MA32932B1 - Inhibiteurs de hsp90 utiles dans un traitement therapeutique - Google Patents

Inhibiteurs de hsp90 utiles dans un traitement therapeutique

Info

Publication number
MA32932B1
MA32932B1 MA33956A MA33956A MA32932B1 MA 32932 B1 MA32932 B1 MA 32932B1 MA 33956 A MA33956 A MA 33956A MA 33956 A MA33956 A MA 33956A MA 32932 B1 MA32932 B1 MA 32932B1
Authority
MA
Morocco
Prior art keywords
treatment
useful
hsp90 inhibitors
syndrome
castleman
Prior art date
Application number
MA33956A
Other languages
Arabic (ar)
English (en)
Inventor
Carlos Garcia-Echeverria
Michael Rugaard Jensen
Cornelia Quadt
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40139942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32932(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA32932B1 publication Critical patent/MA32932B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Abstract

L'invention concerne l'utilisation d'un inhibiteur de Hsp90 dans le traitement du cancer de la vessie, du colon, du foie, du poumon, du sein, du vagin, des ovaires, du pancréas, du rein, de l'estomac, du tractus gastro-intestinal, de la prostate, de la tête et du cou, de la cavité péritonéale, de la thyroïde, des os, du cerveau, du système nerveux central et/ou de la leucémie et/ou dans le traitement du syndrome myélodysplasique, de la mastocytose systémique, du syndrome de Von Hippel-Lindau, de la maladie de Castleman multicentrique et/ou du psoriasis.
MA33956A 2008-11-28 2009-11-25 Inhibiteurs de hsp90 utiles dans un traitement therapeutique MA32932B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08170284 2008-11-28
PCT/EP2009/065862 WO2010060940A2 (fr) 2008-11-28 2009-11-25 Inhibiteurs de hsp90 utiles dans un traitement therapeutique

Publications (1)

Publication Number Publication Date
MA32932B1 true MA32932B1 (fr) 2012-01-02

Family

ID=40139942

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33956A MA32932B1 (fr) 2008-11-28 2009-11-25 Inhibiteurs de hsp90 utiles dans un traitement therapeutique

Country Status (16)

Country Link
US (2) US20110230499A1 (fr)
EP (2) EP2572709A1 (fr)
JP (1) JP2012510444A (fr)
KR (1) KR20110097907A (fr)
CN (1) CN102227220A (fr)
AU (1) AU2009319051A1 (fr)
BR (1) BRPI0924107A2 (fr)
CA (1) CA2743722A1 (fr)
IL (1) IL212924A0 (fr)
MA (1) MA32932B1 (fr)
MX (1) MX2011005664A (fr)
RU (1) RU2011126254A (fr)
TN (1) TN2011000240A1 (fr)
TW (1) TW201024295A (fr)
WO (1) WO2010060940A2 (fr)
ZA (1) ZA201103576B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014008400A2 (pt) * 2011-10-14 2017-04-04 Novartis Ag derivados de 2-carboxamida cicloamino ureia em combinação com os inibidores de hsp90 para o tratamento de doenças proliferativas
AU2014228822A1 (en) 2013-03-15 2015-10-01 Memorial Sloan-Kettering Cancer Center HSP90-targeted cardiac imaging and therapy
GB201306610D0 (en) * 2013-04-11 2013-05-29 Almac Discovery Ltd Pharmaceutical compounds
WO2015090224A1 (fr) 2013-12-20 2015-06-25 中国人民解放军军事医学科学院毒物药物研究所 Nouveau composé pipéridine carboxamide, procédé de préparation et utilisation associée
CA2961499A1 (fr) 2014-09-17 2016-03-24 Memorial Sloan Kettering Cancer Center Imagerie et therapie d'une inflammation et d'une infection ciblant hsp90
HUE062076T2 (hu) 2017-12-21 2023-09-28 Boehringer Ingelheim Int Benzilamino-szubsztituált piridopirimidinonok és származékai mint sos1
CN116789671A (zh) * 2022-03-22 2023-09-22 上海维申医药有限公司 作为Toll样受体激动剂的嘧啶并哒嗪酮类化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946456B2 (en) * 2000-07-28 2005-09-20 Sloan-Kettering Institute For Cancer Research Methods for treating cell proliferative disorders and viral infections
JO2783B1 (en) * 2005-09-30 2014-03-15 نوفارتيس ايه جي Compounds 2-Amino-7, 8-dihydro-6H-Bayredo (3,4-D) Pyrimidine-5-Ones
CN102227221A (zh) * 2008-11-28 2011-10-26 诺瓦提斯公司 包含hsp90抑制剂和mtor抑制剂的药物组合

Also Published As

Publication number Publication date
WO2010060940A3 (fr) 2010-08-26
MX2011005664A (es) 2011-06-16
TW201024295A (en) 2010-07-01
US20110230499A1 (en) 2011-09-22
CN102227220A (zh) 2011-10-26
CA2743722A1 (fr) 2010-06-03
WO2010060940A2 (fr) 2010-06-03
JP2012510444A (ja) 2012-05-10
US20130045983A1 (en) 2013-02-21
IL212924A0 (en) 2011-07-31
TN2011000240A1 (en) 2012-12-17
EP2370079A2 (fr) 2011-10-05
RU2011126254A (ru) 2013-01-10
EP2572709A1 (fr) 2013-03-27
ZA201103576B (en) 2012-01-25
KR20110097907A (ko) 2011-08-31
BRPI0924107A2 (pt) 2019-09-24
AU2009319051A1 (en) 2010-06-03

Similar Documents

Publication Publication Date Title
MA32932B1 (fr) Inhibiteurs de hsp90 utiles dans un traitement therapeutique
HK1254663A1 (zh) 用於實體腫瘤的治療的布魯頓酪氨酸激酶的抑制劑
CY2017013I2 (el) ΑΝΤΙΣΩΜΑ ΕΝΑΝΤΙΟΝ PDGFR-α ΓΙΑ ΧΡΗΣΗ ΣΤΗΝ ΘΕΡΑΠΕΥΤΙΚΗ ΑΓΩΓΗ ΟΓΚΩΝ
JP2010507577A5 (fr)
MY163477A (en) Pyrimidinyl-pyridazinone derivatives
MY153198A (en) Inhibitors of protein aggregation
UA100540C2 (en) 2-benzylpyridazinone derivatives as met kinase inhibitors
EA200901611A1 (ru) Производные 2-оксо-3-бензил-бензоксазол-2-она и родственные соединения в качестве ингибиторов мет киназы для лечения опухолей
MY159230A (en) P38 map kinase inhibitors
WO2009105513A3 (fr) Nouveaux composés et procédés pour la thérapie
UA104731C2 (ru) Ингибиторы р38 мар-киназ
EA200901601A1 (ru) Производные пиридазинона
MX2010003368A (es) Derivados de imidazol.
EA200801430A1 (ru) Производные триазола
EA201100334A1 (ru) Бициклические производные триазола для лечения опухолей
PL2259800T3 (pl) Zastosowanie 5-(2,6-dimorfolin-4-ylopirymidyn-4-ylo)-4-trifluorometylopirydyn-2-yloaminy do leczenia niedrobnokomórkowego raka płuca wykazującego nabytą oporność wobec modulatorów receptora dla naskórkowego czynnika wzrostu (EGFR)
NO20071613L (no) Forbindelser for myokardial perfusjons-billeddannelse
NO20084892L (no) C-kit kinase inhibitor for anvendelse i terapeutisk behandling av gastrointestinal stromaltumor eller mastocytose.
MX2009010269A (es) Metodos de tratamiento del cancer mediante administracion de combinaciones de interleucina-18 humana.
EA200901179A1 (ru) Замещённые тетрагидрохинолины
MX2010004259A (es) Tratamientos antitumorales mejorados.
EA200971067A1 (ru) Триазолиламинопиримидиновые соединения
WO2009074253A3 (fr) Dérivés de phospholipide de clofarabine
MX2009011388A (es) Inhibidores de polimerasa y su uso para el tratamiento de tumores.
DK2155179T3 (da) Axomadol til smertebehandling arthrose