MA45603A - Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble - Google Patents

Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Info

Publication number
MA45603A
MA45603A MA045603A MA45603A MA45603A MA 45603 A MA45603 A MA 45603A MA 045603 A MA045603 A MA 045603A MA 45603 A MA45603 A MA 45603A MA 45603 A MA45603 A MA 45603A
Authority
MA
Morocco
Prior art keywords
guanylate cyclase
new processes
soluble guanylate
preparing soluble
cyclase stimulators
Prior art date
Application number
MA045603A
Other languages
English (en)
French (fr)
Inventor
Vishnu Vardhan Reddy Karnati
Robert C Livingston
Song Xue
Original Assignee
Ironwood Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironwood Pharmaceuticals Inc filed Critical Ironwood Pharmaceuticals Inc
Publication of MA45603A publication Critical patent/MA45603A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
MA045603A 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble MA45603A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662359453P 2016-07-07 2016-07-07

Publications (1)

Publication Number Publication Date
MA45603A true MA45603A (fr) 2019-05-15

Family

ID=59416789

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045603A MA45603A (fr) 2016-07-07 2017-07-06 Nouveaux procédés de préparation de stimulateurs de la guanylate cyclase soluble

Country Status (16)

Country Link
US (3) US11319308B2 (cg-RX-API-DMAC7.html)
EP (2) EP3481818B1 (cg-RX-API-DMAC7.html)
JP (1) JP7112384B2 (cg-RX-API-DMAC7.html)
KR (1) KR102487872B1 (cg-RX-API-DMAC7.html)
CN (1) CN109563077A (cg-RX-API-DMAC7.html)
AU (1) AU2017291827B2 (cg-RX-API-DMAC7.html)
BR (1) BR112019000291A2 (cg-RX-API-DMAC7.html)
CA (1) CA3029375A1 (cg-RX-API-DMAC7.html)
CL (2) CL2019000016A1 (cg-RX-API-DMAC7.html)
EA (1) EA201990237A1 (cg-RX-API-DMAC7.html)
ES (1) ES2963563T3 (cg-RX-API-DMAC7.html)
IL (1) IL263995B (cg-RX-API-DMAC7.html)
MA (1) MA45603A (cg-RX-API-DMAC7.html)
MX (2) MX389920B (cg-RX-API-DMAC7.html)
SG (1) SG11201900096QA (cg-RX-API-DMAC7.html)
WO (1) WO2018009597A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7112384B2 (ja) 2016-07-07 2022-08-03 サイクレリオン・セラピューティクス,インコーポレーテッド 可溶性グアニル酸シクラーゼ刺激剤の新規な調製方法
SG10202100168XA (en) * 2016-07-07 2021-02-25 Cyclerion Therapeutics Inc Novel processes for preparation of soluble guanylate cyclase stimulators
WO2019161534A1 (en) * 2018-02-22 2019-08-29 Ironwood Pharmaceuticals, Inc. Novel processes and intermediates for preparation of soluble guanylate cyclase stimulators
AU2019206560B2 (en) 2018-01-10 2023-08-24 Cyclerion Therapeutics, Inc. Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2800618C (en) 2010-05-26 2018-08-28 Sunovion Pharmaceuticals Inc. Heteroaryl compounds and methods of use thereof
DK2588465T3 (en) 2010-06-30 2017-05-01 Ironwood Pharmaceuticals Inc SGC stimulators
EP2797915B1 (en) * 2011-12-27 2016-07-13 Ironwood Pharmaceuticals, Inc. 2-benzyl-3-(oxazole/thiazole)-5-(pyrimidin-2-yl)-1(H)-pyrazole derivatives as stimulators of the soluble guanylate cyclase (sGC) for the treatment of e.g. hypertension or heart failure
US9487508B2 (en) * 2012-09-19 2016-11-08 Ironwood Pharmaceuticals, Inc. SGC stimulators
KR102362835B1 (ko) * 2013-03-15 2022-02-14 사이클리온 테라퓨틱스, 인크. sGC 자극인자
EA032028B1 (ru) * 2013-12-11 2019-03-29 Айронвуд Фармасьютикалз, Инк. СТИМУЛЯТОРЫ рГЦ
BR112017005248A2 (pt) * 2014-09-17 2017-12-12 Ironwood Pharmaceuticals Inc estimuladores de sgc
WO2016044445A2 (en) * 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
AU2015317823A1 (en) * 2014-09-17 2017-03-23 Ironwood Pharmaceuticals, Inc. sGC stimulators
WO2016044447A1 (en) 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Pyrazole derivatives as sgc stimulators
KR102841419B1 (ko) * 2015-11-30 2025-08-01 사이클리온 테라퓨틱스, 인크. sGC 자극제를 포함하는 고체 분산물
AU2017292818B2 (en) * 2016-07-07 2021-10-21 Cyclerion Therapeutics, Inc. Solid forms of an sGC stimulator
JP7112384B2 (ja) 2016-07-07 2022-08-03 サイクレリオン・セラピューティクス,インコーポレーテッド 可溶性グアニル酸シクラーゼ刺激剤の新規な調製方法
SG10202100168XA (en) * 2016-07-07 2021-02-25 Cyclerion Therapeutics Inc Novel processes for preparation of soluble guanylate cyclase stimulators
EA202091502A1 (ru) * 2017-12-19 2020-11-12 Сайклерион Терапьютикс, Инк. СТИМУЛЯТОРЫ sGC
AU2019206560B2 (en) * 2018-01-10 2023-08-24 Cyclerion Therapeutics, Inc. Novel processes and intermediates for the preparation of soluble guanylate cyclase stimulators

Also Published As

Publication number Publication date
US20240059684A1 (en) 2024-02-22
EP4249488A3 (en) 2023-12-20
ES2963563T3 (es) 2024-03-27
CL2019000016A1 (es) 2019-05-03
AU2017291827A1 (en) 2019-02-07
SG11201900096QA (en) 2019-02-27
MX389920B (es) 2025-03-20
WO2018009597A1 (en) 2018-01-11
JP7112384B2 (ja) 2022-08-03
NZ750123A (en) 2025-02-28
AU2017291827B2 (en) 2021-10-21
KR20190025986A (ko) 2019-03-12
CL2023000228A1 (es) 2023-09-29
US11319308B2 (en) 2022-05-03
EA201990237A1 (ru) 2019-08-30
US20210323951A1 (en) 2021-10-21
IL263995B (en) 2021-02-28
JP2019525913A (ja) 2019-09-12
EP3481818C0 (en) 2023-09-06
EP4249488A2 (en) 2023-09-27
US20220227748A1 (en) 2022-07-21
EP3481818B1 (en) 2023-09-06
CA3029375A1 (en) 2018-01-11
MX2019000105A (es) 2019-04-22
IL263995A (en) 2019-02-28
CN109563077A (zh) 2019-04-02
US11773089B2 (en) 2023-10-03
KR102487872B1 (ko) 2023-01-12
EP3481818A1 (en) 2019-05-15
MX2022001495A (es) 2022-03-11
BR112019000291A2 (pt) 2019-04-16

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