MA38096B1 - Solutions mydriatiques et anti-inflammatoires stables sans agents de conservation destinees a etre injectees - Google Patents
Solutions mydriatiques et anti-inflammatoires stables sans agents de conservation destinees a etre injecteesInfo
- Publication number
- MA38096B1 MA38096B1 MA38096A MA38096A MA38096B1 MA 38096 B1 MA38096 B1 MA 38096B1 MA 38096 A MA38096 A MA 38096A MA 38096 A MA38096 A MA 38096A MA 38096 B1 MA38096 B1 MA 38096B1
- Authority
- MA
- Morocco
- Prior art keywords
- preservatives
- injection
- mydriatic
- stable
- inflammatory
- Prior art date
Links
- 238000002347 injection Methods 0.000 title abstract 2
- 239000007924 injection Substances 0.000 title abstract 2
- 239000003755 preservative agent Substances 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 230000002911 mydriatic effect Effects 0.000 title 1
- 239000000243 solution Substances 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- OZWKMVRBQXNZKK-UHFFFAOYSA-N ketorolac Chemical compound OC(=O)C1CCN2C1=CC=C2C(=O)C1=CC=CC=C1 OZWKMVRBQXNZKK-UHFFFAOYSA-N 0.000 abstract 1
- 229960004752 ketorolac Drugs 0.000 abstract 1
- 239000012669 liquid formulation Substances 0.000 abstract 1
- SONNWYBIRXJNDC-VIFPVBQESA-N phenylephrine Chemical compound CNC[C@H](O)C1=CC=CC(O)=C1 SONNWYBIRXJNDC-VIFPVBQESA-N 0.000 abstract 1
- 229960001802 phenylephrine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/08—Mydriatics or cycloplegics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Environmental Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Surgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261718026P | 2012-10-24 | 2012-10-24 | |
| US201261736179P | 2012-12-12 | 2012-12-12 | |
| PCT/US2013/066349 WO2014066485A1 (en) | 2012-10-24 | 2013-10-23 | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA38096A1 MA38096A1 (fr) | 2016-10-31 |
| MA38096B1 true MA38096B1 (fr) | 2019-12-31 |
Family
ID=50545210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38096A MA38096B1 (fr) | 2012-10-24 | 2013-10-23 | Solutions mydriatiques et anti-inflammatoires stables sans agents de conservation destinees a etre injectees |
Country Status (39)
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1534313T1 (sl) | 2002-07-30 | 2013-03-29 | Omeros Corporation | Oftalmološke raztopine in postopek za izpiranje |
| AU2013201465B2 (en) * | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| MX2016004257A (es) | 2013-10-03 | 2016-08-17 | Imprimis Pharmaceuticals Inc | Composiciones oftalmicas basadas en epinefrina para la administracion intraocular y metodos para su frabricacion. |
| US20210346318A1 (en) * | 2013-10-03 | 2021-11-11 | Harrow Ip, Llc | Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof |
| TWI809304B (zh) * | 2014-12-01 | 2023-07-21 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
| CN104856990A (zh) * | 2015-05-07 | 2015-08-26 | 武汉武药科技有限公司 | 去氧肾上腺素酮咯酸溶液及制备方法 |
| US11213480B1 (en) | 2015-08-06 | 2022-01-04 | Hikma Pharmaceuticals International Limited | Phenylephrine hydrochloride ready-to-use solution |
| USD831868S1 (en) | 2015-09-17 | 2018-10-23 | Lume Cube, Inc. | Compact external light |
| US10704745B2 (en) | 2015-10-13 | 2020-07-07 | Lume Cube, Inc. | Mobile light source |
| JP2019524896A (ja) | 2016-08-25 | 2019-09-05 | ハーロウ・ヘルス・インコーポレイテッドＨａｒｒｏｗ Ｈｅａｌｔｈ， Ｉｎｃ． | 眼内投与のためのエピネフリンベースの眼科組成物及びその製造方法 |
| US20180318319A1 (en) * | 2017-05-04 | 2018-11-08 | Ocular Science, Inc. | Compositions and Methods for Treating Eyes and Methods of Preparation |
| JP7078843B2 (ja) * | 2018-03-26 | 2022-06-01 | サミー株式会社 | 遊技機 |
| JP7670945B2 (ja) * | 2018-10-26 | 2025-05-01 | オーパス・ジェネティクス・インコーポレイテッド | 老眼、散瞳、および他の眼障害の治療のための方法および組成物 |
| US11071724B2 (en) | 2019-05-17 | 2021-07-27 | Ocular Science, Inc. | Compositions and methods for treating presbyopia |
| DE102019125430B3 (de) * | 2019-09-20 | 2020-11-19 | Carl Zeiss Meditec Ag | Steuerungsvorrichtung für ein ophthalmochirurgisches System, ophthalmochirurgisches System sowie Computerprogrammprodukt |
| KR102749980B1 (ko) | 2020-01-02 | 2025-01-03 | 삼성전자주식회사 | 에어 스페이서를 가지는 반도체 소자 |
| WO2021150747A1 (en) * | 2020-01-22 | 2021-07-29 | Nevakar Inc. | Phenylephrine hydrochloride compositions and containers |
| EP4262809A4 (en) * | 2020-12-17 | 2024-10-23 | Harrow IP, LLC | MYDRIATIC COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF |
| CN115368310B (zh) | 2021-05-18 | 2025-06-27 | 奥库菲尔医药公司 | 合成甲磺酸酚妥拉明的方法 |
| US20230039551A1 (en) | 2021-07-23 | 2023-02-09 | Somerset Therapeutics, Llc | Buffer- and chelator-free, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof |
| US12029729B2 (en) | 2021-07-23 | 2024-07-09 | Somerset Therapeutics, Llc | Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof |
| WO2024086268A1 (en) * | 2022-10-19 | 2024-04-25 | Fresenius Kabi Austria Gmbh | Phenylephrine liquid formulations |
| CN115950992B (zh) * | 2023-03-15 | 2023-06-09 | 苏州朗易生物医药研究有限公司 | 一种去氧肾上腺素酮咯酸溶液中有关物质的检测方法及其应用 |
| WO2025165753A1 (en) * | 2024-01-31 | 2025-08-07 | Hikma Pharmaceuticals Usa Inc. | Pharmaceutical formulations of phenylephrine and process of making the same |
Family Cites Families (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4402949A (en) | 1979-11-12 | 1983-09-06 | Sandoz Ltd. | Stable solutions of hydrogenated ergotalkaloids |
| US4550022A (en) | 1981-10-05 | 1985-10-29 | Alcon Laboratories, Inc. | Tissue irrigating solution |
| JPS58126810A (ja) | 1981-12-24 | 1983-07-28 | Kaken Pharmaceut Co Ltd | 抗炎症眼科用液剤およびその製法 |
| US4474751A (en) | 1983-05-16 | 1984-10-02 | Merck & Co., Inc. | Ophthalmic drug delivery system utilizing thermosetting gels |
| JPS6017053U (ja) | 1983-07-11 | 1985-02-05 | 住友電気工業株式会社 | 伝送エラ−検出器 |
| WO1987007141A1 (en) | 1986-05-23 | 1987-12-03 | New England Medical Center Hospitals, Inc. | Method for treating glaucoma |
| US5212196A (en) | 1986-10-21 | 1993-05-18 | Alcon Laboratories, Inc. | Control of post-surgical intraocular pressure using clonidine derivatives |
| US4938970A (en) | 1987-02-06 | 1990-07-03 | Hustead Robert E | Painless electrolyte solutions |
| US5110493A (en) | 1987-09-11 | 1992-05-05 | Syntex (U.S.A.) Inc. | Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant |
| US4876250A (en) | 1988-10-31 | 1989-10-24 | Alcon Laboratories, Inc. | Methods for controlling ocular hypertension with angiostatic steroids |
| DE3833893A1 (de) | 1988-10-05 | 1990-04-12 | Bayer Ag | Verwendung von basischen nitro-phenyl-dihydropyridin-amiden als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung ueber neue zwischenprodukte |
| US5036046A (en) | 1988-10-12 | 1991-07-30 | Eye Research Institute Of Retina Foundation, Inc. | Method for enhancing healing of corneal endothelial wounds |
| US5051443A (en) | 1988-10-12 | 1991-09-24 | Eye Research Institute Of Retina Foundation, Inc. | Method for enhancing healing of corneal endothelial wounds |
| US5371078A (en) | 1988-10-31 | 1994-12-06 | Alcon Laboratories, Inc. | Angiostatic steroids and methods and compositions for controlling ocular hypertension |
| US5116868A (en) | 1989-05-03 | 1992-05-26 | The Johns Hopkins University | Effective ophthalmic irrigation solution |
| CA2065375A1 (en) | 1989-08-21 | 1991-02-22 | Richard J. Sharpe | Method and composition for the treatment of cutaneous, ocular, and mucosal hypersensitivity, inflammation, and hyperproliferative conditions using topical preparations of serotonin antagonists |
| US5679650A (en) * | 1993-11-24 | 1997-10-21 | Fukunaga; Atsuo F. | Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine |
| CA2073003A1 (en) | 1990-09-07 | 1992-03-08 | Universidad De Alicante | Composition for treating ocular pain |
| US5318780A (en) | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| IT1252692B (it) | 1991-11-27 | 1995-06-23 | Zambon Spa | Composizione farmaceutica per uso oftalmico contenente un antiinfiammatorio non steroideo ed un decongestionante come principi attivi |
| JPH07502544A (ja) | 1992-10-21 | 1995-03-16 | アルコン ラボラトリーズ，インコーポレイテッド | 眼内組織潅注用および眼内外科処置中の瞳孔散大維持用組成物 |
| US6117907A (en) | 1993-04-14 | 2000-09-12 | Sher; Neal A. | Topical treatment of ocular pain after corneal surgery |
| WO1995009003A1 (en) | 1993-09-29 | 1995-04-06 | Alcon Laboratories, Inc. | Compositions containing growth factors and antimetabolites |
| EP0670733A1 (en) | 1993-09-29 | 1995-09-13 | Alcon Laboratories, Inc. | Compositions containing growth factors and antiplastic agents |
| US5624893A (en) | 1993-10-14 | 1997-04-29 | Alcon Laboratories, Inc. | Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation |
| JPH09506620A (ja) | 1993-12-17 | 1997-06-30 | アルコン・ラボラトリーズ，インコーポレイテッド | 非ステロイド抗炎症剤を含有する改良された眼内洗浄溶液 |
| US6350781B1 (en) | 1994-01-14 | 2002-02-26 | Lee Shahinia, Jr. | Method and analgesic preparations for sustained and extended corneal analgesia with subanesthetic concentrations of lidocaine |
| WO1995034298A1 (en) | 1994-06-10 | 1995-12-21 | Telor Ophthalmic Pharmaceuticals, Inc. | Inhibition of intraoperative miosis/production of mydriasis by local anesthetics |
| US5523316A (en) | 1994-06-23 | 1996-06-04 | Alcon Laboratories, Inc. | Intraocular irrigating solution containing agent for controlling IOP |
| US6492332B1 (en) | 1995-12-12 | 2002-12-10 | Omeros Corporation | Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation |
| WO2000023072A1 (en) | 1998-10-20 | 2000-04-27 | Omeros Medical Systems, Inc. | Irrigation solution containing mapk inhibitors and their use for treating pain and inflammation |
| WO2000023061A2 (en) | 1998-10-21 | 2000-04-27 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain and inflammation |
| MX9703988A (es) | 1994-12-12 | 1998-02-28 | Omeros Med Sys Inc | SOLUCIaN Y MÉTODO DE IRRIGACIaN PARA LA INHIBICIaN DEL DOLOR, LA INFLAMACIaN Y ES ESPASMO. |
| AU4467396A (en) | 1994-12-12 | 1996-07-10 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain, inflammation and spasm |
| US7091181B2 (en) | 1994-12-12 | 2006-08-15 | Omeros Corporation | Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors |
| KR100517210B1 (ko) | 1994-12-12 | 2006-06-07 | 오메로스 코포레이션 | 통증,염증및경련억제용관주용액 |
| US5972326A (en) | 1995-04-18 | 1999-10-26 | Galin; Miles A. | Controlled release of pharmaceuticals in the anterior chamber of the eye |
| US5612027A (en) | 1995-04-18 | 1997-03-18 | Galin; Miles A. | Controlled release of miotic and mydriatic drugs in the anterior chamber |
| US5767105A (en) | 1995-05-03 | 1998-06-16 | Peyman; Gholam A. | Ocular solution |
| US5798356A (en) | 1995-08-07 | 1998-08-25 | Alcon Laboratories, Inc. | Angiostatic compounds |
| US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| US6413961B1 (en) | 1995-12-12 | 2002-07-02 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain and inflammation |
| US6280745B1 (en) | 1997-12-23 | 2001-08-28 | Alliance Pharmaceutical Corp. | Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions |
| EP1039818A4 (en) | 1996-07-26 | 2001-11-07 | Schein Dental Equipment Co | ARMREST MECHANISM FOR DENTAL ARMCHAIRS |
| GB9704352D0 (en) | 1997-03-03 | 1997-04-23 | Chiroscience Ltd | Levobupivacaine and its use |
| WO1998043619A2 (en) | 1997-04-02 | 1998-10-08 | The Regents Of The University Of California | Method of local anesthesia |
| US5811446A (en) | 1997-04-18 | 1998-09-22 | Cytos Pharmaceuticals Llc | Prophylactic and therapeutic methods for ocular degenerative diseases and inflammations and histidine compositions therefor |
| US6034256A (en) | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
| US6495598B1 (en) | 1997-04-22 | 2002-12-17 | Ophtecs Corporation | Perfusate preparation for ophthalmic operation |
| EP0903151A1 (en) | 1997-09-22 | 1999-03-24 | ASTA Medica Aktiengesellschaft | Use of combinations comprising non-sedating antihistamines and alpha-adrenergic drugs for the topical treatment of rhinitis/conjunctivitis and cold, cold-like and/or flu symptoms |
| EP1091733B1 (en) | 1998-07-01 | 2005-12-07 | Warner-Lambert Company Llc | (-)-pseudoephedrine as a sympathomimetic drug |
| JP2002520355A (ja) | 1998-07-14 | 2002-07-09 | アルコン ラボラトリーズ， インコーポレイテッド | 非アレルギー性眼炎症障害を処置および眼新生血管形成を予防する医薬製造のための、１１−（３−ジメチルアミノプロピリデン）−６，１１−ジヒドロジベンズ［ｂ，ｅ］オキセピン−２−酢酸の使用 |
| US6262066B1 (en) | 1998-07-27 | 2001-07-17 | Schering Corporation | High affinity ligands for nociceptin receptor ORL-1 |
| FR2782721B1 (fr) | 1998-09-01 | 2000-11-03 | Inst Nat Sante Rech Med | Nouveaux composes phosphohalohydrines, procede de fabrication et applications |
| US6395746B1 (en) | 1998-09-30 | 2002-05-28 | Alcon Manufacturing, Ltd. | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation |
| US7973068B2 (en) | 1998-10-20 | 2011-07-05 | Omeros Corporation | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation |
| EP1227807B1 (en) | 1998-10-20 | 2005-03-30 | Omeros Corporation | Irrigation solution and method for inhibition of pain and inflammation |
| US20030087962A1 (en) | 1998-10-20 | 2003-05-08 | Omeros Corporation | Arthroscopic irrigation solution and method for peripheral vasoconstriction and inhibition of pain and inflammation |
| AU1214900A (en) | 1998-10-20 | 2000-05-08 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain and inflammation |
| AU1345000A (en) | 1998-11-05 | 2000-05-22 | Omeros Medical Systems, Inc. | Irrigation solution and method for inhibition of pain and inflammation |
| AU3119100A (en) | 1998-12-17 | 2000-07-03 | Alcon Laboratories, Inc. | Methods for the prevention and treatment of post-surgical complications |
| IL145226A0 (en) * | 1999-03-02 | 2002-06-30 | Vitreo Retinal Technologies In | Agents for intravitreal administration to treat or prevent disorders of the eye |
| CN1353573A (zh) | 1999-05-14 | 2002-06-12 | 加利福尼亚大学董事会 | 对炎症介导感染的抗炎症治疗 |
| AU5286901A (en) | 1999-10-22 | 2001-06-18 | Transdermatech, Inc. | Topical anesthetic formulation |
| KR20030060771A (ko) | 2000-04-28 | 2003-07-16 | 메모리얼 슬로안-케터링 캔서 센터 | 국소용 마취제/아편양약물 제제 및 이들의 용도 |
| US6218428B1 (en) | 2000-04-28 | 2001-04-17 | Emil Chynn | Ophthalmic composition |
| AU5754701A (en) | 2000-07-13 | 2002-01-30 | Pharmacia Corp | Method of using cox-2 inhibitors in the treatment and prevention of ocular cox-2mediated disorders |
| PE20020146A1 (es) | 2000-07-13 | 2002-03-31 | Upjohn Co | Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2) |
| PT2153819E (pt) | 2000-07-14 | 2012-11-14 | Allergan Inc | Utilização de um componente para aumento de solubilidade numa composição aquosa compreendendo tartarato de brimonidina |
| CN1450896A (zh) | 2000-07-28 | 2003-10-22 | 印斯拜尔药品股份有限公司 | 用吲哚衍生物降低眼内压的方法 |
| JP2002161032A (ja) | 2000-09-14 | 2002-06-04 | Taisho Pharmaceut Co Ltd | 粘膜適用組成物 |
| WO2002024191A1 (fr) | 2000-09-20 | 2002-03-28 | Yong Guang Pharmaceutical Co., Ltd. | Medicament permettant de traiter et de prevenir la myopie |
| US20020183279A1 (en) | 2001-04-18 | 2002-12-05 | Koichiro Tanaka | Pharmaceutical composition containing viscoelastic substance and medication |
| US20020198209A1 (en) | 2001-05-03 | 2002-12-26 | Allergan Sales Inc. | Compositions having enhanced pharmacokinetic characteristics |
| US20030191187A1 (en) * | 2002-04-01 | 2003-10-09 | Lee Fang Yu | Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same |
| SI1534313T1 (sl) * | 2002-07-30 | 2013-03-29 | Omeros Corporation | Oftalmološke raztopine in postopek za izpiranje |
| US7439241B2 (en) | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
| EP1833461A1 (en) * | 2004-12-22 | 2007-09-19 | Schering Corporation | Pharmaceutical formulations |
| EP1835911B1 (en) | 2004-12-23 | 2012-08-29 | ROXRO Pharma, Inc. | Therapeutic compositions for intranasal administration of ketorolac |
| FR2882930B1 (fr) | 2005-03-09 | 2009-03-27 | Walid Katib | Nouvelles compositions ophtalmologiques et leur mode d'utilisation |
| DOP2007000055A (es) * | 2006-04-10 | 2007-10-31 | Senosiain S A De C V Lab | Composición farmaceutica que comprende un analgésico y vitaminas |
| EP2185112A4 (en) | 2007-08-21 | 2012-01-18 | Harbor Biosciences Inc | Stabilized therapeutic compositions and formulations |
| BRPI0819105A2 (pt) | 2007-11-08 | 2019-09-24 | Aciex Therapeutics Inc | composição para o tratamento e prevenção de edema de pálpebra |
| WO2009074853A2 (en) | 2007-12-10 | 2009-06-18 | Promed Research Centre | Ophthalmic composition comprising phenylephrine |
| US7842714B2 (en) | 2008-03-03 | 2010-11-30 | Allergan, Inc. | Ketorolac tromethamine compositions for treating ocular pain |
| US9192571B2 (en) | 2008-03-03 | 2015-11-24 | Allergan, Inc. | Ketorolac tromethamine compositions for treating or preventing ocular pain |
| CN102413839A (zh) * | 2009-03-06 | 2012-04-11 | 医学免疫有限责任公司 | 人源化抗cd19抗体制剂 |
| US8277781B2 (en) | 2009-03-13 | 2012-10-02 | Luitpold Pharmaceuticals, Inc. | Device for intranasal administration |
| JP2012528889A (ja) | 2009-06-05 | 2012-11-15 | アーシエックス セラピューティックス， インコーポレイテッド | フルチカゾンの眼科処方物および使用方法 |
| JP2012528888A (ja) * | 2009-06-05 | 2012-11-15 | アーシエックス セラピューティックス， インコーポレイテッド | 眼科用配合剤、その製造方法およびその使用方法 |
| US8680510B2 (en) | 2010-06-28 | 2014-03-25 | International Business Machines Corporation | Method of forming compound semiconductor |
| PL2598119T3 (pl) | 2010-07-29 | 2019-03-29 | Allergan, Inc. | Niezawierające konserwantów roztwory brymonidyny i timololu |
| AU2013201465B2 (en) | 2012-10-24 | 2016-03-03 | Rayner Intraocular Lenses Limited | Stable preservative-free mydriatic and anti-inflammatory solutions for injection |
| TWI809304B (zh) | 2014-12-01 | 2023-07-21 | 奥默羅斯公司 | 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液 |
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