IL107956A0 - Carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them - Google Patents
Carboxylic acid derivatives, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL107956A0 IL107956A0 IL10795693A IL10795693A IL107956A0 IL 107956 A0 IL107956 A0 IL 107956A0 IL 10795693 A IL10795693 A IL 10795693A IL 10795693 A IL10795693 A IL 10795693A IL 107956 A0 IL107956 A0 IL 107956A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- carboxylic acid
- pharmaceutical compositions
- compositions containing
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/38—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4241632A DE4241632A1 (en) | 1992-12-10 | 1992-12-10 | New (aza)aromatic or alicyclic carboxylic acid cpds. - used e.g. for treating thrombosis, inflammation, osteoporosis, cardiac infarct or tumour metastasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL107956A0 true IL107956A0 (en) | 1994-04-12 |
Family
ID=6474905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL10795693A IL107956A0 (en) | 1992-12-10 | 1993-12-09 | Carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0604800A1 (en) |
| JP (1) | JPH06239817A (en) |
| KR (1) | KR940014330A (en) |
| CN (1) | CN1094035A (en) |
| AU (1) | AU5230693A (en) |
| CA (1) | CA2111035A1 (en) |
| CZ (1) | CZ270593A3 (en) |
| DE (1) | DE4241632A1 (en) |
| FI (1) | FI935513A (en) |
| HU (1) | HU9303521D0 (en) |
| IL (1) | IL107956A0 (en) |
| MX (1) | MX9307781A (en) |
| NO (2) | NO934501D0 (en) |
| NZ (1) | NZ250391A (en) |
| PL (1) | PL301396A1 (en) |
| SK (1) | SK128193A3 (en) |
| ZA (1) | ZA939230B (en) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4326344A1 (en) * | 1993-08-05 | 1995-02-09 | Thomae Gmbh Dr K | Carbonamides, pharmaceutical compositions containing these compounds and process for their preparation |
| US5814636A (en) * | 1994-07-15 | 1998-09-29 | Meiji Seika Kabushiki Kaisha | Compounds with platelet aggregation inhibitor activity |
| GB9514160D0 (en) * | 1994-07-25 | 1995-09-13 | Zeneca Ltd | Aromatic compounds |
| GB9417532D0 (en) * | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
| GB9420557D0 (en) * | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
| US6069143A (en) * | 1994-12-20 | 2000-05-30 | Smithkline Beecham Corporation | Fibrinogen receptor antagonists |
| TW434240B (en) * | 1995-06-20 | 2001-05-16 | Zeneca Ltd | Aromatic compounds, preparation thereof and pharmaceutical composition comprising same |
| TW502026B (en) * | 1995-06-20 | 2002-09-11 | Zeneca Ltd | Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates |
| US5834468A (en) | 1995-07-07 | 1998-11-10 | Zeneca Limited | Substituted aryl and heteroaryl compounds as E-type prostaglandin antagonists |
| DE19614204A1 (en) * | 1996-04-10 | 1997-10-16 | Thomae Gmbh Dr K | Carboxylic acid derivatives, medicaments containing these compounds, their use and processes for their preparation |
| US5854245A (en) * | 1996-06-28 | 1998-12-29 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1998037068A1 (en) * | 1997-02-21 | 1998-08-27 | Bristol-Myers Squibb Company | Benzoic acid derivatives and related compounds as antiarrhythmic agents |
| AU2002252053B2 (en) | 2001-02-23 | 2006-09-14 | Merck & Co., Inc. | N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists |
| ATE374766T1 (en) | 2003-01-14 | 2007-10-15 | Arena Pharm Inc | 1,2,3-TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM FOR THE PREVENTION AND TREATMENT OF METABOLISM-RELATED DISEASES SUCH AS DIABETES OR HYPERGLYCEMIA |
| ES2316964T3 (en) * | 2003-02-24 | 2009-04-16 | Arena Pharmaceuticals, Inc. | PHENYL-AND PYRIDYLIPIPEREIDINIA-DERIVATIVES AS MODULATORS OF THE GLUCOSE METABOLISM. |
| US7592360B2 (en) | 2003-06-04 | 2009-09-22 | Merck & Co., Inc. | 3-fluoro-piperidines as NMDA/NR2B antagonists |
| AR045047A1 (en) | 2003-07-11 | 2005-10-12 | Arena Pharm Inc | ARILO AND HETEROARILO DERIVATIVES TRISUSTITUIDOS AS MODULATORS OF METABOLISM AND PROFILAXIS AND TREATMENT OF DISORDERS RELATED TO THEMSELVES |
| KR20070004769A (en) | 2004-02-27 | 2007-01-09 | 암젠 인코포레이션 | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders |
| US7786165B2 (en) | 2004-03-15 | 2010-08-31 | Takeda Pharmaceutical Company Limited | Aminophenylpropanoic acid derivative |
| DOP2006000010A (en) | 2005-01-10 | 2006-07-31 | Arena Pharm Inc | PROCEDURE TO PREPARE AROMATIC ETERES |
| MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| US7465804B2 (en) | 2005-05-20 | 2008-12-16 | Amgen Inc. | Compounds, pharmaceutical compositions and methods for their use in treating metabolic disorders |
| CA2621949A1 (en) | 2005-09-14 | 2007-03-22 | Amgen Inc. | Conformationally constrained 3- (4-hydroxy-phenyl) - substituted-propanoic acids useful for treating metabolic disorders |
| AU2007293028B2 (en) | 2006-09-07 | 2012-05-31 | Amgen Inc. | Heterocyclic GPR40 modulators |
| US7687526B2 (en) | 2006-09-07 | 2010-03-30 | Amgen Inc. | Benzo-fused compounds for use in treating metabolic disorders |
| AU2008241490B2 (en) | 2007-04-16 | 2011-07-21 | Amgen Inc. | Substituted biphenyl phenoxy-, thiophenyl- and aminophenylpropanoic acid GPR40 modulators |
| US8030354B2 (en) | 2007-10-10 | 2011-10-04 | Amgen Inc. | Substituted biphenyl GPR40 modulators |
| JP2011515341A (en) | 2008-03-06 | 2011-05-19 | アムジエン・インコーポレーテツド | Conformationally restricted carboxylic acid derivatives useful for the treatment of metabolic disorders |
| EP2358656B1 (en) | 2008-10-15 | 2014-01-01 | Amgen, Inc | Spirocyclic gpr40 modulators |
| BR112013008100A2 (en) | 2010-09-22 | 2016-08-09 | Arena Pharm Inc | "gpr19 receptor modulators and the treatment of disorders related thereto." |
| TW201329025A (en) | 2011-11-01 | 2013-07-16 | Astex Therapeutics Ltd | Pharmaceutical compounds |
| US11007175B2 (en) | 2015-01-06 | 2021-05-18 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the S1P1 receptor |
| NZ738862A (en) | 2015-06-22 | 2023-12-22 | Arena Pharm Inc | Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders |
| CA3053418A1 (en) | 2017-02-16 | 2018-08-23 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of primary biliary cholangitis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4402975A (en) * | 1980-07-21 | 1983-09-06 | Teijin Limited | Aminocarboxylic acids, amino alcohols, or the derivatives thereof, processes for production thereof, and pharmaceutical uses thereof |
| DE3718638A1 (en) * | 1987-06-04 | 1988-12-22 | Thomae Gmbh Dr K | NEW PHENYLETHANOLAMINE, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF |
| US5039805A (en) * | 1988-12-08 | 1991-08-13 | Hoffmann-La Roche Inc. | Novel benzoic and phenylacetic acid derivatives |
| IL99538A0 (en) * | 1990-09-27 | 1992-08-18 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical compositions containing them |
| DE4035961A1 (en) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | CYCLIC IMINODERIVATES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF |
| DE4102024A1 (en) * | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | BIPHENYL DERIVATIVES, MEDICAMENTS CONTAINING THESE COMPOUNDS, AND METHOD FOR THE PRODUCTION THEREOF |
| DE4127404A1 (en) * | 1991-08-19 | 1993-02-25 | Thomae Gmbh Dr K | CYCLIC IMINODERIVATES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF |
| DE4213919A1 (en) * | 1992-04-28 | 1993-11-04 | Thomae Gmbh Dr K | CYCLIC IMINODERIVATES, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENTS CONTAINING SUCH COMPOUNDS |
| DE4213931A1 (en) * | 1992-04-28 | 1993-11-04 | Thomae Gmbh Dr K | CYCLIC IMINODERIVATES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF |
-
1992
- 1992-12-10 DE DE4241632A patent/DE4241632A1/en not_active Withdrawn
-
1993
- 1993-11-17 SK SK1281-93A patent/SK128193A3/en unknown
- 1993-12-08 CA CA002111035A patent/CA2111035A1/en not_active Abandoned
- 1993-12-08 NZ NZ250391A patent/NZ250391A/en unknown
- 1993-12-08 EP EP93119786A patent/EP0604800A1/en not_active Withdrawn
- 1993-12-09 JP JP5308419A patent/JPH06239817A/en active Pending
- 1993-12-09 KR KR1019930027010A patent/KR940014330A/en not_active Application Discontinuation
- 1993-12-09 FI FI935513A patent/FI935513A/en not_active Application Discontinuation
- 1993-12-09 PL PL93301396A patent/PL301396A1/en unknown
- 1993-12-09 HU HU9303521A patent/HU9303521D0/en unknown
- 1993-12-09 IL IL10795693A patent/IL107956A0/en unknown
- 1993-12-09 NO NO934501D patent/NO934501D0/en unknown
- 1993-12-09 MX MX9307781A patent/MX9307781A/en unknown
- 1993-12-09 ZA ZA939230A patent/ZA939230B/en unknown
- 1993-12-09 NO NO934501A patent/NO934501L/en unknown
- 1993-12-10 CZ CZ932705A patent/CZ270593A3/en unknown
- 1993-12-10 CN CN93120876A patent/CN1094035A/en active Pending
- 1993-12-10 AU AU52306/93A patent/AU5230693A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE4241632A1 (en) | 1994-06-16 |
| EP0604800A1 (en) | 1994-07-06 |
| KR940014330A (en) | 1994-07-18 |
| FI935513A0 (en) | 1993-12-09 |
| MX9307781A (en) | 1994-06-30 |
| NZ250391A (en) | 1996-06-25 |
| NO934501D0 (en) | 1993-12-09 |
| FI935513A (en) | 1994-06-11 |
| PL301396A1 (en) | 1994-07-25 |
| JPH06239817A (en) | 1994-08-30 |
| HU9303521D0 (en) | 1994-04-28 |
| CA2111035A1 (en) | 1994-06-11 |
| SK128193A3 (en) | 1995-02-08 |
| CN1094035A (en) | 1994-10-26 |
| CZ270593A3 (en) | 1994-11-16 |
| NO934501L (en) | 1994-06-13 |
| AU5230693A (en) | 1994-06-23 |
| ZA939230B (en) | 1995-06-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL107956A0 (en) | Carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| IL107221A0 (en) | Carboxylic acid derivatives, pharmaceutical compositions containing them and processes for their preparation | |
| IL104446A0 (en) | Acetic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103746A0 (en) | Acetic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL105035A0 (en) | Substituted pipecolinic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL100899A0 (en) | Beta-amino-alpha-hydroxycarboxylic acid derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same | |
| NZ250762A (en) | Five-membered-heterocyclic carboxylic acid derivatives and pharmaceutical compositions | |
| IL117265A (en) | Benzazepine- benzoxazepine- and benzothiazepine-N-acetic acid derivatives their preparation and pharmaceutical compositions containing them | |
| IL103126A (en) | 5-amino-4-hydroxyhexanoic acid derivatives, process for their preparation and pharmaceutical compositions containing them | |
| IL117193A0 (en) | Poly-pyrrolecarbox-amidenaphthalenic acid derivatives their preparation and pharmaceutical compositions containing them | |
| IL102261A0 (en) | 7-isoindolinyl-quinolone-and-naphthyridonecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL108019A0 (en) | Hydroxyiminoalkylindole-carboxylic acid derivatives their preparation and pharmaceutical compositions containing them | |
| IL105375A0 (en) | Acetic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL115072A0 (en) | Substituted 4-phenyl-6-amino-nicotinic acid derivatives their preparation pharmaceutical compositions containing them and their use | |
| IL103437A0 (en) | Cyclohexaneacetic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL101771A0 (en) | Carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them | |
| IL103293A0 (en) | Substituted imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL104356A0 (en) | Benzofuranyl-and thiophenylmethylthio-alkanecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103292A0 (en) | Cyclic-substituted imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL103058A0 (en) | Bicyclic carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them | |
| IL112936A0 (en) | Quinolone - and - naphthyridone - carboxylic acid derivatives, their preparation and pharmaceutical compositions containing them | |
| IL106472A0 (en) | Hydroxamic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL102264A0 (en) | Dicarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them | |
| IL102362A0 (en) | 4-amino-3-hydroxycarboxylic acid derivatives,their production and pharmaceutical compositions containing them | |
| IL103291A0 (en) | Imidazolyl-propenoic acid derivatives,their preparation and pharmaceutical compositions containing them |