UA104600C2 - Комбинированная терапия с применением пептида эпоксикетона - Google Patents

Комбинированная терапия с применением пептида эпоксикетона

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Publication number
UA104600C2
UA104600C2 UAA201106354A UAA201106354A UA104600C2 UA 104600 C2 UA104600 C2 UA 104600C2 UA A201106354 A UAA201106354 A UA A201106354A UA A201106354 A UAA201106354 A UA A201106354A UA 104600 C2 UA104600 C2 UA 104600C2
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UA
Ukraine
Prior art keywords
combination therapy
administered
peptide
peptide epoxyketones
epoxyketones
Prior art date
Application number
UAA201106354A
Other languages
English (en)
Ukrainian (uk)
Inventor
Крістофер Дж. Кірк
Сьюзан Д. Демо
Марк К. Беннетт
Original Assignee
Онікс Терап'Ютікс, Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42119657&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA104600(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Онікс Терап'Ютікс, Інк. filed Critical Онікс Терап'Ютікс, Інк.
Publication of UA104600C2 publication Critical patent/UA104600C2/ru

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Abstract

Изобретение касается комбинированной терапии пептида эпоксикетона и дексаметазона при лечении множественной миеломы, где пептид эпоксикетона и дексаметазон вводятся на протяжении от приблизительно 5 минут до приблизительно 48 часов друг после друга.
UAA201106354A 2008-10-21 2009-10-21 Комбинированная терапия с применением пептида эпоксикетона UA104600C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19694508P 2008-10-21 2008-10-21
PCT/US2009/061498 WO2010048298A1 (en) 2008-10-21 2009-10-21 Combination therapy with peptide epoxyketones

Publications (1)

Publication Number Publication Date
UA104600C2 true UA104600C2 (ru) 2014-02-25

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ID=42119657

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201106354A UA104600C2 (ru) 2008-10-21 2009-10-21 Комбинированная терапия с применением пептида эпоксикетона

Country Status (27)

Country Link
US (5) US20110236428A1 (ru)
EP (3) EP3090737A1 (ru)
JP (4) JP5675629B2 (ru)
KR (1) KR20110073584A (ru)
CN (1) CN102256616A (ru)
AP (1) AP2011005690A0 (ru)
AU (4) AU2009308516B2 (ru)
BR (1) BRPI0919668A2 (ru)
CA (1) CA2741312C (ru)
CL (1) CL2011000916A1 (ru)
CO (1) CO6361942A2 (ru)
CR (1) CR20110221A (ru)
DO (1) DOP2011000108A (ru)
EA (2) EA024364B1 (ru)
EC (1) ECSP11011027A (ru)
ES (1) ES2617560T3 (ru)
HK (1) HK1202436A1 (ru)
IL (1) IL212506A0 (ru)
MA (1) MA32806B1 (ru)
ME (1) ME01133B (ru)
MX (2) MX2011004225A (ru)
NI (1) NI201100077A (ru)
PE (1) PE20120059A1 (ru)
TN (1) TN2011000200A1 (ru)
UA (1) UA104600C2 (ru)
WO (1) WO2010048298A1 (ru)
ZA (1) ZA201103493B (ru)

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KR101274417B1 (ko) 2005-11-09 2013-06-17 프로테올릭스, 인코퍼레이티드 효소 저해를 위한 화합물
CA2657213C (en) 2006-06-19 2017-01-03 Proteolix, Inc. Peptide epoxyketones for proteasome inhibition
MY173938A (en) 2007-10-04 2020-02-27 Onyx Therapeutics Inc Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
PE20120059A1 (es) 2008-10-21 2012-02-27 Onyx Therapeutics Inc Combinaciones farmaceuticas con epoxicetonas peptidicas
TWI504598B (zh) 2009-03-20 2015-10-21 Onyx Therapeutics Inc 結晶性三肽環氧酮蛋白酶抑制劑
WO2011060179A1 (en) * 2009-11-13 2011-05-19 Onyx Therapeutics, Inc Use of peptide epoxyketones for metastasis suppression
MA34133B1 (fr) 2010-03-01 2013-04-03 Onyx Therapeutics Inc Composes pour inhibiteurs de l'immunoproteasome
AU2011245630B2 (en) 2010-04-07 2014-07-03 Onyx Therapeutics, Inc. Crystalline peptide epoxyketone immunoproteasome inhibitor
CN104411334A (zh) 2012-05-08 2015-03-11 欧尼斯治疗公司 用于配制肽蛋白酶体抑制剂的环糊精络合法
WO2014011695A2 (en) 2012-07-09 2014-01-16 Onyx Therapeutics, Inc. Prodrugs of peptide epoxy ketone protease inhibitors
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