MD306B1 - Remedy for the prophylaxis of vascular diseases caused by the action of glycoprotein-fixed peroxides - Google Patents

Remedy for the prophylaxis of vascular diseases caused by the action of glycoprotein-fixed peroxides

Info

Publication number
MD306B1
MD306B1 MD940391A MD940391A MD306B1 MD 306 B1 MD306 B1 MD 306B1 MD 940391 A MD940391 A MD 940391A MD 940391 A MD940391 A MD 940391A MD 306 B1 MD306 B1 MD 306B1
Authority
MD
Moldova
Prior art keywords
prophylaxis
peroxides
glycoprotein
remedy
action
Prior art date
Application number
MD940391A
Other languages
Romanian (ro)
Other versions
MD306C2 (en
Inventor
Werner Schneider
Britta Meyer
Erich F Prof Dr Elstner
Original Assignee
Steigerwald Arzneimittelwerk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steigerwald Arzneimittelwerk filed Critical Steigerwald Arzneimittelwerk
Publication of MD306B1 publication Critical patent/MD306B1/en
Publication of MD306C2 publication Critical patent/MD306C2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/32Manganese; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to the use of magnesium-pyridoxal-5'-phosphate-glutaminate to prepare a pharmaceutical suitable for the reduction of LDL-bound peroxides and for the prophylaxis of vascular lesions resulting therefrom in the absence of hypercholesteraemia or hyperlipidaemia.
MD94-0391A 1990-05-25 1994-11-25 Remedy for prophylactic of vascular diseases dependent on glycoproteinfixed peroxides action MD306C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4016963A DE4016963A1 (en) 1990-05-25 1990-05-25 USE OF MAGNESIUM PYRIDOXAL 5'-PHOSPHATE GLUTAMINATE TO PREVENT ILLNESSES ARISING AS A RESULT OF DISSOLUTION
SU914895539A RU2041713C1 (en) 1990-05-25 1991-05-24 Method for preventing vascular diseases induced by action of glykoprotein-bound peroxides

Publications (2)

Publication Number Publication Date
MD306B1 true MD306B1 (en) 1995-10-31
MD306C2 MD306C2 (en) 1996-02-29

Family

ID=6407228

Family Applications (1)

Application Number Title Priority Date Filing Date
MD94-0391A MD306C2 (en) 1990-05-25 1994-11-25 Remedy for prophylactic of vascular diseases dependent on glycoproteinfixed peroxides action

Country Status (28)

Country Link
US (1) US5372999A (en)
EP (1) EP0458287B1 (en)
JP (1) JPH07119174B2 (en)
KR (1) KR970005180B1 (en)
CN (1) CN1050750C (en)
AT (1) ATE142884T1 (en)
AU (1) AU651108B2 (en)
CA (1) CA2043228C (en)
CZ (1) CZ280683B6 (en)
DE (2) DE4016963A1 (en)
DK (1) DK0458287T3 (en)
EG (1) EG19730A (en)
ES (1) ES2091262T3 (en)
GR (1) GR3021077T3 (en)
HR (1) HRP931445B1 (en)
HU (1) HU219223B (en)
IE (1) IE76728B1 (en)
IL (1) IL98156A (en)
IN (1) IN173057B (en)
LT (1) LT3335B (en)
LV (1) LV10046B (en)
MD (1) MD306C2 (en)
MX (1) MX171883B (en)
RU (1) RU2041713C1 (en)
SI (1) SI9110925A (en)
SK (1) SK278896B6 (en)
UA (1) UA26973A1 (en)
ZA (1) ZA913692B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008113017A2 (en) 2007-03-14 2008-09-18 Sierra Molecular Corporation Compositions, systems, and methods for preservation and/or stabilization of a cell and/or macromolecule

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19527820A1 (en) * 1995-07-28 1997-01-30 Leniger Follert Elfriede Prof Medicines for the treatment of ulcers, especially in the case of arterial and venous circulatory disorders in the extremities, in chronic venous insufficiency and lymphedema
DE19532625C2 (en) * 1995-09-04 2000-04-20 Steigerwald Arzneimittelwerk Process for the preparation of magnesium pyridoxal-5'-phosphate glutamate and intermediates obtained thereby
US6043259A (en) * 1998-07-09 2000-03-28 Medicure Inc. Treatment of cardiovascular and related pathologies
CA2366602A1 (en) 1999-03-08 2000-09-14 Medicure Inc. Pyridoxal analogues for vitamin b-6 disorders
WO2001003682A2 (en) * 1999-07-13 2001-01-18 Medicure Inc. Use of pyridoxin derivatives for the treatment of diabetes and related complications
EP1210117A2 (en) * 1999-08-24 2002-06-05 Medicure International Inc. Compositons for the treatment of cardiovascular diseases containing pyridoxal compounds and cardiovascular compounds
US7442689B2 (en) * 2000-02-29 2008-10-28 Medicure International Inc. Cardioprotective phosphonates and malonates
PT1268498E (en) 2000-02-29 2005-07-29 Medicure Int Inc CARDIOPROTECTOR PHOSPHONATES
EP1278526A2 (en) 2000-03-28 2003-01-29 Medicure International Inc. Treatment of cerebrovascular disease
US6897228B2 (en) 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
ATE364595T1 (en) 2000-07-07 2007-07-15 Medicure Int Inc PYRIDOXINE AND PYRIDOXAL ANALOGS AS CARDIOVASCULAR THERAPEUTICS
US6548519B1 (en) 2001-07-06 2003-04-15 Medicure International Inc. Pyridoxine and pyridoxal analogues: novel uses
US20070060549A1 (en) * 2004-08-10 2007-03-15 Friesen Albert D Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US7459468B2 (en) 2004-10-28 2008-12-02 Medicure International, Inc. Aryl sulfonic pyridoxines as antiplatelet agents
WO2006050598A1 (en) 2004-10-28 2006-05-18 Medicure International Inc. Dual antiplatelet/anticoagulant pyridoxine analogs
RU2484843C1 (en) * 2012-04-03 2013-06-20 Алексей Кириллович Пехтерев Medicinal herbal tea for cardiovascular diseases

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE246172C (en)
DE2461742C2 (en) * 1974-12-28 1983-01-27 Steigerwald Arzneimittelwerk Gmbh, 6100 Darmstadt Pyridoxine-5'-phosphoric acid ester derivatives and their preparation and pharmaceuticals containing these compounds
DE3807895A1 (en) * 1988-03-10 1989-09-21 Knoll Ag PRODUCTS CONTAINING A CALCIUM ANTAGONIST AND A LIPID DOWNER

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008113017A2 (en) 2007-03-14 2008-09-18 Sierra Molecular Corporation Compositions, systems, and methods for preservation and/or stabilization of a cell and/or macromolecule

Also Published As

Publication number Publication date
GR3021077T3 (en) 1996-12-31
IE76728B1 (en) 1997-11-05
EG19730A (en) 1996-01-31
EP0458287B1 (en) 1996-09-18
ATE142884T1 (en) 1996-10-15
DE4016963C2 (en) 1992-04-30
DE4016963A1 (en) 1991-11-28
IE911783A1 (en) 1991-12-04
US5372999A (en) 1994-12-13
DE69122170T2 (en) 1997-02-20
EP0458287A2 (en) 1991-11-27
DK0458287T3 (en) 1996-10-07
CN1050750C (en) 2000-03-29
HUT58204A (en) 1992-02-28
JPH04235130A (en) 1992-08-24
LV10046B (en) 1995-02-20
MX171883B (en) 1993-11-22
CA2043228C (en) 1998-07-14
SI9110925A (en) 1998-06-30
ES2091262T3 (en) 1996-11-01
DE69122170D1 (en) 1996-10-24
CN1057391A (en) 1992-01-01
AU651108B2 (en) 1994-07-14
KR970005180B1 (en) 1997-04-14
JPH07119174B2 (en) 1995-12-20
RU2041713C1 (en) 1995-08-20
IL98156A0 (en) 1992-06-21
IN173057B (en) 1994-02-05
ZA913692B (en) 1992-02-26
MD306C2 (en) 1996-02-29
LV10046A (en) 1994-05-10
HU219223B (en) 2001-03-28
SK278896B6 (en) 1998-04-08
UA26973A1 (en) 2000-02-28
CA2043228A1 (en) 1991-11-26
CS156391A3 (en) 1992-02-19
HRP931445B1 (en) 2000-04-30
HU911756D0 (en) 1991-12-30
EP0458287A3 (en) 1992-04-08
CZ280683B6 (en) 1996-04-17
LTIP580A (en) 1994-12-27
HRP931445A2 (en) 1996-02-29
IL98156A (en) 1996-06-18
AU7730191A (en) 1991-11-28
KR910019616A (en) 1991-12-19
LT3335B (en) 1995-07-25

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20110524