ES527091A0 - Procedimiento para la fabricacion de la piperidindiona protectora del miocardio, con actividad antiarritmica - Google Patents

Procedimiento para la fabricacion de la piperidindiona protectora del miocardio, con actividad antiarritmica

Info

Publication number
ES527091A0
ES527091A0 ES527091A ES527091A ES527091A0 ES 527091 A0 ES527091 A0 ES 527091A0 ES 527091 A ES527091 A ES 527091A ES 527091 A ES527091 A ES 527091A ES 527091 A0 ES527091 A0 ES 527091A0
Authority
ES
Spain
Prior art keywords
piperidindiona
miocardio
protective
procedure
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES527091A
Other languages
English (en)
Other versions
ES8406070A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of ES527091A0 publication Critical patent/ES527091A0/es
Publication of ES8406070A1 publication Critical patent/ES8406070A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES527091A 1982-11-08 1983-11-08 Procedimiento para la fabricacion de la piperidindiona protectora del miocardio, con actividad antiarritmica Expired ES8406070A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8218706A FR2535721A1 (fr) 1982-11-08 1982-11-08 Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives

Publications (2)

Publication Number Publication Date
ES527091A0 true ES527091A0 (es) 1984-07-01
ES8406070A1 ES8406070A1 (es) 1984-07-01

Family

ID=9279000

Family Applications (1)

Application Number Title Priority Date Filing Date
ES527091A Expired ES8406070A1 (es) 1982-11-08 1983-11-08 Procedimiento para la fabricacion de la piperidindiona protectora del miocardio, con actividad antiarritmica

Country Status (29)

Country Link
US (1) US4721710A (es)
EP (1) EP0110755B1 (es)
JP (1) JPS59161377A (es)
KR (1) KR900006721B1 (es)
AT (1) ATE22561T1 (es)
AU (1) AU565519B2 (es)
CA (1) CA1221967A (es)
CS (1) CS244681B2 (es)
DD (3) DD219770A5 (es)
DE (1) DE3366623D1 (es)
DK (1) DK511383A (es)
ES (1) ES8406070A1 (es)
FI (1) FI79536C (es)
FR (1) FR2535721A1 (es)
GR (1) GR78747B (es)
HU (1) HU191494B (es)
IE (1) IE56209B1 (es)
IL (1) IL70099A (es)
MA (1) MA19948A1 (es)
NO (1) NO159852C (es)
NZ (1) NZ206177A (es)
OA (1) OA07582A (es)
PH (1) PH20421A (es)
PL (3) PL140021B1 (es)
PT (1) PT77607B (es)
SG (1) SG1989G (es)
SU (3) SU1333237A3 (es)
YU (3) YU221183A (es)
ZA (1) ZA838065B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668689A (en) * 1984-07-19 1987-05-26 National Research Development Corporation Glutarimide derivatives for treating oestrogen-dependent tumors
US5238947A (en) * 1990-04-12 1993-08-24 University Of Georgia Research Foundation, Inc. Synthetic piperidinediones with cytostatic activity
JP5974084B2 (ja) 2011-05-17 2016-08-23 プリンシピア バイオファーマ インコーポレイテッド チロシンキナーゼ阻害剤
DK2710007T3 (da) 2011-05-17 2020-01-27 Principia Biopharma Inc Kinasehæmmere
US9376438B2 (en) 2011-05-17 2016-06-28 Principia Biopharma, Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
AU2013312296B2 (en) 2012-09-10 2017-06-22 Principia Biopharma Inc. Pyrazolopyrimidine compounds as kinase inhibitors
US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
EA033900B1 (ru) 2014-02-21 2019-12-06 Принсипиа Биофарма Инк. СОЛЕВЫЕ И АМОРФНЫЕ ФОРМЫ 2-[(3R)-3-[4-АМИНО-3-(2-ФТОР-4-ФЕНОКСИФЕНИЛ)ПИРАЗОЛО[3,4-d]ПИРИМИДИН-1-ИЛ]ПИПЕРИДИН-1-КАРБОНИЛ]-4-МЕТИЛ-4-[4-(ОКСЕТАН-3-ИЛ)ПИПЕРАЗИН-1-ИЛ]ПЕНТ-2-ЕННИТРИЛА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ ПУЗЫРЧАТКИ ОБЫКНОВЕННОЙ И ПУЗЫРЧАТКИ ЛИСТОВИДНОЙ С ИХ ПРИМЕНЕНИЕМ
EA036269B1 (ru) 2014-12-18 2020-10-21 Принсипиа Биофарма Инк. Лечение пузырчатки
US20180305350A1 (en) 2015-06-24 2018-10-25 Principia Biopharma Inc. Tyrosine kinase inhibitors
US20190231784A1 (en) 2016-06-29 2019-08-01 Principia Biopharma Inc. Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664424A (en) * 1953-12-29 Dioxo-piperidines
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
FR2467200A1 (fr) * 1979-10-11 1981-04-17 Clin Midy Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Also Published As

Publication number Publication date
PL249749A1 (en) 1985-03-12
KR900006721B1 (ko) 1990-09-20
EP0110755B1 (fr) 1986-10-01
PL249750A1 (en) 1985-03-12
YU221183A (en) 1986-06-30
IL70099A (en) 1987-10-20
DK511383A (da) 1984-05-09
IL70099A0 (en) 1984-01-31
CA1221967A (en) 1987-05-19
KR840006641A (ko) 1984-12-01
PL139946B1 (en) 1987-03-31
FI79536C (fi) 1990-01-10
GR78747B (es) 1984-10-02
FI834087A (fi) 1984-05-09
FI79536B (fi) 1989-09-29
NO834057L (no) 1984-05-09
ES8406070A1 (es) 1984-07-01
SU1333237A3 (ru) 1987-08-23
SG1989G (en) 1989-06-02
SU1333238A3 (ru) 1987-08-23
PT77607A (fr) 1983-12-01
PL140992B1 (en) 1987-06-30
IE56209B1 (en) 1991-05-22
NO159852B (no) 1988-11-07
ATE22561T1 (de) 1986-10-15
EP0110755A1 (fr) 1984-06-13
NZ206177A (en) 1985-11-08
SU1316558A3 (ru) 1987-06-07
JPS59161377A (ja) 1984-09-12
US4721710A (en) 1988-01-26
PH20421A (en) 1987-01-05
YU184185A (en) 1986-06-30
DD229407A5 (de) 1985-11-06
PT77607B (fr) 1986-03-18
AU2089883A (en) 1984-05-17
DD219770A5 (de) 1985-03-13
NO159852C (no) 1989-02-15
IE832581L (en) 1984-05-08
PL244462A1 (en) 1985-02-13
YU184285A (en) 1986-06-30
CS244681B2 (en) 1986-08-14
DK511383D0 (da) 1983-11-08
AU565519B2 (en) 1987-09-17
ZA838065B (en) 1984-06-27
FR2535721B1 (es) 1985-05-17
FR2535721A1 (fr) 1984-05-11
DE3366623D1 (en) 1986-11-06
DD229402A5 (de) 1985-11-06
FI834087A0 (fi) 1983-11-08
OA07582A (fr) 1985-03-31
MA19948A1 (fr) 1984-07-01
HU191494B (en) 1987-02-27
PL140021B1 (en) 1987-03-31

Similar Documents

Publication Publication Date Title
ES2040261T3 (es) Procedimiento para preparar acidos 6-fluor-4-oxo-1,4-dihidroquinolina-3-carboxilicos sustituidos y acidos 9-fluor-3-metil-7-oxo-2,3-dihidro-7h-pirido(1,2,3-de)(1,4)benzoxazina-6-carboxilico sustituidos.
ES527091A0 (es) Procedimiento para la fabricacion de la piperidindiona protectora del miocardio, con actividad antiarritmica
NO924598D0 (no) Fremstilling av substituerte piperidiner
DE3160360D1 (en) 5-subsituted 5,10-dihydro-11h-dibenzo(b,e)(1,4)diazepin-11-ones, process for preparing them and medicaments containing them
DE3378413D1 (en) Spiro-2-aza-alkane-3-carbonitriles, process for their preparation and their use
DK465182A (da) Fremgangsmaade til fremstilling af substituerede 6-chlor-4-phenyl quinazolin-derivater
DE68922344D1 (de) Herstellung von Enantiomeren des Dropropizins.
ES537558A0 (es) Un procedimiento para la preparacion del isomero r (dextrogiro)
HUT39445A (en) Herbicides containing as reagent derivatives of benzodisultam and process for production of the reagents
JPS57200370A (en) 1-acyl group substituted-4-hydroxyalkylhomopiperazine derivative
MX9300136A (es) Alfa-aril-alfa-hidroxi-beta-imidazolinil-propionamidas, procedimiento para su obtencion y medicamentos que las contienen.
BR8206677A (pt) Processo para a preparacao de alquilcicloalquil-imidazolil-meril-cetonas e aplicacao
ATE23340T1 (de) 3-alkylthio-2-0-carbamoylpropan-1,2-diol-1-0phosphocholine und verfahren zu ihrer herstellung.
BR8204444A (pt) Composicoes herbicidas a base de n-aminometil-halogeno-acetanilidas e processo para produzir estas ultimas
ES2056708T3 (es) Derivados de imino-2 polifluoralquil-6 heterociclilalquil-3 benzotiazolina, su preparacion y los medicamentos que les contienen.