MA33767B1 - Nouvelle utilisation anticancéreuse du cabazitaxel - Google Patents
Nouvelle utilisation anticancéreuse du cabazitaxelInfo
- Publication number
- MA33767B1 MA33767B1 MA34898A MA34898A MA33767B1 MA 33767 B1 MA33767 B1 MA 33767B1 MA 34898 A MA34898 A MA 34898A MA 34898 A MA34898 A MA 34898A MA 33767 B1 MA33767 B1 MA 33767B1
- Authority
- MA
- Morocco
- Prior art keywords
- cabazitaxel
- new anticancer
- anticancer use
- treatment
- cancer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Psychology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
Abstract
L'invention concerne un composé de formule (I) pouvant se présenter sous la forme d'une base ou d'un hydrate ou d'un solvate, en combinaison avec prednisone ou prednisolone, pour être utilisé comme médicament dans le traitement du cancer de la prostate, en particulier le cancer métastasique de la prostate, spécialement pour des patients qui ne sont pas soumis à un traitement à base de taxane.
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25616009P | 2009-10-29 | 2009-10-29 | |
US29390310P | 2010-01-11 | 2010-01-11 | |
US35588810P | 2010-06-17 | 2010-06-17 | |
US35583410P | 2010-06-17 | 2010-06-17 | |
US36992910P | 2010-08-02 | 2010-08-02 | |
US38393310P | 2010-09-17 | 2010-09-17 | |
US38996910P | 2010-10-05 | 2010-10-05 | |
PCT/IB2010/054866 WO2011051894A1 (fr) | 2009-10-29 | 2010-10-27 | Nouvelle utilisation antitumorale du cabazitaxel |
Publications (1)
Publication Number | Publication Date |
---|---|
MA33767B1 true MA33767B1 (fr) | 2012-11-01 |
Family
ID=43567614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA34898A MA33767B1 (fr) | 2009-10-29 | 2012-05-25 | Nouvelle utilisation anticancéreuse du cabazitaxel |
Country Status (30)
Country | Link |
---|---|
US (8) | US8927592B2 (fr) |
EP (1) | EP2493466B1 (fr) |
JP (2) | JP5566466B2 (fr) |
KR (1) | KR101712231B1 (fr) |
CN (1) | CN102770131A (fr) |
AR (1) | AR078824A1 (fr) |
AU (4) | AU2010310986A1 (fr) |
BR (1) | BR112012011457A2 (fr) |
CA (1) | CA2779009A1 (fr) |
CR (1) | CR20120204A (fr) |
DK (1) | DK2493466T3 (fr) |
EA (1) | EA024186B1 (fr) |
EC (1) | ECSP12011836A (fr) |
ES (1) | ES2862340T3 (fr) |
GT (1) | GT201200123A (fr) |
IL (3) | IL219443A0 (fr) |
MA (1) | MA33767B1 (fr) |
MX (1) | MX336339B (fr) |
MY (1) | MY164086A (fr) |
NI (1) | NI201200071A (fr) |
PE (1) | PE20121429A1 (fr) |
PL (1) | PL2493466T3 (fr) |
PT (1) | PT2493466T (fr) |
SG (1) | SG10201810928SA (fr) |
SV (1) | SV2012004192A (fr) |
TN (1) | TN2012000188A1 (fr) |
TW (2) | TWI654975B (fr) |
UY (1) | UY32987A (fr) |
WO (1) | WO2011051894A1 (fr) |
ZA (1) | ZA201203123B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2926551A1 (fr) | 2008-01-17 | 2009-07-24 | Aventis Pharma Sa | Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation |
US20120065255A1 (en) * | 2009-10-19 | 2012-03-15 | Nagesh Palepu | Cabazitaxel formulations and methods of preparing thereof |
AU2010310986A1 (en) | 2009-10-29 | 2012-06-14 | Aventis Pharma S.A. | Novel antitumoral use of cabazitaxel |
JP2014514306A (ja) * | 2011-04-12 | 2014-06-19 | プラス・ケミカルス・エスアー | 固体形態のカバジタキセル及びその製造方法 |
CN102503913B (zh) * | 2011-10-20 | 2014-03-26 | 江苏红豆杉生物科技股份有限公司 | 直接用于x射线单晶衍射分析的二甲氧基紫杉烷类化合物单晶晶体的制备方法 |
WO2013088335A1 (fr) | 2011-12-13 | 2013-06-20 | Aventis Pharma S.A. | Forme cristalline de cabazitaxel et procédé pour préparer celle-ci |
US9403785B2 (en) * | 2012-01-03 | 2016-08-02 | Shilpa Medicare Limited | Process for preparing amorphous cabazitaxel |
CN104583189A (zh) | 2012-07-31 | 2015-04-29 | 永信药品工业股份有限公司 | 非晶型的卡巴利他索 |
TW201438714A (zh) * | 2013-03-04 | 2014-10-16 | Aventis Pharma Sa | 卡巴他賽(cabazitaxel)及其治療轉移性前列腺癌之用途 |
EP2815749A1 (fr) | 2013-06-20 | 2014-12-24 | IP Gesellschaft für Management mbH | Forme solide de 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione ayant un réseau de diffraction de rayons X spécifique |
PL3258931T3 (pl) | 2015-02-17 | 2020-12-28 | Erasmus University Medical Center Rotterdam | Zastosowanie kabazitakselu w leczeniu nowotworu złośliwego prostaty |
EP3093014A1 (fr) * | 2015-05-13 | 2016-11-16 | Aventis Pharma S.A. | Cabazitaxel et son utilisation pour le traitement du cancer |
US20190224332A1 (en) | 2016-09-07 | 2019-07-25 | Cadila Healthcare Limited | Sterile injectable compositions comprising drug micelles |
US20170281651A1 (en) | 2017-03-01 | 2017-10-05 | Corcept Therapeutics, Inc. | Concomitant administration of glucocorticoid receptor modulators and cyp3a or steroidogenesis inhibitors |
WO2018187786A1 (fr) * | 2017-04-07 | 2018-10-11 | La Jolla Institute For Allergy And Immunology | Cellules unipotentes progénitrices de neutrophiles, procédés de préparation et utilisations associées |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5005588A (en) | 1989-10-13 | 1991-04-09 | David Rubin | Method for increasing tumor sensitivity to chemotherapy |
US5698582A (en) | 1991-07-08 | 1997-12-16 | Rhone-Poulenc Rorer S.A. | Compositions containing taxane derivatives |
US5714512A (en) | 1991-07-08 | 1998-02-03 | Rhone-Poulenc Rorer, S.A. | Compositions containing taxane derivatives |
US5750561A (en) | 1991-07-08 | 1998-05-12 | Rhone-Poulenc Rorer, S.A. | Compositions containing taxane derivatives |
FR2698543B1 (fr) | 1992-12-02 | 1994-12-30 | Rhone Poulenc Rorer Sa | Nouvelles compositions à base de taxoides. |
FR2698871B1 (fr) | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
ZA94128B (en) | 1993-02-01 | 1994-08-19 | Univ New York State Res Found | Process for the preparation of taxane derivatives and betalactam intermediates therefor |
FR2732340B1 (fr) | 1995-03-27 | 1997-04-30 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
MA23823A1 (fr) | 1995-03-27 | 1996-10-01 | Aventis Pharma Sa | Nouveaux taxoides, leur preparation et les compositions qui les contiennent |
US6372780B2 (en) | 1995-03-27 | 2002-04-16 | Aventis Pharma S.A. | Methods of treating cell lines expressing multidrug resistance P-glycoprotein |
US5847170A (en) | 1995-03-27 | 1998-12-08 | Rhone-Poulenc Rorer, S.A. | Taxoids, their preparation and pharmaceutical compositions containing them |
FR2745814B1 (fr) | 1996-03-06 | 1998-04-03 | Rhone Poulenc Rorer Sa | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2771092B1 (fr) | 1997-11-18 | 1999-12-17 | Rhone Poulenc Rorer Sa | Procede de preparation de derives de la classe des taxoides |
US6346543B1 (en) | 1998-08-17 | 2002-02-12 | Aventis Pharma S.A. | Use of a taxoid to treat abnormal cell proliferation in the brain |
IL141231A0 (en) | 1998-08-20 | 2002-03-10 | Aventis Pharma Sa | New use of taxoid derivatives |
US6403634B1 (en) | 1999-01-13 | 2002-06-11 | Aventis Pharma S.A. | Use of taxoid derivatives |
US20040126379A1 (en) | 2002-08-21 | 2004-07-01 | Boehringer Ingelheim International Gmbh | Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents |
SI1493556T1 (sl) | 2003-07-02 | 2006-02-28 | Scheuten Glasgroep Bv | Postopek za pripravo protipozarne zasteklitve |
EP1498120A1 (fr) | 2003-07-18 | 2005-01-19 | Aventis Pharma S.A. | Formulation semi-solide pour l'administration orale du taxol |
FR2859996B1 (fr) * | 2003-09-19 | 2006-02-03 | Aventis Pharma Sa | Solvat acetonique du dimethoxy docetaxel et son procede de preparation |
GB0425854D0 (en) | 2004-11-25 | 2004-12-29 | Astrazeneca Ab | Therapeutic treatment |
JP5139811B2 (ja) | 2004-12-08 | 2013-02-06 | アベンティス・ファーマスーティカルズ・インコーポレイテツド | ドセタキセル耐性または感受性の測定方法 |
EP1700596A1 (fr) | 2005-03-09 | 2006-09-13 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Utilisation de composés stabilisant les microtubules pour le traitement des lesions axonales du SNC |
FR2922107B1 (fr) | 2007-10-10 | 2010-02-26 | Aventis Pharma Sa | Nouvelles compositions a base de taxoides |
FR2926551A1 (fr) | 2008-01-17 | 2009-07-24 | Aventis Pharma Sa | Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation |
EP2177630A1 (fr) | 2008-10-02 | 2010-04-21 | Institut Gustave Roussy | Procédés de prédiction ou de suivi du fait qu'un patient atteint d'un cancer répond à une traitement par une molécule de la famille des taxoïdes |
US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
AU2010234916A1 (en) | 2009-03-30 | 2011-10-13 | Cerulean Pharma Inc. | Polymer-agent conjugates, particles, compositions, and related methods of use |
FR2945211A1 (fr) | 2009-05-06 | 2010-11-12 | Sanofi Aventis | Combinaison antitumorale comprenant la cabazitaxel et la capecitabine |
MX366955B (es) | 2009-09-15 | 2019-07-31 | Bluelink Pharmaceuticals Inc | Crlx101 para usarse en el tratamiento de cáncer. |
US7772274B1 (en) | 2009-10-19 | 2010-08-10 | Scidose, Llc | Docetaxel formulations with lipoic acid |
AU2010310986A1 (en) | 2009-10-29 | 2012-06-14 | Aventis Pharma S.A. | Novel antitumoral use of cabazitaxel |
ES2621613T3 (es) | 2009-11-04 | 2017-07-04 | Emcure Pharmaceuticals Limited | Un proceso mejorado para la preparación de derivados de taxano |
CN104208716A (zh) | 2009-11-23 | 2014-12-17 | 天蓝制药公司 | 用于传递治疗剂的基于环糊精的聚合物 |
US20130130928A1 (en) | 2010-04-08 | 2013-05-23 | Institut Gustave Roussy | Methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family |
WO2011130317A2 (fr) | 2010-04-13 | 2011-10-20 | Amplyx Pharmaceuticals Inc. | Agents thérapeutiques ayant une toxicité réduite |
JP5975983B2 (ja) | 2010-04-16 | 2016-08-23 | ベリカム ファーマシューティカルズ, インコーポレイテッド | 固形腫瘍を処置するための方法 |
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2010
- 2010-10-27 AU AU2010310986A patent/AU2010310986A1/en not_active Abandoned
- 2010-10-27 EA EA201270606A patent/EA024186B1/ru not_active IP Right Cessation
- 2010-10-27 EP EP10782039.1A patent/EP2493466B1/fr active Active
- 2010-10-27 CN CN2010800600528A patent/CN102770131A/zh active Pending
- 2010-10-27 SG SG10201810928SA patent/SG10201810928SA/en unknown
- 2010-10-27 PE PE2012000581A patent/PE20121429A1/es not_active Application Discontinuation
- 2010-10-27 KR KR1020127013564A patent/KR101712231B1/ko active IP Right Grant
- 2010-10-27 WO PCT/IB2010/054866 patent/WO2011051894A1/fr active Application Filing
- 2010-10-27 JP JP2012535996A patent/JP5566466B2/ja active Active
- 2010-10-27 BR BR112012011457A patent/BR112012011457A2/pt not_active Application Discontinuation
- 2010-10-27 PL PL10782039T patent/PL2493466T3/pl unknown
- 2010-10-27 MX MX2012005030A patent/MX336339B/es unknown
- 2010-10-27 PT PT107820391T patent/PT2493466T/pt unknown
- 2010-10-27 DK DK10782039.1T patent/DK2493466T3/da active
- 2010-10-27 MY MYPI2012001871A patent/MY164086A/en unknown
- 2010-10-27 CA CA2779009A patent/CA2779009A1/fr not_active Abandoned
- 2010-10-27 ES ES10782039T patent/ES2862340T3/es active Active
- 2010-10-29 AR ARP100103990 patent/AR078824A1/es unknown
- 2010-10-29 TW TW104143630A patent/TWI654975B/zh active
- 2010-10-29 UY UY32987A patent/UY32987A/es unknown
- 2010-10-29 TW TW099137327A patent/TWI533866B/zh active
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2012
- 2012-04-25 IL IL219443A patent/IL219443A0/en unknown
- 2012-04-25 TN TNP2012000188A patent/TN2012000188A1/en unknown
- 2012-04-25 CR CR20120204A patent/CR20120204A/es unknown
- 2012-04-26 US US13/456,720 patent/US8927592B2/en active Active
- 2012-04-26 GT GT201200123A patent/GT201200123A/es unknown
- 2012-04-27 SV SV2012004192A patent/SV2012004192A/es unknown
- 2012-04-27 NI NI201200071A patent/NI201200071A/es unknown
- 2012-04-27 EC ECSP12011836 patent/ECSP12011836A/es unknown
- 2012-04-30 ZA ZA2012/03123A patent/ZA201203123B/en unknown
- 2012-05-25 MA MA34898A patent/MA33767B1/fr unknown
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2014
- 2014-06-16 JP JP2014123108A patent/JP6182510B2/ja active Active
- 2014-12-18 US US14/575,578 patent/US20150118182A1/en not_active Abandoned
- 2014-12-18 US US14/575,566 patent/US20150104411A1/en not_active Abandoned
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2016
- 2016-02-01 AU AU2016200598A patent/AU2016200598A1/en not_active Abandoned
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2017
- 2017-01-24 IL IL250254A patent/IL250254A0/en unknown
- 2017-06-20 US US15/627,962 patent/US10583110B2/en active Active
- 2017-09-25 AU AU2017232227A patent/AU2017232227B2/en not_active Ceased
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2019
- 2019-01-18 US US16/251,143 patent/US20190151278A1/en not_active Abandoned
- 2019-05-20 AU AU2019203514A patent/AU2019203514A1/en not_active Abandoned
- 2019-06-23 IL IL267583A patent/IL267583A/en unknown
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2020
- 2020-01-15 US US16/743,411 patent/US10716777B2/en active Active
- 2020-07-17 US US16/931,802 patent/US20210169843A1/en not_active Abandoned
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2023
- 2023-07-20 US US18/224,122 patent/US20240139146A1/en active Pending
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