MA49652A - Régions de liaison à un antigène dirigées contre les domaines de la fibronectine de type iii et leurs procédés d'utilisation - Google Patents

Régions de liaison à un antigène dirigées contre les domaines de la fibronectine de type iii et leurs procédés d'utilisation

Info

Publication number
MA49652A
MA49652A MA049652A MA49652A MA49652A MA 49652 A MA49652 A MA 49652A MA 049652 A MA049652 A MA 049652A MA 49652 A MA49652 A MA 49652A MA 49652 A MA49652 A MA 49652A
Authority
MA
Morocco
Prior art keywords
antigen
fields
methods
type iii
binding regions
Prior art date
Application number
MA049652A
Other languages
English (en)
Inventor
Chichi Huang
John Lee
Jill Mooney
Michael Naso
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA49652A publication Critical patent/MA49652A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA049652A 2017-07-17 2018-07-17 Régions de liaison à un antigène dirigées contre les domaines de la fibronectine de type iii et leurs procédés d'utilisation MA49652A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762533341P 2017-07-17 2017-07-17
US201862625576P 2018-02-02 2018-02-02

Publications (1)

Publication Number Publication Date
MA49652A true MA49652A (fr) 2020-05-27

Family

ID=65000212

Family Applications (1)

Application Number Title Priority Date Filing Date
MA049652A MA49652A (fr) 2017-07-17 2018-07-17 Régions de liaison à un antigène dirigées contre les domaines de la fibronectine de type iii et leurs procédés d'utilisation

Country Status (11)

Country Link
US (2) US11161897B2 (fr)
EP (1) EP3655026A4 (fr)
JP (1) JP7280238B2 (fr)
KR (1) KR102869563B1 (fr)
CN (1) CN111093696B (fr)
AU (2) AU2018304173A1 (fr)
CA (1) CA3070100A1 (fr)
IL (1) IL271982B2 (fr)
MA (1) MA49652A (fr)
MX (1) MX2020000595A (fr)
WO (1) WO2019018402A2 (fr)

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* Cited by examiner, † Cited by third party
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JOP20220018A1 (ar) * 2019-07-26 2023-01-30 Janssen Biotech Inc مستقبل المستضدات الخيمري لـ hK2 المضاد (CAR)
US11628222B2 (en) * 2019-10-14 2023-04-18 Aro Biotherapeutics Company CD71 binding fibronectin type III domains
US20220380447A1 (en) * 2019-11-01 2022-12-01 The Trustees Of The University Of Pennsylvania Fibronectin targeting chimeric antigen receptors (cars)
CN115884778A (zh) * 2020-05-05 2023-03-31 Aro生物疗法公司 与前列腺特异性膜抗原结合的纤连蛋白iii型结构域和包含该结构域的细胞

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Also Published As

Publication number Publication date
CN111093696A (zh) 2020-05-01
IL271982A (en) 2020-02-27
JP7280238B2 (ja) 2023-05-23
WO2019018402A3 (fr) 2019-02-28
KR102869563B1 (ko) 2025-10-10
US12269870B2 (en) 2025-04-08
CN111093696B (zh) 2023-10-27
US20220127343A1 (en) 2022-04-28
WO2019018402A2 (fr) 2019-01-24
JP2020530766A (ja) 2020-10-29
EP3655026A2 (fr) 2020-05-27
US11161897B2 (en) 2021-11-02
IL271982B2 (en) 2025-02-01
AU2025204213A1 (en) 2025-06-26
AU2018304173A1 (en) 2020-01-30
IL271982B1 (en) 2024-10-01
MX2020000595A (es) 2020-09-10
EP3655026A4 (fr) 2021-07-28
CA3070100A1 (fr) 2019-01-24
KR20200028447A (ko) 2020-03-16
US20190016789A1 (en) 2019-01-17

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