MA32806B1 - Thérapie de combinaison avec des peptides époxycétones - Google Patents

Thérapie de combinaison avec des peptides époxycétones

Info

Publication number
MA32806B1
MA32806B1 MA33861A MA33861A MA32806B1 MA 32806 B1 MA32806 B1 MA 32806B1 MA 33861 A MA33861 A MA 33861A MA 33861 A MA33861 A MA 33861A MA 32806 B1 MA32806 B1 MA 32806B1
Authority
MA
Morocco
Prior art keywords
peptides
epoxycitones
structure therapy
relates
epoxyketone
Prior art date
Application number
MA33861A
Other languages
Arabic (ar)
English (en)
Inventor
Christopher J Kirk
Susan D Demo
Mark K Bennett
Original Assignee
Onyx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42119657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA32806(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Onyx Therapeutics Inc filed Critical Onyx Therapeutics Inc
Publication of MA32806B1 publication Critical patent/MA32806B1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Organic Chemistry (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
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Abstract

La présente invention concerne une thérapie de combinaison, un ou plusieurs agents thérapeutiques étant administrés avec des peptides époxycétones ou un sel pharmaceutiquement acceptable de ceux-ci. Un autre aspect de l'invention concerne le traitement du cancer avec un peptide époxycétone administré en combinaison avec un autre agent thérapeutique.
MA33861A 2008-10-21 2011-05-19 Thérapie de combinaison avec des peptides époxycétones MA32806B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19694508P 2008-10-21 2008-10-21
PCT/US2009/061498 WO2010048298A1 (fr) 2008-10-21 2009-10-21 Thérapie de combinaison avec des peptides époxycétones

Publications (1)

Publication Number Publication Date
MA32806B1 true MA32806B1 (fr) 2011-11-01

Family

ID=42119657

Family Applications (1)

Application Number Title Priority Date Filing Date
MA33861A MA32806B1 (fr) 2008-10-21 2011-05-19 Thérapie de combinaison avec des peptides époxycétones

Country Status (27)

Country Link
US (5) US20110236428A1 (fr)
EP (3) EP3090737A1 (fr)
JP (4) JP5675629B2 (fr)
KR (1) KR20110073584A (fr)
CN (1) CN102256616A (fr)
AP (1) AP2011005690A0 (fr)
AU (4) AU2009308516B2 (fr)
BR (1) BRPI0919668A2 (fr)
CA (1) CA2741312C (fr)
CL (1) CL2011000916A1 (fr)
CO (1) CO6361942A2 (fr)
CR (1) CR20110221A (fr)
DO (1) DOP2011000108A (fr)
EA (2) EA024364B1 (fr)
EC (1) ECSP11011027A (fr)
ES (1) ES2617560T3 (fr)
HK (1) HK1202436A1 (fr)
IL (1) IL212506A0 (fr)
MA (1) MA32806B1 (fr)
ME (1) ME01133B (fr)
MX (2) MX2011004225A (fr)
NI (1) NI201100077A (fr)
PE (1) PE20120059A1 (fr)
TN (1) TN2011000200A1 (fr)
UA (1) UA104600C2 (fr)
WO (1) WO2010048298A1 (fr)
ZA (1) ZA201103493B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1745064E (pt) 2004-04-15 2011-03-23 Proteolix Inc Compostos para a inibição de uma enzima de proteassoma
US8198270B2 (en) 2004-04-15 2012-06-12 Onyx Therapeutics, Inc. Compounds for proteasome enzyme inhibition
DK2623113T3 (en) 2005-11-09 2017-07-17 Onyx Therapeutics Inc Enzyme inhibition compound
US7691852B2 (en) 2006-06-19 2010-04-06 Onyx Therapeutics, Inc. Compounds for enzyme inhibition
DK2207791T4 (da) 2007-10-04 2019-10-07 Onyx Therapeutics Inc Krystallinske peptidepoxyketon-proteasehæmmere og syntese af aminosyreketoepoxider
ES2617560T3 (es) 2008-10-21 2017-06-19 Onyx Therapeutics, Inc. Combinación del inhibidor del proteasoma de epoxicetona peptídica carfilzomib con melfalán para su uso en el tratamiento del mieloma múltiple
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