LV11832B - O-acyl-4-phenyl-cyclohexanols, their salts, medicaments containing such compounds and their use, as well as a method of preparing them - Google Patents

O-acyl-4-phenyl-cyclohexanols, their salts, medicaments containing such compounds and their use, as well as a method of preparing them Download PDF

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Publication number
LV11832B
LV11832B LVP-96-439A LV960439A LV11832B LV 11832 B LV11832 B LV 11832B LV 960439 A LV960439 A LV 960439A LV 11832 B LV11832 B LV 11832B
Authority
LV
Latvia
Prior art keywords
cyclohexanol
trans
phenyl
dimethylaminomethylphenyl
group
Prior art date
Application number
LVP-96-439A
Other languages
English (en)
Latvian (lv)
Other versions
LV11832A (lv
Inventor
Woitun Eberhard
Maier Roland
Meller Peter
Hurnaus Rudolf
Mark Michael
Eisele Bernhard
Budzinski Ralph-Michael
Hallermayer Gerhard
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of LV11832A publication Critical patent/LV11832A/xx
Publication of LV11832B publication Critical patent/LV11832B/lv

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/24Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
LVP-96-439A 1992-11-20 1996-11-25 O-acyl-4-phenyl-cyclohexanols, their salts, medicaments containing such compounds and their use, as well as a method of preparing them LV11832B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4239150A DE4239150A1 (de) 1992-11-20 1992-11-20 O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
PCT/EP1994/001276 WO1995029148A1 (de) 1992-11-20 1994-04-25 O-acyl-4-phenyl-cyclohexanole, deren salze, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung
BR9408573A BR9408573A (pt) 1992-11-20 1994-04-25 O-acil-4-fenil-ciclohexanóis seus sais medicamentos contendo estes compostos e seu uso bem como para sua preparação

Publications (2)

Publication Number Publication Date
LV11832A LV11832A (lv) 1997-08-20
LV11832B true LV11832B (en) 1997-12-20

Family

ID=27160120

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-96-439A LV11832B (en) 1992-11-20 1996-11-25 O-acyl-4-phenyl-cyclohexanols, their salts, medicaments containing such compounds and their use, as well as a method of preparing them

Country Status (17)

Country Link
US (1) US5726205A (sk)
EP (1) EP0757669B1 (sk)
JP (1) JPH09512255A (sk)
AT (1) ATE173460T1 (sk)
BG (1) BG62961B1 (sk)
BR (1) BR9408573A (sk)
DE (2) DE4239150A1 (sk)
DK (1) DK0757669T3 (sk)
ES (1) ES2126759T3 (sk)
FI (1) FI964277A (sk)
LV (1) LV11832B (sk)
NO (1) NO307175B1 (sk)
NZ (1) NZ266138A (sk)
PL (1) PL179890B1 (sk)
RU (1) RU2130921C1 (sk)
SK (1) SK281213B6 (sk)
WO (1) WO1995029148A1 (sk)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4239150A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE19626771C2 (de) * 1996-07-03 1998-09-24 Merck Patent Gmbh 4-(4-Oxocyclohexyl)-benzamide
FR2754255B1 (fr) * 1996-10-08 1998-10-30 Synthelabo Procede de preparation de derives de trans-4-(4- aminomethylphenyl) cyclohexanols
DE19704401C1 (de) * 1997-02-06 1998-05-07 Thomae Gmbh Dr K Verfahren zur Herstellung von trans-4-(4-Aminomethyl)phenyl-cyclohexanolen
DE19754795A1 (de) 1997-12-10 1999-06-17 Boehringer Ingelheim Pharma Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
AU2003218004A1 (en) * 2002-03-12 2003-09-29 Merck & Co., Inc. Drug combination therapy
AU2008345573B2 (en) 2007-12-20 2013-12-19 Envivo Pharmaceuticals, Inc. Tetrasubstituted benzenes
US20150150954A1 (en) 2012-07-04 2015-06-04 The University Of Sydney Treatment of inflammatory skin disorders
AU2014391082B2 (en) 2014-04-16 2020-04-09 Zz Biotech Llc Treatment of abnormal cutaneous scarring

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431564A (en) * 1981-05-01 1984-02-14 Chisso Corporation Liquid-crystalline biphenyl or terphenyl derivatives
US5391571A (en) * 1989-11-15 1995-02-21 American Home Products Corporation Cholesterol ester hydrolase inhibitors
CA2044533A1 (en) * 1990-06-29 1991-12-30 Philippe Guerry Substituted aminoalkylbiphenyl derivatives
DE4239151A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K N,N-Disubstituierte Arylcycloalkylamine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4239150A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
LV11832A (lv) 1997-08-20
FI964277A0 (fi) 1996-10-24
DK0757669T3 (da) 1999-08-02
EP0757669A1 (de) 1997-02-12
DE4239150A1 (de) 1994-05-26
ATE173460T1 (de) 1998-12-15
NO964525D0 (no) 1996-10-24
RU2130921C1 (ru) 1999-05-27
SK281213B6 (sk) 2001-01-18
AU6721194A (en) 1995-11-16
SK135996A3 (en) 1997-05-07
BG62961B1 (bg) 2000-12-29
EP0757669B1 (de) 1998-11-18
BR9408573A (pt) 1997-08-26
US5726205A (en) 1998-03-10
AU685118B2 (en) 1998-01-15
NO307175B1 (no) 2000-02-21
BG100912A (en) 1997-07-31
JPH09512255A (ja) 1997-12-09
PL179890B1 (pl) 2000-11-30
FI964277A (fi) 1996-10-24
NO964525L (no) 1996-10-24
ES2126759T3 (es) 1999-04-01
DE59407317D1 (de) 1998-12-24
WO1995029148A1 (de) 1995-11-02
NZ266138A (en) 1998-03-25
PL316964A1 (en) 1997-03-03

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