MA41790A - Dérivé de morphinane - Google Patents

Dérivé de morphinane

Info

Publication number
MA41790A
MA41790A MA041790A MA41790A MA41790A MA 41790 A MA41790 A MA 41790A MA 041790 A MA041790 A MA 041790A MA 41790 A MA41790 A MA 41790A MA 41790 A MA41790 A MA 41790A
Authority
MA
Morocco
Prior art keywords
morphinane derivative
morphinane
derivative
Prior art date
Application number
MA041790A
Other languages
English (en)
Other versions
MA41790B1 (fr
Inventor
Hideaki Fujii
Kohei Hayashida
Masaaki Hirose
Hiroshi Nagase
Eriko Nakata
Isao Ooi
Akiyoshi Saitoh
Original Assignee
Nippon Chemiphar Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56919074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA41790(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Chemiphar Co filed Critical Nippon Chemiphar Co
Publication of MA41790A publication Critical patent/MA41790A/fr
Publication of MA41790B1 publication Critical patent/MA41790B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MA41790A 2015-03-17 2016-03-17 Dérivé de morphinane MA41790B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015054079 2015-03-17
PCT/JP2016/058475 WO2016148232A1 (fr) 2015-03-17 2016-03-17 Dérivé de morphinane

Publications (2)

Publication Number Publication Date
MA41790A true MA41790A (fr) 2021-06-02
MA41790B1 MA41790B1 (fr) 2022-02-28

Family

ID=56919074

Family Applications (1)

Application Number Title Priority Date Filing Date
MA41790A MA41790B1 (fr) 2015-03-17 2016-03-17 Dérivé de morphinane

Country Status (24)

Country Link
US (4) US10442802B2 (fr)
EP (2) EP3974430A1 (fr)
JP (4) JP6692345B2 (fr)
KR (2) KR102551969B1 (fr)
CN (3) CN107614500B (fr)
AU (2) AU2016234222C1 (fr)
BR (1) BR112017019805B1 (fr)
CA (1) CA2979023C (fr)
CY (1) CY1124908T1 (fr)
DK (1) DK3272750T3 (fr)
ES (1) ES2904511T3 (fr)
HK (1) HK1249900A1 (fr)
HU (1) HUE057266T2 (fr)
IL (1) IL254473B (fr)
MA (1) MA41790B1 (fr)
MX (2) MX2021008741A (fr)
MY (1) MY197742A (fr)
PH (1) PH12017501655B1 (fr)
PL (1) PL3272750T3 (fr)
RU (1) RU2762567C2 (fr)
SG (2) SG11201707427TA (fr)
TW (2) TWI778933B (fr)
WO (1) WO2016148232A1 (fr)
ZA (1) ZA201706882B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210371422A1 (en) 2016-08-09 2021-12-02 Nippon Chemiphar Co., Ltd. Morphinan derivative
AU2017327304B9 (en) * 2016-09-16 2023-10-12 Nippon Chemiphar Co., Ltd. Use of morphinan derivative for therapeutic treatment of opioid δ receptor agonist-related disease
JP7283711B2 (ja) * 2016-10-03 2023-05-30 学校法人星薬科大学 モルヒナン誘導体を含む医薬組成物及びその鎮痛剤への使用
AU2020318159A1 (en) 2019-07-19 2022-02-10 Nippon Chemiphar Co., Ltd. Method for producing morphinan derivative
CN114127069A (zh) 2019-07-19 2022-03-01 日本化学药品株式会社 苯酚衍生物的制造方法
EP4206203A1 (fr) 2020-08-28 2023-07-05 Nippon Chemiphar Co., Ltd. Procédé de préparation d'un dérivé de morphinane à chaîne principale formée d'éther diarylique utilisant un nouveau catalyseur au cuivre

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005231995A (ja) 1999-12-22 2005-09-02 Meiji Seika Kaisha Ltd オピオイドδ受容体アゴニスト/アンタゴニストとして有用なスピロ化合物
DE10161963A1 (de) 2001-12-17 2003-07-03 Johannes Schuetz 6-Aminomorphinanderivate, Herstellungsverfahren dafür und deren Verwendung
AR044010A1 (es) 2003-04-11 2005-08-24 Janssen Pharmaceutica Nv Uso de derivados de 4-fenil-4- [1h-imidazol-2-il]- piperidina sustituidos como agonistas delta opioideos no peptidos selectivos, con actividad antidepresiva y ansiolitica
US20110053969A1 (en) 2005-04-04 2011-03-03 Astrazeneca Ab Novel diazasipiroakanes and their use for treatment of ccr8 mediated diseases
WO2008001859A1 (fr) 2006-06-30 2008-01-03 School Juridical Person Kitasato Gakuen AGONISTE DES RÉCEPTEURS δ DES OPIOÏDES
US20110130406A1 (en) 2007-09-06 2011-06-02 Array Biopharma Inc. Pyrazolo-pyridines as tyrosine kinase inhibitors
RU2543484C2 (ru) 2009-10-30 2015-03-10 Янссен Фармацевтика Нв Пиразины для использования в качестве модуляторов дельта-опиоидных рецепторов
WO2011090935A1 (fr) 2010-01-19 2011-07-28 Merck Sharp & Dohme Corp. Composés pyrazolo[1,5-a]pyrimidines en tant qu'inhibiteurs de mtor
WO2012088494A1 (fr) 2010-12-23 2012-06-28 Pheonix Pharmalabs, Inc. Nouveaux morphinanes utiles en tant qu'analgésiques
JP2014073964A (ja) 2011-01-28 2014-04-24 Kitasato Institute モルヒナン誘導体
US8952030B2 (en) * 2011-09-09 2015-02-10 The Kitasato Institute Morphinan derivative
WO2014021273A1 (fr) * 2012-07-30 2014-02-06 学校法人北里研究所 Dérivés morphinane
JP6163210B2 (ja) 2012-12-14 2017-07-12 パーデュー、ファーマ、リミテッド、パートナーシップ 窒素含有モルフィナン誘導体およびその使用
JP6173431B2 (ja) * 2013-03-08 2017-08-02 学校法人北里研究所 モルヒナン誘導体
AU2017327304B9 (en) 2016-09-16 2023-10-12 Nippon Chemiphar Co., Ltd. Use of morphinan derivative for therapeutic treatment of opioid δ receptor agonist-related disease

Also Published As

Publication number Publication date
KR20180002616A (ko) 2018-01-08
ZA201706882B (en) 2022-02-23
EP3974430A1 (fr) 2022-03-30
EP3272750A1 (fr) 2018-01-24
CA2979023C (fr) 2023-09-26
CN113292559B (zh) 2024-04-02
US10442802B2 (en) 2019-10-15
US20200079775A1 (en) 2020-03-12
JP7375076B2 (ja) 2023-11-07
ES2904511T3 (es) 2022-04-05
JPWO2016148232A1 (ja) 2018-03-08
CN107614500B (zh) 2021-06-15
CN113292558A (zh) 2021-08-24
JP2022081656A (ja) 2022-05-31
AU2020270503B9 (en) 2023-10-12
MX2017011824A (es) 2018-04-20
TWI778933B (zh) 2022-09-21
AU2020270503A1 (en) 2020-12-17
EP3272750B1 (fr) 2021-11-03
HK1249900A1 (zh) 2018-11-16
US20230159530A1 (en) 2023-05-25
TWI775723B (zh) 2022-09-01
AU2020270503B2 (en) 2023-02-02
AU2020270503C9 (en) 2024-02-29
MY197742A (en) 2023-07-12
PH12017501655A1 (en) 2018-03-12
KR102551969B1 (ko) 2023-07-05
WO2016148232A1 (fr) 2016-09-22
IL254473A0 (en) 2017-11-30
SG11201707427TA (en) 2017-10-30
KR20230104767A (ko) 2023-07-10
AU2020270503C1 (en) 2023-08-10
EP3272750A4 (fr) 2018-08-08
US11643411B2 (en) 2023-05-09
SG10201907667RA (en) 2019-09-27
US20180057493A1 (en) 2018-03-01
CA2979023A1 (fr) 2016-09-22
AU2016234222A1 (en) 2017-10-26
PL3272750T3 (pl) 2022-03-07
CY1124908T1 (el) 2023-01-05
TW201638089A (zh) 2016-11-01
AU2016234222B2 (en) 2020-08-27
HUE057266T2 (hu) 2022-05-28
JP2024010098A (ja) 2024-01-23
CN107614500A (zh) 2018-01-19
CN113292559A (zh) 2021-08-24
MX2021008741A (es) 2022-11-01
MA41790B1 (fr) 2022-02-28
PH12017501655B1 (en) 2018-03-12
JP2020117533A (ja) 2020-08-06
AU2016234222C1 (en) 2021-02-11
US20210040094A1 (en) 2021-02-11
JP6692345B2 (ja) 2020-05-13
IL254473B (en) 2022-05-01
BR112017019805B1 (pt) 2023-01-31
RU2762567C2 (ru) 2021-12-21
RU2017134286A3 (fr) 2019-04-19
DK3272750T3 (en) 2022-01-03
BR112017019805A2 (pt) 2018-05-29
RU2017134286A (ru) 2019-04-05
US10995092B2 (en) 2021-05-04
TW202244044A (zh) 2022-11-16

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