US5186922A
(en)
*
|
1985-03-15 |
1993-02-16 |
See/Shell Biotechnology, Inc. |
Use of biodegradable microspheres labeled with imaging energy constrast materials
|
US5250285A
(en)
*
|
1985-05-08 |
1993-10-05 |
The General Hospital Corporation |
Hydroxy-aryl metal chelates for diagnostic NMR imaging
|
US5422096A
(en)
*
|
1985-05-08 |
1995-06-06 |
The General Hospital Corporation |
Hydroxy-aryl metal chelates for diagnostic NMR imaging
|
US4885363A
(en)
*
|
1987-04-24 |
1989-12-05 |
E. R. Squibb & Sons, Inc. |
1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
|
MX174467B
(es)
*
|
1986-01-23 |
1994-05-17 |
Squibb & Sons Inc |
1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos
|
GB8603537D0
(en)
*
|
1986-02-13 |
1986-03-19 |
Parker D |
Conjugate compound
|
US5342607A
(en)
*
|
1986-07-03 |
1994-08-30 |
Advanced Magnetics, Inc. |
Receptor mediated endocytosis type magnetic resonance imaging contrast agents
|
US5352432A
(en)
*
|
1986-07-03 |
1994-10-04 |
Advanced Magnetics, Inc. |
Hepatocyte specific composition and their use as diagnostic imaging agents
|
US5679323A
(en)
*
|
1986-07-03 |
1997-10-21 |
Advanced Magnetics, Inc. |
Hepatocyte-specific receptor-mediated endocytosis-type compositions
|
US5284646A
(en)
*
|
1986-07-03 |
1994-02-08 |
Advanced Magnetics Inc. |
Hepatocyte specific receptor mediated endocytosis type magnetic resonance imaging contrast agents
|
US5399340A
(en)
*
|
1987-09-24 |
1995-03-21 |
Schering Aktiengesellschaft |
Use of amide complex compounds
|
EP0381742B1
(fr)
|
1988-08-04 |
1996-06-19 |
Advanced Magnetics Incorporated |
Agents de contraste d'irm de type endocytose induits par recepteur
|
US5567687A
(en)
*
|
1989-03-06 |
1996-10-22 |
University Of Texas |
Texaphyrins and uses thereof
|
US4935498A
(en)
*
|
1989-03-06 |
1990-06-19 |
Board Of Regents, The University Of Texas System |
Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
|
US5599923A
(en)
*
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
US5559207A
(en)
*
|
1989-03-06 |
1996-09-24 |
Board Of Regents, University Of Texas |
Texaphyrin metal complex mediated ester hydrolysis
|
US5457183A
(en)
*
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
US5252720A
(en)
*
|
1989-03-06 |
1993-10-12 |
Board Of Regents, The University Of Texas System |
Metal complexes of water soluble texaphyrins
|
US5162509A
(en)
*
|
1989-03-06 |
1992-11-10 |
Board Of Regents, The University Of Texas System |
Process for preparing expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
|
US5808003A
(en)
*
|
1989-05-26 |
1998-09-15 |
Perimmune Holdings, Inc. |
Polyaminocarboxylate chelators
|
DE69022542T2
(de)
*
|
1989-05-26 |
1996-05-02 |
Akzo Nobel Nv |
Chelatierungsmittel zur bindung von metallionen zu proteinen.
|
US5292868A
(en)
*
|
1989-05-26 |
1994-03-08 |
Akzo N.V. |
Chelating agents for attaching metal ions to proteins
|
US6039931A
(en)
*
|
1989-06-30 |
2000-03-21 |
Schering Aktiengesellschaft |
Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
|
US5695739A
(en)
*
|
1989-06-30 |
1997-12-09 |
Schering Aktiengesellschaft |
Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production
|
DE69032761T2
(de)
*
|
1989-08-28 |
1999-04-22 |
The General Hospital Corp., Charlestown, Mass. |
Hydroxy-aryl metallchelate für bildformung zur nmr diagnose
|
US5594136A
(en)
*
|
1989-12-21 |
1997-01-14 |
Pharmacyclics, Inc. |
Texaphyrin solid supports and devices
|
WO1991010669A1
(fr)
*
|
1990-01-19 |
1991-07-25 |
Cockbain, Julian, Roderick, Michaelson |
Composes de chelation
|
GB9001245D0
(en)
*
|
1990-01-19 |
1990-03-21 |
Salutar Inc |
Compounds
|
US5124471A
(en)
*
|
1990-03-26 |
1992-06-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Bifunctional dtpa-type ligand
|
GB9007408D0
(en)
*
|
1990-04-02 |
1990-05-30 |
Nycomed As |
Compositions
|
JPH04154729A
(ja)
*
|
1990-10-16 |
1992-05-27 |
Nippon Mejifuijitsukusu Kk |
磁気共鳴造影剤
|
US5169944A
(en)
*
|
1991-04-12 |
1992-12-08 |
Board Of Regents Of The University Of Washington |
Methods and compositions for the enteral administration of hepatobiliary MRI contrast agents
|
US6875864B2
(en)
|
1991-08-01 |
2005-04-05 |
Bracco International B.V. |
Aminocarboxylate ligands having substituted aromatic amide moieties
|
US5562894A
(en)
*
|
1991-08-09 |
1996-10-08 |
Regents Of The University Of California |
Amino-acyl-type and catecholamine-type contrast agents for MRI
|
GB9120508D0
(en)
*
|
1991-09-26 |
1991-11-06 |
Nycomed As |
Diagnostic agents
|
US5565552A
(en)
*
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
US5888997A
(en)
*
|
1994-04-14 |
1999-03-30 |
Pharmacyclics, Inc. |
Radiation sensitization using texaphyrins
|
US5595726A
(en)
*
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
US5763172A
(en)
*
|
1992-01-21 |
1998-06-09 |
Board Of Regents, The University Of Texas System |
Method of phosphate ester hydrolysis
|
US5607924A
(en)
*
|
1992-01-21 |
1997-03-04 |
Pharmacyclics, Inc. |
DNA photocleavage using texaphyrins
|
US5385893A
(en)
*
|
1993-05-06 |
1995-01-31 |
The Dow Chemical Company |
Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
|
US5462725A
(en)
*
|
1993-05-06 |
1995-10-31 |
The Dow Chemical Company |
2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
|
US5798491A
(en)
*
|
1993-06-09 |
1998-08-25 |
Board Of Regents, The University Of Texas System |
Multi-mechanistic chemical cleavage using certain metal complexes
|
GB9314499D0
(en)
*
|
1993-07-12 |
1993-08-25 |
Nycomed Imaging As |
Method
|
US5358704A
(en)
*
|
1993-09-30 |
1994-10-25 |
Bristol-Myers Squibb |
Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents
|
WO1995027705A1
(fr)
*
|
1994-04-08 |
1995-10-19 |
Bracco International B.V. |
Composes amides aromatiques et leurs chelates metalliques
|
US5476644A
(en)
*
|
1994-04-13 |
1995-12-19 |
Sterling Winthrop Inc. |
Cyclic triamine chelating agents
|
US5969111A
(en)
*
|
1994-04-14 |
1999-10-19 |
Board Of Regents, The University Of Texas System |
Texaphyrins substituted with imidazole are provided
|
US5582814A
(en)
*
|
1994-04-15 |
1996-12-10 |
Metasyn, Inc. |
1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
|
US6693190B1
(en)
|
1994-05-11 |
2004-02-17 |
Bracco International B.V. |
Enhanced relaxivity monomeric and multimeric compounds
|
US5837866A
(en)
*
|
1994-09-21 |
1998-11-17 |
Board Of Regents, The University Of Texas |
Phosphoramidite derivatives of macrocycles
|
US5633354A
(en)
*
|
1994-09-21 |
1997-05-27 |
Pharmacyclics, Inc. |
Phosphoramidite derivatives of texaphyrins
|
US5672335A
(en)
*
|
1994-11-30 |
1997-09-30 |
Schering Aktiengesellschaft |
Use of metal complexes as liver and gallbladder X-ray diagnostic agents
|
TW319763B
(fr)
*
|
1995-02-01 |
1997-11-11 |
Epix Medical Inc |
|
US5591422A
(en)
*
|
1995-06-02 |
1997-01-07 |
Pharmacyclics, Inc. |
Texaphyrin complexes having improved functionalization
|
US5714328A
(en)
*
|
1995-06-07 |
1998-02-03 |
Board Of Regents, The University Of Texas System |
RNA photocleavage using texaphyrins
|
ATE268187T1
(de)
*
|
1996-04-01 |
2004-06-15 |
Epix Medical Inc |
Bioaktivierte diagnostische bilderzeugungskontrastmittel
|
DE19641197C2
(de)
*
|
1996-09-24 |
1999-02-18 |
Schering Ag |
Ionenpaare und ihre Verwendung als Kontrastmittel
|
DE19744004C1
(de)
*
|
1997-09-26 |
1999-07-22 |
Schering Ag |
Lipophile Metall-Komplexe für Nekrose und Infarkt-Imaging
|
US6495118B1
(en)
|
1997-09-26 |
2002-12-17 |
Schering Aktiengesellschaft |
Lipophilic metal complexes for necrosis and infarction imaging
|
EP1031354A3
(fr)
|
1999-01-19 |
2003-02-05 |
Rohm And Haas Company |
Agents de contraste polymère pour imagerie RMN
|
US7311893B2
(en)
*
|
2000-07-25 |
2007-12-25 |
Neurochem (International) Limited |
Amyloid targeting imaging agents and uses thereof
|
US7211240B2
(en)
*
|
2002-03-01 |
2007-05-01 |
Bracco International B.V. |
Multivalent constructs for therapeutic and diagnostic applications
|
US8623822B2
(en)
|
2002-03-01 |
2014-01-07 |
Bracco Suisse Sa |
KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
|
EP2014310B8
(fr)
|
2002-03-01 |
2012-12-26 |
Dyax Corp. |
Peptides de liaison KDR et VEGF/KDR et leur utilisation pour le diagnostic et la thérapie
|
US7794693B2
(en)
*
|
2002-03-01 |
2010-09-14 |
Bracco International B.V. |
Targeting vector-phospholipid conjugates
|
CA2513044A1
(fr)
|
2002-03-01 |
2004-08-05 |
Dyax Corp. |
Peptides de liaison kdr et vegf/kdr et leur utilisation a des fins diagnostiques et therapeutiques
|
US7261876B2
(en)
|
2002-03-01 |
2007-08-28 |
Bracco International Bv |
Multivalent constructs for therapeutic and diagnostic applications
|
US7303741B2
(en)
*
|
2002-09-23 |
2007-12-04 |
General Electric Company |
Systems and methods for high-resolution in vivo imaging of biochemical activity in a living organism
|
US7226577B2
(en)
|
2003-01-13 |
2007-06-05 |
Bracco Imaging, S. P. A. |
Gastrin releasing peptide compounds
|
ES2557286T3
(es)
|
2003-03-03 |
2016-01-25 |
Dyax Corp. |
Usos de péptidos que se unen específicamente al receptor del HGF (cMet)
|
BRPI0410635A
(pt)
|
2003-05-23 |
2006-06-13 |
Epix Pharm Inc |
isÈmeros enriquecidos e opticamente puros de ligantes de quelação e agentes de contraste
|
EP1654005A4
(fr)
*
|
2003-07-24 |
2011-06-15 |
Bracco Imaging Spa |
Compositions radiopharmaceutiques stables et methodes pour leur preparation
|
MX2007009354A
(es)
*
|
2005-02-03 |
2008-01-14 |
Epix Pharm Inc |
Metodos de perfusion en estado estable.
|
JP2009274962A
(ja)
*
|
2008-05-12 |
2009-11-26 |
Yoshihiro Ishikawa |
鉄サレン錯体、磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
|
WO2010107832A1
(fr)
|
2009-03-17 |
2010-09-23 |
Bracco Imaging Spa |
Analogues peptidiques de la lhrh-ii
|
WO2010121133A2
(fr)
|
2009-04-17 |
2010-10-21 |
The General Hospital Corporation |
Imagerie multimodale de fibrine
|
AR075900A1
(es)
|
2009-03-19 |
2011-05-04 |
Wyeth Llc |
Metodos para la preparacion de acidos (2-(8,9-dioxo-2,6-diazabiciclico (5.2.0) non-1(7)-en-2-il)etil) fosfonico y sus precursores.
|
US8378134B2
(en)
*
|
2009-09-30 |
2013-02-19 |
General Electric Company |
Hydroxylated contrast enhancement agents
|
US20110077417A1
(en)
*
|
2009-09-30 |
2011-03-31 |
General Electric Company |
Intermediates for Hydroxylated Contrast Enhancement Agents
|
US20110077396A1
(en)
*
|
2009-09-30 |
2011-03-31 |
General Electric Company |
Intermediates for hydroxylated contrast enhancement agents
|
US8722020B2
(en)
*
|
2010-03-31 |
2014-05-13 |
General Electric Company |
Hydroxylated contrast enhancement agents
|
US10471163B2
(en)
|
2013-09-13 |
2019-11-12 |
The General Hospital Corporation |
Activatable fibrin-binding probes
|
JP5806356B2
(ja)
*
|
2014-03-10 |
2015-11-10 |
株式会社Ihi |
鉄サレン錯体、磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
|
WO2015171543A1
(fr)
|
2014-05-05 |
2015-11-12 |
California Institute Of Technology |
Agents de capture mutants spécifiques d'akt, compositions et procédés d'utilisation et de préparation associés
|
US10471162B2
(en)
|
2014-06-20 |
2019-11-12 |
The General Hospital Corporation |
Collagen targeted imaging probes
|
WO2016149404A1
(fr)
|
2015-03-16 |
2016-09-22 |
California Institute Of Technology |
Agents de capture spécifiques de la neurotoxine botulique, compositions et méthodes d'utilisation et de préparation associées
|
CN115112898A
(zh)
|
2015-07-15 |
2022-09-27 |
加州理工学院 |
Il-17f-特异性捕获剂、组合物以及使用和制造的方法
|
CN114890941A
(zh)
|
2015-08-13 |
2022-08-12 |
通用医疗公司 |
用于mr分子成像的基于锰的螯合缀合物
|
CN115109120A
(zh)
|
2016-04-04 |
2022-09-27 |
英蒂分子公司 |
Cd8-特异性捕获剂、组合物及使用和制备方法
|
EP3519425B1
(fr)
|
2016-09-29 |
2024-02-28 |
Indi Molecular, Inc. |
Compositions pour la détection, l'inhibition et l'imagerie de l'indoléamine 2,3-dioxygénase 1 (ido1) et leurs méthodes de production et d'utilisation
|
WO2018085375A1
(fr)
|
2016-11-01 |
2018-05-11 |
Ohio State Innovation Foundation |
Procédés d'iodation de biomolécules
|
EP3638687A1
(fr)
|
2017-06-15 |
2020-04-22 |
Indi Molecular, Inc. |
Agents de capture spécifiques d'il-17f et il-17a, compositions et procédés d'utilisation et de production
|
US11919972B2
(en)
|
2018-11-02 |
2024-03-05 |
Regeneron Pharmaceuticals, Inc. |
Peptide libraries with non-canonical amino acids
|
WO2020097531A1
(fr)
|
2018-11-08 |
2020-05-14 |
Indi Molecular, Inc. |
Agents de capture théranostiques, compositions et procédés d'utilisation et de fabrication
|
WO2020186091A1
(fr)
|
2019-03-12 |
2020-09-17 |
Indi Molecular, Inc. |
Épitopes réticulés et leurs méthodes d'utilisation
|
US20200371101A1
(en)
|
2019-05-20 |
2020-11-26 |
Indi Molecular, Inc. |
Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (ido1)
|
US11414460B2
(en)
|
2019-07-19 |
2022-08-16 |
Institute For Systems Biology |
KRAS-specific capture agents, compositions, and methods of making and using
|
WO2021219871A2
(fr)
|
2020-04-30 |
2021-11-04 |
Aduro Biotech Holdings, Europe B.V. |
Anticorps anti-cd103
|
WO2022098743A1
(fr)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, imagerie et procédés thérapeutiques ciblant le récepteur 1 de folate (folr1)
|
WO2022098745A1
(fr)
|
2020-11-03 |
2022-05-12 |
Indi Molecular, Inc. |
Compositions, systèmes d'administration et méthodes utiles dans la thérapie antitumorale
|