MA31456B1 - Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenant - Google Patents
Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenantInfo
- Publication number
- MA31456B1 MA31456B1 MA32435A MA32435A MA31456B1 MA 31456 B1 MA31456 B1 MA 31456B1 MA 32435 A MA32435 A MA 32435A MA 32435 A MA32435 A MA 32435A MA 31456 B1 MA31456 B1 MA 31456B1
- Authority
- MA
- Morocco
- Prior art keywords
- iron
- drugs
- complex
- derivatives
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Obesity (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne un complexe de fer et de dérivés d'hydrates de carbone, pouvant être obtenu à partir d'une solution saline de fer(iii) aqueuse et d'une solution aqueuse du produit de l'oxydation, et par dérivatisation consécutive d'une ou plusieurs maltodextrines avec une solution d'hypochlorite aqueuse à un ph alcalin. En cas d'utilisation d'une maltodextrine, l'équivalent dextrose de celle-ci se situe entre 5 et 20, et en cas d'utilisation d'un mélange de plusieurs maltodextrines, l'équivalent dextrose du mélange se situe entre 5 et 20 et l'équivalent dextrose de chaque maltodextrine contenue dans le mélange se situe entre 2 et 40, la dérivatisation consécutive étant réalisée avec un réactif adéquat. L'invention concerne également des procédés de fabrication de ces complexes et des médicaments de prophylaxie et de traitement d'états de carences en fer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07109081A EP1997833A1 (fr) | 2007-05-29 | 2007-05-29 | Complexes fer-dérivé d'hydrate de carbone hydrosolubles, leur fabrication et médicaments contenants ces complexes |
PCT/EP2008/056276 WO2008145586A1 (fr) | 2007-05-29 | 2008-05-21 | Complexes de fer et de dérivés d'hydrates de carbone solubles dans l'eau, leur fabrication et médicaments les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31456B1 true MA31456B1 (fr) | 2010-06-01 |
Family
ID=38287550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32435A MA31456B1 (fr) | 2007-05-29 | 2009-12-21 | Complexes de fer et de derives d'hydrates de carbone solubles dans l'eau, leur fabrication et medicaments les contenant |
Country Status (27)
Country | Link |
---|---|
US (1) | US8263577B2 (fr) |
EP (2) | EP1997833A1 (fr) |
JP (1) | JP5259700B2 (fr) |
KR (1) | KR101168085B1 (fr) |
CN (1) | CN101679530B (fr) |
AR (1) | AR065997A1 (fr) |
AU (1) | AU2008257683B2 (fr) |
BR (1) | BRPI0811985B8 (fr) |
CA (1) | CA2682587C (fr) |
CL (1) | CL2008001549A1 (fr) |
CO (1) | CO6241161A2 (fr) |
ES (1) | ES2547304T3 (fr) |
GT (1) | GT200900308A (fr) |
HK (1) | HK1140219A1 (fr) |
IL (1) | IL201294A (fr) |
MA (1) | MA31456B1 (fr) |
MX (1) | MX2009012889A (fr) |
MY (1) | MY158004A (fr) |
NZ (1) | NZ581487A (fr) |
PE (1) | PE20090317A1 (fr) |
PL (1) | PL2148890T3 (fr) |
PT (1) | PT2148890E (fr) |
RU (1) | RU2441881C2 (fr) |
TN (1) | TN2009000443A1 (fr) |
TW (1) | TWI372621B (fr) |
WO (1) | WO2008145586A1 (fr) |
ZA (1) | ZA200907672B (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10249552A1 (de) * | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
EP2626074A1 (fr) | 2006-01-06 | 2013-08-14 | Luitpold Pharmaceuticals, Inc. | Procédés et compositions pour l'administration de fer |
EP3156075B1 (fr) | 2009-03-25 | 2020-10-14 | Pharmacosmos Holding A/S | Oligoside et son procédé de préparation |
WO2011055374A2 (fr) * | 2009-11-04 | 2011-05-12 | Symed Labs Limited | Procédé de préparation d'un complexe de carboxymaltose ferrique |
ES2660202T3 (es) | 2010-03-23 | 2018-03-21 | Vifor (International) Ag | Compuestos del complejo Fe (iii) para el tratamiento y la profilaxis de los síntomas de deficiencia de hierro y las anemias ferropénicas |
CN101891832B (zh) * | 2010-07-22 | 2012-01-04 | 山东农业大学 | 一种无碱均相生产氧化淀粉方法 |
WO2012104204A1 (fr) | 2011-01-31 | 2012-08-09 | Vifor (International) Ag | Composés à base d'un complexe de fer-hydrate de carbone pour la thérapie intraveineuse du paludisme |
WO2013056085A1 (fr) * | 2011-10-13 | 2013-04-18 | Vidasym, Inc. | Composition de fibre de fer, sa préparation et ses utilisations |
JP6417339B2 (ja) | 2013-03-08 | 2018-11-07 | ヴィダシム・インコーポレーテッド | 金属イオン−機能性繊維成分錯体組成物、その調製および使用 |
US9370202B2 (en) * | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
US20180105609A1 (en) * | 2015-03-23 | 2018-04-19 | Suven Life Sciences Limited | Preparation of water soluble trivalent iron carbohydrate complexes |
CN105125577B (zh) * | 2015-07-29 | 2018-05-18 | 南京生命能科技开发有限公司 | 一种稳定的糖-铁复合物及其制备方法 |
CN105520955B (zh) * | 2015-12-21 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种羧基麦芽糖铁药用组合物及其制备方法 |
WO2019193608A1 (fr) * | 2018-04-05 | 2019-10-10 | Msn Laboratories Private Limited, R&D Center | Procédé amélioré pour la préparation de carboxymaltose ferrique |
CN115368478B (zh) * | 2021-05-21 | 2023-07-04 | 武汉科福新药有限责任公司 | 一种羧基麦芽糖铁的制备方法 |
CN115368477B (zh) * | 2021-05-21 | 2023-05-02 | 武汉科福新药有限责任公司 | 高得率、高含铁量的羧基麦芽糖铁的制备方法 |
CN115322265A (zh) * | 2022-08-29 | 2022-11-11 | 滨州学院 | 一种羧基麦芽糖控制性氧化与纯化工艺 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK172860B1 (da) * | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
DE10249552A1 (de) * | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
ITMO20050056A1 (it) | 2005-03-15 | 2006-09-16 | Biofer Spa | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. |
EP1757299A1 (fr) * | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Complexes de fer III pour traiter les manques de fer en patients avec la maladie intestinale inflammatoire |
-
2007
- 2007-05-29 EP EP07109081A patent/EP1997833A1/fr not_active Withdrawn
-
2008
- 2008-04-09 AR ARP080101467A patent/AR065997A1/es not_active Application Discontinuation
- 2008-04-30 TW TW097115868A patent/TWI372621B/zh not_active IP Right Cessation
- 2008-05-21 EP EP08759877.7A patent/EP2148890B1/fr active Active
- 2008-05-21 RU RU2009149175/05A patent/RU2441881C2/ru active
- 2008-05-21 BR BRPI0811985A patent/BRPI0811985B8/pt not_active IP Right Cessation
- 2008-05-21 NZ NZ581487A patent/NZ581487A/en not_active IP Right Cessation
- 2008-05-21 CA CA2682587A patent/CA2682587C/fr not_active Expired - Fee Related
- 2008-05-21 PL PL08759877T patent/PL2148890T3/pl unknown
- 2008-05-21 MX MX2009012889A patent/MX2009012889A/es active IP Right Grant
- 2008-05-21 PT PT87598777T patent/PT2148890E/pt unknown
- 2008-05-21 AU AU2008257683A patent/AU2008257683B2/en not_active Ceased
- 2008-05-21 KR KR1020097023006A patent/KR101168085B1/ko active IP Right Grant
- 2008-05-21 ES ES08759877.7T patent/ES2547304T3/es active Active
- 2008-05-21 CN CN2008800178628A patent/CN101679530B/zh not_active Expired - Fee Related
- 2008-05-21 JP JP2010509794A patent/JP5259700B2/ja not_active Expired - Fee Related
- 2008-05-21 WO PCT/EP2008/056276 patent/WO2008145586A1/fr active Application Filing
- 2008-05-21 US US12/599,343 patent/US8263577B2/en active Active
- 2008-05-21 MY MYPI20094711A patent/MY158004A/en unknown
- 2008-05-28 PE PE2008000908A patent/PE20090317A1/es not_active Application Discontinuation
- 2008-05-28 CL CL2008001549A patent/CL2008001549A1/es unknown
-
2009
- 2009-10-01 IL IL201294A patent/IL201294A/en not_active IP Right Cessation
- 2009-10-22 CO CO09118656A patent/CO6241161A2/es active IP Right Grant
- 2009-10-23 TN TNP2009000443A patent/TN2009000443A1/fr unknown
- 2009-11-02 ZA ZA200907672A patent/ZA200907672B/xx unknown
- 2009-11-27 GT GT200900308A patent/GT200900308A/es unknown
- 2009-12-21 MA MA32435A patent/MA31456B1/fr unknown
-
2010
- 2010-06-25 HK HK10106277.9A patent/HK1140219A1/xx not_active IP Right Cessation
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