MD3334705T2 - Acizi grași cetilați, sistem de preparare și utilizare a acestora - Google Patents

Acizi grași cetilați, sistem de preparare și utilizare a acestora

Info

Publication number
MD3334705T2
MD3334705T2 MDE20180613T MDE20180613T MD3334705T2 MD 3334705 T2 MD3334705 T2 MD 3334705T2 MD E20180613 T MDE20180613 T MD E20180613T MD E20180613 T MDE20180613 T MD E20180613T MD 3334705 T2 MD3334705 T2 MD 3334705T2
Authority
MD
Moldova
Prior art keywords
composition
inflammatory
present
mixture
fatty acids
Prior art date
Application number
MDE20180613T
Other languages
English (en)
Inventor
Andrea Lacorte
Germano Tarantino
Paolo Bondioli
Original Assignee
Pharmanutra S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmanutra S P A filed Critical Pharmanutra S P A
Publication of MD3334705T2 publication Critical patent/MD3334705T2/ro

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/24—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with monohydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/533—Monocarboxylic acid esters having only one carbon-to-carbon double bond
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/04—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils
    • C11C3/08—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fats or fatty oils with fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Abstract

Prezenta invenţie se referă la un procedeu de preparare a unui amestec de acizi graşi cetilaţi şi la un sistem pentru realizarea procesului menţionat. În plus, prezenta invenţie se referă la o compoziţie cuprinzând, sau, alternativ, constând din, amestecul menţionat de acizi graşi cetilaţi. În sfârşit, prezenta invenţie se referă la compoziţia menţionată pentru utilizare în tratamentul şi/sau prevenţia următoarelor: (i) artrita reumatoidă cu origine inflamatoare sau ne-inflamatoare, în particular osteoartrita; (ii) alte tulburări inflamatorii ale articulaţiilor; (iii) psoriazis, lupus, boli periodontale sau boli cardiovasculare sau cardiace; (iv) toate patologiile osteoarticulare post-traumatice inclusiv traumele sportive; (v) toate patologiile degenerative ale articulaţiilor (artroza, gonartroza, coxartroza, etc.), şi (vi) tulburările inflamatoare-traumatice ale tendoanelor şi muşchilor. Suplimentar, se prevede utilizarea compoziţiei prezentei invenţii în tratamentul şi/sau prevenţia patologiilor şi tulburărilor sus-menţionate (i)-(vi) în asociere cu o terapie de reabilitare. Compoziţia cuprinzând amestecul menţionat este formulată într-o formă farmaceutică pentru uz oral (novel food, supliment sau dispozitiv medical), sub formă de pilulă, pastilă, capsulă, comprimat, granule, pulbere dispersabilă, sirop, soluţie sau soluţie pulverizabilă; pentru utilizare topică sub formă de cremă, unguent, pomadă, gel sau spray pentru utilizare cum ar fi aplicarea pe piele, sau pentru utilizare transdermică sub forma unui plasture.
MDE20180613T 2015-08-14 2016-08-09 Acizi grași cetilați, sistem de preparare și utilizare a acestora MD3334705T2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUB2015A003130A ITUB20153130A1 (it) 2015-08-14 2015-08-14 Acidi grassi cetilati, impianto per la loro preparazione e relativo uso
PCT/IB2016/054788 WO2017029580A1 (en) 2015-08-14 2016-08-09 Cetylated fatty acids, system for the preparation thereof and use thereof

Publications (1)

Publication Number Publication Date
MD3334705T2 true MD3334705T2 (ro) 2022-01-31

Family

ID=55069943

Family Applications (1)

Application Number Title Priority Date Filing Date
MDE20180613T MD3334705T2 (ro) 2015-08-14 2016-08-09 Acizi grași cetilați, sistem de preparare și utilizare a acestora

Country Status (22)

Country Link
US (2) US10597608B2 (ro)
EP (2) EP3334705B1 (ro)
CN (1) CN108137472B (ro)
CA (1) CA2995314C (ro)
CY (1) CY1124710T1 (ro)
DK (1) DK3334705T3 (ro)
ES (1) ES2897903T3 (ro)
HK (1) HK1254896A1 (ro)
HR (1) HRP20211702T1 (ro)
HU (1) HUE056361T2 (ro)
IL (2) IL294422B1 (ro)
IT (1) ITUB20153130A1 (ro)
LT (1) LT3334705T (ro)
MA (1) MA42618B1 (ro)
MD (1) MD3334705T2 (ro)
MY (1) MY182324A (ro)
PL (1) PL3334705T3 (ro)
PT (1) PT3334705T (ro)
RS (1) RS62429B1 (ro)
RU (1) RU2756515C2 (ro)
SI (1) SI3334705T1 (ro)
WO (1) WO2017029580A1 (ro)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT201900007311A1 (it) 2019-05-27 2020-11-27 Alesco Srl Procedimento per la preparazione di una composizione comprendente acidi grassi cetilati
IT201900007329A1 (it) 2019-05-27 2020-11-27 Alesco Srl Composizioni comprendenti acidi grassi cetilati per uso nel trattamento della mucosa gastrica, diabete e alti livelli di glicemia
IT201900007326A1 (it) 2019-05-27 2020-11-27 Alesco Srl Composizioni comprendenti acidi grassi cetilati e loro uso nel trattamento di artriti e stati infiammatori articolari
IT202100030170A1 (it) 2021-11-29 2023-05-29 Pharmanutra S P A Cerotto transdermico, e uso di detto cerotto in un metodo di trattamento di un disturbo, o disordine, o patologia, di un tendine

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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US4049824A (en) * 1976-05-03 1977-09-20 Harry Weldon Diehl Cetyl myristoleate
DE3468433D1 (en) * 1983-05-19 1988-02-11 Asahi Denka Kogyo Kk Reaction method for transesterifying fats and oils
GB2233227A (en) * 1989-06-09 1991-01-09 Paul Eldred Buckenham Zinc compositions for treatment of foot odour
CN1197688A (zh) * 1997-04-29 1998-11-04 德国泰克萨科股份公司 在反应塔中物质的化学反应方法
US5898077A (en) * 1997-10-07 1999-04-27 Matsumoto Yushi-Seiyaku Co., Ltd. Process for preparation of an ester
WO2003018731A1 (en) * 1998-11-23 2003-03-06 Dianne Cadwallader Synthesis of ester linked long chain alkyl moieties
AU775941B2 (en) * 2000-05-12 2004-08-19 Lypanosys Pte Limited Treating irritable bowel syndrome or disease
NZ522434A (en) * 2001-05-11 2005-09-30 Meracol Corp Ltd Treating eczema and/or psoriasis
DE10251984A1 (de) * 2002-11-08 2004-05-19 Cognis Deutschland Gmbh & Co. Kg Verfahren zur Herstellung eines Esters
TWI324592B (en) * 2002-11-28 2010-05-11 Sulzer Chemtech Ag A method for the esterification of a fatty acid
US7612111B2 (en) * 2003-03-20 2009-11-03 Imagenetix, Inc. Esterified fatty acid composition
RU2228745C1 (ru) * 2003-04-16 2004-05-20 Общество С Ограниченной Ответственностью "Научно-Технологическая Фармацевтическая Фирма "Полисан" Адаптогенный лекарственный перепарат для перорального применения
US8815282B1 (en) * 2005-07-15 2014-08-26 Edward C. Leonard Commercial method for production of room temperature-liquid cetyl myristoleate
US7276621B2 (en) * 2005-08-12 2007-10-02 Eastman Chemical Company Production of di-(2-ethylhexyl) terephthalate
EP2205709A1 (de) * 2007-10-30 2010-07-14 Bayer Technology Services GmbH Verfahren zur heterogen katalysierten veresterung von fettsäuren
US8394759B2 (en) * 2008-11-21 2013-03-12 Cymbiotics, Inc. Transdermal delivery of medicaments with combinations of cetylated fatty ester penetrant complexes
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WO2011044381A1 (en) * 2009-10-07 2011-04-14 Inflasoothe, Inc. Pain relief composition, system and method
EP2543364A1 (en) * 2010-10-14 2013-01-09 Deva Holding Anonim Sirketi Formulations of cetyl myristate and/or cetyl palmitate
CN103880656A (zh) * 2012-12-24 2014-06-25 青岛帅王油脂化学有限公司 一种脂肪酸酯化的方法

Also Published As

Publication number Publication date
PL3334705T3 (pl) 2022-01-10
CN108137472B (zh) 2021-08-03
ITUB20153130A1 (it) 2017-02-14
CN108137472A (zh) 2018-06-08
IL294422A (en) 2022-08-01
CA2995314C (en) 2024-01-09
RS62429B1 (sr) 2021-11-30
US20190016991A1 (en) 2019-01-17
MY182324A (en) 2021-01-19
RU2756515C2 (ru) 2021-10-01
EP3334705B1 (en) 2021-09-15
SI3334705T1 (sl) 2021-12-31
MA42618A (fr) 2021-04-07
EP3334705A1 (en) 2018-06-20
EP3943478A1 (en) 2022-01-26
US11186536B2 (en) 2021-11-30
IL257143B (en) 2022-08-01
IL294422B1 (en) 2024-03-01
CY1124710T1 (el) 2022-07-22
CA2995314A1 (en) 2017-02-23
US10597608B2 (en) 2020-03-24
LT3334705T (lt) 2021-12-10
PT3334705T (pt) 2021-11-04
MA42618B1 (fr) 2021-10-29
WO2017029580A1 (en) 2017-02-23
HUE056361T2 (hu) 2022-02-28
DK3334705T3 (da) 2021-11-01
RU2018108294A (ru) 2019-09-16
IL257143A (en) 2018-03-29
HK1254896A1 (zh) 2019-08-02
RU2018108294A3 (ro) 2020-05-18
HRP20211702T1 (hr) 2022-02-04
ES2897903T3 (es) 2022-03-03
US20200181530A1 (en) 2020-06-11

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