MA37880B1 - Formulation transdermique contenant des inhibiteurs de cox - Google Patents
Formulation transdermique contenant des inhibiteurs de coxInfo
- Publication number
- MA37880B1 MA37880B1 MA37880A MA37880A MA37880B1 MA 37880 B1 MA37880 B1 MA 37880B1 MA 37880 A MA37880 A MA 37880A MA 37880 A MA37880 A MA 37880A MA 37880 B1 MA37880 B1 MA 37880B1
- Authority
- MA
- Morocco
- Prior art keywords
- formulation containing
- transdermal formulation
- cox inhibitors
- containing cox
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La présente invention concerne des compositions de gel appropriées pour l'administration topique d'un composé actif présentant une faible solubilité et une propriété de pénétration cutanée, par exemple, de composés inhibiteurs de cox-2, leurs procédés de préparation et leurs méthodes d'utilisation pour le traitement d'indications pouvant être traitées au moyen du composé actif.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13/562,686 US10045935B2 (en) | 2012-07-31 | 2012-07-31 | Transdermal formulation containing COX inhibitors |
PCT/HU2013/000080 WO2014020366A1 (fr) | 2012-07-31 | 2013-07-31 | Formulation transdermique contenant des inhibiteurs de cox |
Publications (2)
Publication Number | Publication Date |
---|---|
MA37880A1 MA37880A1 (fr) | 2016-02-29 |
MA37880B1 true MA37880B1 (fr) | 2016-09-30 |
Family
ID=49231593
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA37880A MA37880B1 (fr) | 2012-07-31 | 2013-07-31 | Formulation transdermique contenant des inhibiteurs de cox |
Country Status (40)
Country | Link |
---|---|
US (2) | US10045935B2 (fr) |
EP (1) | EP2879664B1 (fr) |
JP (3) | JP6374383B2 (fr) |
KR (1) | KR20150032892A (fr) |
CN (1) | CN104768530B (fr) |
AU (2) | AU2013298294A1 (fr) |
BR (1) | BR112015002041B1 (fr) |
CA (1) | CA2880442C (fr) |
CL (1) | CL2015000240A1 (fr) |
CO (1) | CO7240432A2 (fr) |
CR (1) | CR20150044A (fr) |
CU (1) | CU24246B1 (fr) |
CY (1) | CY1123805T1 (fr) |
DK (1) | DK2879664T3 (fr) |
EA (1) | EA033950B1 (fr) |
EC (1) | ECSP15003613A (fr) |
ES (1) | ES2841992T3 (fr) |
GE (1) | GEP20176630B (fr) |
HK (1) | HK1211490A1 (fr) |
HR (1) | HRP20210008T1 (fr) |
HU (1) | HUE053418T2 (fr) |
IL (1) | IL236988B (fr) |
IN (1) | IN2015DN01329A (fr) |
LT (1) | LT2879664T (fr) |
MA (1) | MA37880B1 (fr) |
MD (1) | MD20150018A2 (fr) |
MX (1) | MX361697B (fr) |
NI (1) | NI201500007A (fr) |
NZ (1) | NZ704567A (fr) |
PE (1) | PE20150755A1 (fr) |
PH (1) | PH12015500200A1 (fr) |
PL (1) | PL2879664T3 (fr) |
PT (1) | PT2879664T (fr) |
RS (1) | RS61326B1 (fr) |
SG (1) | SG11201500734SA (fr) |
SI (1) | SI2879664T1 (fr) |
TN (1) | TN2015000037A1 (fr) |
UA (1) | UA116636C2 (fr) |
WO (1) | WO2014020366A1 (fr) |
ZA (1) | ZA201500744B (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10045965B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
US11154535B2 (en) | 2012-07-31 | 2021-10-26 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
US10045935B2 (en) * | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
CN108904812A (zh) * | 2018-08-27 | 2018-11-30 | 邛崃市医疗中心医院 | 以卡波姆协同透皮剂的高透皮性防治肩周炎的外用药物 |
CN114601789B (zh) * | 2022-03-29 | 2024-03-26 | 辽宁方诺生物科技有限公司 | 一种塞来昔布凝胶剂及其制备方法和应用 |
Family Cites Families (124)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3998973A (en) | 1975-04-07 | 1976-12-21 | R. T. Vanderbilt Company, Inc. | Thickening composition |
FR2339392A1 (fr) | 1976-02-02 | 1977-08-26 | Oreal | Compositions contenant des derives du silicium |
GB2050160A (en) | 1979-04-10 | 1981-01-07 | Nottage H C | Cosmetic protective cream |
FR2471778A1 (fr) | 1979-12-21 | 1981-06-26 | Oreal | Procede de traitement des cheveux en vue d'ameliorer leur aspect a l'aide d'une composition contenant un hydrolysat de lactalbumine |
EP0126138A1 (fr) | 1982-11-04 | 1984-11-28 | Redken Laboratories Inc. | Preparation cosmetique |
GB8320366D0 (en) | 1983-07-28 | 1983-09-01 | Gillette Co | Hair relaxing compositions |
GB8421112D0 (en) | 1984-08-20 | 1984-09-26 | Unilever Plc | Pyroglutamic acid esters |
GB8600568D0 (en) | 1986-01-10 | 1986-02-19 | Gillette Co | Hair relaxing compositions |
US4831023A (en) | 1986-06-27 | 1989-05-16 | Thames Pharmacal Co., Inc. | Water washable vehicles for topical use |
US4837019A (en) | 1986-08-11 | 1989-06-06 | Charles Of The Ritz Group Ltd. | Skin treatment composition and method for treating burned skin |
DE3805744C2 (de) | 1987-03-04 | 1999-09-23 | Novartis Ag | Phenylcarbamate zur Hemmung der Acetylcholinesterase |
US4720353A (en) | 1987-04-14 | 1988-01-19 | Richardson-Vicks Inc. | Stable pharmaceutical w/o emulsion composition |
DE3714140A1 (de) | 1987-04-28 | 1988-11-10 | Lohmann Therapie Syst Lts | Wirkstoffhaltiges pflaster zur kontrollierten verabreichung von wirkstoffen an die haut, seine verwendung sowie verfahren zur gesteuerten verabreichung von wirkstoffen an die haut |
US4906475A (en) | 1988-02-16 | 1990-03-06 | Paco Pharmaceutical Services | Estradiol transdermal delivery system |
JPH02145512A (ja) | 1988-11-26 | 1990-06-05 | Shin Etsu Chem Co Ltd | 被膜形成型外用剤 |
US5122519A (en) | 1989-06-27 | 1992-06-16 | American Cyanamid Company | Stable, cosmetically acceptable topical gel formulation and method of treatment for acne |
DE4131678A1 (de) | 1991-04-13 | 1992-10-15 | Beiersdorf Ag | Stabile multiple emulsionen |
AU2259692A (en) | 1991-07-03 | 1993-02-11 | Sano Corporation | Composition and method for transdermal delivery of diclofenac |
US5300286A (en) | 1992-07-14 | 1994-04-05 | Dow Corning Corporation | Silicone emulsion for personal care application |
US5210103A (en) | 1992-09-02 | 1993-05-11 | Basf Corporation | Volatile silicone oil-blown integral skin foam |
US5698589A (en) | 1993-06-01 | 1997-12-16 | International Medical Innovations, Inc. | Water-based topical cream containing nitroglycerin and method of preparation and use thereof |
GB9315755D0 (en) | 1993-07-30 | 1993-09-15 | Wellcome Found | Stabilized formulation |
FR2709131B1 (fr) | 1993-08-18 | 1995-11-10 | Cilag Laboratoire | Dispositif de distribution d'une substance thérapeutique ou cosmétique dont le véhicule inerte est un polydiorganosiloxane volatil, et composition destinée à être utilisée dans le dispositif. |
US5466823A (en) | 1993-11-30 | 1995-11-14 | G.D. Searle & Co. | Substituted pyrazolyl benzenesulfonamides |
US5620692A (en) | 1993-12-23 | 1997-04-15 | Nurture, Inc. | Oat oil compositions with useful cosmetic and dermatological properties |
GB9404248D0 (en) | 1994-03-05 | 1994-04-20 | Boots Co Plc | Pharmaceutical formulations |
US5451405A (en) | 1994-04-25 | 1995-09-19 | Chesebrough-Pond's Usa Co. | Skin treatment composition |
IL116539A (en) | 1995-01-06 | 2002-02-10 | Noven Pharma | Preparations given through the skin of unstable anti-acid drugs |
FR2738565B1 (fr) | 1995-09-13 | 1997-11-28 | Dior Christian Parfums | Produits extraits d'une plante du genre commiphora, en particulier de la plante commiphora mukul, et extraits en contenant et leurs applications notamment en cosmetique |
AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
AU2456097A (en) | 1996-05-21 | 1997-12-09 | Dermasciences, Inc. | Topical barrier composition containing silicone and bentonite |
GB9611167D0 (en) | 1996-05-29 | 1996-07-31 | Glaxo Group Ltd | Medicaments |
RU2185144C2 (ru) | 1996-06-28 | 2002-07-20 | Унилевер Н.В. | Жидкая композиция антиперспиранта/дезодоранта |
FR2751874B1 (fr) | 1996-08-02 | 1998-08-28 | Sederma Sa | Nouvelles compositions cosmetiques pour embellir et eclaircir la peau |
GB9618974D0 (en) | 1996-09-11 | 1996-10-23 | Glaxo Group Ltd | Medicaments |
US5756109A (en) | 1996-09-27 | 1998-05-26 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Skin care compositions containing geranyl geraniol and retinol or retinyl esters |
US5747051A (en) | 1996-09-27 | 1998-05-05 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an amide of a hydroxy fatty acid and a retinoid |
US5955097A (en) | 1996-10-18 | 1999-09-21 | Virotex Corporation | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
US6019997A (en) | 1997-01-09 | 2000-02-01 | Minnesota Mining And Manufacturing | Hydroalcoholic compositions for transdermal penetration of pharmaceutical agents |
DE19700913C2 (de) | 1997-01-14 | 2001-01-04 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Abgabe von Hormonen |
FR2763842B1 (fr) | 1997-05-27 | 2000-09-15 | Sederma Sa | Compositions cosmetiques ou dermopharmaceutiques contenant des derives de threonine ou de serine |
FR2768335B1 (fr) | 1997-09-12 | 2000-03-03 | Sederma Sa | Compositions a usage cosmetique ou dermopharmaceutique contenant une association d'extrait d'algue et d'exopolysaccharide |
IL122084A (en) | 1997-10-31 | 1999-09-22 | Lurident Ltd | Formulation for personal care with mucoadhesive properties |
DE19750029A1 (de) | 1997-11-12 | 1999-05-20 | Merck Patent Gmbh | Stabile kosmetische Formulierung enthaltend Butylmethoxydibenzoylmethan |
DE19750030A1 (de) | 1997-11-12 | 1999-05-20 | Merck Patent Gmbh | Lichtstabile kosmetische Formulierung enthaltend Butylmethoxydibenzoylmethan |
US6187300B1 (en) | 1997-12-17 | 2001-02-13 | The Procter & Gamble Company | Antiperspirant cream compositions having improved wash-off and antiperspirant efficacy |
US5851544A (en) | 1997-12-18 | 1998-12-22 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Cosmetic skin or hair care compositions containing fluorocarbons infused with carbon dioxide |
US20060015058A1 (en) | 1998-01-08 | 2006-01-19 | Kellogg Scott C | Agents and methods for enhancement of transdermal transport |
MXPA01000973A (es) | 1998-08-03 | 2002-06-04 | Epigenesis Pharmaceuticals Inc | Un nuevo agente analgesico antiinflamatorio y de cicatrizacion de heridas. |
US6284234B1 (en) | 1998-08-04 | 2001-09-04 | Johnson & Johnson Consumer Companies, Inc. | Topical delivery systems for active agents |
US6375986B1 (en) | 2000-09-21 | 2002-04-23 | Elan Pharma International Ltd. | Solid dose nanoparticulate compositions comprising a synergistic combination of a polymeric surface stabilizer and dioctyl sodium sulfosuccinate |
GB9828379D0 (en) | 1998-12-22 | 1999-02-17 | Unilever Plc | Skin care composition |
US6007829A (en) | 1998-12-17 | 1999-12-28 | Cheesebrough-Pond's Usa Co. | Cosmetic skin care compositions containing succinate compounds |
FR2791887B1 (fr) | 1999-04-06 | 2004-04-23 | Sederma Sa | Compositions cosmetiques ou dermopharmaceutiques renfermant des extraits vegetaux de pinus lambertania contre la secheresse cutanee de toute origine |
PT3146969T (pt) | 1999-04-23 | 2018-10-18 | Leo Pharma As | Composição farmacêutica para aplicação dérmica para uso no tratamento da psoríase compreendendo vitamina d e um corticosteroide |
KR100319473B1 (ko) | 1999-08-24 | 2002-01-05 | 김강권 | 실크아미노산 수용액을 주재로한 아이스크림류의 제조방법 |
US10179159B2 (en) | 1999-10-22 | 2019-01-15 | Scott Wepfer | Topical anesthetic formulation |
FR2802097B1 (fr) | 1999-12-14 | 2002-12-13 | Invest S Therapeutiques Essais | Composition sous forme de gel prevue pour recevoir un principe actif en solution ou en suspension, notamment pour application sur une muqueuse et procede de fabrication |
US20050074487A1 (en) | 1999-12-16 | 2005-04-07 | Tsung-Min Hsu | Transdermal and topical administration of drugs using basic permeation enhancers |
US6432415B1 (en) | 1999-12-17 | 2002-08-13 | Axrix Laboratories, Inc. | Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces |
DE10004790B4 (de) | 2000-02-01 | 2004-09-09 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Verabreichung von Zaleplon, Verfahren zu seiner Herstellung und seine Verwendung |
US6361806B1 (en) | 2000-02-23 | 2002-03-26 | Michael P. Allen | Composition for and method of topical administration to effect changes in subcutaneous adipose tissue |
CA2406024C (fr) | 2000-03-17 | 2012-05-22 | Avocet Polymer Technologies, Inc. | Procedes permettant d'ameliorer la taille et l'aspect d'une blessure |
US6800297B2 (en) | 2000-06-15 | 2004-10-05 | Acusphere, Inc. | Porous COX-2 inhibitor matrices and methods of manufacture thereof |
US6589557B2 (en) | 2000-06-15 | 2003-07-08 | Acusphere, Inc. | Porous celecoxib matrices and methods of manufacture thereof |
DE10032132A1 (de) | 2000-07-01 | 2002-01-17 | Lohmann Therapie Syst Lts | Dermales Therapeutisches System enthaltend nichtsteroidale Antiphlogistika mit selektiver COX-2-Hemmung |
IN191090B (fr) | 2000-08-29 | 2003-09-20 | Ranbanx Lab Ltd | |
DE10042411A1 (de) | 2000-08-30 | 2002-03-28 | Lohmann Therapie Syst Lts | Transdermales therapeutisches System zur Abgabe von Exemestan |
DE10042412B4 (de) | 2000-08-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System zur Abgabe von Venlafaxin, und seine Verwendung |
GB0027769D0 (en) | 2000-11-14 | 2000-12-27 | Unilever Plc | Cosmetic method of treating skin |
GB0028355D0 (en) | 2000-11-21 | 2001-01-03 | Unilever Plc | Cosmetic method of treating skin |
GB0028706D0 (en) | 2000-11-24 | 2001-01-10 | Unilever Plc | Cosmetic composition |
US8449908B2 (en) | 2000-12-22 | 2013-05-28 | Alltranz, Llc | Transdermal delivery of cannabidiol |
JP2004532871A (ja) | 2001-05-31 | 2004-10-28 | ファルマシア・コーポレーション | 皮膚浸透性シクロオキシゲナーゼ−2選択的阻害組成物 |
GB0119583D0 (en) | 2001-08-10 | 2001-10-03 | Unilever Plc | Cosmetic composition and method of treating skin |
CN1606445A (zh) * | 2001-10-23 | 2005-04-13 | 兰贝克塞实验室有限公司 | 用于局部传递环加氧酶-2酶抑制剂的药物组合物的制备方法 |
US20030104019A1 (en) | 2001-11-01 | 2003-06-05 | Mcculloch Laura | Composition for reducing enzymatic irritation to skin |
DE10164531A1 (de) | 2001-12-31 | 2003-07-17 | Pharmatech Gmbh | Zubereitung zur Oberflächenanästhesie der Haut |
US6838078B2 (en) | 2002-01-16 | 2005-01-04 | 3M Innovative Properties Company | Film-forming compositions and methods |
US20030180281A1 (en) | 2002-03-11 | 2003-09-25 | Bott Richard R. | Preparations for topical skin use and treatment |
EP1490030B2 (fr) | 2002-03-20 | 2010-07-14 | Elan Pharma International Limited | Compositions nanoparticulaires d'inhibiteurs d'angiogenese |
US20030199584A1 (en) | 2002-04-11 | 2003-10-23 | Ahluwalia Gurpreet S. | Reduction of hair growth |
US20030199537A1 (en) | 2002-04-18 | 2003-10-23 | Cannon John B. | Polymorph of a pharmaceutical |
JP2004075592A (ja) | 2002-08-14 | 2004-03-11 | Masahiko Abe | 非イオン性ベシクルおよびその利用 |
CH696420A5 (de) | 2002-09-13 | 2007-06-15 | Mepha Ag | Neue stabile Zubereitungen von Alkyl-, Phenyl-Pyridonen für topische Anwendung. |
US7138394B2 (en) | 2002-09-27 | 2006-11-21 | Alpharx Inc. | Vehicle for topical delivery of anti-inflammatory compounds |
US20060241175A1 (en) | 2002-09-27 | 2006-10-26 | Joseph Schwarz | Vehicle for topical delivery of anti-inflammatory compounds |
US20060159648A1 (en) | 2003-02-17 | 2006-07-20 | Davis Adrian F | Novel therapeutic method and compositions for topical administration |
EP1635771A2 (fr) | 2003-04-18 | 2006-03-22 | MERCK PATENT GmbH | Formulations cosmétiques comprenant des pigments antimicrobiens |
ITRM20030204A1 (it) | 2003-04-29 | 2004-10-30 | Provincia Italiana Della Congregazi One Dei Figli | Formulazione dermatologica. |
FR2854897B1 (fr) | 2003-05-12 | 2007-05-04 | Sederma Sa | Compositions cosmetiques ou dermopharmaceutiques pour reduire les signes du vieillissement cutane. |
EP1627644A4 (fr) | 2003-05-23 | 2012-01-18 | Hisamitsu Pharmaceutical Co | Preparation administree par voie percutanee externe et contenant une substance medicamenteuse anti-inflammatoire non steroidienne et un inhibiteur de production d'interleukine-1$g(a) |
WO2005000248A2 (fr) | 2003-06-25 | 2005-01-06 | Geron Corporation | Compositions et procedes de traitement de la peau |
ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
WO2005007129A2 (fr) | 2003-07-17 | 2005-01-27 | Angiotech International Ag | Formulations topiques a elements bioactifs |
JP2007508243A (ja) | 2003-08-04 | 2007-04-05 | フォーミックス エルティーディー. | 両親媒性コポリマーゲル化剤を含む泡坦体 |
EP1656097A1 (fr) | 2003-08-07 | 2006-05-17 | The Procter & Gamble Company | Emulsions eau dans l'huile |
WO2005044227A1 (fr) | 2003-11-05 | 2005-05-19 | Glenmark Pharmaceuticals Limited | Compositions pharmaceutiques topiques |
WO2005046600A2 (fr) | 2003-11-07 | 2005-05-26 | Nexmed Holdings, Inc. | Systeme d'application de tulobuterol transdermique, procede et composition correspondants |
FR2862871B1 (fr) | 2003-12-01 | 2008-05-30 | Camet Anne Dupouy | Composition cosmetique anti-pollution |
US20050255131A1 (en) | 2004-05-11 | 2005-11-17 | Mohan Vishnupad | Clindamycin compositions and delivery system therefor |
US7662855B2 (en) | 2004-05-11 | 2010-02-16 | Imaginative Research Associates, Inc. | Retinoid solutions and formulations made therefrom |
US20050255133A1 (en) | 2004-05-11 | 2005-11-17 | Alpharx Inc. | Topical composition for acne treatment |
US20070264319A1 (en) | 2004-09-01 | 2007-11-15 | Lebo David B | Transdermal Antiemesis Delivery System, Method and Composition Therefor |
US20070267035A1 (en) | 2004-09-07 | 2007-11-22 | Henkel Kommanditgesellschaft Auf Aktien | Composition and Method for the Smoothing of Fibres Containing Keratin |
CA2580659C (fr) | 2004-09-15 | 2013-02-26 | Ivx Animal Health, Inc. | Corticosteroide ayant une faible absorption systemique |
TW200616589A (en) | 2004-10-08 | 2006-06-01 | Noven Pharma | Transdermal delivery of drugs based on crystal size |
WO2006091297A2 (fr) | 2005-02-23 | 2006-08-31 | The Regents Of The University Of California | Molecules ameliorant l'administration percutanee et methodes de decouverte associees |
WO2006138035A1 (fr) | 2005-06-13 | 2006-12-28 | Dow Corning Corporation | Vehicule pour l'administration d'agents pharmaceutiques solubles lipidiques topiques |
CA2618993A1 (fr) | 2005-08-13 | 2007-02-22 | Collegium Pharmaceutical, Inc. | Administration topique a l'aide d'un fluide porteur |
WO2007051596A1 (fr) | 2005-11-03 | 2007-05-10 | Dsm Ip Assets B.V. | Nouveaux biotinates de rétinyle et applications |
KR100658436B1 (ko) | 2005-12-09 | 2006-12-27 | 한국화학연구원 | 아데노실코발라민 함유 피부질환 치료용 외용제 조성물 |
EP1978997A1 (fr) | 2005-12-22 | 2008-10-15 | Apollo Life Sciences Limited | Livraison transdermale d'agents pharmaceutiques |
US8974827B2 (en) | 2007-06-04 | 2015-03-10 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
HU227970B1 (en) * | 2007-07-10 | 2012-07-30 | Egis Gyogyszergyar Nyrt | Pharmaceutical compositions containing silicones of high volatility |
HUP0900072A2 (hu) | 2009-02-06 | 2010-09-28 | Egis Gyogyszergyar Nyilvanosan | Transzdermális gyógyszerkészítmények |
EP2178519B1 (fr) | 2007-07-13 | 2012-04-25 | Bend Research, Inc. | Nanoparticules comprenant un polymère non ionisable et un polymère cellulosique anionique |
WO2009031318A1 (fr) | 2007-09-05 | 2009-03-12 | Kowa Co., Ltd. | Préparation pour une application externe comprenant un agent analgésique/anti-inflammatoire |
WO2009063367A1 (fr) | 2007-11-15 | 2009-05-22 | Pfizer Products Inc. | Formes galéniques comprenant du célécoxib permettant un soulagement de la douleur à la fois rapide et prolongé |
WO2010047831A1 (fr) | 2008-10-23 | 2010-04-29 | Nycomed Us Inc. | Formulations de gel de métronidazole stables |
KR20110127687A (ko) | 2009-03-11 | 2011-11-25 | 코와 가부시키가이샤 | 진통·항염증제 함유 외용제 |
WO2010103845A1 (fr) * | 2009-03-11 | 2010-09-16 | 興和株式会社 | Préparation externe contenant un analgésique/anti-inflammatoire |
EP2575813A1 (fr) * | 2010-05-28 | 2013-04-10 | Nuvo Research Inc. | Formulation topique d'étoricoxib |
US10045935B2 (en) * | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
-
2012
- 2012-07-31 US US13/562,686 patent/US10045935B2/en active Active
-
2013
- 2013-07-31 HU HUE13766392A patent/HUE053418T2/hu unknown
- 2013-07-31 CN CN201380040919.7A patent/CN104768530B/zh active Active
- 2013-07-31 MX MX2015001387A patent/MX361697B/es active IP Right Grant
- 2013-07-31 AU AU2013298294A patent/AU2013298294A1/en not_active Abandoned
- 2013-07-31 BR BR112015002041-0A patent/BR112015002041B1/pt active IP Right Grant
- 2013-07-31 SG SG11201500734SA patent/SG11201500734SA/en unknown
- 2013-07-31 UA UAA201501715A patent/UA116636C2/uk unknown
- 2013-07-31 EP EP13766392.8A patent/EP2879664B1/fr active Active
- 2013-07-31 GE GEAP201313747A patent/GEP20176630B/en unknown
- 2013-07-31 MD MDA20150018A patent/MD20150018A2/ro not_active Application Discontinuation
- 2013-07-31 NZ NZ704567A patent/NZ704567A/en active IP Right Revival
- 2013-07-31 CA CA2880442A patent/CA2880442C/fr active Active
- 2013-07-31 PL PL13766392T patent/PL2879664T3/pl unknown
- 2013-07-31 ES ES13766392T patent/ES2841992T3/es active Active
- 2013-07-31 LT LTEP13766392.8T patent/LT2879664T/lt unknown
- 2013-07-31 PE PE2015000128A patent/PE20150755A1/es not_active Application Discontinuation
- 2013-07-31 SI SI201331835T patent/SI2879664T1/sl unknown
- 2013-07-31 EA EA201590269A patent/EA033950B1/ru unknown
- 2013-07-31 KR KR20157003458A patent/KR20150032892A/ko not_active Application Discontinuation
- 2013-07-31 JP JP2015524850A patent/JP6374383B2/ja active Active
- 2013-07-31 PT PT137663928T patent/PT2879664T/pt unknown
- 2013-07-31 DK DK13766392.8T patent/DK2879664T3/da active
- 2013-07-31 MA MA37880A patent/MA37880B1/fr unknown
- 2013-07-31 CU CUP2015000010A patent/CU24246B1/es unknown
- 2013-07-31 RS RS20210011A patent/RS61326B1/sr unknown
- 2013-07-31 WO PCT/HU2013/000080 patent/WO2014020366A1/fr active Application Filing
- 2013-07-31 IN IN1329DEN2015 patent/IN2015DN01329A/en unknown
-
2015
- 2015-01-29 CO CO15018217A patent/CO7240432A2/es unknown
- 2015-01-29 IL IL236988A patent/IL236988B/en active IP Right Grant
- 2015-01-29 PH PH12015500200A patent/PH12015500200A1/en unknown
- 2015-01-30 NI NI201500007A patent/NI201500007A/es unknown
- 2015-01-30 EC ECIEPI20153613A patent/ECSP15003613A/es unknown
- 2015-01-30 CR CR20150044A patent/CR20150044A/es unknown
- 2015-01-30 CL CL2015000240A patent/CL2015000240A1/es unknown
- 2015-01-30 TN TNP2015000037A patent/TN2015000037A1/fr unknown
- 2015-02-02 ZA ZA2015/00744A patent/ZA201500744B/en unknown
- 2015-04-09 US US14/682,973 patent/US20150231247A1/en not_active Abandoned
- 2015-12-17 HK HK15112445.9A patent/HK1211490A1/xx unknown
-
2018
- 2018-03-26 JP JP2018057364A patent/JP7210833B2/ja active Active
- 2018-04-26 AU AU2018202875A patent/AU2018202875B2/en active Active
-
2021
- 2021-01-05 HR HRP20210008TT patent/HRP20210008T1/hr unknown
- 2021-01-07 CY CY20211100005T patent/CY1123805T1/el unknown
- 2021-12-08 JP JP2021199410A patent/JP7384885B2/ja active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2022002465A (es) | Inhibidores de kras g12d. | |
MA35459B1 (fr) | Composés et compositions pouvant être utilisés en tant qu'inhibiteurs de la kinase c-kit | |
MA37880B1 (fr) | Formulation transdermique contenant des inhibiteurs de cox | |
MA40111B1 (fr) | Dérivés du tétrahydronaphtalène inhibant la protéine mcl-1 | |
MA39211B1 (fr) | Composés tricycliques comme agents anti-cancers | |
MA38483A1 (fr) | Inhibiteurs de l'ido | |
MA41251B1 (fr) | Dérivés de thiéno[2,3-c]pyrrol-4-one comme inhibiteurs erk | |
NZ706739A (en) | Substituted benzene compounds | |
EA201500394A1 (ru) | Ингибиторы деметилаз гистонов | |
TN2014000195A1 (fr) | 2-thiopyrimidinones | |
TR201908247T4 (tr) | Sodyum glikoz birlikte taşıyıcı 1 inhibitörleri. | |
MA35342B1 (fr) | Composés de-pipéridinyle utiles comme inhibiteurs de la tankyrase | |
TR201902125T4 (tr) | Si̇stemi̇k olarak etki̇ eden akti̇f ajanlari i̇çeren parazi̇ti̇si̇dal oral veteri̇nerli̇ğe ai̇t bi̇leşi̇mler, bunlarin yöntemleri̇ ve kullanimlari | |
MA47356B1 (fr) | Dérivés d'isochromène utiles en tant qu'inhibiteurs des phosphoinositide 3-kinases | |
MA47736B1 (fr) | Pyrimidopyrimidinones utiles en tant qu'inhibiteurs de la kinase wee-1 | |
FR3034993B1 (fr) | Conditionnement unitaire, compositions et schemas therapeutiques pour l'administration de stimulateurs des voies de pro-resolution sur des surfaces keratiniques | |
MA38287B1 (fr) | Nouveaux dérivés aminopyrazine pour le traitement ou la prévention du cancer | |
MA33457B1 (fr) | L-sérine pour son utilisation en tant que médicament pour prévenir et/ou traiter une réaction inflammatoire de la peau | |
TN2016000040A1 (fr) | Inhibiteurs de porc2 et procedes pour leur utilisation | |
MX2012005689A (es) | Analogos de acido araquidonico y metodos para el tratamiento analgesico utilizando los mismos. | |
GB2476446A (en) | Topical treatment of skin infection | |
EA201890906A1 (ru) | ПРОИЗВОДНЫЕ ХИНОКСАЛИНА И ПИРИДОПИРАЗИНА В КАЧЕСТВЕ ИНГИБИТОРОВ PI3Kβ | |
MA39253A1 (fr) | Composés hétéroaryle bicycliques substitués utilisés comme agonistes de rxr | |
EA201500737A1 (ru) | Пиразолилкарбоксамиды ii в качестве ингибиторов crac каналов | |
DE602006013826D1 (de) | Zusammensetzungen zur behandlung von systemischer mastocytose |