MD306C2 - Remedy for prophylactic of vascular diseases dependent on glycoproteinfixed peroxides action - Google Patents
Remedy for prophylactic of vascular diseases dependent on glycoproteinfixed peroxides actionInfo
- Publication number
- MD306C2 MD306C2 MD94-0391A MD940391A MD306C2 MD 306 C2 MD306 C2 MD 306C2 MD 940391 A MD940391 A MD 940391A MD 306 C2 MD306 C2 MD 306C2
- Authority
- MD
- Moldova
- Prior art keywords
- vessels
- diseases
- peroxides
- prophylactic
- angiopathical
- Prior art date
Links
- 150000002978 peroxides Chemical class 0.000 title abstract 2
- 230000000069 prophylactic effect Effects 0.000 title abstract 2
- 230000001419 dependent effect Effects 0.000 title 1
- 208000019553 vascular disease Diseases 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 206010012426 Dermal cyst Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000005755 formation reaction Methods 0.000 abstract 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-M glutaminate Chemical compound [O-]C(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-M 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- MGNJVOVHTIAIQY-UHFFFAOYSA-L magnesium;(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methyl phosphate Chemical compound [Mg+2].CC1=NC=C(COP([O-])([O-])=O)C(C=O)=C1O MGNJVOVHTIAIQY-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention relates to using of magnesium-pyridozal-5'-phosphate-glutaminate for warning diseases, prouoked by fixed perioxides and which driven to damage of vessels. The subject matter of invention represents pharmaceutical ensuring of LDL fixed peroxides for avoid or/and reduce vessels damages especially of forming atheromeas or atherosclerosis formations in arterial vessels, as well as of angiopathical diseases in case of diabetes.The object of the proposed invention, especially, represents and pharmaceutical ensuring of indicated cases in case of absence of diagnosis hyperlipides or hypercholes teramias.The purpose indicated is achieved, according to the invention, using magnesium-pyridoxal-5'-phosphate glutaminate, obtaining medicine preparation, useful for prophylactic of deseases, provoked by vessels domages, especially, according to the invention, are prevented atheromes, as well as of angiopathical diseases at the affected group of persons, including diabetesers, smokers, olders, hypertensive patients and persons assaying stress.Fig,: 5
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4016963A DE4016963A1 (en) | 1990-05-25 | 1990-05-25 | USE OF MAGNESIUM PYRIDOXAL 5'-PHOSPHATE GLUTAMINATE TO PREVENT ILLNESSES ARISING AS A RESULT OF DISSOLUTION |
| SU914895539A RU2041713C1 (en) | 1990-05-25 | 1991-05-24 | Method for preventing vascular diseases induced by action of glykoprotein-bound peroxides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD306B1 MD306B1 (en) | 1995-10-31 |
| MD306C2 true MD306C2 (en) | 1996-02-29 |
Family
ID=6407228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MD94-0391A MD306C2 (en) | 1990-05-25 | 1994-11-25 | Remedy for prophylactic of vascular diseases dependent on glycoproteinfixed peroxides action |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5372999A (en) |
| EP (1) | EP0458287B1 (en) |
| JP (1) | JPH07119174B2 (en) |
| KR (1) | KR970005180B1 (en) |
| CN (1) | CN1050750C (en) |
| AT (1) | ATE142884T1 (en) |
| AU (1) | AU651108B2 (en) |
| CA (1) | CA2043228C (en) |
| CZ (1) | CZ280683B6 (en) |
| DE (2) | DE4016963A1 (en) |
| DK (1) | DK0458287T3 (en) |
| EG (1) | EG19730A (en) |
| ES (1) | ES2091262T3 (en) |
| GR (1) | GR3021077T3 (en) |
| HR (1) | HRP931445B1 (en) |
| HU (1) | HU219223B (en) |
| IE (1) | IE76728B1 (en) |
| IL (1) | IL98156A (en) |
| IN (1) | IN173057B (en) |
| LT (1) | LT3335B (en) |
| LV (1) | LV10046B (en) |
| MD (1) | MD306C2 (en) |
| MX (1) | MX171883B (en) |
| RU (1) | RU2041713C1 (en) |
| SI (1) | SI9110925A (en) |
| SK (1) | SK278896B6 (en) |
| UA (1) | UA26973A1 (en) |
| ZA (1) | ZA913692B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19527820A1 (en) * | 1995-07-28 | 1997-01-30 | Leniger Follert Elfriede Prof | Medicines for the treatment of ulcers, especially in the case of arterial and venous circulatory disorders in the extremities, in chronic venous insufficiency and lymphedema |
| DE19532625C2 (en) * | 1995-09-04 | 2000-04-20 | Steigerwald Arzneimittelwerk | Process for the preparation of magnesium pyridoxal-5'-phosphate glutamate and intermediates obtained thereby |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| JP2002539127A (en) | 1999-03-08 | 2002-11-19 | メディキュア インコーポレーテッド | Pyridoxal analogs for vitamin B-6 disorders |
| US6489345B1 (en) | 1999-07-13 | 2002-12-03 | Medicure, Inc. | Treatment of diabetes and related pathologies |
| EP1872797A3 (en) * | 1999-08-24 | 2008-04-02 | Medicure International Inc. | Treatment of cardiovascular and related pathologies |
| US7442689B2 (en) * | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| ES2240419T3 (en) | 2000-02-29 | 2005-10-16 | Medicure International Inc. | HEART PROTECTIVE PHOSPHONATES. |
| AU784840B2 (en) | 2000-03-28 | 2006-07-06 | Medicure International Inc. | Treatment of cerebrovascular disease |
| RU2163132C1 (en) * | 2000-06-01 | 2001-02-20 | Научно-исследовательский центр традиционной фитотерапии | Method of treatment of patients with cardiovascular diseases with phytopreparation and medicinal species for treatment of patients with cardiovascular diseases |
| WO2002004421A2 (en) | 2000-07-07 | 2002-01-17 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: cardiovascular therapeutics |
| US6897228B2 (en) * | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| US6548519B1 (en) | 2001-07-06 | 2003-04-15 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: novel uses |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| JP2008517956A (en) | 2004-10-28 | 2008-05-29 | メディキュア・インターナショナル・インコーポレーテッド | Dual antiplatelet / anticoagulant pyridoxine analogues |
| US7459468B2 (en) | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| CA2680801A1 (en) | 2007-03-14 | 2008-09-18 | Sierra Molecular Corporation | Compositions, systems, and methods for preservation and/or stabilizationof a cell and/or macromolecule |
| RU2484843C1 (en) * | 2012-04-03 | 2013-06-20 | Алексей Кириллович Пехтерев | Medicinal herbal tea for cardiovascular diseases |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE246172C (en) | ||||
| DE2461742C2 (en) * | 1974-12-28 | 1983-01-27 | Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt | Pyridoxine-5'-phosphoric acid ester derivatives and their preparation and pharmaceuticals containing these compounds |
| DE3807895A1 (en) * | 1988-03-10 | 1989-09-21 | Knoll Ag | PRODUCTS CONTAINING A CALCIUM ANTAGONIST AND A LIPID DOWNER |
-
1990
- 1990-05-25 DE DE4016963A patent/DE4016963A1/en active Granted
-
1991
- 1991-05-13 IN IN362CA1991 patent/IN173057B/en unknown
- 1991-05-15 ZA ZA913692A patent/ZA913692B/en unknown
- 1991-05-16 IL IL9815691A patent/IL98156A/en active IP Right Grant
- 1991-05-22 EG EG32091A patent/EG19730A/en active
- 1991-05-22 DK DK91108217.0T patent/DK0458287T3/en active
- 1991-05-22 DE DE69122170T patent/DE69122170T2/en not_active Expired - Fee Related
- 1991-05-22 ES ES91108217T patent/ES2091262T3/en not_active Expired - Lifetime
- 1991-05-22 KR KR1019910008233A patent/KR970005180B1/en not_active Expired - Fee Related
- 1991-05-22 AT AT91108217T patent/ATE142884T1/en not_active IP Right Cessation
- 1991-05-22 EP EP91108217A patent/EP0458287B1/en not_active Expired - Lifetime
- 1991-05-23 SI SI9110925A patent/SI9110925A/en unknown
- 1991-05-24 SK SK1563-91A patent/SK278896B6/en unknown
- 1991-05-24 HU HU756/91A patent/HU219223B/en not_active IP Right Cessation
- 1991-05-24 RU SU914895539A patent/RU2041713C1/en active
- 1991-05-24 MX MX025919A patent/MX171883B/en unknown
- 1991-05-24 CZ CS911563A patent/CZ280683B6/en not_active IP Right Cessation
- 1991-05-24 JP JP3149739A patent/JPH07119174B2/en not_active Expired - Lifetime
- 1991-05-24 IE IE178391A patent/IE76728B1/en not_active IP Right Cessation
- 1991-05-24 UA UA4895539A patent/UA26973A1/en unknown
- 1991-05-24 AU AU77301/91A patent/AU651108B2/en not_active Ceased
- 1991-05-24 CA CA002043228A patent/CA2043228C/en not_active Expired - Fee Related
- 1991-05-25 CN CN91104365A patent/CN1050750C/en not_active Expired - Fee Related
-
1993
- 1993-04-02 US US08/041,896 patent/US5372999A/en not_active Expired - Fee Related
- 1993-05-14 LV LVP-93-343A patent/LV10046B/en unknown
- 1993-05-31 LT LTIP580A patent/LT3335B/en not_active IP Right Cessation
- 1993-11-26 HR HRP-925/91A patent/HRP931445B1/en not_active IP Right Cessation
-
1994
- 1994-11-25 MD MD94-0391A patent/MD306C2/en active IP Right Grant
-
1996
- 1996-09-19 GR GR960402156T patent/GR3021077T3/en unknown
Non-Patent Citations (1)
| Title |
|---|
| Brevet nr. 0203649, EP, Int. cl. A 61 K 31 /66, 1987. * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| IF99 | Valid patent on 19990615 |
Free format text: EXPIRES: 20110524 |