MD306C2 - Remediu pentru profilaxia afecţiunilor vasculare, determinate de acţiunea peroxizilor glicoproteinfixaţi - Google Patents
Remediu pentru profilaxia afecţiunilor vasculare, determinate de acţiunea peroxizilor glicoproteinfixaţiInfo
- Publication number
- MD306C2 MD306C2 MD94-0391A MD940391A MD306C2 MD 306 C2 MD306 C2 MD 306C2 MD 940391 A MD940391 A MD 940391A MD 306 C2 MD306 C2 MD 306C2
- Authority
- MD
- Moldova
- Prior art keywords
- vessels
- diseases
- peroxides
- prophylactic
- angiopathical
- Prior art date
Links
- 150000002978 peroxides Chemical class 0.000 title abstract 2
- 230000000069 prophylactic effect Effects 0.000 title abstract 2
- 230000001419 dependent effect Effects 0.000 title 1
- 208000019553 vascular disease Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 206010012426 Dermal cyst Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000005755 formation reaction Methods 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-M glutaminate Chemical compound [O-]C(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-M 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- MGNJVOVHTIAIQY-UHFFFAOYSA-L magnesium;(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl phosphate Chemical compound [Mg+2].CC1=NC=C(COP([O-])([O-])=O)C(C=O)=C1O MGNJVOVHTIAIQY-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4016963A DE4016963A1 (de) | 1990-05-25 | 1990-05-25 | Verwendung von magnesium-pyridoxal-5'-phosphat-glutaminat zur verhinderung von erkrankungen, die sich infolge von gefaessschaeden ergeben |
| SU914895539A RU2041713C1 (ru) | 1990-05-25 | 1991-05-24 | Средство для профилактики сосудистых заболеваний, обусловленных действием гликопротеинсвязанных пероксидов |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD306B1 MD306B1 (ro) | 1995-10-31 |
| MD306C2 true MD306C2 (ro) | 1996-02-29 |
Family
ID=6407228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0391A MD306C2 (ro) | 1990-05-25 | 1994-11-25 | Remediu pentru profilaxia afecţiunilor vasculare, determinate de acţiunea peroxizilor glicoproteinfixaţi |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5372999A (OSRAM) |
| EP (1) | EP0458287B1 (OSRAM) |
| JP (1) | JPH07119174B2 (OSRAM) |
| KR (1) | KR970005180B1 (OSRAM) |
| CN (1) | CN1050750C (OSRAM) |
| AT (1) | ATE142884T1 (OSRAM) |
| AU (1) | AU651108B2 (OSRAM) |
| CA (1) | CA2043228C (OSRAM) |
| CZ (1) | CZ280683B6 (OSRAM) |
| DE (2) | DE4016963A1 (OSRAM) |
| DK (1) | DK0458287T3 (OSRAM) |
| EG (1) | EG19730A (OSRAM) |
| ES (1) | ES2091262T3 (OSRAM) |
| GR (1) | GR3021077T3 (OSRAM) |
| HR (1) | HRP931445B1 (OSRAM) |
| HU (1) | HU219223B (OSRAM) |
| IE (1) | IE76728B1 (OSRAM) |
| IL (1) | IL98156A (OSRAM) |
| IN (1) | IN173057B (OSRAM) |
| LT (1) | LT3335B (OSRAM) |
| LV (1) | LV10046B (OSRAM) |
| MD (1) | MD306C2 (OSRAM) |
| MX (1) | MX171883B (OSRAM) |
| RU (1) | RU2041713C1 (OSRAM) |
| SI (1) | SI9110925A (OSRAM) |
| SK (1) | SK278896B6 (OSRAM) |
| UA (1) | UA26973A1 (OSRAM) |
| ZA (1) | ZA913692B (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19527820A1 (de) * | 1995-07-28 | 1997-01-30 | Leniger Follert Elfriede Prof | Arzneimittel zur Behandlung von Ulcera, insbesondere bei arteriellen und venösen Durchblutungsstörungen der Extremitäten, bei chronisch venöser Insuffizienz und Lymphödem |
| DE19532625C2 (de) * | 1995-09-04 | 2000-04-20 | Steigerwald Arzneimittelwerk | Verfahren zur Herstellung von Magnesium-pyridoxal-5'-phosphat-glutamat und dabei erhaltene Zwischenprodukte |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| DE60023125T2 (de) | 1999-03-08 | 2006-06-22 | University Of Manitoba, Winnipeg | Pyridoxal-analoge zur behandlung von störungen ausgelöst durch einen vitamin b6 mangel |
| CA2376029A1 (en) * | 1999-07-13 | 2001-01-18 | Medicure Inc. | Use of pyridoxin derivatives for the treatment of diabetes and related complications |
| JP2003507418A (ja) * | 1999-08-24 | 2003-02-25 | メディキュア インターナショナル インコーポレイテッド | 心血管疾患とその関連疾患の治療 |
| US7442689B2 (en) * | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| US6605612B2 (en) | 2000-02-29 | 2003-08-12 | Medicure International Inc. | Cardioprotective phosohonates and malonates |
| AU784840B2 (en) | 2000-03-28 | 2006-07-06 | Medicure International Inc. | Treatment of cerebrovascular disease |
| RU2163132C1 (ru) * | 2000-06-01 | 2001-02-20 | Научно-исследовательский центр традиционной фитотерапии | Способ лечения сердечно-сосудистых заболеваний фитопрепаратом и лекарственный сбор для лечения сердечно-сосудистых заболеваний |
| EP1299358B1 (en) | 2000-07-07 | 2007-06-13 | Medicure International Inc. | Pyridoxine and pyridoxal analogues as cardiovascular therapeutics |
| US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
| US6897228B2 (en) * | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| US7459468B2 (en) | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| WO2006050598A1 (en) | 2004-10-28 | 2006-05-18 | Medicure International Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
| KR20100015578A (ko) | 2007-03-14 | 2010-02-12 | 시에라 몰레큘러 코포레이션 | 세포 및/또는 거대분자의 보존 및/또는 안정화를 위한 조성물, 시스템 및 방법 |
| RU2484843C1 (ru) * | 2012-04-03 | 2013-06-20 | Алексей Кириллович Пехтерев | Лекарственный сбор растений для лечения сердечно-сосудистых заболеваний |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE246172C (OSRAM) | ||||
| DE2461742C2 (de) * | 1974-12-28 | 1983-01-27 | Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt | Pyridoxin-5'-phosphorsäureester-Derivate sowie deren Herstellung und diese Verbindungen enthaltende Arzneimittel |
| DE3807895A1 (de) * | 1988-03-10 | 1989-09-21 | Knoll Ag | Erzeugnisse, enthaltend einen calciumantagonisten und einen lipidsenker |
-
1990
- 1990-05-25 DE DE4016963A patent/DE4016963A1/de active Granted
-
1991
- 1991-05-13 IN IN362CA1991 patent/IN173057B/en unknown
- 1991-05-15 ZA ZA913692A patent/ZA913692B/xx unknown
- 1991-05-16 IL IL9815691A patent/IL98156A/en active IP Right Grant
- 1991-05-22 EG EG32091A patent/EG19730A/xx active
- 1991-05-22 ES ES91108217T patent/ES2091262T3/es not_active Expired - Lifetime
- 1991-05-22 DK DK91108217.0T patent/DK0458287T3/da active
- 1991-05-22 KR KR1019910008233A patent/KR970005180B1/ko not_active Expired - Fee Related
- 1991-05-22 DE DE69122170T patent/DE69122170T2/de not_active Expired - Fee Related
- 1991-05-22 EP EP91108217A patent/EP0458287B1/en not_active Expired - Lifetime
- 1991-05-22 AT AT91108217T patent/ATE142884T1/de not_active IP Right Cessation
- 1991-05-23 SI SI9110925A patent/SI9110925A/sl unknown
- 1991-05-24 RU SU914895539A patent/RU2041713C1/ru active
- 1991-05-24 CZ CS911563A patent/CZ280683B6/cs not_active IP Right Cessation
- 1991-05-24 AU AU77301/91A patent/AU651108B2/en not_active Ceased
- 1991-05-24 HU HU756/91A patent/HU219223B/hu not_active IP Right Cessation
- 1991-05-24 CA CA002043228A patent/CA2043228C/en not_active Expired - Fee Related
- 1991-05-24 IE IE178391A patent/IE76728B1/en not_active IP Right Cessation
- 1991-05-24 SK SK1563-91A patent/SK278896B6/sk unknown
- 1991-05-24 JP JP3149739A patent/JPH07119174B2/ja not_active Expired - Lifetime
- 1991-05-24 UA UA4895539A patent/UA26973A1/uk unknown
- 1991-05-24 MX MX025919A patent/MX171883B/es unknown
- 1991-05-25 CN CN91104365A patent/CN1050750C/zh not_active Expired - Fee Related
-
1993
- 1993-04-02 US US08/041,896 patent/US5372999A/en not_active Expired - Fee Related
- 1993-05-14 LV LVP-93-343A patent/LV10046B/en unknown
- 1993-05-31 LT LTIP580A patent/LT3335B/lt not_active IP Right Cessation
- 1993-11-26 HR HRP-925/91A patent/HRP931445B1/xx not_active IP Right Cessation
-
1994
- 1994-11-25 MD MD94-0391A patent/MD306C2/ro active IP Right Grant
-
1996
- 1996-09-19 GR GR960402156T patent/GR3021077T3/el unknown
Non-Patent Citations (1)
| Title |
|---|
| Brevet nr. 0203649, EP, Int. cl. A 61 K 31 /66, 1987. * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20110524 |