MA51139A - Dérivés de 1-(pipéridinocarbonylméthyl)-2-oxopipérazine pour le traitement du cancer - Google Patents
Dérivés de 1-(pipéridinocarbonylméthyl)-2-oxopipérazine pour le traitement du cancerInfo
- Publication number
- MA51139A MA51139A MA051139A MA51139A MA51139A MA 51139 A MA51139 A MA 51139A MA 051139 A MA051139 A MA 051139A MA 51139 A MA51139 A MA 51139A MA 51139 A MA51139 A MA 51139A
- Authority
- MA
- Morocco
- Prior art keywords
- piperidinocarbonylmethyl
- cancer
- treatment
- oxopiperazine derivatives
- oxopiperazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762599336P | 2017-12-15 | 2017-12-15 | |
| CH1522018 | 2018-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA51139A true MA51139A (fr) | 2020-10-21 |
Family
ID=65003562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA051139A MA51139A (fr) | 2017-12-15 | 2018-12-17 | Dérivés de 1-(pipéridinocarbonylméthyl)-2-oxopipérazine pour le traitement du cancer |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10710975B2 (fr) |
| EP (1) | EP3724178B1 (fr) |
| JP (1) | JP7307744B2 (fr) |
| KR (2) | KR20250078596A (fr) |
| CN (1) | CN111788191B (fr) |
| AU (1) | AU2018386327B2 (fr) |
| CA (1) | CA3085481A1 (fr) |
| IL (1) | IL275337B2 (fr) |
| MA (1) | MA51139A (fr) |
| MX (1) | MX2020006219A (fr) |
| RU (1) | RU2020123261A (fr) |
| SG (1) | SG11202005365WA (fr) |
| TW (1) | TWI810229B (fr) |
| WO (1) | WO2019118973A1 (fr) |
| ZA (1) | ZA202003554B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3724178B1 (fr) | 2017-12-15 | 2024-05-01 | Inthera Bioscience AG | Dérivés de 1-(pipéridinocarbonylméthyl)-2-oxopipérazine pour le traitement du cancer |
| AR116020A1 (es) | 2018-09-03 | 2021-03-25 | Bayer Ag | COMPUESTOS DE 3,9-DIAZAESPIRO[5.5]UNDECANO COMO INHIBIDORES DE GGTasa I Y SU USO PARA EL TRATAMIENTO DE ENFERMEDADES HIPERPROLIFERATIVAS |
| WO2020048827A1 (fr) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | Composés de la 1,3,9-triazaspiro[5.5]undécan-2-one |
| WO2020048831A1 (fr) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | Composés 5-aryl-3,9-diazaspiro[5.5]undécan-2-one |
| WO2020048826A1 (fr) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | Composés de la 1-oxa-3,9-diazaspiro[5.5]undécan-2-one substituée en position 5 |
| WO2020048828A1 (fr) | 2018-09-03 | 2020-03-12 | Bayer Pharma Aktiengesellschaft | Composés du 5-hétéroaryl-3,9-diazaspiro[5.5]undécane |
| WO2020048830A1 (fr) | 2018-09-03 | 2020-03-12 | Bayer Aktiengesellschaft | Composés 5-aryl-3,9-diazaspiro[5.5]undécan-2-one |
| WO2021144302A1 (fr) * | 2020-01-13 | 2021-07-22 | Inthera Bioscience AG | Biomarqueurs pour déterminer la sensibilité à des dérivés d'oxopipérazine et leurs méthodes d'utilisation |
| US12611406B2 (en) | 2020-06-19 | 2026-04-28 | Inthera Bioscience AG | Oxopiperazine derivatives for the treatment of cancer |
| US20240122941A1 (en) * | 2020-12-25 | 2024-04-18 | National Cancer Center | Therapy based on synthetic lethality in swi/snf complex-dysfunction cancer |
| CN119948030A (zh) * | 2022-07-15 | 2025-05-06 | 苏特罗生物制药公司 | 蛋白酶/酶可切割连接体-有效载荷及蛋白质偶联物 |
| JP2025532590A (ja) * | 2022-09-16 | 2025-10-01 | シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト | 殺有害生物的に活性な環状アミン化合物 |
| EP4719418A1 (fr) | 2023-05-26 | 2026-04-08 | Inthera Bioscience AG | Dérivés d'oxopipérazine pour le traitement du cancer |
| WO2026090509A1 (fr) * | 2024-10-25 | 2026-04-30 | Architect Therapeutics, Inc. | Inhibiteurs spiro hétérocycliques de cdk2 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5885995A (en) | 1996-04-03 | 1999-03-23 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| DE60234354D1 (de) | 2001-08-24 | 2009-12-24 | Univ Yale | Piperazinon-verbindungen als antitumorale und krebsbekämpfende mittel |
| ES2347643T3 (es) * | 2001-10-17 | 2010-11-03 | Schering Corporation | Piperin- y piperazinacetamidas como inhibidores de 17beta hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades dependientes de androgenos. |
| ES2345146T3 (es) * | 2002-11-18 | 2010-09-16 | Schering Corporation | Inhibidores de 17beta-hidroxiesteroides deshidrogenasa de tipo 3 para el tratamiento de enfermedades dependientes de androgenos. |
| JP2006516632A (ja) | 2003-01-30 | 2006-07-06 | スミスクライン・ビーチャム・コーポレイション | Ｎｋ−２およびｎｋ−３受容体アンタゴニストとしてのキノリン誘導体 |
| GB0314733D0 (en) * | 2003-06-24 | 2003-07-30 | Glaxo Group Ltd | Medicaments |
| WO2007016496A2 (fr) * | 2005-08-02 | 2007-02-08 | Neurogen Corporation | Dipipérazinyl cétones et analogues apparentés |
| CN101341123A (zh) * | 2005-12-21 | 2009-01-07 | 因塞特公司 | 作为趋化因子受体调节剂的3-氨基环戊烷甲酰胺 |
| US8791121B2 (en) | 2010-08-12 | 2014-07-29 | New York University | Oligooxopiperazines and methods of making and using them |
| WO2012143879A1 (fr) * | 2011-04-21 | 2012-10-26 | Piramal Healthcare Limited | Forme cristalline d'un sel d'un dérivé de morpholinosulfonylindole et son procédé de préparation |
| JP6258867B2 (ja) | 2012-01-25 | 2018-01-10 | ノバルティス アーゲー | 複素環式化合物およびその使用方法 |
| WO2013123511A1 (fr) * | 2012-02-16 | 2013-08-22 | New York University | Contrôle de l'expression génique induite par l'hypoxie avec des mimétiques hélicoïdaux non peptidiques d'oligo-oxopipérazine |
| US9695153B2 (en) | 2013-01-19 | 2017-07-04 | New York University | Oligooxopiperazines for p53 reactivation |
| WO2015160914A1 (fr) | 2014-04-15 | 2015-10-22 | New York University | Mimétiques d'hélice oxopipérazine en tant qu'inhibiteurs de l'interaction p53-mdm2 |
| EP3145921A4 (fr) * | 2014-05-21 | 2017-11-08 | New York University | Mimétiques d'hélice d'oxopipérazine pour le contrôle de l'expression génétique inductible par hypoxie |
| EP3724178B1 (fr) | 2017-12-15 | 2024-05-01 | Inthera Bioscience AG | Dérivés de 1-(pipéridinocarbonylméthyl)-2-oxopipérazine pour le traitement du cancer |
| WO2021144302A1 (fr) | 2020-01-13 | 2021-07-22 | Inthera Bioscience AG | Biomarqueurs pour déterminer la sensibilité à des dérivés d'oxopipérazine et leurs méthodes d'utilisation |
| US12611406B2 (en) | 2020-06-19 | 2026-04-28 | Inthera Bioscience AG | Oxopiperazine derivatives for the treatment of cancer |
-
2018
- 2018-12-17 EP EP18830663.3A patent/EP3724178B1/fr active Active
- 2018-12-17 JP JP2020552682A patent/JP7307744B2/ja active Active
- 2018-12-17 RU RU2020123261A patent/RU2020123261A/ru unknown
- 2018-12-17 TW TW107145504A patent/TWI810229B/zh active
- 2018-12-17 SG SG11202005365WA patent/SG11202005365WA/en unknown
- 2018-12-17 IL IL275337A patent/IL275337B2/en unknown
- 2018-12-17 WO PCT/US2018/066027 patent/WO2019118973A1/fr not_active Ceased
- 2018-12-17 US US16/222,479 patent/US10710975B2/en active Active
- 2018-12-17 KR KR1020257016396A patent/KR20250078596A/ko active Pending
- 2018-12-17 MA MA051139A patent/MA51139A/fr unknown
- 2018-12-17 KR KR1020207020485A patent/KR102811956B1/ko active Active
- 2018-12-17 CA CA3085481A patent/CA3085481A1/fr active Pending
- 2018-12-17 MX MX2020006219A patent/MX2020006219A/es unknown
- 2018-12-17 AU AU2018386327A patent/AU2018386327B2/en active Active
- 2018-12-17 CN CN201880089454.7A patent/CN111788191B/zh active Active
-
2020
- 2020-06-03 US US16/891,417 patent/US11306068B2/en active Active
- 2020-06-12 ZA ZA2020/03554A patent/ZA202003554B/en unknown
-
2022
- 2022-01-07 US US17/570,959 patent/US12012393B2/en active Active
-
2024
- 2024-04-30 US US18/650,360 patent/US20250115571A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US10710975B2 (en) | 2020-07-14 |
| WO2019118973A1 (fr) | 2019-06-20 |
| IL275337A (en) | 2020-07-30 |
| AU2018386327A1 (en) | 2020-06-25 |
| US20190185449A1 (en) | 2019-06-20 |
| MX2020006219A (es) | 2020-12-03 |
| KR20200101397A (ko) | 2020-08-27 |
| CA3085481A1 (fr) | 2019-06-20 |
| CN111788191A (zh) | 2020-10-16 |
| KR102811956B1 (ko) | 2025-05-23 |
| ZA202003554B (en) | 2024-11-27 |
| US20200308139A1 (en) | 2020-10-01 |
| US20220213057A1 (en) | 2022-07-07 |
| US11306068B2 (en) | 2022-04-19 |
| KR20250078596A (ko) | 2025-06-02 |
| RU2020123261A (ru) | 2022-01-17 |
| US20250115571A1 (en) | 2025-04-10 |
| CN111788191B (zh) | 2024-06-04 |
| TWI810229B (zh) | 2023-08-01 |
| EP3724178B1 (fr) | 2024-05-01 |
| EP3724178A1 (fr) | 2020-10-21 |
| AU2018386327B2 (en) | 2023-04-13 |
| TW201930286A (zh) | 2019-08-01 |
| US12012393B2 (en) | 2024-06-18 |
| SG11202005365WA (en) | 2020-07-29 |
| JP7307744B2 (ja) | 2023-07-12 |
| IL275337B2 (en) | 2024-06-01 |
| RU2020123261A3 (fr) | 2022-02-16 |
| IL275337B1 (en) | 2024-02-01 |
| JP2021506973A (ja) | 2021-02-22 |
| BR112020011925A2 (pt) | 2020-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA43746A (fr) | Dérivés de 2-cyanoisoindoline pour le traitement du cancer | |
| MA49144A (fr) | Polythérapies pour le traitement du cancer | |
| MA45146A (fr) | Dérivés de pyrazolopyridine pour le traitement du cancer | |
| EP3431105A4 (fr) | Composition médicinale pour le traitement du cancer | |
| MA47501A (fr) | Dérivé de di-nucléotides cycliques pour le traitement du cancer | |
| EP3634417A4 (fr) | Dérivés quinazoline-pyrazole pour le traitement de troubles liés au cancer | |
| MA50409A (fr) | Polythérapies pour le traitement du cancer | |
| MA48637A (fr) | Polythérapies pour le traitement du cancer | |
| EP3432927A4 (fr) | Inhibiteurs trispécifiques pour le traitement du cancer | |
| EP3436002A4 (fr) | Combinaisons pharmaceutiques pour le traitement du cancer | |
| MA47719A (fr) | Esketamine pour le traitement de la dépression | |
| EP3452060A4 (fr) | Polythérapie pour le traitement du cancer | |
| EP3494142A4 (fr) | Anticorps anti-siglec-7 pour le traitement du cancer | |
| MA41449A (fr) | Polythérapies pour le traitement de cancers | |
| EP3400010A4 (fr) | Combinaisons anti-her2 pour le traitement des tumeurs | |
| EP3630196A4 (fr) | Polythérapies pour le traitement de cancers | |
| EP3389645A4 (fr) | Combinaisons pour le traitement du cancer | |
| MA43000A (fr) | Polythérapie pour le traitement de tumeurs malignes | |
| EP3359255A4 (fr) | Polythérapies pour le traitement du cancer | |
| EP3474854A4 (fr) | Associations médicamenteuses pour le traitement du cancer | |
| EP3490561A4 (fr) | Combinaisons pour le traitement du cancer | |
| EP3454896A4 (fr) | Dérivés hétérocycliques pour le traitement de rsv | |
| EP3541417A4 (fr) | Immunothérapies d'association pour le traitement du cancer | |
| EP3383407A4 (fr) | Conjugués de cytarabine pour le traitement du cancer | |
| EP3947460A4 (fr) | Agents multispécifiques pour le traitement du cancer |