ATE22561T1 - Piperidindion-derivate mit herzmuskelschonender und antiarrhythmischer wirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. - Google Patents
Piperidindion-derivate mit herzmuskelschonender und antiarrhythmischer wirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel.Info
- Publication number
- ATE22561T1 ATE22561T1 AT83402142T AT83402142T ATE22561T1 AT E22561 T1 ATE22561 T1 AT E22561T1 AT 83402142 T AT83402142 T AT 83402142T AT 83402142 T AT83402142 T AT 83402142T AT E22561 T1 ATE22561 T1 AT E22561T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- piperidindone
- cariomusculant
- antiarhythmic
- effects
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8218706A FR2535721A1 (fr) | 1982-11-08 | 1982-11-08 | Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives |
EP83402142A EP0110755B1 (de) | 1982-11-08 | 1983-11-04 | Piperidindion-Derivate mit herzmuskelschonender und antiarrhythmischer Wirkung, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE22561T1 true ATE22561T1 (de) | 1986-10-15 |
Family
ID=9279000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT83402142T ATE22561T1 (de) | 1982-11-08 | 1983-11-04 | Piperidindion-derivate mit herzmuskelschonender und antiarrhythmischer wirkung, verfahren zu ihrer herstellung und sie enthaltende arzneimittel. |
Country Status (29)
Country | Link |
---|---|
US (1) | US4721710A (de) |
EP (1) | EP0110755B1 (de) |
JP (1) | JPS59161377A (de) |
KR (1) | KR900006721B1 (de) |
AT (1) | ATE22561T1 (de) |
AU (1) | AU565519B2 (de) |
CA (1) | CA1221967A (de) |
CS (1) | CS244681B2 (de) |
DD (3) | DD229407A5 (de) |
DE (1) | DE3366623D1 (de) |
DK (1) | DK511383A (de) |
ES (1) | ES527091A0 (de) |
FI (1) | FI79536C (de) |
FR (1) | FR2535721A1 (de) |
GR (1) | GR78747B (de) |
HU (1) | HU191494B (de) |
IE (1) | IE56209B1 (de) |
IL (1) | IL70099A (de) |
MA (1) | MA19948A1 (de) |
NO (1) | NO159852C (de) |
NZ (1) | NZ206177A (de) |
OA (1) | OA07582A (de) |
PH (1) | PH20421A (de) |
PL (3) | PL139946B1 (de) |
PT (1) | PT77607B (de) |
SG (1) | SG1989G (de) |
SU (3) | SU1333237A3 (de) |
YU (3) | YU221183A (de) |
ZA (1) | ZA838065B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4668689A (en) * | 1984-07-19 | 1987-05-26 | National Research Development Corporation | Glutarimide derivatives for treating oestrogen-dependent tumors |
US5238947A (en) * | 1990-04-12 | 1993-08-24 | University Of Georgia Research Foundation, Inc. | Synthetic piperidinediones with cytostatic activity |
AU2012255860C1 (en) | 2011-05-17 | 2015-12-10 | Principia Biopharma Inc. | Tyrosine kinase inhibitors |
WO2012158795A1 (en) | 2011-05-17 | 2012-11-22 | Principia Biopharma Inc. | Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors |
DK2710007T3 (da) | 2011-05-17 | 2020-01-27 | Principia Biopharma Inc | Kinasehæmmere |
EP2892900B1 (de) | 2012-09-10 | 2017-08-16 | Principia Biopharma Inc. | Pyrazolopyrimidin-verbindungen als kinase-inhibitoren |
US8957080B2 (en) | 2013-04-09 | 2015-02-17 | Principia Biopharma Inc. | Tyrosine kinase inhibitors |
SG11201606858RA (en) | 2014-02-21 | 2016-09-29 | Principia Biopharma Inc | Salts and solid form of a btk inhibitor |
ES2843323T3 (es) | 2014-12-18 | 2021-07-16 | Principia Biopharma Inc | Tratamiento de pénfigo |
TW201718572A (zh) | 2015-06-24 | 2017-06-01 | 普林斯匹亞生物製藥公司 | 酪胺酸激酶抑制劑 |
IL263815B (en) | 2016-06-29 | 2022-07-01 | Principia Biopharma Inc | Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[4,3-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4 -Methyl-4-[4-(Oxtan-3-yl)piperazin-1-yl)pent-2-ananitrile |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2664424A (en) * | 1953-12-29 | Dioxo-piperidines | ||
GB1455687A (en) * | 1972-12-28 | 1976-11-17 | Aspro Nicholas Ltd | Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines |
FR2467200A1 (fr) * | 1979-10-11 | 1981-04-17 | Clin Midy | Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire |
-
1982
- 1982-11-08 FR FR8218706A patent/FR2535721A1/fr active Granted
-
1983
- 1983-10-28 ZA ZA838065A patent/ZA838065B/xx unknown
- 1983-10-31 IL IL70099A patent/IL70099A/xx unknown
- 1983-11-02 AU AU20898/83A patent/AU565519B2/en not_active Ceased
- 1983-11-04 PT PT77607A patent/PT77607B/pt not_active IP Right Cessation
- 1983-11-04 IE IE2581/83A patent/IE56209B1/xx unknown
- 1983-11-04 EP EP83402142A patent/EP0110755B1/de not_active Expired
- 1983-11-04 AT AT83402142T patent/ATE22561T1/de not_active IP Right Cessation
- 1983-11-04 GR GR72874A patent/GR78747B/el unknown
- 1983-11-04 DE DE8383402142T patent/DE3366623D1/de not_active Expired
- 1983-11-05 SU SU833661804A patent/SU1333237A3/ru active
- 1983-11-07 NZ NZ206177A patent/NZ206177A/en unknown
- 1983-11-07 MA MA20168A patent/MA19948A1/fr unknown
- 1983-11-07 DD DD83270120A patent/DD229407A5/de not_active IP Right Cessation
- 1983-11-07 NO NO834057A patent/NO159852C/no unknown
- 1983-11-07 DD DD83270121A patent/DD229402A5/de not_active IP Right Cessation
- 1983-11-07 DD DD83256411A patent/DD219770A5/de not_active IP Right Cessation
- 1983-11-08 FI FI834087A patent/FI79536C/fi not_active IP Right Cessation
- 1983-11-08 PL PL1983244462A patent/PL139946B1/pl unknown
- 1983-11-08 ES ES527091A patent/ES527091A0/es active Granted
- 1983-11-08 YU YU02211/83A patent/YU221183A/xx unknown
- 1983-11-08 OA OA58153A patent/OA07582A/xx unknown
- 1983-11-08 HU HU833827A patent/HU191494B/hu not_active IP Right Cessation
- 1983-11-08 CS CS838220A patent/CS244681B2/cs unknown
- 1983-11-08 JP JP58209772A patent/JPS59161377A/ja active Pending
- 1983-11-08 PL PL1983249749A patent/PL140992B1/pl unknown
- 1983-11-08 DK DK511383A patent/DK511383A/da not_active Application Discontinuation
- 1983-11-08 CA CA000440675A patent/CA1221967A/en not_active Expired
- 1983-11-08 PL PL1983249750A patent/PL140021B1/pl unknown
- 1983-11-08 KR KR1019830005288A patent/KR900006721B1/ko active IP Right Grant
- 1983-11-08 PH PH29800A patent/PH20421A/en unknown
-
1984
- 1984-09-06 SU SU843786916A patent/SU1333238A3/ru active
- 1984-09-06 SU SU843786907A patent/SU1316558A3/ru active
-
1985
- 1985-11-26 YU YU01841/85A patent/YU184185A/xx unknown
- 1985-11-26 YU YU01842/85A patent/YU184285A/xx unknown
-
1986
- 1986-03-10 US US06/838,255 patent/US4721710A/en not_active Expired - Fee Related
-
1989
- 1989-01-11 SG SG19/89A patent/SG1989G/en unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |