DE68922344D1 - Herstellung von Enantiomeren des Dropropizins. - Google Patents

Herstellung von Enantiomeren des Dropropizins.

Info

Publication number
DE68922344D1
DE68922344D1 DE68922344T DE68922344T DE68922344D1 DE 68922344 D1 DE68922344 D1 DE 68922344D1 DE 68922344 T DE68922344 T DE 68922344T DE 68922344 T DE68922344 T DE 68922344T DE 68922344 D1 DE68922344 D1 DE 68922344D1
Authority
DE
Germany
Prior art keywords
enantiomers
dropropizin
production
dropropizine
phenylpiperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE68922344T
Other languages
English (en)
Other versions
DE68922344T2 (de
Inventor
Iersel Jacobus Theodorus M Van
Vincentius Henricus M Elferink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19852523&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68922344(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by DSM NV filed Critical DSM NV
Publication of DE68922344D1 publication Critical patent/DE68922344D1/de
Application granted granted Critical
Publication of DE68922344T2 publication Critical patent/DE68922344T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
DE68922344T 1988-06-25 1989-06-22 Herstellung von Enantiomeren des Dropropizins. Revoked DE68922344T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8801622A NL8801622A (nl) 1988-06-25 1988-06-25 Bereiding van enantiomeren van dropropizine.

Publications (2)

Publication Number Publication Date
DE68922344D1 true DE68922344D1 (de) 1995-06-01
DE68922344T2 DE68922344T2 (de) 1995-12-14

Family

ID=19852523

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922344T Revoked DE68922344T2 (de) 1988-06-25 1989-06-22 Herstellung von Enantiomeren des Dropropizins.

Country Status (5)

Country Link
EP (1) EP0349066B1 (de)
AT (1) ATE121737T1 (de)
DE (1) DE68922344T2 (de)
ES (1) ES2072288T3 (de)
NL (1) NL8801622A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1226570B (it) * 1988-08-01 1991-01-24 Bidachem Spa Procedimento di preparazione della levo- e destro-dropropizina
IT1231158B (it) * 1989-07-20 1991-11-19 Dompe Farmaceutici Spa Procedimento per la risoluzione ottica della dropropizina.
IT1254452B (it) * 1992-02-14 1995-09-25 Dompe Farmaceutici Spa N-ossidi ed n,n'-diossidi di 3-(piperazin-1-il)-propan-1,2-dioli
IT1254993B (it) * 1992-06-24 1995-10-11 Procedimento per la preparazione degli enantiomeri della dropropizina
IT1318650B1 (it) 2000-07-28 2003-08-27 Dompe Spa 1,3-diossolani ad attivita' antitosse.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE601394A (de) *
IT1203721B (it) * 1983-12-29 1989-02-23 Dompe Farmaceutici Spa Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono

Also Published As

Publication number Publication date
NL8801622A (nl) 1990-01-16
ATE121737T1 (de) 1995-05-15
EP0349066A1 (de) 1990-01-03
ES2072288T3 (es) 1995-07-16
EP0349066B1 (de) 1995-04-26
DE68922344T2 (de) 1995-12-14

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation