PH20421A - Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them - Google Patents

Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them

Info

Publication number
PH20421A
PH20421A PH29800A PH29800A PH20421A PH 20421 A PH20421 A PH 20421A PH 29800 A PH29800 A PH 29800A PH 29800 A PH29800 A PH 29800A PH 20421 A PH20421 A PH 20421A
Authority
PH
Philippines
Prior art keywords
piperidinedione
derivatives
myocardium
presenting
protecting
Prior art date
Application number
PH29800A
Other languages
English (en)
Inventor
Claude Bernhart
Werner Cautreels
Patrick Gautier
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PH20421A publication Critical patent/PH20421A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PH29800A 1982-11-08 1983-11-08 Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them PH20421A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8218706A FR2535721A1 (fr) 1982-11-08 1982-11-08 Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives

Publications (1)

Publication Number Publication Date
PH20421A true PH20421A (en) 1987-01-05

Family

ID=9279000

Family Applications (1)

Application Number Title Priority Date Filing Date
PH29800A PH20421A (en) 1982-11-08 1983-11-08 Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them

Country Status (29)

Country Link
US (1) US4721710A (de)
EP (1) EP0110755B1 (de)
JP (1) JPS59161377A (de)
KR (1) KR900006721B1 (de)
AT (1) ATE22561T1 (de)
AU (1) AU565519B2 (de)
CA (1) CA1221967A (de)
CS (1) CS244681B2 (de)
DD (3) DD229407A5 (de)
DE (1) DE3366623D1 (de)
DK (1) DK511383A (de)
ES (1) ES527091A0 (de)
FI (1) FI79536C (de)
FR (1) FR2535721A1 (de)
GR (1) GR78747B (de)
HU (1) HU191494B (de)
IE (1) IE56209B1 (de)
IL (1) IL70099A (de)
MA (1) MA19948A1 (de)
NO (1) NO159852C (de)
NZ (1) NZ206177A (de)
OA (1) OA07582A (de)
PH (1) PH20421A (de)
PL (3) PL139946B1 (de)
PT (1) PT77607B (de)
SG (1) SG1989G (de)
SU (3) SU1333237A3 (de)
YU (3) YU221183A (de)
ZA (1) ZA838065B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668689A (en) * 1984-07-19 1987-05-26 National Research Development Corporation Glutarimide derivatives for treating oestrogen-dependent tumors
US5238947A (en) * 1990-04-12 1993-08-24 University Of Georgia Research Foundation, Inc. Synthetic piperidinediones with cytostatic activity
AU2012255860C1 (en) 2011-05-17 2015-12-10 Principia Biopharma Inc. Tyrosine kinase inhibitors
WO2012158795A1 (en) 2011-05-17 2012-11-22 Principia Biopharma Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
DK2710007T3 (da) 2011-05-17 2020-01-27 Principia Biopharma Inc Kinasehæmmere
EP2892900B1 (de) 2012-09-10 2017-08-16 Principia Biopharma Inc. Pyrazolopyrimidin-verbindungen als kinase-inhibitoren
US8957080B2 (en) 2013-04-09 2015-02-17 Principia Biopharma Inc. Tyrosine kinase inhibitors
SG11201606858RA (en) 2014-02-21 2016-09-29 Principia Biopharma Inc Salts and solid form of a btk inhibitor
ES2843323T3 (es) 2014-12-18 2021-07-16 Principia Biopharma Inc Tratamiento de pénfigo
TW201718572A (zh) 2015-06-24 2017-06-01 普林斯匹亞生物製藥公司 酪胺酸激酶抑制劑
IL263815B (en) 2016-06-29 2022-07-01 Principia Biopharma Inc Modified release formulations of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[4,3-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4 -Methyl-4-[4-(Oxtan-3-yl)piperazin-1-yl)pent-2-ananitrile

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664424A (en) * 1953-12-29 Dioxo-piperidines
GB1455687A (en) * 1972-12-28 1976-11-17 Aspro Nicholas Ltd Pharmacologically active 3-phenyl-3-aminoalkyl-2,6-dioxo-hydro genated pyridines
FR2467200A1 (fr) * 1979-10-11 1981-04-17 Clin Midy Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Also Published As

Publication number Publication date
DE3366623D1 (en) 1986-11-06
PT77607A (fr) 1983-12-01
IL70099A (en) 1987-10-20
EP0110755B1 (de) 1986-10-01
PL249750A1 (en) 1985-03-12
SU1333237A3 (ru) 1987-08-23
YU184185A (en) 1986-06-30
ES8406070A1 (es) 1984-07-01
DD229407A5 (de) 1985-11-06
IE832581L (en) 1984-05-08
OA07582A (fr) 1985-03-31
NZ206177A (en) 1985-11-08
CA1221967A (en) 1987-05-19
KR840006641A (ko) 1984-12-01
ES527091A0 (es) 1984-07-01
NO159852B (no) 1988-11-07
IE56209B1 (en) 1991-05-22
PT77607B (fr) 1986-03-18
IL70099A0 (en) 1984-01-31
SU1333238A3 (ru) 1987-08-23
FI79536C (fi) 1990-01-10
GR78747B (de) 1984-10-02
PL244462A1 (en) 1985-02-13
NO834057L (no) 1984-05-09
FI79536B (fi) 1989-09-29
NO159852C (no) 1989-02-15
DK511383D0 (da) 1983-11-08
YU184285A (en) 1986-06-30
ATE22561T1 (de) 1986-10-15
FR2535721B1 (de) 1985-05-17
PL140992B1 (en) 1987-06-30
CS244681B2 (en) 1986-08-14
US4721710A (en) 1988-01-26
SU1316558A3 (ru) 1987-06-07
DD229402A5 (de) 1985-11-06
EP0110755A1 (de) 1984-06-13
KR900006721B1 (ko) 1990-09-20
MA19948A1 (fr) 1984-07-01
DD219770A5 (de) 1985-03-13
FR2535721A1 (fr) 1984-05-11
FI834087A (fi) 1984-05-09
PL249749A1 (en) 1985-03-12
JPS59161377A (ja) 1984-09-12
YU221183A (en) 1986-06-30
PL140021B1 (en) 1987-03-31
HU191494B (en) 1987-02-27
FI834087A0 (fi) 1983-11-08
AU2089883A (en) 1984-05-17
ZA838065B (en) 1984-06-27
PL139946B1 (en) 1987-03-31
DK511383A (da) 1984-05-09
AU565519B2 (en) 1987-09-17
SG1989G (en) 1989-06-02

Similar Documents

Publication Publication Date Title
NZ218786A (en) 1,4 disubstituted piperidine derivatives and pharmaceutical compositions
PH20421A (en) Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity and pharmaceutical compositions containing them
JPS5665869A (en) Novel 22hydroxyalkyll3*4*55trihydroxyypiperidine compound* its manufacture and drug
NO822705L (no) Fremgangsmaate for fremstilling av 4-metyl-6-fenyl-pyridazinderivater
JPS56103168A (en) Thiazole derivative, its preparation, and antihistaminic agent containing the same
HUT50142A (en) Process for producing allyl-mercapto-acetyl-sidnonimine derivatives and pharmaceutical compositions containing them
FR2514765B1 (de)
PL286188A1 (en) Method of obtaining renine retarding aminooligohydroxy derivatives