MA33894B1 - Procedes d'administration therapeutique de la pirferidone - Google Patents
Procedes d'administration therapeutique de la pirferidoneInfo
- Publication number
- MA33894B1 MA33894B1 MA35025A MA35025A MA33894B1 MA 33894 B1 MA33894 B1 MA 33894B1 MA 35025 A MA35025 A MA 35025A MA 35025 A MA35025 A MA 35025A MA 33894 B1 MA33894 B1 MA 33894B1
- Authority
- MA
- Morocco
- Prior art keywords
- perfridone
- treatment
- pirfenidone
- fluvoxamine
- moderate
- Prior art date
Links
- 206010013710 Drug interaction Diseases 0.000 abstract 1
- 239000002532 enzyme inhibitor Substances 0.000 abstract 1
- CJOFXWAVKWHTFT-XSFVSMFZSA-N fluvoxamine Chemical compound COCCCC\C(=N/OCCN)C1=CC=C(C(F)(F)F)C=C1 CJOFXWAVKWHTFT-XSFVSMFZSA-N 0.000 abstract 1
- 229960004038 fluvoxamine Drugs 0.000 abstract 1
- ISWRGOKTTBVCFA-UHFFFAOYSA-N pirfenidone Chemical compound C1=C(C)C=CC(=O)N1C1=CC=CC=C1 ISWRGOKTTBVCFA-UHFFFAOYSA-N 0.000 abstract 1
- 229960003073 pirfenidone Drugs 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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Abstract
La présente invention porte sur des procédés qui consistent à éviter des interactions médicamenteuses indésirables avec la fluvoxamine et la pirfénidone ou autres inhibiteurs modérés à puissants d'enzymes CYP.
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26681509P | 2009-12-04 | 2009-12-04 | |
| US12/684,879 US7816383B1 (en) | 2009-12-04 | 2010-01-08 | Methods of administering pirfenidone therapy |
| EP10250379A EP2324831B1 (fr) | 2009-12-04 | 2010-03-03 | Thérapie par la pirfénidone évitant la fluvoxamine |
| US31067910P | 2010-03-04 | 2010-03-04 | |
| CA2710358A CA2710358C (fr) | 2009-12-04 | 2010-08-17 | Procedes permettant d'administrer un traitement par la pirfenidone |
| PCT/US2010/058943 WO2011069094A1 (fr) | 2009-12-04 | 2010-12-03 | Procédés d'administration d'une thérapie à la pirfénidone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33894B1 true MA33894B1 (fr) | 2013-01-02 |
Family
ID=42941192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA35025A MA33894B1 (fr) | 2009-12-04 | 2010-12-03 | Procedes d'administration therapeutique de la pirferidone |
Country Status (35)
| Country | Link |
|---|---|
| US (13) | US7816383B1 (fr) |
| EP (4) | EP2324831B1 (fr) |
| JP (3) | JP2012532934A (fr) |
| KR (3) | KR20120097418A (fr) |
| CN (2) | CN105168210A (fr) |
| AP (1) | AP3155A (fr) |
| AT (1) | ATE526024T1 (fr) |
| AU (2) | AU2010212490B8 (fr) |
| BR (1) | BR112012014108A8 (fr) |
| CA (1) | CA2710358C (fr) |
| CR (1) | CR20120207A (fr) |
| CY (1) | CY1112077T1 (fr) |
| DK (1) | DK2324831T3 (fr) |
| EA (1) | EA035566B1 (fr) |
| ES (1) | ES2395155T3 (fr) |
| GE (1) | GEP20166455B (fr) |
| HK (1) | HK1217903A1 (fr) |
| HR (1) | HRP20110959T1 (fr) |
| IL (2) | IL219053B (fr) |
| MA (1) | MA33894B1 (fr) |
| MX (1) | MX2012004662A (fr) |
| MY (1) | MY184914A (fr) |
| NZ (1) | NZ599247A (fr) |
| PE (1) | PE20121502A1 (fr) |
| PH (1) | PH12012500733A1 (fr) |
| PL (2) | PL2324831T3 (fr) |
| PT (1) | PT2324831E (fr) |
| RS (1) | RS52102B (fr) |
| SG (2) | SG181129A1 (fr) |
| SI (1) | SI2324831T1 (fr) |
| SM (1) | SMT201200009B (fr) |
| TN (1) | TN2012000280A1 (fr) |
| TW (1) | TWI373465B (fr) |
| WO (1) | WO2011069094A1 (fr) |
| ZA (1) | ZA201202555B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7816383B1 (en) * | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
| US10105356B2 (en) | 2011-01-31 | 2018-10-23 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| CA2824432C (fr) | 2011-01-31 | 2021-10-19 | Genoa Pharmaceuticals, Inc. | Composes analogues de pyridone et de pirfenidone en aerosol, et leurs utilisations |
| EP2783016A1 (fr) * | 2011-11-22 | 2014-10-01 | Intermune, Inc. | Procédés de diagnostic et de traitement de la fibrose pulmonaire idiopathique |
| CA2819967C (fr) * | 2012-08-31 | 2016-03-22 | Intermune, Inc. | Utilisation de pirfenidone en simultanee avec du ciprofloxacin |
| CN103800325A (zh) * | 2012-11-12 | 2014-05-21 | 张康 | 吡非尼酮的新用途 |
| EP2968292A4 (fr) | 2013-03-15 | 2016-11-23 | Intermune Inc | Méthodes d'amélioration de l'intégrité microvasculaire |
| EP4491180A1 (fr) | 2014-01-10 | 2025-01-15 | Avalyn Pharma Inc. | Composés analogues de pirfénidone et de pyridone en aérosol et leurs utilisations |
| WO2016044153A1 (fr) * | 2014-09-18 | 2016-03-24 | Rush University Medical Center | Méthodes de prévention ou de traitement de l'arthrose |
| SI3325444T1 (sl) | 2015-07-20 | 2021-11-30 | Acadia Pharmaceuticals Inc. | Postopki za pripravo N-(4-fluorobenzil)-N-(1-metilpiperidin-4-il)-N'- (4-(2-metilpropiloksi)fenilmetil)karbamida in njegove tartratne soli in polimorfne oblike C |
| US10582726B2 (en) * | 2015-10-21 | 2020-03-10 | Rai Strategic Holdings, Inc. | Induction charging for an aerosol delivery device |
| WO2017165635A1 (fr) | 2016-03-25 | 2017-09-28 | Acadia Pharmaceuticals Inc. | Association de pimavansérine et de modulateurs du cytochrome p450 |
| US10953000B2 (en) | 2016-03-25 | 2021-03-23 | Acadia Pharmaceuticals Inc. | Combination of pimavanserin and cytochrome P450 modulators |
| CA2937365C (fr) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Formulation en granules de 5-methyl-1-phenyl-2-(1h)-pyridone et methode de fabrication associee |
| US11464768B2 (en) | 2016-12-20 | 2022-10-11 | Acadia Pharmaceuticals Inc. | Pimavanserin alone or in combination for use in the treatment of Alzheimer's disease psychosis |
| US11135211B2 (en) | 2017-04-28 | 2021-10-05 | Acadia Pharmaceuticals Inc. | Pimavanserin for treating impulse control disorder |
| US20220143011A1 (en) | 2017-05-16 | 2022-05-12 | Bow River LLC | Methods of treatment with cyp3a4 substrate drugs |
| US10857144B2 (en) | 2017-05-16 | 2020-12-08 | Bow River LLC | Methods of treatment |
| AU2017414697B2 (en) * | 2017-05-16 | 2020-03-05 | Bow River LLC | Methods of treatment |
| EP3675827A1 (fr) | 2017-08-30 | 2020-07-08 | Acadia Pharmaceuticals Inc. | Formulations de pimavansérine |
| US12480960B2 (en) | 2019-01-11 | 2025-11-25 | University Of Virginia Patent Foundation | Compositions and methods for predicting lung function decline in idiopathic pulmonary fibrosis |
| WO2021057599A1 (fr) * | 2019-09-26 | 2021-04-01 | 深圳先进技术研究院 | Application de pirfénidone dans la préparation d'un médicament pour la prévention et le traitement de la polyarthrite rhumatoïde |
| CA3160410A1 (fr) | 2019-12-04 | 2021-06-10 | Idorsia Pharmaceuticals Ltd | Combinaison d'un antagoniste du recepteur lpa1 de l'azetidine avec de la pirfenidone et/ou du nintedanib destinee a etre utilisee dans le traitement de maladies fibrotiques |
| WO2021252951A1 (fr) | 2020-06-12 | 2021-12-16 | Vanderbilt University | Méthodes de traitement de troubles de motilité gastro-intestinale |
| CA3198246A1 (fr) * | 2020-11-12 | 2022-05-19 | Pharvaris Gmbh | Prophylaxie et traitement de l??deme de quincke |
| WO2023161668A1 (fr) | 2022-02-28 | 2023-08-31 | Nuformix Technologies Limited | Compositions et méthodes de traitement de la fibrose pulmonaire idiopathique |
| CN115282151B (zh) * | 2022-08-23 | 2023-06-09 | 黑龙江护理高等专科学校 | 一种拉米替隆的应用 |
| GB2628348A (en) * | 2023-03-20 | 2024-09-25 | Ontrack Therapeutics Ltd | Amelioration of drug-drug interactions |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02215719A (ja) * | 1989-02-15 | 1990-08-28 | Yamauchi Akitomo | 線維化病変組織の修復並びに線維化病変の阻止剤 |
| US5310562A (en) | 1989-11-22 | 1994-05-10 | Margolin Solomon B | Composition and method for reparation and prevention of fibrotic lesions |
| US5518729A (en) | 1989-11-22 | 1996-05-21 | Margolin; Solomon B. | Compositions and methods for reparation and prevention of fibrotic lesions |
| US5716632A (en) | 1989-11-22 | 1998-02-10 | Margolin; Solomon B. | Compositions and methods for reparation and prevention of fibrotic lesions |
| WO1998014169A1 (fr) | 1996-09-30 | 1998-04-09 | Brigham & Women's Hospital | Methodes et composes destines au traitement de l'hemorragie uterine anormale |
| JP2006502152A (ja) | 2002-08-28 | 2006-01-19 | インターミューン インコーポレイテッド | 線維性疾患治療用の併用療法 |
| JP4542743B2 (ja) * | 2002-12-26 | 2010-09-15 | Kdl株式会社 | ピリドン誘導体の溶液状医薬組成物 |
| US20070072181A1 (en) | 2003-02-28 | 2007-03-29 | Blatt Lawrence M | Combination therapy for treating alphavirus infection and liver fibrosis |
| WO2004103296A2 (fr) | 2003-05-16 | 2004-12-02 | Intermune, Inc. | Methodes de traitement d'une fibrose pulmonaire idiopathique |
| EP1633317A4 (fr) | 2003-05-16 | 2008-08-20 | Intermune Inc | Ligands des recepteurs des chimiokines synthetiques et leurs methodes d'utilisation |
| US20070053877A1 (en) | 2003-08-21 | 2007-03-08 | Intermune, Inc. | Methods of treating idiopathic pulmonary fibrosis |
| WO2005040758A2 (fr) | 2003-10-24 | 2005-05-06 | Intermune, Inc. | Utilisation de pirfenidone dans des posologies therapeutiques |
| CN1846699A (zh) | 2005-04-13 | 2006-10-18 | 中南大学湘雅医院 | 1-(取代苯基)-5-甲基-2-(1h) 吡啶酮(i)化合物用于制备抗除肾间质纤维化外其他器官纤维化或组织纤维化药物的应用 |
| RS53599B1 (sr) | 2005-05-10 | 2015-02-27 | Intermune, Inc. | Piridon derivati za modulaciju stresom aktiviranog sistema proteinskih kinaza |
| KR101294467B1 (ko) | 2005-07-25 | 2013-09-09 | 인터뮨, 인크. | C형 간염 바이러스 복제의 신규 거대고리형 억제제 |
| NZ591443A (en) | 2005-09-22 | 2013-04-26 | Intermune Inc | Granule formation of pirfenidone and pharmaceutically acceptable excipients |
| ATE551057T1 (de) | 2005-10-31 | 2012-04-15 | Intermune Inc | Zusammensetzungen von pirfenidon/toll-like rezeptor (tlr)-antagonisten und verfahren zu ihrer verwendung zur stimulierung der produktion des granulozyten-kolonie-stimulierenden faktors (g-csf) |
| US20070203202A1 (en) | 2005-12-02 | 2007-08-30 | Robinson Cynthia Y | Methods of reducing adverse events associated with pirfenidone therapy |
| US20080003635A1 (en) | 2006-06-12 | 2008-01-03 | Intermune, Inc. | High Throughput Collagen Synthesis Assay |
| RU2008152171A (ru) | 2006-07-05 | 2010-08-10 | Интермьюн, Инк. (Us) | Новые ингибиторы вирусной репликации гепатита с |
| EP2338489B1 (fr) | 2006-12-18 | 2016-04-27 | InterMune, Inc. | Procédé permettant d'administrer une thérapie par le pirfenidone à un patient |
| US20080287508A1 (en) | 2007-05-18 | 2008-11-20 | Intermune, Inc. | Altering pharmacokinetics of pirfenidone therapy |
| US20090131485A1 (en) | 2007-09-10 | 2009-05-21 | Concert Pharmaceuticals, Inc. | Deuterated pirfenidone |
| JP5627574B2 (ja) | 2008-06-03 | 2014-11-19 | インターミューン, インコーポレイテッド | 炎症性および線維性疾患を治療するための化合物および方法 |
| US7566729B1 (en) | 2008-11-10 | 2009-07-28 | Intermune, Inc. | Modifying pirfenidone treatment for patients with atypical liver function |
| US7635707B1 (en) | 2008-11-10 | 2009-12-22 | Intermune, Inc. | Pirfenidone treatment for patients with atypical liver function |
| US8084475B2 (en) | 2009-12-04 | 2011-12-27 | Intermune, Inc. | Pirfenidone therapy and inducers of cytochrome P450 |
| US7816383B1 (en) | 2009-12-04 | 2010-10-19 | Intermune, Inc. | Methods of administering pirfenidone therapy |
| CA2819967C (fr) | 2012-08-31 | 2016-03-22 | Intermune, Inc. | Utilisation de pirfenidone en simultanee avec du ciprofloxacin |
| US9621933B2 (en) | 2015-03-27 | 2017-04-11 | Ericsson Ab | System and method for providing VOD content in a switched digital video network using unicast ABR streaming |
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- 2010-03-03 DK DK10250379.4T patent/DK2324831T3/da active
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