New pharmaceutical composition and the process for its preparation
AR029538A1 (en) 2000-07-06 2003-07-02 Wyeth Corp PHARMACEUTICAL COMPOSITIONS OF ESTROGEN AGENTS
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
DK1490024T3 (en) 2002-03-06 2012-04-10 Effrx Pharmaceuticals Sa Alendronate-containing shower compositions
DE102006029233A1 (en) * 2006-06-26 2007-12-27 Liedtke, Rainer K., Dr. Formulations to improve the tolerability of non-steroidal anti-inflammatory drugs
EP1902708A1 (en) 2006-09-25 2008-03-26 Losan Pharma GmbH Drug comprising stabilized pharmaceutical solid compositions and processes for their preparation
US8445545B2 (en) * 2008-05-07 2013-05-21 Nicholas DeSica Pharmaceutical composition, method of preparation and methods of treating aches/pains
US9267112B2 (en) 2011-05-10 2016-02-23 The Regents Of The University Of California Adenovirus isolated from Titi Monkeys
US10221218B2 (en) 2011-05-10 2019-03-05 The Regents Of The University Of California Adenovirus isolated from titi monkeys
CN104717893A (en) 2012-02-01 2015-06-17 洲际大品牌有限责任公司 Low calorie drink tablet
JP5877778B2 (en) * 2012-05-28 2016-03-08 株式会社ホットアルバム炭酸泉タブレット Tablet manufacturing method and tablet
RU2519099C1 (en) * 2012-11-08 2014-06-10 Федеральное государственное бюджетное учреждение науки Ордена Трудового Красного Знамени Институт нефтехимического синтеза им. А.В. Топчиева Российской академии наук (ИНХС РАН) Pharmaceutical composition
FR3060391A1 (en) * 2016-12-20 2018-06-22 Promindus Sarl PHARMACEUTICAL COMPOSITION ANTI-PAIN

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228164A2 (en) * 1985-11-15 1987-07-08 The Boots Company PLC Effervescent composition containing ibuprofen
EP0351353A1 (en) * 1988-07-12 1990-01-17 ELAN CORPORATION, Plc Anti-inflammatory pharmaceutical composition with an ibuprofen base, with elimination, in solution, of the bitter taste, burning in the throat and intestinal toxicity

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
US5178878A (en) * 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228164A2 (en) * 1985-11-15 1987-07-08 The Boots Company PLC Effervescent composition containing ibuprofen
EP0351353A1 (en) * 1988-07-12 1990-01-17 ELAN CORPORATION, Plc Anti-inflammatory pharmaceutical composition with an ibuprofen base, with elimination, in solution, of the bitter taste, burning in the throat and intestinal toxicity

Also Published As

Publication number Publication date
TJ253B (en) 2000-05-12
FI945452A (en) 1995-06-07
ATE158504T1 (en) 1997-10-15
FI945452A0 (en) 1994-11-21
US5567437A (en) 1996-10-22
GR3025634T3 (en) 1998-03-31
FR2698788A1 (en) 1994-06-10
WO1994013279A1 (en) 1994-06-23
FI111517B (en) 2003-08-15
SK281775B6 (en) 2001-07-10
DE69314186D1 (en) 1997-10-30
CA2150945A1 (en) 1994-06-23
HUT73249A (en) 1996-07-29
CA2150945C (en) 2006-11-28
US5480652A (en) 1996-01-02
LV11984A (en) 1998-03-20
EE03089B1 (en) 1998-06-15
LV11984B (en) 1998-05-20
NZ258596A (en) 1997-01-29
AU679200B2 (en) 1997-06-26
FR2698788B1 (en) 1995-03-03
HU220632B1 (en) 2002-03-28
DK0673245T3 (en) 1998-04-27
UA27058C2 (en) 2000-02-28
SK72895A3 (en) 1995-11-08
MD872F1 (en) 1997-11-30
JP3579421B2 (en) 2004-10-20
DE69314186T2 (en) 1998-02-12
GEP19991686B (en) 1999-08-05
EP0673245A1 (en) 1995-09-27
CZ289304B6 (en) 2001-12-12
EP0673245B1 (en) 1997-09-24
AU5653694A (en) 1994-07-04
CZ141995A3 (en) 1995-10-18
TW280774B (en) 1996-07-11
RU2134577C1 (en) 1999-08-20
KR950702414A (en) 1995-07-29
JPH08504427A (en) 1996-05-14
ES2110212T3 (en) 1998-02-01
HU9501671D0 (en) 1995-08-28

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20141222