ECSP078029A - Uso de sanglifehrina en hcv - Google Patents

Uso de sanglifehrina en hcv

Info

Publication number
ECSP078029A
ECSP078029A EC2007008029A ECSP078029A ECSP078029A EC SP078029 A ECSP078029 A EC SP078029A EC 2007008029 A EC2007008029 A EC 2007008029A EC SP078029 A ECSP078029 A EC SP078029A EC SP078029 A ECSP078029 A EC SP078029A
Authority
EC
Ecuador
Prior art keywords
sanglifehrina
hcv
sanglifehrine
hepatitis
prevention
Prior art date
Application number
EC2007008029A
Other languages
English (en)
Inventor
Kai Lin
Beat Weidmann
Kaspar Zimmermann
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37075234&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP078029(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP078029A publication Critical patent/ECSP078029A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención da a conocer el uso de un compuesto de macrólido, tal como una sanglifehrina, para el tratamiento y la prevención de hepatitis C y enfermedades relacionadas, tales como fibrosis hepática, cirrosis hepática, y carcinoma hepatocelular.
EC2007008029A 2005-06-17 2007-12-17 Uso de sanglifehrina en hcv ECSP078029A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69149705P 2005-06-17 2005-06-17

Publications (1)

Publication Number Publication Date
ECSP078029A true ECSP078029A (es) 2008-01-23

Family

ID=37075234

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007008029A ECSP078029A (es) 2005-06-17 2007-12-17 Uso de sanglifehrina en hcv

Country Status (21)

Country Link
US (1) US20090221598A1 (es)
EP (1) EP1893211B1 (es)
JP (1) JP2008546708A (es)
KR (1) KR20080033274A (es)
CN (1) CN101242842A (es)
AR (1) AR054778A1 (es)
AT (1) ATE524183T1 (es)
AU (1) AU2006259348B2 (es)
BR (1) BRPI0613142A2 (es)
CA (1) CA2611151A1 (es)
EC (1) ECSP078029A (es)
GT (1) GT200600262A (es)
MA (1) MA29600B1 (es)
MX (1) MX2007016068A (es)
NO (1) NO20080351L (es)
PE (1) PE20070118A1 (es)
RU (1) RU2427372C2 (es)
TN (1) TNSN07477A1 (es)
TW (1) TW200740438A (es)
WO (1) WO2006138507A1 (es)
ZA (1) ZA200710551B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102224242B (zh) * 2008-09-24 2014-09-24 中国科学院上海有机化学研究所 新基因簇
WO2011011632A1 (en) * 2009-07-22 2011-01-27 Tufts University Methods and compositions for modulating membrane potential to influence cell behavior
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
EP2533784B1 (en) 2010-02-09 2015-04-22 Neurovive Pharmaceutical AB Sanglifehrin based compounds
WO2011098805A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
WO2011098808A1 (en) 2010-02-09 2011-08-18 Biotica Technology Limited Sanglifehrin based compounds
GB201008123D0 (en) 2010-05-17 2010-06-30 Biotica Tech Ltd Novel compounds
UY33775A (es) * 2010-12-10 2012-07-31 Gilead Sciences Inc Inhibidores macrocíclicos de virus flaviviridae, composiciones farmacéuticas que los comprenden y sus usos
EP3427737A1 (en) 2010-12-20 2019-01-16 NeuroVive Pharmaceutical AB Sanglifehrin derivatives and methods for their production
JO3063B1 (ar) 2011-03-29 2017-03-15 Neurovive Pharmaceutical Ab مركب مبتكر وطرق لانتاجه
WO2012145427A1 (en) * 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Methods to treat cancer using cyclosporine and cyclosporine derivatives
GB201118334D0 (en) 2011-10-24 2011-12-07 Biotica Tech Ltd Novel dosage form
AR091279A1 (es) * 2012-06-08 2015-01-21 Gilead Sciences Inc Inhibidores macrociclicos de virus flaviviridae
JP6209601B2 (ja) * 2012-06-08 2017-10-04 ギリアード サイエンシーズ， インコーポレイテッド フラビウイルス科ウイルスの大環状阻害剤
SI2859009T1 (sl) 2012-06-08 2017-12-29 Gilead Sciences, Inc. Makrociklični inhibitorji flaviviridae virusov

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US4917888A (en) 1985-06-26 1990-04-17 Cetus Corporation Solubilization of immunotoxins for pharmaceutical compositions using polymer conjugation
US4766106A (en) 1985-06-26 1988-08-23 Cetus Corporation Solubilization of proteins for pharmaceutical compositions using polymer conjugation
JP2514950B2 (ja) 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
GB2222770B (en) 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
DE69132332T2 (de) 1990-04-06 2000-11-30 Genelabs Tech Inc Hepatitis c-virus-epitope
US5595732A (en) 1991-03-25 1997-01-21 Hoffmann-La Roche Inc. Polyethylene-protein conjugates
US5382657A (en) 1992-08-26 1995-01-17 Hoffmann-La Roche Inc. Peg-interferon conjugates
GB9318612D0 (en) 1993-09-08 1993-10-27 Sandoz Ltd An assay
NZ276943A (en) 1993-11-10 1998-02-26 Schering Corp Substituted For Alpha-interferon conjugated to a non-antigenic polymer (preferably a polyalkylene oxide) and its preparation
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US6124453A (en) 1995-07-04 2000-09-26 Novartis Ag Macrolides
AR006514A1 (es) 1995-07-04 1999-09-08 Sandoz Ag Un macrolido, sus usos, un proceso para producirlo, un aislado biologicamente puro capaz de producirlo, y una composicion farmaceutica quelo comprende
US5908621A (en) 1995-11-02 1999-06-01 Schering Corporation Polyethylene glycol modified interferon therapy
US5990276A (en) 1996-05-10 1999-11-23 Schering Corporation Synthetic inhibitors of hepatitis C virus NS3 protease
NZ335276A (en) 1996-10-18 2000-09-29 Vertex Pharma Inhibitors of serine proteases, particularly hepatitis C virus (HCV) NS3 (Non Structural Protein 3) protease
GB9623908D0 (en) 1996-11-18 1997-01-08 Hoffmann La Roche Amino acid derivatives
US6004933A (en) 1997-04-25 1999-12-21 Cortech Inc. Cysteine protease inhibitors
ES2234144T3 (es) 1997-08-11 2005-06-16 Boehringer Ingelheim (Canada) Ltd. Analogos de peptidos inhibidores de la hepatitis c.
GB9806815D0 (en) 1998-03-30 1998-05-27 Hoffmann La Roche Amino acid derivatives
GB9811854D0 (en) * 1998-06-02 1998-07-29 Ciba Geigy Ag Organic compounds
US6444652B1 (en) 1998-08-10 2002-09-03 Novirio Pharmaceuticals Limited β-L-2'-deoxy-nucleosides for the treatment of hepatitis B
US6323180B1 (en) 1998-08-10 2001-11-27 Boehringer Ingelheim (Canada) Ltd Hepatitis C inhibitor tri-peptides
MY164523A (en) 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
YU92202A (sh) 2000-05-26 2006-01-16 Idenix (Cayman) Limited Metode i smeše za lečenje flavi virusa i pesti virusa
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AR029851A1 (es) 2000-07-21 2003-07-16 Dendreon Corp Nuevos peptidos como inhibidores de ns3-serina proteasa del virus de hepatitis c
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AU2003248748A1 (en) 2002-06-28 2004-01-19 Idenix (Cayman) Limited 2'-c-methyl-3'-o-l-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
GB0320638D0 (en) 2003-09-03 2003-10-01 Novartis Ag Organic compounds
JP4892486B2 (ja) * 2004-10-01 2012-03-07 デビオファーム ソシエテ アノニム Ｃ型肝炎感染の治療のための［ｄ−ｍｅａｌａ］３−［ｅｔｖａｌ］４−シクロスポリンの使用、及び当該［ｄ−ｍｅａｌａ］３−［ｅｔｖａｌ］４−シクロスポリンを含む医薬組成物
US7897565B2 (en) * 2004-12-23 2011-03-01 Novartis Ag Compositions for HCV treatment

Also Published As

Publication number Publication date
MA29600B1 (fr) 2008-07-01
AU2006259348A1 (en) 2006-12-28
KR20080033274A (ko) 2008-04-16
RU2427372C2 (ru) 2011-08-27
AR054778A1 (es) 2007-07-18
EP1893211A1 (en) 2008-03-05
GT200600262A (es) 2007-03-28
US20090221598A1 (en) 2009-09-03
CA2611151A1 (en) 2006-12-28
EP1893211B1 (en) 2011-09-14
NO20080351L (no) 2008-03-14
ATE524183T1 (de) 2011-09-15
PE20070118A1 (es) 2007-02-23
BRPI0613142A2 (pt) 2010-12-21
RU2008100587A (ru) 2009-07-27
ZA200710551B (en) 2008-11-26
WO2006138507A1 (en) 2006-12-28
TNSN07477A1 (en) 2009-03-17
AU2006259348B2 (en) 2010-07-22
TW200740438A (en) 2007-11-01
JP2008546708A (ja) 2008-12-25
MX2007016068A (es) 2008-03-10
CN101242842A (zh) 2008-08-13

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