MA29600B1 - Utilisation de sanglifehrine dans le virus de l'hepatite c - Google Patents

Utilisation de sanglifehrine dans le virus de l'hepatite c

Info

Publication number
MA29600B1
MA29600B1 MA30507A MA30507A MA29600B1 MA 29600 B1 MA29600 B1 MA 29600B1 MA 30507 A MA30507 A MA 30507A MA 30507 A MA30507 A MA 30507A MA 29600 B1 MA29600 B1 MA 29600B1
Authority
MA
Morocco
Prior art keywords
hepatitis
sanglifehrin
virus
hepatic
bloodlifetin
Prior art date
Application number
MA30507A
Other languages
English (en)
Inventor
Kai Lin
Beat Weidmann
Kaspar Zimmermann
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37075234&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA29600(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MA29600B1 publication Critical patent/MA29600B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention décrit l'utilisation d'un composé macrolide tel qu'une sangliféhrine pour le traitement et la prévention de l'hépatite C et de maladies s'y rapportant telles que la fibrose hépatique, la cirrhose hépatique et le carcinome hépatocellulaire.
MA30507A 2005-06-17 2007-12-26 Utilisation de sanglifehrine dans le virus de l'hepatite c MA29600B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69149705P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
MA29600B1 true MA29600B1 (fr) 2008-07-01

Family

ID=37075234

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30507A MA29600B1 (fr) 2005-06-17 2007-12-26 Utilisation de sanglifehrine dans le virus de l'hepatite c

Country Status (21)

Country Link
US (1) US20090221598A1 (fr)
EP (1) EP1893211B1 (fr)
JP (1) JP2008546708A (fr)
KR (1) KR20080033274A (fr)
CN (1) CN101242842A (fr)
AR (1) AR054778A1 (fr)
AT (1) ATE524183T1 (fr)
AU (1) AU2006259348B2 (fr)
BR (1) BRPI0613142A2 (fr)
CA (1) CA2611151A1 (fr)
EC (1) ECSP078029A (fr)
GT (1) GT200600262A (fr)
MA (1) MA29600B1 (fr)
MX (1) MX2007016068A (fr)
NO (1) NO20080351L (fr)
PE (1) PE20070118A1 (fr)
RU (1) RU2427372C2 (fr)
TN (1) TNSN07477A1 (fr)
TW (1) TW200740438A (fr)
WO (1) WO2006138507A1 (fr)
ZA (1) ZA200710551B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102224242B (zh) * 2008-09-24 2014-09-24 中国科学院上海有机化学研究所 新基因簇
WO2011011632A1 (fr) * 2009-07-22 2011-01-27 Tufts University Procédés et compositions destinés à moduler le potentiel membranaire afin d'influencer le comportement de la cellule
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
EP2533784B1 (fr) 2010-02-09 2015-04-22 Neurovive Pharmaceutical AB Composés à base de sanglifehrin
WO2011098805A1 (fr) 2010-02-09 2011-08-18 Biotica Technology Limited Composés à base de sangliféhrine
WO2011098808A1 (fr) 2010-02-09 2011-08-18 Biotica Technology Limited Composés à base de sangliféhrine
GB201008123D0 (en) 2010-05-17 2010-06-30 Biotica Tech Ltd Novel compounds
UY33775A (es) * 2010-12-10 2012-07-31 Gilead Sciences Inc Inhibidores macrocíclicos de virus flaviviridae, composiciones farmacéuticas que los comprenden y sus usos
EP3427737A1 (fr) 2010-12-20 2019-01-16 NeuroVive Pharmaceutical AB Dérivés de sanglifehrine et procédés pour leur production
JO3063B1 (ar) 2011-03-29 2017-03-15 Neurovive Pharmaceutical Ab مركب مبتكر وطرق لانتاجه
WO2012145427A1 (fr) * 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Méthodes de traitement du cancer à l'aide de cyclosporine et de dérivés de cyclosporine
GB201118334D0 (en) 2011-10-24 2011-12-07 Biotica Tech Ltd Novel dosage form
AR091279A1 (es) * 2012-06-08 2015-01-21 Gilead Sciences Inc Inhibidores macrociclicos de virus flaviviridae
JP6209601B2 (ja) * 2012-06-08 2017-10-04 ギリアード サイエンシーズ， インコーポレイテッド フラビウイルス科ウイルスの大環状阻害剤
SI2859009T1 (sl) 2012-06-08 2017-12-29 Gilead Sciences, Inc. Makrociklični inhibitorji flaviviridae virusov

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US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
DE69132332T2 (de) 1990-04-06 2000-11-30 Genelabs Tech Inc Hepatitis c-virus-epitope
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
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AR006514A1 (es) 1995-07-04 1999-09-08 Sandoz Ag Un macrolido, sus usos, un proceso para producirlo, un aislado biologicamente puro capaz de producirlo, y una composicion farmaceutica quelo comprende
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
US5990276A (en) 1996-05-10 1999-11-23 Schering Corporation Synthetic inhibitors of hepatitis C virus NS3 protease
NZ335276A (en) 1996-10-18 2000-09-29 Vertex Pharma Inhibitors of serine proteases, particularly hepatitis C virus (HCV) NS3 (Non Structural Protein 3) protease
GB9623908D0 (en) 1996-11-18 1997-01-08 Hoffmann La Roche Amino acid derivatives
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ES2234144T3 (es) 1997-08-11 2005-06-16 Boehringer Ingelheim (Canada) Ltd. Analogos de peptidos inhibidores de la hepatitis c.
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EP1343807B1 (fr) 2000-12-12 2009-04-29 Schering Corporation Peptides diaryliques utilises comme inhibiteurs de ns3-serine protease du virus de l'hepatite c
AU2002230764A1 (en) 2000-12-13 2002-06-24 Bristol-Myers Squibb Pharma Company Imidazolidinones and their related derivatives as hepatitis c virus ns3 protease inhibitors
WO2002048116A2 (fr) 2000-12-13 2002-06-20 Bristol-Myers Squibb Pharma Company Inhibiteurs de la protease ns3 du virus de l'hepatite c
AU2003248748A1 (en) 2002-06-28 2004-01-19 Idenix (Cayman) Limited 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
JP4892486B2 (ja) * 2004-10-01 2012-03-07 デビオファーム ソシエテ アノニム Ｃ型肝炎感染の治療のための［ｄ−ｍｅａｌａ］３−［ｅｔｖａｌ］４−シクロスポリンの使用、及び当該［ｄ−ｍｅａｌａ］３−［ｅｔｖａｌ］４−シクロスポリンを含む医薬組成物
US7897565B2 (en) * 2004-12-23 2011-03-01 Novartis Ag Compositions for HCV treatment

Also Published As

Publication number Publication date
AU2006259348A1 (en) 2006-12-28
KR20080033274A (ko) 2008-04-16
RU2427372C2 (ru) 2011-08-27
AR054778A1 (es) 2007-07-18
EP1893211A1 (fr) 2008-03-05
GT200600262A (es) 2007-03-28
US20090221598A1 (en) 2009-09-03
ECSP078029A (es) 2008-01-23
CA2611151A1 (fr) 2006-12-28
EP1893211B1 (fr) 2011-09-14
NO20080351L (no) 2008-03-14
ATE524183T1 (de) 2011-09-15
PE20070118A1 (es) 2007-02-23
BRPI0613142A2 (pt) 2010-12-21
RU2008100587A (ru) 2009-07-27
ZA200710551B (en) 2008-11-26
WO2006138507A1 (fr) 2006-12-28
TNSN07477A1 (en) 2009-03-17
AU2006259348B2 (en) 2010-07-22
TW200740438A (en) 2007-11-01
JP2008546708A (ja) 2008-12-25
MX2007016068A (es) 2008-03-10
CN101242842A (zh) 2008-08-13

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