MA19948A1 - Procede de preparation de derives de la piperidine-dione protecteur du myocarde presentant une activite antiarithmique - Google Patents
Procede de preparation de derives de la piperidine-dione protecteur du myocarde presentant une activite antiarithmiqueInfo
- Publication number
- MA19948A1 MA19948A1 MA20168A MA20168A MA19948A1 MA 19948 A1 MA19948 A1 MA 19948A1 MA 20168 A MA20168 A MA 20168A MA 20168 A MA20168 A MA 20168A MA 19948 A1 MA19948 A1 MA 19948A1
- Authority
- MA
- Morocco
- Prior art keywords
- antiarithmic
- piperidine
- activity
- preparation
- dione derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8218706A FR2535721A1 (fr) | 1982-11-08 | 1982-11-08 | Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA19948A1 true MA19948A1 (fr) | 1984-07-01 |
Family
ID=9279000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA20168A MA19948A1 (fr) | 1982-11-08 | 1983-11-07 | Procede de preparation de derives de la piperidine-dione protecteur du myocarde presentant une activite antiarithmique |
Country Status (29)
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4668689A (en) * | 1984-07-19 | 1987-05-26 | National Research Development Corporation | Glutarimide derivatives for treating oestrogen-dependent tumors |
| US5238947A (en) * | 1990-04-12 | 1993-08-24 | University Of Georgia Research Foundation, Inc. | Synthetic piperidinediones with cytostatic activity |
| US5463063A (en) * | 1993-07-02 | 1995-10-31 | Celgene Corporation | Ring closure of N-phthaloylglutamines |
| DE19703763C1 (de) * | 1997-02-01 | 1998-10-01 | Gruenenthal Gmbh | Thalidomidanaloge Verbindungen aus der Klasse der Piperidin-2,6-Dione |
| CN103534258B (zh) | 2011-05-17 | 2016-09-14 | 普林斯匹亚生物制药公司 | 酪氨酸激酶抑制剂 |
| WO2012158795A1 (en) | 2011-05-17 | 2012-11-22 | Principia Biopharma Inc. | Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors |
| EP2710007B1 (en) | 2011-05-17 | 2019-12-11 | The Regents of The University of California | Kinase inhibitors |
| JP6203848B2 (ja) | 2012-09-10 | 2017-09-27 | プリンシピア バイオファーマ インコーポレイテッド | キナーゼ阻害剤としてのピラゾロピリミジン化合物 |
| US8957080B2 (en) | 2013-04-09 | 2015-02-17 | Principia Biopharma Inc. | Tyrosine kinase inhibitors |
| ES2841248T3 (es) | 2014-02-21 | 2021-07-07 | Principia Biopharma Inc | Sales y forma sólida de un inhibidor de BTK |
| CA2970723C (en) | 2014-12-18 | 2023-09-05 | Principia Biopharma Inc. | Treatment of pemphigus |
| EP3313839A1 (en) | 2015-06-24 | 2018-05-02 | Principia Biopharma Inc. | Tyrosine kinase inhibitors |
| AU2017290354C1 (en) | 2016-06-29 | 2023-07-06 | Principia Biopharma Inc. | Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile |
| JP2022550919A (ja) | 2019-10-14 | 2022-12-05 | プリンシピア バイオファーマ インコーポレイテッド | （ｒ）－２－［３－［４－アミノ－３－（２－フルオロ－４－フェノキシ－フェニル）ピラゾロ［３，４－ｄ］ピリミジン－１－イル］ピペリジン－１－カルボニル］－４－メチル－４－［４－（オキセタン－３－イル）ピペラジン－１－イル］ペンタ－２－エンニトリルを投与することにより免疫性血小板減少症を治療する方法 |
| EP4093741A1 (en) | 2020-01-22 | 2022-11-30 | Principia Biopharma Inc. | Crystalline forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2664424A (en) * | 1953-12-29 | Dioxo-piperidines | ||
| GB1455687A (en) * | 1972-12-28 | 1976-11-17 | Aspro Nicholas Ltd | Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines |
| FR2467200A1 (fr) * | 1979-10-11 | 1981-04-17 | Clin Midy | Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire |
-
1982
- 1982-11-08 FR FR8218706A patent/FR2535721A1/fr active Granted
-
1983
- 1983-10-28 ZA ZA838065A patent/ZA838065B/xx unknown
- 1983-10-31 IL IL70099A patent/IL70099A/xx unknown
- 1983-11-02 AU AU20898/83A patent/AU565519B2/en not_active Ceased
- 1983-11-04 EP EP83402142A patent/EP0110755B1/fr not_active Expired
- 1983-11-04 AT AT83402142T patent/ATE22561T1/de not_active IP Right Cessation
- 1983-11-04 DE DE8383402142T patent/DE3366623D1/de not_active Expired
- 1983-11-04 PT PT77607A patent/PT77607B/pt not_active IP Right Cessation
- 1983-11-04 IE IE2581/83A patent/IE56209B1/xx unknown
- 1983-11-04 GR GR72874A patent/GR78747B/el unknown
- 1983-11-05 SU SU833661804A patent/SU1333237A3/ru active
- 1983-11-07 DD DD83270120A patent/DD229407A5/de not_active IP Right Cessation
- 1983-11-07 DD DD83270121A patent/DD229402A5/de not_active IP Right Cessation
- 1983-11-07 NZ NZ206177A patent/NZ206177A/en unknown
- 1983-11-07 DD DD83256411A patent/DD219770A5/de not_active IP Right Cessation
- 1983-11-07 MA MA20168A patent/MA19948A1/fr unknown
- 1983-11-07 NO NO834057A patent/NO159852C/no unknown
- 1983-11-08 KR KR1019830005288A patent/KR900006721B1/ko not_active Expired
- 1983-11-08 YU YU02211/83A patent/YU221183A/xx unknown
- 1983-11-08 JP JP58209772A patent/JPS59161377A/ja active Pending
- 1983-11-08 PH PH29800A patent/PH20421A/en unknown
- 1983-11-08 OA OA58153A patent/OA07582A/xx unknown
- 1983-11-08 ES ES527091A patent/ES8406070A1/es not_active Expired
- 1983-11-08 CS CS838220A patent/CS244681B2/cs unknown
- 1983-11-08 DK DK511383A patent/DK511383A/da not_active Application Discontinuation
- 1983-11-08 CA CA000440675A patent/CA1221967A/en not_active Expired
- 1983-11-08 PL PL1983244462A patent/PL139946B1/pl unknown
- 1983-11-08 PL PL1983249750A patent/PL140021B1/pl unknown
- 1983-11-08 FI FI834087A patent/FI79536C/fi not_active IP Right Cessation
- 1983-11-08 PL PL1983249749A patent/PL140992B1/pl unknown
- 1983-11-08 HU HU833827A patent/HU191494B/hu not_active IP Right Cessation
-
1984
- 1984-09-06 SU SU843786907A patent/SU1316558A3/ru active
- 1984-09-06 SU SU843786916A patent/SU1333238A3/ru active
-
1985
- 1985-11-26 YU YU01841/85A patent/YU184185A/xx unknown
- 1985-11-26 YU YU01842/85A patent/YU184285A/xx unknown
-
1986
- 1986-03-10 US US06/838,255 patent/US4721710A/en not_active Expired - Fee Related
-
1989
- 1989-01-11 SG SG19/89A patent/SG1989G/en unknown
Also Published As
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