LV10895B - Arylpyrrole derivatives, struggle method against insekts, ticks and nematodes, process for preparing of derivatives of arylpirrole - Google Patents

Arylpyrrole derivatives, struggle method against insekts, ticks and nematodes, process for preparing of derivatives of arylpirrole Download PDF

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Publication number
LV10895B
LV10895B LVP-93-1061A LV931061A LV10895B LV 10895 B LV10895 B LV 10895B LV 931061 A LV931061 A LV 931061A LV 10895 B LV10895 B LV 10895B
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compound
group
nematodes
substituted
formula
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LVP-93-1061A
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LV10895A (lv
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Dale Gordon Brown
Jack Kenneth Siddens
Robert Eugene Diehl
Donald Perry Wright Jr
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American Cyanamid Co
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

LV 10895 nPOM3BOflHblE ΑΡΜΠΠΜΡΡΟΙΙΑ, ΟΠΟΟΟΒ BOPbBbl C HHCEKTmiMflAMU, AKAPMlļMflAMM M HEMATOflAMM, ΟΠΟΟΟΒ ΠΟίΙΥΜΕΗΜΡ nPOM3BOflHblX ΑΡΜ/1ΠΜΡΡΟ/1Α
OnncaHHe
HacTOfliiļee M3o6peTeHMe othocmtch k ΗβκοτορωΜ hobum npon3BOflHb»M apunnMppona, KOTopbie o6xiafla»0T oneHb BbicoKofi 3φφβΚΤΜΒΗθση>ΙΟ B ΚΘΜΘΟΤΒΘ MHCeKTMLļMflHblX, aKapMLļMflHblX M HeMaT04MflHbix areHTOB, KOTopbie MoryT ncno/ib30BaTbcn ann ymiMTO)KeHMfl HBceKOMbix, KneLLļeii vt HeMaTOfl μ απη 3amnTbi ποπθ3ηνχ pacTeHnii, xax b CTaflMu pocTa, τθκ m b CTaflun c6opa γροχοα, προτΜΒ yKaaaHHbix bmaob BpeflMTeneii. Hacofliiļee μ3ο6ρθτθημθ τθιοκθ othocmtcb k cnoco6aM nonyMeHHfl yKa3aHHbix npoM3BOflHbix apnnnnppona. 1
HoBbie npon3BOflHbie apurinuppo/ia comacHO HacTOBUļeMy Μ3ο6ρβτβΗΜΐο οτβθη3Κ)τ npeACTaeneHHOM ημ>κθ cTpyKTypHOM c|3opMyne I:
0) B κοτοροίί X ΠρβΑΟΤΘΒΠΒΘΤ ΟΟδΟΜ BOflOpOfl, φΤΟρ, ΧΠΟρ, 6pOM, MOA HJ1M CF3 ; Y npeACTaB/ifleT οοδοίί BOAopoA, φτορ, χπορ, δροΜ, moa, CF3 mjim CN; W πρβΑΟτβΒΠΒβτ οοδοίί CN nnn N02; A npeACTaBJi«eT οοδοίί anmn, coAeparaiAMM ot 1 a° 4 θτομοβ ymepoAa, 3aMeiLļeHHbiii 4 βτομβμμ ranoreHa, oahom i4naHorpynnoM, oahom anKOKCMrpynnoM, coAep>Kauļeii ot 1 ao 4 θτομοβ yrnepoAa, 3aMeiiļeHHOii 1-3 aTOMaMM ranoreHa min AayMfl anKOKcnrpynnaMH, bo3Mo>kho AononHMTenbHo 3aMemeHHbiMn 1-3 aTOMaMM ranoreHa, oahom Kap6anKOKCMrpynnoM, coAep>KaiAeM ot 1 ao 4 3tomob yrnepoAa, oahom anKMnKap6oHMnoKCMrpynnoM, coAepJKameM ot 1 ao 6 θτομοβ yrnepoAa, oahom anKeHM/iKap6oHMnoKCMrpynnoM, coflep^aiiļeM ot 2 ao 6 3tomob yrnepoAa, oahom 6eH3onKap6oHMnoKCMrpynnoM, MnM χηορ-, Α^χηορ-, mjim MeTMn3aMeiiļeHHOM 6eH3om<ap6oHMnoKCMrpynnoii; L npeACTaBnneT οοδοίί boaopoa, φτορ, χηορ, MnM δροΜ; Μ μ R npeACTaBnneT οοδοίί Kax<AbiM ηθ33Βμομμο Apyr ot Apyra boaopoa, anKMnbHyio rpynny, coAep>Kanyio ot 1 ao 3 θτομοβ ymepoAa, anKOKCMJibHyio rpynny, coAep>KamyK) ot 1 ao 3 btomob ymepoAa, anKMnTMorpynny, coAep>KatAyio ot 1 ao 3 3tomob yrnepoAa, anκMncynbφMHMnbHyκ) rpynny, coAap>KaLLļy}o ot 1 ao 3 btomob yrnepoAa, anκMncynbφoHMnbHy^o rpynny, C0Aep>KaiAyK> ot 1 ao 3 btomob yrnepoAa, LļMaHorpynny, φτορ, χηορ, δροΜ, moa, HMTporpynny, rpynny CF3i RiCF2Z, R2CO MJIM NR3R4 , ΓΑβ Μ M R HaXOAflTCB B CMe>KHblX ποηο>κβΗΜΒΧ μ βμθοτθ c θτομθμμ yrnepoAa, c κοτορωΜΜ ohm οοθαμηθην, MoryT o6pa30BbiBaTb KonbLļo, b κοτοροΜ MR npeACTaBnflioT οοδοίί CTpyicrypy: 2 LV 10895
-0CH20-, -0CF20- nnn Z npeflCTaBrifleT co6oPi S(0)n μπμ O;
Ri npeflCTaB/iaeT co6om BOflopofl, φτορ, CHF2 ,CHFCI, CF3; R2 npeflCTaBrmeT co6oii ajiKnnbHyK) rpynny, coflep>Kainyio ot 1 flo 3 araMOB yrnepofla, aJiKOKCMJibHyio rpynny, coflep>Kainyio ot 1 flo 3 btomob ymepofla, ΜΠΜ NR3R4; R3 npeflCTaBnneT co6oii ar)KMnbHyio rpynny, coflep>Kamyto ot 1 flo 3 btomob yrnepo,qa; R4 npeflCTaB^fleT co6oii aTOM eoflopofla, a/iKHfibHyK> rpynny, coflep>Kainyio ot 1 ,qo 3 aTOMOB yrnepofla, min R5CO; R5 npeflCTaBJineT co6oii aTOM eoflopofla, anKMnbHyio rpynny, coflep>i<ainyio ot 1 flo 3 aTOMOB yrnepofla, m n npeflCTaBnaeT co6ofi Lļenoe hmcjio, paBHoe 0, 1 mjim 2;
ripu tom ycnoBMM, mto Korfla X μ Y npeflCTaBJinioT co6om eoflopofl, a A npeflCTaB/iiieT co6ofi ajiKWibHyio rpynny, coflep>Kainyio ot 1 flo 3 3Tomob /
L
R yrnepofla, 3aMeiiļeHHyio oahoū LļnanorpynnoMI to 3aMecTMTenb flOJDKeH 6blTb 33φΐΊKCHP0B3H B OflHOM M3 flyX ΠΟΠΟ>ΚβΗΜΜ nMppOJlbHOlO KOJlbLļa, COCeflHMX C 3T0M0M a30Ta.
I~pynny npeflnoHTMTejibHbix HOBbix npon3BOflHbix apnnnnppona cornacHo HacTo?uiļeMy Μ3θδρβτβΗΜΚ) cocTaBnaioT οοθαμηθημα, οτβθηθκμαμθ oāuļeii φopMyne II L &
R W γ (II) b κοτοροίί A, L, M, R, W, X μ Υ μμθιοτ tot >κθ CMbic/i, mto m paHee. 3
flpyry»o rpynny npeflnoMTHTe/ibHbix ηοβμχ npoM3B0flHbix apnnnnppojia comacHo HacTOflUļeMy μ3ο6ρθτθημιο οοσίΌΒΠΗίοτ coeflMHeHMfl, OTBenaiOLUMe οδιμβίί φopMyJ^e III
(III) b κοτοροΜ A, L, M, R, W, X μ Υ μμθιοτ tot >κθ CMbicn, hto m panee.
Euļe oflHy rpynny npeflnoHTMTeribHbix HOBbix npoM3BOflHbix apnnnnppoJia cornacHo HacTomiļeMy μ3ο6ρθτθημιο cocTaBJiflioT οοθαμηθημη, OTBenaiomMe o6uļeii φopMyJ^e IV
(IV) b κοτοροΜ A, L, M, R, W, X μ Υ μμθιοτ tot >κθ CMbicn, mto m paHee.
Euļe oflHy rpynny npeflnoHTMTeribHbix HOBbix npoM3BOflHbix apM/inuppo/ia cornacHo HacTOiuneMy Μ3θ6ρβτβΗΜΐο οοοτθβπηιοτ coeflMHeHMfl, OTBeMatoiiļMe o6mefi φopMyne V
M
(V) 4 LV 10895
b κοτοροίί A, L, M, R, W, X n Υ μμθιοτ tot >κθ cMbicn, mto h paHee; n euļe 0flHy rpynny npe/ļnoHTMTenbHbix ηοβηχ npon3BOflHbix apnnnnppona cornacHO HacTOfliiļeMy M3o6peieHnio cocTaBJiiuoT οοθαμηθημη, OTeenaraiAMe o5ll1hm φοριν^ηβΜ VI n VII
VI VII b κοτοροίί A, L, M, R,W,XmY μμθιοτtotme CMbicn, hto m paHee. npeflnOMTMTeJlbHblMM npOH3BOflHblMM θρΜΟΠΜρρΟΟΘ θ6ΐ11βίί 0OpMyjlbl I comacHO HacTomiļeMy Μ3θδρβτβΗΜΐο ABnaiOTCH οοθαμηθημα, b κοτορωχ: W npeflCTaBnaioT οοδοίί iļMaHo- min HMTporpynny, L npeflCTaBJintoT οοδοίί θτομ eoflopofla, M npeflCTaBJiflioT οοδοίί Bo/ļopo/ļ, φτορ, χηορ min δροΜ, X μ Y Ka>«flbiti npeflCTaBrmeT οοδοίί χηορ, 6poM, min CF3, R npeflCTaBnneT οοδοίί φτορ, χηορ, δροΜ, CF3 μπμ OCF3. npeflnOMTMTeJlbHblMM npOH3BOflHblMM βρΜΠΠΜρρΟΠβ ΟδίΑβίί φορΛ/^ΠΗ II cornacHO HacTomi^eMy Μ3θδρβτβΗΜΐο «ΒηηιοτοΗ οοθαμηθημα, κοτορωβ ΟΟΟδΘΗΗΟ 3φφβΚΤΜΒΗΗ Β ΚΘΗΘΟΤΒβ MHCeKTHI4MflHblX, aKapHLļMflHblX H/MOM HeMaTOLļMflHbix cpeflCTB, b KOTopbix: L npeflCTaBJifiioT co6oii aTOM BO,qopo,qa, φτορ, χηορ μπμ 6poM, M npeflCTaBnnioT οοδοίί eoflopofl, φτορ, χηορ nnw δροΜ, R npeflCTaBnneT οοδοίί φτορ, χηορ, δροΜ, CF3 nnn OCF3, W npeflCTaBnBīoT οοδοίί LļnaHorpynny, X μ Υ KajKflbiii npeflCTaBneeT οοδοίί He3aBMCMMo flpyr οτ flpyra χηορ, δροΜ, Unu CF3. flpyrnMM npe/ļnoMTMTenbHbiμm npon3BOflHbiMM apnnnnppona οδίμβίί φopMynbι II cornacHO HacTOflineMy Μ3θδρβτΘΗΜκ>, βνοοκοθΦΦθκτμβη^μμ β KasecTBe MHceKTmļM/ļHbix, aKapm4MflHbix n/nnn HeMaTOLļHflHbix cpeflCTB, nenflioTCfl οοθαμηθημα, β κοτορ^χ: 5 L npeflCTaBJiflioT οοδοίί θτομ eoflopofla, M npeflCTaB/iiiioT οοδοίί βοβοροΑ, φτορ, χπορ min δροω, R npeflCTaBnfleT οοδοίί φτορ, χπορ, δροΜ, CF3 μπμ OCF3, W npe/ļCTaennioT οοδοίί HMTporpynny, X npeflCTaBnneT οοδοίί χπορ, 6poM μπμ CF3, h Y npeflCTaBnneT οοδοίί eo/ļopofl, χπορ, 6poM, vtm CF3. B KaMecTBe npuMepoB, nnnKDCTpnpytoiiļMX Ηβκοτορι>ΐΘ MHceKTULļMflHbie, aKapMLļnflHbie m HeMaTOLļUflHbie npoM3BOflHbie apnnnnppona, mo>kho npHBecm cneflyK>mne οοθαμηθημπ: [2,3-ΑΜΧπορ-4-ΐ4Μ3Ηθ-5-(3,4-/1ΜχπορφθΗΜΠ)ΠΜρρπο-1 'iin]TpMMeTMnyKcycHan KMcnoTa, MeinnoBbiii 3φΜρ, TeMnepaTypa ππθβπθημπ 143-145 °C; 4,5-ΑΜΧΠορ-1-(οκοΜΜβΤΜπ)-2-(α,α,α-τρΜφτορ-π-τοπΜη)πΜρροπ- 3- Kap6oHMTpnn, aiļeTaT (cno>KHbiii 3φΜρ); 4- 6ρ0Μ-2-(Π-ΧΠ0ρφβΗΜΠ)-1-0Κ0ΜΜΘΤΜΠ-5-(τρΜφΤ0ρΜβΤΜ/ΐ)ΠΜρρ0/1- 3- Kap6oHMTpnn, cno>KHbiii 3φιιρ TpnMemnyKcycHoii κμοποτη, TeMnepaTypa nnaBneHMn 127,5 °C; 4- 5ρθΜ-2-(3,4-ΧΠθρφθΗΜΠ)-1-ΟΚΟΜΜΘΤΜ/1-5-(τρΜφΤθρΜΘΤΜΠ)ΠΜρρθ/1- 2- Kap6oHmpun, cno>KHbiii 3φιιρ TpnMeTnnyKcycHOM KucnoTbi, TeMnepaTypa ππθβπθημπ 93-94 °C; 3,4-ΑΜ6ρθΜ-5-(Π-ΧΠθρφθΗΜΠ)-1-ΟΚΟΜΜΘΤΜΠΠΜρρθΠ-2-Κ3ρ6θΗΜΤρΜΠ, cno>KHbiM 3φΜρ TpMMeTMJiyKcycHoii KMciioTbi, TeivmepaTypa ππθβπθημη 130- 132 °C; [2,3-ΑΜΧπορ-4-ψΐ3Ηθ-5-(α,α,α-τρΜφτορ-π-το/ΐΜπ)πΜρροπ-1-Μπ]-TpnMeTnnyKcycHan κμοποτθ, ΜθΤΜΠοβωίί 3φιιρ, TeMnepaTypa nnaBneHMJi 153-157 °C; 3- 6ρθΜ-5-11Μ3ΗΟ-4-(3,4-ΧΠθρφθΗΜΠ)-2-(τρΜφΤθρΜΘΤΜΠ)ΠΜρρθΠ- 1- aneTOHMTpnn, TeMnepaTypa ππθβπθημπ 95-97 °C; 2.3- ΑΜΧΠθρ-4-Ι1Μ3ΗΟ-5-(α,α,α-ΤρΜφΤθρ-Π-ΤΟΠΜΠ)ΠΜρρθΠ-1-3Ι1ΘΤΟΗΜΤρΜ/1, TeMnepaTypa ππθβπθημπ 137,5-139 °C; 2.3- ΑΜΧΠ0ρ-4-Ι1Ι13Η0-5-(3,4-ΧΠ0ρφβΗΜΠ)ΠΜρρ0Π-1-3Ι1βΤ0ΗΜΤρΜΠ,
TeMnepaiypa nnaBJieHnn 197-199 °C; 2- [(3,4-ΑΜΧΠθρφΘΗΜΠ)-3-ΗΜΤρθ-5-(τρΜφΤθρΜΘΤΜΠ)ΠΜρρθΠ-1-ΜΠ]6ΘΗ3θίίΗ3Π KucnoTa, μθτμποβνμ 3φκρ; 6 LV 10895 3- 6ροΜ-5·(π-6ροΜφβΗΜη)-4-ΐ1Μ3Ηο-2-(τρΜφτορΜβτΜ/ι)πΜρροη-1-aiļeTOHMTpnn, TeMnepaTypa π/ιθβπθημα 110,5-113 °C; [3-6ροΜ-5-χπορ-4-ΐ1Μ3Ηθ-2-(314-χηορφβΗΜη)πΜρροη-1-Μη]-TpnMeTkmyKcycHa?i KucnoTa, μθτμ/ιοβημ 3φΜρ, TeMnepaTypa nnaBJieHMfl 119-122 °C; [2,3-ΑΜΧΓΐορ-4-ΐ4Μ3Ηθ-5-(α,α,α-τρΜφτορ-π-τοηΜη)ΠΜρροπ-1 -nn]-1 -n-xnop6eH30MHafl KucnoTa, MeTMJioBbiii 3φκρ; 4- 6ρ0Μ-2-(π-ΧΠ0ρφβΗΜ/ΐ)-1-0ΚαΐΜΘΤΜΓΙ-5-(τρΜφΤ0ρΜΘΤΜΡ)ΠΜρρ0Π-3-Kap6oHMTpnn, n-xnop6eH3oaT (cno>KHbiii 3φΐφ); 2,3-ΑΜΧΡορ-5-(π-χπορφΘΗΜη)-4-ΐ1Μ3ΗθΠΜρροη-1-3μβτοΗΜτρΜ/ι, TeMnepaTypa rviaBJieHMfl 175-177 °C; [2-(3,4-Χ/1θρφβΗΜ/ΐ)-3-ΗΜΤρθ-5-(τρΜφΤθρΜβΤΜ/ΐ)ΠΜρρθ/7-1-Μ/ΐ]-TpnMeTMJiyKcycHa5i KucnoTa, ΜβΤΜ/iOBbiM 3φκρ, TeMnepaiypa n/iaB/iemia 116-119 °C; 3-6ρθΜ-2-(Π-Χ/1θρφΘΗΜη)-1-[2,2,2-ΤρΜφΤθρ3ΤΟΚΟΜ)ΜβΤΜΠ]-5- (τρΜφΤθρΜΘΤΜΓΐ)ΠΙ/ΐρρθΠ-3-Κ3ρ6θΗΜΤρΜη, Μ 3-5ροΜ-5-χηορ-(π-χηορφβΗΜπ)-4-ΐ1Μ3ΗθΠΜρρο/ι-3-κ3ρ6θΗΜτρΜη,
TeMnepaTypa π/iaBneHMn 144-150 °C.
Cnocoābi nonyHeHM« npon3BOflHbix apminnppo.na φορι^/ιω I, b κοτοροΐί A npeflCTaBJiaeT co6o£i aTOM Boflopofla, onncaHbi b coBMecTHoii eeponeiicKoii naieHTHoCi ny6nnKaLļnn # 0303863. nonyHeHMe 3aMeiiļeHHbix no a30Ty npoM3BOflHbix apwmnppona φορΜγ/^ι μο>κθτ 6biTb ocyuļecTB/ieHO b pe3y/ibTaie peaKLļnn cooTBeTCTByioinMM o6pa30M 3aMemeHHoro apnnnnppona φορι^/ιω I, b κοτοροίί A npeflCTaBnneT cočoii aTOM Boflopoaa, a L, M, R, W, X μ Υ μμθιοτ TOT >Ke CMbICJl, HTO Μ paHee, C COOTBeTCTByK)UļMM ΘΓΘΗΤΟΜ 3/1ΚΜΠΜρθΒ3ΗΜί1 Μ noAxoflnu4MM οοηοβθημθμ, Hanpmviep xjnopMewibHbiM ranoreHanKMnbHbiM (cx)flep>KainMM ot 1 flo 4 θτομοβ yrnepoAa b anKMnbHoii MacTM) npocTbiM 3φΜρθΜ M rMflpMflOM KaJIMfl. 3ia peaKLļMB ΠρΜΒΟΑΜΤ K ΠΟΙ^ΗΘΗΜΚ) apminuppona, MMetouļero τβ >κθ βθμθοτμτθπμ, mto m μοχοαηημ npoflyicT, οαηθκο κροΜβ τογο, 3aMeuļeHHoro no a30Ty ranoreHanKOKcmvieTunbHbiM paflMKanoM (coflep^auļMM ot 1 flo 4 btomob yrnepofla b anKunbHofi nacTM). B aHanoruMHoii peaKLļnn xnopMeTwibHbiii ranoreHanKMnbHbiM npocTofi 3φΜρ, 7 co,qep>KainMM οτ 1 ao 4 θτομοβ ymepofla b a/iKM/ibHOM MacTM, 33μθηβκ>τ Ha α-δροΜβμβτοΗΜτρΜίΐ m nonyMaioT npoM3BOflHbie apnnnnppona φορι^πω i c aLļeTOHMTpMJlbHblM 33ΜΘΟΤΜΤΘΠβΜ npH θ30Τβ. PeaKLļMfl ΜΟ>ΚβΤ 6blTb nponrmiocTpMpoBaHa cne,qyioiiļeii οχθμομ:
b κοτοροίί L, M, R, W, X μ Υ μμθιοτ tot >κθ CMbicn, mto μ b npMBefleHHOM Bbiiiie onucaHUM φορΜνπω I, a A npeflCTaBJiaeT οοδοίί 1) ranoreHanKOKCMMeTMnbHbiPi paflMKan, coflep>KauļMii ot 1 flo 4 θτομοβ ymepofla b ajiKMJībHoCi MacTH, m 2) rpynny CH2CN. Ημ>κθ npMBefleHbi npMMepbi, MfintocTpMpyiomMe npMBeAeHHyio Bbiiue cxeMy peaKLļkiH, b κοτορωχ onncaHbi cnoco6bi no/iyMeHMa προΜΜχ οοθαμηθημμ cornacHo HacToBiiļeMy μ3ο6ρθτθημκ>, κοτορωβ κοηκρθτηο b ημχ ΗΘ OnMCaHbl. npon3BOflHbie apn/innppona cornacHo HacToaiiļeMy μ3ο6ρθτθημκ> BB/lHIOTCa θφφβΚΤΜΒΗΝΜΜ C TOM KM 3ρβΗΜΑ yHMMTO>KeHMB HaCeKOMblX, Kneuļeii μ ηθμθτοα. YKa3aHHbie οοθαμηθημη θΦΦθκτμβηβι TaioKe c tomkm 3peHMii 3aiiļMTbi pacTyuļMx v\m co3peBa(ouļMX pacTeHMii ot yKa3aHHbix τμποβ BpeflMTeneii.
Ha npaKTMKe o6bNHo οτ πρΜΜβρΗο 10 M./ļ. flo npMMepHo 10 000 M.fl., npeflnoHTMTenbHO ot 100 ao npMMepHo 5 000 M.fl. npoM3BOflHbix apMJīnMppona φορι^ΠΝ I (b 3to κοπμηθοτβο βχοαβτ βοθ Μ30Μβρω apM/īnMppona φopMyn II, III, IV, V, VI μ VII) AMcneprMpyioT β BOfle mjim ApyroM fleiiieeoM >κμακομ ηοομτθπθ, m yKa3aHHoe κοπμηθοτβο ηβ/ιβθτοη
ΘφφΘΚΤΜΒΗΗΜ ΠρΜ ΠρΜΜΘΗΘΗΜΜ Ha p3CTyiHMX ρβΟΤΘΗΜΒΧ, C03peBUJMX pacTeHnax mjim πομβθ, na κοτοροίί npoM3pacTaioT yKa3aHHbie pacTeHMa pjia 8 LV 10895 ΜΧ 3aLU,HTbl OT Π0ρ8>ΚΘΗΜΠ HaC6K0MblMM, ΚΠΘίμθΜΜ Μ/ΜΠΜ ΗΘΜ3Τ0Α3ΜΜ. YKa3aHHbie οοθαμηθημη ηβ/ιαιοτοπ τθιοκθ ποπθ3ηημμ c τοηκμ 3ρθημπ 3ammbi τορφβ οτ nopatteHua βρθαμτθπημμ, τθκμμμ κθκ πμημηκμ >κγκοΒ, 3eMJiiiHbie icnonbi μ mm ποαο6ηβιμμ HaceKOMbiMM. npoM3BOAHbie apMJīnMppona <ļ>opMynbi I cornacHO HacTo$UAeMy Μ3θδρβτβΗΜΚ) abiihiotch TaioKe θΦΦθκτμβηνμμ c τοηκμ 3ρθημλ Υημητοκθημπ HaceKOMbix, ηθμ3τοα m Kneiiļeti npn μχ πρμμθηθημμ Ha JIMCTBe paCTeHMM M/MJ1M Ha ΠΟΜΒΘ ΜΠΜ B BOAe, B KOTOpOM BbipaULļMBaiOT yKa3aHHbie pacTeHMfl, πρΜ μχ πρμμθηθημμ b κο/ιμηθοτβθ, o6ecnewMBa>oiAeM ΗΘΓΙΜΗΜΘ 3ΚΤΜΒΗ0Γ0 ΚΟΜΠΟΗΘΗΤΘ ΠρΜ Α03Θ OT ΠρΜΜβρΗΟ 0,100 ΚΓ/ΓΒ β,Ο ΠρΜΜβρΗΟ 4,0 ΚΓ/ra. ΟΜΘΒΜΑΗΟ, ΠΎΟ μ 6onblliMe ΚΟΠΜΗΘΟΤΒΘ ΠρθΜ3ΒΟΑΗΗΧ apMJīnMppona φορΜγπω I Μοιγτ Mcnonb30BaTbcn μη* 3aiiļHTbi pacieHMM οτ HaceKOMbix, ηθμθτοα μ κ/ίθιαθμ, οαηθκο 6onee βνθοκμθ A03bi o6wmho BBJiaiOTCn HeHy)KHblMM M M3J1MLUHblMM. ΧοτΗ npoM3BOAHbie apMnnMppona comacHo ΗβοτοπιμθΜγ Μ3θ6ρβΤ ΘΗΤΙΟ ΠΒ/ΊΠΙΟΤΟΠ ΘφφθΚΤΜΒΗωΜΜ ΑΠ« γΗΜΜΤΟ)ΚΘΗΜΗ HaceKOMblX, ΗΘΜ3Τ0Α Μ KJiemeM ΠρΜ ΜΧ ΠρΜΜΘΗΘΗΜΜ ΟΘΜΜΧ ΠΟ Οθ6θ, ΜΧ ΜΟ)ΚΗΟ ΤΘΙΟΚΘ MCnonb30B3Tb Β ΟΟΗΘΤΘΗΜΜ C ΑΡΥ™ΜΜ 6MOaKTMBHblMM ΧΜΜΜΙΟΤΘΜΜ, ΒΚΠΙΟΜΘΠ ΠρΟΗΜΘ ΜΗΟΘΚΤΜμΜΑΝ, HeM3T0LļMAbl Μ aKapMLļMAbl. TaK HanpMMep npoM3BOAHbie apMnnMppona cornacHO HacTonmeMy Μ3ο6ρθτθημκ> MoryT θφφθΚΤΜΒΗΟ MCnonb30BaTbCH Β ΟΟΗΘΤΘΗΜΜ MJ1M B KOM6MHaLļMM C φθθφ3Τ3ΜΜ, Kap6aMaTaMM, ΠΜρθΤρθΜΑ3ΜΜ, φθρΜ3ΜΜΑΜΗ3ΜΜ, ΧΠΟρΜρΟΒβΗΗΗΜΜ ymeBOAOpOAaMM, Γ3/10ΓΘΗ6θΗ30ΠΜ0ΗΘΒΜΗ8ΜΜ m mm nOAOOHbIMM peaKTMBaMM. ΠρβΑΠΟΗΤΜΤΘΑΒΗΟ ΟΤΜΘΜΘΗΗΝΘ BblUJe npOM3BOAHbie βρΜΑΠΜρρΟΑΘ MoryT 6biTb npMroTOBneHbi b BMAe cyxMX φορΜΟΒθΗΗΗχ rpaHyn, cbinyHMx KOMno3MLļMM, rpaHynnpHbix peLļenTyp, ποροιυκοΒ a^ pacTBopeHMn, nopOUJKOB ΑΠΑ ρβΟΠωηθΗΜΠ, ΚΟΗμθΗΤρΜρΟΒβΗΗΜΧ AyCTOB, MMKp03MynbCMM M ApyrMX noAo6Hbix ρθμβπτγρ, κοτορωβ MoryT BBOAMTbcn b noHBy, boay m/mtim Ha riMCTBy m o6ecneHMBaTb Tpe6yeMyio cTeneHb 3auļMTbi pacTeHMM. B mmcao ποΑοδπωχ ρβμβπτγρ βχοα^τ οοθαμηθημη comacHo ΗβοτοηιμβΜγ Μ3θδρθΤΘΗΜΚ), CMeiliaHHbie C MHepTHbIM, npMrOAHbIM pņn φ3ρΜ3Ι4ΘΒΤΜΗΘΟΚΟΓΟ ΜΟΠΟΠΒ30Β8ΗΜΠ TBepAbIM MJ1M )KMAKMM pa36aBMTeneM. 9
EaK HanpMMep ποροιυκΜ pacTBopeHnn, AycTbi m KOHLjeHTpaTbi AycTOB comacHo HacTosmeMy μ3ο6ρθτθημ»ο MoryT 6biTb no/iyHeHbi b pe3ynbTaie CMeujMBaHMfl ot npuMepHO 3 eec. % flo npMMepHO 20 eec. % npon3BOflHbix apMJīnMppona 4>opMy/ibi I c ot npMMepHO 3 eec. % flo npMMepHO 20 eec. % τβθραογο θημοηηογο ποβθρχηοοτηο-θκτμβηογο areHTa.
OaHMM M3 ΠΟΑΧΟΑΛΙΑΜΧ aHMOHHblX n0B8pXH0CTH0-aKTMBHblX ΘΓΘΗΤΟΒ ηβχιαθτοβ AnoKTMnoBbiii 3φΜρ HaTpueBoii cojim cy/ib0oflHTapHoii KucnoTbi, a nMemno noBepxHocTHo-aKTMBHbiii areHT "Aapo30Jib OTB" (npoMbiLUAeHHbiii npOAyiCT φΜρΜΝ "ΟΜβρΜΚΘΗ CnaHSMMA KOMnaHM"). B ΠΟΑΟδΗΗΧ K0Mn03MLļMflX MO)KHO MCnOflbSOBaTb ΤΘΙΟΚΘ OT ΠρΜΜβρΗΟ 60 % flO ΠρΜΜβρΗΟ 94 eec. % MHepTHoro τβθραογο pa36aBMTenjļ, HanpuMep μοητμορμπποημτθ, aTTanyjibrnTa, Mena, TanbKa, Kaonima, αμθτομμτοβομ 3ΘΜΠμ, μ3βθοτηηιο, CMJlMKaTOB ΜΠΜ MM ΠΟΑΟδΗΝΧ HOCMTeneii.
Φορμοβθηηνθ rpaHynbi, KOTopbie ββ/ιηιοτο?ι οοοδβΗΗΟ npMroflHbiMM AJlfl MCnOJlb30BaHMfl Ηθ ΠΟΜΒΘ ΜΠΜ B ΒΟΑΘ, MOI7T 6blTb nOJiyMeHbl B pe3ynbTaTe cMeujMBaHMf) b npMMepHO oflUHaKOBoii προπορμΜΜ, o6whho ot 3 Ao 20 MacTeti, npoM3BOAHbix apMnnuppoiia μ τβθραογο ποβθρχηοοτηο-aKTMBHoro areHTa, c ot npMMepHO 60 ao 94 MacTeii rMnca. Ilocne 3τογο CMecb φopMyιoτ b βμαθ He6onbUJMX HacTmļ-rpaHyn, μμθιοιαμχ pa3Mep 24/48 Meui μπμ 6onee. B HMCJIO ΠρΟΗΜΧ ΠΟΑΧΟΑ&ΙΑΜΧ nOBepXHOCHO-aKTMBHblX areHTOB, npnrOflHblX AJ1J1 K0Mn03MLļMM COmaCHO HaCTOimļeMy M306peTeHM(0, ΒΧΟΑΗΤ ΗΘ TOJlbKO aHMOHHbIM flMOKTMJlOBblM 3φΜρ ΗΒΤρΜΘΒΟΜ COflM CyJ^bφOHHTapHOM KMcnoTbi, ho TaioKe μ ηθμοηηβιθ 6/iOKcononMMepbi okmcm θτμπθηθ m okmcm ηρΟΠΜΠΘΗΘ. llOA06Hbie 6nOKCOnOJlMMepbl flBJIfltOTCfl npOMbllUneHHblMM npOAyKTaMM φΜρΜΝ "ΒΑΟΦ BMaHAOTT ΚορηορβΜΙΑΗ" ΠΟΑ φΜρΜΘΗΗωΜΜ ο6ο3Η34Θημαμμ "ΠηιοροΗΜΚ 10Ρ8, 17Ρ8, 25Ρ8, Φ38, Φ68, Φ77 μπμ Φ87"; ΟΗΜ ΒΒΠΑΙΟΤΟΗ ΟΟΟδθΗΗΟ θφφβΚΤΜΒΗΝΜΜ ΠρΜ ΠΟΓ^ΗΘΗΜΜ φορΜΟΒΘΗΗΒΙΧ rpaHyn. ΠΟΜΜΜΟ OnMCaHHblX BblLUe Κ0ΜΠ03ΜΙ4ΜΜ Β φορΜΘ ΠΟΠρΟΙϋΚΟΒ Μ KOHLļeHTpaTOB, mo>kho Mcnonb30BaTb τβιοκβ CbinyHMe μ pacTBopMMbie nopOLUKM, nOCKOJ1bKy ΟΗΜ CnOC06Hbl K AHCneprupOBaHMK) B BOfle. ΠρβΑΠΟΜΤΜΤenbHo noAo6Hbie ποροιυκΜ ajih pacTBopeHMB πρμμθηηιοτ b 10 LV 10895 30Hax, rfle npoM3BOflHTcq pacnbmeHMe βοαηνχ KOMno3HLļnii Ha nncTBe pacTeHMii, noAJie>Kamnx 3amnTe. llofloGHbie pacTBopbi AJia pacnbīneHHa mo>kho Mcno/ib30BaTb τβιοκβ Ha rpyHTe c npopaiiļHBaeMbiMH βοχοαθμμ, Ha nHLA@Bbix npoAy«Tax unh MecTax o6nTaHna HaceKOMbix η κηβίμΘΜ, KOTopbie noAne>KaT yHHHTO>KeHHK). B cnywae, Korfla κομπο3μαμμ οοθαμηθημμ cornacHO HacTO«iiļeMy Μ3θ6ρβΤΘΗΜΙΟ ΠΟΑΠΘΚΘΤ MCn0Jlb30BaHHK) COBM0CTHO C flpyrMMM neCTHLļMflaMH, K0Mn03HLļMH MOP/T 6blTb HCn0J1b30BaHbi B Btifle cMecen c ApyrMMH ΚΟΜΠΟΗΘΗΤΘΜΜ ΜΠΜ >ΚΘ MOryT BHOCMTbCfl nOCJieflOBaTeflbHO. AHanorHHHbiM o6pa30M, >KHflKne K0Mri03Hi4Hn apnnnnpponoe b KOM6nHai4MH c APyrnMn necTHLļMAaMM MoryT 6biTb nonyHeHbi ομθιιιθημθμ b θμκοοτηχ, min x<e Μοιγτ 6biTb ncnonb30BaHbi OTAeribHo h nocneAOBaTenbHO b BMAe >KHAKOCTeii ana pacnbīneHHa. KoMno3nnnn οοθαμηθημμ cornacHO HacTOflmeMy μ3ο6ρθτθητκ> β βμαθ κμακοοτθμ ņnn pacnbīneHna MoryT coAep>KaTb οτ npHMepHO 0,001 eec. % ao npuMepHo 0,1 eec. % θκτμβηογο ΚΟΜΠΟΗΘΗΤΘ. llpMBeAeHHbie ημ>κθ npuMepbi nnnK)CTpnpytoT HacToauļee H3o6peTeHMe. ΠρΜΜΘΡ 1 3-6ρ0Μ-2-(Π-Χ/10ρφθΗΜ/ΐ)-1-[(2,2,2-ΤρΜφΤ0ρ3Τ0Κ0Μ)ΜΘΤΜΠ]- 5-(τρΜφΤθρΜβΤΜΠ)ΠΜρρθΓ-3-Κ3ρ6θΗΜΤρΜΙ1
160 r (0,003 Mona) 3-6ροΜ-2-(π-χηορφβΗΜη)-5-(τρΜφτορΜβΤΜη)ΓΜρροη-3-Kap6oHHTpnna pacrreopaioT b cyxoM τeτpaΓHApoφypaHe μ AoāaenaioT κ AHcnepctiH β τeτparnApoφypaHe 1,25 οκβ^βθ/ιθητοβ rHAPHAa Kanna. PeaKiļnoHHyK) CMecb nepeMemneaioT β τθηθημθ 10 MHHyT, o6pa6aTbiBaioT χπορΜΘΤιιη(τρΜφτορΜβΤΜηοΒωΜ) ΘφΜροΜ (0,54 r, 0,0036 Monen), nepeMeiiineaioT β τθηθημθ npnMepHO 48 aacoB npn κομη3τηομ 11
TeMnepaType m 3aieM βηπμβ3Κ)Τ β 6onbiuoii o6beM eo^bi μ 3KCTparnpyioT ΘφΜροΜ. SKCTpaKT npoMbieaioT pacco/ioM, cyuuaT Hafl cyr^aTOM Mamnn m KOHi4eHTpnpyK)T b BaxyyMe, nonynafl οοτβτοκ, M3 κοτοροΓο nocne ΧρΟΜβΤΟΓρβφΜρΟΒβΗΜΒ Ha ΟΜΠΜΚΘΓΘΠΘ (CMeCb 1.1 ΧΠΟρΜΟΤΟΓΟ ΜΘΤΜΠβΗβ Μ re«caHa) nonyHatoT yKa3aHHoe b 3aronoBKe coeflUHeHne b BMfle TBepfloro npoflyKTa 6enoro LļBeTa (0,90 r, Bbixofl 68%); TeMnepaTypa π,πθβπθημβ 124,6-125,3 °C. B cooTBeTCTBMM c onncaHHbiM BbiLue cnocoāoM, ho ripu ncnonb30BaHnn cooTBeTCTByioiJ4ero 3aMeiiļeHHoro φβΗΜ/ιπιιρροη-3-Kap60HMTpM/ia MJ1M 3-ΗΜΤρθ-2-(38ΜΘ111ΘΗΗΟΓθ)φΘΗΜ/1ΠΜρρθ/13 m cooTBeTCTBy(oiiļero areHTa anmnwpoBamn nonyMaK>T nepeMucneHHbie ημ>κθ COeflMHeHMfl.
A L M R X Y T. n/i. °c CH2COOC2H5 H 3-CI 4-CI Cl Cl 118-120 CH2COOC6H5 H 3-CI 4-CI Cl 0 T1 CJ ļ ch2cooc6h5-p-ci H H 4-CF3 Br cf3 CH2OCOC(CH3)3 H 3-CI 4-CI Cl Cl CH20COCH3 H H 4-CF3 Cl Cl ch2cn H H 4-CI Br cf3 142-144 ch2cn H H 4-CF3 Cl Cl 137-139 ch2cn H H 4-Br Br 0 "Π CJ 110-113 12 LV 10895
A L M R X Y T. im. °C CH2OCOC(CH3)3 H 3-CI 4-CI H cf3 116-119 ch2ococ6h5 H H 4-CI Cl Πρμμθρ 2
OnpefleneHiie ΜΗΟΘκτΜμΜβΗοΡί m aKpMLļMflHOM βκτμβηοοτμ.
Bce McnbīTaHMfl προβοαητ c ncnonb30BaHneM τθχημμθοκμχ MaTepnanoB. Bce KOHiļeHTpaiļMH othocbtcb k aKTHBHOMy κοΜΠΟΗβΗτγ. Bce McnbīTaHMB npoBOflBT ripu TeMnepaType 27 °C.
Spodoptera eridania, πμημηκιί 3-m CTanm. K)>KHaa coBKa (noxoiiHbifl nePBb) ilucTba 0aconn riMMa atihhom 7-8 cm norpy>KaioT b cycneH3M»o ncnbiTyeMofi κομπο3μι1ΜΜ npn nepeMemuBaHMU b τβΜβΗΜβ 3 ceKyHfl, nocne nero cyiuaT. 3aieM nncTba noMei^atOT b MawKy Πβτρκ 100x10 mm, Ha aho κοτοροίί noMeuļeHa φΜΠΒτροΒ3ΠΒΗ3ίΐ 6yMara m 10 ryceHMLļ b 3-fi cranm pa3BMTMB. HamKy Πβτρκ Bbiflep>KHBaK)T b TeneHne 5 cyTOK, nocne Mēro onpeflejiflKDT CMepTHoeTb, yMeHbweHne KonusecTBa ctefleHHoro, min nio6bie οτκποηθημη ot HopManbHoti nnHbKH ryceHMi4bi.
Spodoptera eridania. OCTaTOMHoe B03aeficTBne nepe3 7 cvtok
PacTeHM«, nponiefliiine o6pa6oTKy b οοοτβθτοτβμμ c onMcaHHbiM Bbitue TecTOM, Bbiflep>KMBaK>T b Tennmļe ποα πθμπθμμ 6onbwoii mou1hoctm β τβΜβΗΜβ 7 cyTOK. yKa3aHHbie naMnbi yflBanBaioT 3φφβκτ «CHoro COJIHeMHOrO flHH Β ΜΙΟΗΘ Ha LUHpOTe LUTaTa HbK)-fl>KepCM H COOTBeTCTBy»OT ceeTOBOMy flHio β τβΜβΗΜβ 14 Maco β cyTKM. CnycTbfl 7 cyTOK co6npa»OT 13 o6pa3Lļbl JlMCTBbl M MCnblTblBafOT B ΟΟΟΤΒΘΤΟΤΒΜΜ C ΠρΜΒβ/1βΗΗΗΜΜ BblLUe ycnOBMflMM.
Aphis fabae. cMemaHHan CTanna pa3Bntm 6o6oBan τηη ΓοριυκΜ, coflep>KaLiļMe οαμηοηηνθ pacTeHMH HacTypLļnn (Tropaedum sp.) BbICOTOM ΠρΜΜθρΗΟ 5 CM, 3apa>Ka»OT ΠρΜΜβρΗΟ 100-200 TJIflMM 3a CyTKM nepefl npoeefleHneM McnbīTaHtin. Ka>KAbiii ropmoK o6pa6aTbiBaioT pacnbmeHneM ncnbiTyeMow κομπο3μι4μμ npn 2 οδοροτβχ co cKopocTbK) 4 o6/mmh HacaflKM c pacnbmmeneM Ns 154 "fleBunOncc". HaKOHeMHHK pacribinuTenn HaxoflHTcn Ha paccTOflHnn npMMepHo 15 cm ot pacTeHMn, a noTOK HanpaB/ifliOT τθκμμ o6pa30M, ητο6η oāecnenmb ποπηοθ noKpbune pacTeHnii m τηβίί. 06pa6oTaHHbie ropiUKM noMeu^atoT Ha 6enbie 3MannpoBaHHbie noflHocbi m Bbifl,ep>KHBaioT β τθμθημθ 2 cyTOK, nocne μθγο onpeflermioT cMepTHocTb τηβίί.
Tetranvchus urticae (P-pe3ncTeHTHbiii ιιιτβμμΙ. navKoo6pa3HbiH tcneiii
OiSktpaioT pacieHHH φβοοπη nwMa c rnaBHbiMH nticTbflMM AnMHOti 7-8 cm λ Bbipe3aiOT nmuHMe, ocTaBJiHfl 1 pacTeHMe β Γοριυκβ. He6o/ibuJOM «ycoK riMCTa H3 OCHOBHOM KOJ10HMM ΟΤρβ33Κ)Τ H Π0ΜΘ1118Κ)Τ Ha Ka>Kflblii J1MCTOK ncnbiTyeMoro pacTeHun. 3iy onepaLjuio ocymecTBn«K)T 3a 2 naca po nanana McnbīTaHUM, hto πο3Βοπ«θτ KneuļaM pacnpocTpaHMTbca no wcnbiTyeMOMy pacTeHmo h omojKMTb niiLļa. Pa3Mep 0Tpe3Ka nncTKa nofl6npaK)T TaKHM o6pa30M, HTočbi oh co/ļep>Kan npMMepHO 100 Kneuļeii. Bo speMn o6pa6oTKH οτρβ3οκ jiMCTa, ncnonb30BaHHbiii flrifl nepeHoca «nemeti, y,qann»OT m Bbi6pacbiBaioT. 3apa>KeHHbie KneiiļaMM pacTeHUp norpy>xaK>T Ha 3 cex b HcnbiTbiBaeMyio K0Mno3HLļHK> ripu nepeMeujMBaHMH, nocne nero noMemaioT Ha KpbiiuKy pna cyujKM. PacTeHnn Bbiflep>KMBaioT β τθμθημθ 2 cyroK, nocne nero onpeflennioT Hiīcno yHMMTO)KeHHbix B3pocnbix «nemeti c ncnonb3oeaHneM fln« οτοίί iļenu nepeoro nncTKa. Βτοροϋ nticTOK Bbiflep>KMBaK)T Ha pacTeHtiti β TeneHtie βιμβ 5 cyTOK, nocne nero onpeflenniOT ntīcno yHHHTO)KeHHbix nm; n/nnn BHOBb no«BHBiiJMxcn ημμΦ Kneuļa. 14 LV 10895
Diabrotie undecimpunctata havardi . 3-a CTauMfl pasBHTtia ?KVKa-6rioajKH flJIHHHOVCOH 1 mji TOHKOM3MenbMeHHoro TanbKa noMeiiļaioT b 30 mji cocyfl H3 cTeiaia c lumpokmm ropnoM m saBMHHUBaioLueMcn κρωιυκοΑ. Πμπθτκομ HaHOCflT Ha TanbK 1 mji cooTBecTByK)iiļeM cycneH3mi b aiļeTOHe τθκμμ o6pa30M, 4To6bi MMeTb 1,25 m 0,25 μγ θκτμβηογο κομποηθητθ Ha cocyfl. Cocyflbi Bbiflep>KHBaKDT nofl c/ia6biM ποτοκομ B03,qyxa flo ncnapeHM« aLļeTOHa. K BbicyLueHHOMy Ta/ibKy flo6aBfiflK)T 1 mji οθμηη npoca, κοτοροβ flon>KHo cny>KMTb b κθηθοτβθ nnuļn απη ηθοθκομβιχ, nocne μθγο b Ka»<flbifi cocyfl fločaBnsnoT 25 μπ yena>KHeHHOM noMBbi. Cocyfl 3aKpbiBa»OT κρωιυκοίί m ero coflep>KMMoe TiiļaTenbHO nepeMeiuHBaKiT Ha CMecmene "Βορτβκο". flocne 3τογο floOaBnaiOT no 10 jimhhhok 3-fi cTaflMH pa3Bmnn >KyKa-6/ioiUKH fl/1HHHOyCOM B KaJK/ļblM COCyfl H ΗβΓθρΜβΤΜΗΗΟ 3aKpblBaiOT MX KpblLUKOM flJlH ΟΒΟδΟΑΗΟΓΟ o6MeHa B03flyX0M flJlfl >KM3HefleflTeJlbH0CTVt JIMHHHOK. 06pa6oTKy προβοαητ 3a 6 cyTOK ao onpefleneHHH CMepTHocTH HaceKOMbix. HeHaiiAeHbie jimhmhkm paccMaTpnBa»0TCfi κθκ yHMHT0>KeHHbie, nocKOJibKy ohm δΗοτρο pa3naraK)TCH h ηθ MoryT 6biTb o6Hapy>KeHbi. KoHLļeHTpaiļMM, ncnonb3yewbie npn McnbīTaHMM, cootbbtCTByιοτ npHMepHO 50 h 10 Kr/ra aKTMBHOrO Κ0ΜΠ0ΗβΗΤ3. OLļeHOHHan LUKa/ia: 0 = 0TcyTCTBne οφφβκτθ; 5 = 56-65 % CMepTHocTH; 1 = 10-25 % CMepTHocTH; 6 = 66-75 % CMepTHocTH; 2 = 26-35 % CMepTHocTH; 7 = 76-85 % CMepTHocTH; 3 = 36-45 % CMepTHocTH; 8 = 86-99 % CMepTHocTH; 4 = 46-55 % CMepTHocTH; 9 = 100 % ομθρτηοοτμ; R = yMeHbLueHne ποτρβδ/ιβΗΜΑ nnmw. noriyMeHHbie b pe3ynbTaTe ncno/ib30BaHMn onMcaHHOM Bbiiue oLļeHOMHOM iiiKanbi flaHHbie πρμβθαθην b Ta6n. I. 15
OnpefleneHne HHceKTMUnnHoči n ai<apnumiHOH aKTUBHOCTH , 2 2 ». i * 1 55 O σ> o o CO 00 o 05 o s. o co o a- ο 1 4 111 * ģ o n o σ> σ> o o o 05 o 05 o 05 • o o o K π X * 2 co co o O X O o h- 05 σ> σ> 05 05 o> 05 05 05 05 05 05 05 (D 05 ct s o o 05 05 05 05 05 05 05 05 05 05 05 05 05 05 05 § ά 2 ī σ> 05 05 cn 05 05 05 05 05 05 05 05 05 05 05 K ~ t6 ^ H ffl 5 č -I I Ο Ο o O O o O O o o O o o o ω s X <D X X d Φ o o c x α H s X o H 0) a re q & α s c* s r 0) t o c X x ct co 6 X te x a α o c X x «5 co CN Η re Η 4> a te q s α H χ X <8 α 2 CO c 8 α x c c* x c o Ķ č ά e -Θ- x CL Ķ a 8 ^B CŅ c S 03 2 X u X ? f- ά o c X s 5 c s α κ s X ο Η a a te 1 ά & α X q* s q 0 k c 1 α o H -Θ- X α K 8 b" ub 6 X (0 s a <£> ά o 5 š co 04 c x α H x X o ►— rr re c & Q. x c c s H 0) 2 O. o H Θ- x α CN ό X te x a X c* x X o Q X c un 2 o α ΙΟ CO CL s £ >x Λ ffl O c X H- 0> 2 re H o c o s X X re X o > o X >. c x a 2 x α H c x q o α α s c Έ x X 4) £ 0 C X x ct O- co ub 6 X re x a α ο 5 ē 1 CO CN C x α I- x r o K 0) a re c & α x Έ* x H 47 2 CL o H Θ- s α »- CŅI X X 47 •θ α o c X X ct rr co T o X re X a uļ> 2 o α co 2 >- o c o X X >x o X o >s >% c X η 47 2 X α ν α X S c X α h X X 5 α re X CŅ C O α α X £L c X k 47 2 α o H -Θ- X α uļ> c X K 47 2 X o X ? c* X X 47 t Ķ rf CO co 2 o α ΙΟ TJ· C X α V- X X o H 47 a re c a α X c X re X rr X 'c X X 47 t O c X £ tņ o. o q X X 9 CO CN 2 H o c o X X >x o X o >N o X >v c X K 47 2 X α ί α X f c X α H X X 5 α ? CO c o α α X c 'c X K 47 2 α o >- •Θ· X α uS ά X H 47 2 X ? *q X X 47 t O 5 C CN 2 o α UD θ' 2 H- 0 c o X X >x o X o >5 o X >> c X 07 2 X α »- α X f c X α 1- X X & α re X CN ά a α X 'c X K 47 2 X o, X X 47 t 0 5 C ub 1 2 a vo X ? co* α X t IX 2 a 0 c X H 4) 2 re* H 0 c o X X K re X o >. υ X >s c X h» D 2 X α H c X c a α X X c 0 H C ά o h* Θ- X α 1- B B ^B uS 0 X re X a α 8 X X ct co CN α X t X 1 8 X h» a 2 re* 5 c υ X X X re X o >> D X >N X X h a 2 X α Έ X c a α X c q X K a 2 α 0 H Θ- X α H n a X X co c* X X a t 0 c X X c£ rr <o CN q X α h· 5 X 0 a a re ά a α X c c* X H· a 2 α 0 h* 6* X α H co ά Σ re X a X 1 2 6 uo c co 2 o α UO co ς X α H X X a α 2 co č o α α X C o X re X a X *c X X a θ α 0 s c 1 CN ά o c X lO 2 o α UD co α X £ )S 2 m o c X a 2 re* H O c o X X re X υ >s υ X >% C s a 2 X α H C X ά o α α X c cT X X a θ α o 5 X ? zL CŅ 6 X re X a t α 0 5 1 ņ 2 O α uD co LV 10895 ΠΡΜΜΘΡ3
OnpefleneHne μηοθκτμαμαηομ θκτμβηοοτμ Heliotis virescens, 3-a dāņus pa3Bmnn. nncTOBOpoTKa-noHKoeA Ta6aHHan
CeMeHa xjiormaTHW<a norpy>KaK)T b McnbiTbiBaeMyio κομπο3μι4μκ> m cyujaT Ha κρωιυκθ. l"locne cyiPKM Ka>Kfloe M3 ceMSH pa3AensioT Ha ηθτβθρτμ m 10 sacTeii ποΜβιμβιοτ MHAMBMflyanbHO b nnacTMaccoBbie beflMLļMHCKMe eMKOCTM no 30 ma, coflepjKaiiļne οτρβ3θκ αγιμηομ 5-7 mm Bna>KHoro 3y6Horo TaMnoHa. B Ka>KAyto eMKocTb noMeiiļaioT no oahoh ryceHMLļe b 3-Pi craam pa3BHTnn m 3aKpbiBaioT eMKocTb KapTOHHOM KpbiujKofi. 06pa6oTaHHbie o6pa3Lļbi Bbiflep>KMBaioT b τθμθημθ 3 cyTOK, nocne nero οπρβΑβηηιοτ CMepTHOCTb n OLļeHUBaKDT yMeHbiueHMe ποτρβδηβΗΜΒ nmaHMS.
Empoasca abrupta. Bspocnbīe oco6n KapTocbenbHofl Ko6binKH
JlMCTbs φβοοηΜ nuMa AnHHoii npMMepHO 5 cm norpy>KaiOT B ncnbiTbiBaeMyK) κομπο3μι1μιο Ha 3 ceK πρΜ πθρθμθιρμβθημμ, nocne ηθγο noMeuļatoT cyuiMTbcs Ha κρωιυκβ. JImct noMeujaioT b HaiUKy Πβτριι 100x10 mm, Ha αηθ κοτοροϊί HaxoAHTcn yena>KHeHHan cļ)MnbTpoBanbHan 6yMara. B Kax<Ayio HauiKy Πβτρκ ββοαατ npMMepHo 10 B3pocAbix οοοδβίί KapTocķenbHOM κοδωηκΜ m BbiAep>KMBaK)T o6pa6oiaHHbie o6pa3iļbi b τθμθημθ 3 cyTOK, nocne μθγο οπρβΑβηηιοτ CMepTHOCTb.
Blatella aermanica, HcnbuaHHa npHMaHKH, B3POcnbie ocq6h caMiga pbDKero TapaKaHa 0,1 %-yto npnMaHKy nonyHatoT b pe3ynbTaTe Ao6aBneHnn M3 πμπθτκμ 1 μα pacTBopa, coAep)KaLAero 1000 m.a. ncnbiTyeMoro οοθαμηθημη b aiļeTOHe, Ha 1 r πιρθημμηογο xne6a, noMemeHHoro b 30-ma eMKocTb c LUHpoKHM ropnoM. npiiMaHKy cymaT nocpeACTBOM nponycKaHns nerKoro ποτοκθ B03Ayxa b eMKocTb. 3aTeM npnMaHKy noMeuļaioT b wnpoKoropnbiH cocyA MacoHa Ha 1 nnmy m Ao6aBnstoT TyAa >κβ 10 B3pocnbix caMLļOB pbDKero TapaKaHa. CocyA πρμκρμβθιοτ οθτηθτομ κρυιυκοίί, a ceepxy Θτοίί KpbiiiiKH noMeiAajoT He6onbwoii KycoMeK BaTbi, nponuTaHHbiii 10 %-HbiM pacTBopoM MeAa. CMepTHOCTb onpenenstoT cnycTbs 3 cyTOK. 17
Spodoptera eridania. cHcteMHoe nccnenoBaHHe. phhmhkm 3-m cranm. >o>KHap COBKa (ΠΟΧΟΡΗΝΜ HePBb)
Coe/ļMHeHne nopypaK)T b βμαθ 3Mypbcnn, coflep^aii^eii 0,1 r ncnbiTyeMoro οοθαμηθημρ, 0,2 r 3MypbraTopa "3MyPb4>op EL-620", 10 μπ aiļeTOHa m 90 μπ βοαη, nopyneHHyio 3MypbCMio pa36aBPPioT 10-KpaTHbiM M36biTKOM BOflbi, nopynap 3MyPbCMK> McnbiTyeMoro οοθαμηθηιίρ KOHLļeHTpaLļnefi 100 M.fl. ΠρΜ ηθο6χοαμμοοτμ nonyMaiOT fla/ibHeiiLUMe 10-KpaTHO pa36aBiieHHbie pacTBopbi b BOfle. cpaconb ρμμθ, rnaBHbie PMCTbP κοτοροΜ ΜΜβιοτ fljiMHy 7-8 cm, cpe3aK)T Ha ypoBHe no MeHbiueM Mepe 3 cm naņ, ποηβομ c iļenbīo M36e>KaTb 3arpp3HeHMP noHBeHHbiMM OaicrepMPMM, κοτορωβ MoryT Bbi3BaTb 3amnBaHne οτββρρ b xofle ηροθβΑβΗΜΡ McnbuaHMP. Cpe3aHHbie οτθ6ρμ noMeu^atOT b McnbīTbieaeMbie 3MypbCMM m npnxBaTbiBa(OT xa>KAbiM M3 cTe6xieu kjiohkom BaTbi απρ yflep>KaHMP ero Ha paccTOPHHM ot flHa cocy#a h ap* orpaHMHeHMp McnapeHMP h ypeiyHMBaHMP coeAMHeHHP. McnbīTaHHe ocyiiļecTBPPioT b τθμθημθ 3 cyTOK npM 27 °C, mto πο3βογιρθτ coeAMHeHMK) npoHMKHyTb b pacTeHMe. BcneA 3a 3thm c pacTeHMP cpe3atoT oamh pmctok m noMeuļaiOT ero b HaujKy ΠβτρΜ 100x10 mm, C0Aep>KaLAyKD 10 ocočeii kmkhom cobkh. CMepTHocTb m coKpauļeHMe noTpeāneHHP πμτθημρ onpepeppioT cnycTbP 3 m 5 cyTOK.
Empoasca abrupta, B3Docnbie oco6m KaDTocbePbHOM KoābiPKM. cncTeMHoe HccneaoBaHue
CoeAHHeHMe nopynaiOT b βμαθ 3MyPbCMM, copepaoLneM 0,1 r ncnbiTyeMoro οοθαμηθημρ, 0,2 r 3MynbraTopa "3MyPb(f)op EL-620", 10 mp aLļeTOHa h 90 mp BOAbi, riopyHeHHyio 3Mypbcmo pa36aeppK)T 10-KpaTHbiM H36blTKOM BOAbl, nOPyHaP 3MyPbCHtO MCnblTyeMOrO ΟΟβΑΜΗΘΗΜΡ KOHLļeHTpaAMePi 100 m.a. ΠρΜ Heo6xoAMM0CTM nopyHaiOT Aa^bHePiujMe 10-KpaTHO pa36aBPeHHbie pacTBopbi b eope. OacoPb ρμμθ, maBHbie PMCTbp κοτοροΜ ΜΜβιοτ AnnHy 7-8 cm, cpe3aioT Ha ypoBHe no MeHbmeM Mepe 3 cm HaA πομβομ c pePbK) M36e>xaTb 3arpp3HeHMP ποηβθηηημμ 6aicrepMBMM, KOTOpbie MOryT Bbl3BaTb 33ΓΗΜΒ3ΗΜΘ CTe6PP B ΧΟΑΘ ΠρΟΒβΑβΗΜΡ MCnblTaHMP. Cpe3aHHbie οτθ6ρμ noMematoT b McnbīTbieaeMbie 3Mynbcnn m npMXBaTbiBaK)T κθ>καημ M3 cTe6peii kpohkom BaTbi a^ yAep>xaHMP ero Ha 18 LV 10895 paccTOJiHm ot p,na cocy/ļa m fl/in orpaHHHeHMfl McnapeHMfl m yneTyHHBaHMfl coeflMHeHUfl. 1/lcnbiTaHne ocyiiļecTBnflK)T b τθηθημθ 3 cyTOK npn 27 °C, mto πο3βοπηθτ coeflMHeHMto npoHMKHyTb b pacTeHne. Bcnefl 3a stum c pacTeHnn cpe3aK)T oflMH timctok m noMeiiļaioT ero b MaujKy rieipn 100x10 mm, coflep>Kaiiļyio 10 oco6etf ιορτοφβπΒΗοΡί κοβωηκΜ. CMepTHOCTb onpe/ļenafOT cnycTbii 3 cyTOK. flrm ομβΗκι/ι ncnonb3yioT 3MnnpnHecKyK) LUKany, onncaHHyio b npuMepe 2. nojiyHeHHbie flaHHbie npuBefleHbi b Taānmļe II. flpuMep 4
OnpefleneHne HeMaTmļMflHoPi aKTUBHOCTM coeflMHeHuPi comacHo HacTOfliiļeMy μ3ο6ρθτθημκ>
KynbTypbi: Mcnonb3ytoT KynbTypy C. elegans (BpucTonbCKuii ιιπέμμ no fl>K. J1bioMcy), Ha E. coli, BbipauļkiBaroT Ha nnacTMHKax arap-arapa NG npH 20 °C. HoBbie KyjibTypbi nonyHaioT Ka>KAyio ηθαθπιο.
HeMaTOflbi ada npoBefleHmi ncnbīTaHMM οτμνβθιοτ ot KynbTyp B03pacTOM 4-5 cyTOK c ncnonb30BaHneM οβθ>κθγο pacTBopa FARS. JIummhkh BHOBb npoMbiBajoT FARS, coflep>KaiAHM reHTaMMLļHH, c Ljenbīo yMeHbiueHMfi 5aKTepnanbHoro 3arpfl3HeHMfl, m i4eHTpi^yrnpyioT απλ οταθπθημα jihmuhok ot npoMbiBHoro pacTBopa. YKa3aHHyKD npoi4eflypy ποΒτορηιοτ 3 pa3a. ripoMbiTbie PMHMHKn Ao6aBnsiioT κ cpefle, noAqep>KUBaiOLnePi C. briggsae ( M3 GIBCOa), κ κοτοροΡί floSaBJiatoT reHTaMULļHH (600 θα./μπ) μ μμκοοτθτμη (0,5 μγ/μπ). riocne θτογο γοτοβητ o6pa3L4bi ajih μοπντθημμ H3 CMecu Tpex coeflMHeHnii, M36erasq ncnorib30BaHMfl Apyrnx 6onee coBepiueHHbix nporpaMM ncnbīTaHuii c iļenbK) yMeHbLueHMfl 3aTpaT paāonePi cnribi m coeflMHeHMii.
CoeflMHeHMfl pacTBopsiioT b aLļeTOHe μ aoboaat pacTBop ao onpefle^eHHoro o6teMa nocpeflCTBOM ,qo6aBJieHMfl paBHbix MacTePi BOflbi. Κοηθηηθη KOHiļeHTpaLļnn Ka>Kfloro M3 ncnbiTyeMbix οοθαμηθημΡι β ομθομ cooTBeTCTByeT 150 M.fl. McnbiTyeMbiPi MaTepkian nepeHocHT nocpeflCTBOM ΜΜΚρΟΠΜΠΘΤΚΜ (25 MKJl) B OflMHOHHyK) ΗΗθΡίΐψ 96-«ΗΘΘΜΗθΡί CTepMJIbHOPĪ nnacTMHKM flrm nccneflOBaHmi τκθηθβνχ KynbTyp (COSTAR) m flaioT BO3MO>KH0CTb pj\n ncnapeHWļ pacTBopuTejiii. "06pa6oTaHHbie" τθκμμ 19
Onpenenemie ΜΗοβκτκιικπΗΟΗ h aKapnuwiHOH aKTUBHOCTM X 2 (0 Ο. (ϋ 2 x o S i 1 Ϊ O) o O) ¢3¾ O) 00 σ> σ> ο 05 05 o ο co X re o · Z re o «i s * o s α ^ C o 05 05 (O 00 in 05 o N- ο ΙΛ <o 1 1 ο o X z 0) h* O s O 2 « 1 i * l O O 1^ o o O o o ο ο o 1 ο 05 X _ Ct m re ^ 2 * 5 5 ω Λ 2 8 8 o O O o o o o o o ο ο co o ο ο ŠS Q_ <0 re i o <0 H *0 o re χ ιέ: CX 2 1 05 05 05 05 05 05 05 05 ο 1 05 05 05 05 8 3 2 s 0¾ 05 05 05 05 05 05 05 05 00 05 05 05 05 05 Q χ «=ī i * |0 © o o ^ ·»- o i 05 05 O CO 05 o 05 05 Ο 05 S- ο 05 Φ s I 03 X s Ct Φ o O X x Cl 1- s X 0 h- 3* re x a α 1 o 5 X Ct 4 00 o X re x 3“ t O. o 5 ci CO Osi H re H Φ 3* re X x O. H x X a o. re co < 1 α x c c* X X o Ķ c o. 0 μ- -Θ- X α i- 1 0 6 ^a CM X X re Z X 3 ? o 5 X 3 Tf" 3 X O. H X X O H re re t— x a α X 3 X x o H • C ά o μ- 6- X α μ ι 3 a ^a ιΛ o X re X 3* ώ CL o 5 ? CO cm" x X α μ- X X 0 H re 3 re 1 x a CL X χ X μ- Ο) Z α o H θ' X α H CNI 6 X re X 3 X *3 X X * CL· 0 5 c uS Σ a \o 1 <r> α X t »x 3 m 8 X h* re z re K O x o X X X re X o >. 2 >y x X μ» re Z X α H cT X x o α Cl X c X* X X re θ α o X X X Ct rr ώ uļ> ό X re X 3 α o 5 ā CO CM* X; X α t- X X o re 3 re 3 O α α X x* X re s α 0 h -Θ- X α CM 1 o 5 Ķ ΤΓ 00* o X re X 3* uļ> 2 o α «p CO 2 H o c; o X X >x 0 X u >» >s 3 X re z X α μ α X f c X α μ- 1 2 CM X O α α X c c“ X h re z α o H € X α t- uS c X re z X υ X 9 c* X X re t o c X X Ct CO* 00 z a VO C X α K X X o H re 3 re c o α α X c X re X 3 X cT X X re -θ α o c X uS ά o c X X Ct CO cm" 2 h> o c o X X X o X o >. υ X >. C X K re z X α μ α X θ- Λ c X α μ- X X a α re X CO c ο α α X C* X Η re ζ α ο κ -θ- X α >- uS ά X κ re S X υ X 9 C* X X f α ο C X C CM Ζ a ι£) 4 2 μ- ο C ο X X >χ ο X ο >> ο X >Ν C X μ- re ζ X α ί α X S C X α μ- X X a α 2 1 CM ά ο α α X C c' X η re ζ X 3 ο 0 5 uS Ζ a 10 X ct 4 co’ α X $ >χ 2 ο ο C S Η re Ζ re μ- Ο C ο i X re X υ >Ν >s C X μ re ζ X α μ- C X C a α X C ”c X C Ο μ· C CL Ο μ- -θ- X α Η a a uS 0 X re X 3 Τ α X ct CO CM α X t >x 8 X μ- 0) z re ί- 0 c u X X X re X o >N >. X X H re Z X α K X X T- X a α X c X X H re z α 0 1--Θ- X α uS a H X X co 1 0 X X X Ct co* i X X α H X X o μ· re 3 re τ— c a α X j: X* X H re Z α 0 μ- θ* X α μ- CO ά X re X 3 χ 'χ X X 4 ζ & 0 C C0 ζ & 10 CO X X α I- X X a α 2 CO X ο α α X C ο X re X 3 X X X X re t 8 X έ CM ά ο 5 uS Ζ a \ο CO α X $ >χ 2 S ο X X Η re Ζ re* Ι Ο X υ 1 X re X υ >Ν 2 >* X X μ* re Ζ X α I- X X X a α X X* X X re t Ķ ττ co CM O X re X 3 α o X X uS z a \D co
ο CM LV 10895 cnocočoM nnacTMHKM πμ6ο Mcnonb3ytoT ηθμθαπθηηο, πμ6ο xpaHsu b xonoflnnbHMKe 6e3 κ8Κμχ-πμ6ο OTpnLļaTenbHbtx bosabmctbmm Ha οοθαμηθημη cornacHO HacTomiļeMy Μ3θ6ρβτβΗΜΐο.
Cee)KenpMroTOB/ieHHyK) KyjibTypy C. elegans b KynbTypHoii cpefle, noAqep>KMBaK)inefi C. briggsae, nepeHOCHT nocpeflCTBOM μμκροπμπθτκμ (50 ΜΚΠ) B KaXCAyiO M3 o6pa6oTaHHblX ΠΜΘΘΚ M HeCKOHbKO KOHTpOJlbHblX ΠΜΘΘΚ Ha
KajKfloii M3 njiacTMH. Π,πθοτμηκμ c KynbTypaMn Bbiflep>KHBaiOT npM 20 °C.
Ha6ntOfleHMfl βφφΘΚΤΜΒΗΟΟΓΜ npOBOflflT ΠΟΑ MHKpOCKOnOM CnyCTfl 4, 24 m 48 HacoB nocne o6pa6oTm HenocpeACTBeHHO nepeA ocmotpom nnacTMHKH ee octopo>kho nociyKMBaioT απ* CTMMynnLļMM αβμ>κθημπ πμμμηοκ. AlCTMBHOCTb OLļeHMBaKJT Cy6'beKTMBHO, HO nOJiyKOJlMHeCTBeHHO, OCHOBbIBaflCb Ha θφφβΚΤΘ epeACTB, B03AeMCTBy»0 UļMX Ha nOABHKHOCTb ΠΜΜΜΗΟΚ H B3pOC/lblX ΗβΜ3ΤΟΑ· ΠρΜ 3T0M MCnOAb3yiOTCfl ΟΊβΑγίΟΙΙΙΜΘ ΟμβΗΚΜ: 8 = OTcyTCTBne ποαβμχηοοτμ, 7 = 3aMeTHoe yMeHbineHMe ποαβμ>κηοοτμ y npHMepHO 95 % ΠΜΜΜΗΟΚ, 6 = yMeHbUieHHaa nOABM>KHOCTb, 5 = HeCKOHbKO yMeHbiueHHan noABM>KHOCTb, 0 = HopManbHaa noABM^HocTb, OAMHaKoeaa c KOHTponbHbiMM o6pa3LļaMM. ΠβΓκο MoryT 6biTb onpeAeneHbi m APyrne φβκτορω yKa3biBajoiAMe Ha aKTMBHocTb οοθαμηθημμ, τθκμθ ksk CMepTHoeTb, npeACMepTHafl κομθ, cyAopo>KHbie αβμ>κθημπ, M3BMBaHMe, napanMM, HeoābiMHoe noAeprMBaHMe, yMeHbiueHMe nonynyiLļMM πμμμηοκ 3a 48 Macoe m ΠρΟΜΜΘ Μ3ΜΘΗΘΗΜΗ ΠΟ ΟρθΒΗβΗΜΙΟ C HOpMaHbHblM ΠΟΒΘΑΘΗΜΘΜ. Μθτοαμκθ προΒβΑβΗΜΗ μοοπθαοβθημμ c Caenorhabolitis elegans. fleHb 0: HHOKynMpoBaHMe MaiueK ΠθτρΜ c arap-arapoM 30-50 C. elegans, MHKy6MpoBaHMe npM 20 °C. fleHb 4: BbipauļHBaHMe hobom nonynnu,MM C. elegans, npoMbiBKa 3ητμ6μοτμκ3μμ, nepeeoA b cpeAy, noAAep>KMBaiotJnyio C. briggsae, Ao6aeneHMe C. elegans (25-100μκπ) b Mo6pa6oTaHHbie"* πμθμκμ, HaānroABHMe 3a aKTMBHocTbio cnycTH 4 Mača nocne norpy>KeHMH. fleHb 5: HaGntoABHMe 3a aKTMBHOCTbio. fleHb 6: Ha6nKDABHMe 3a aKTMBHOCTbio. rionyMeHHbie b pe3ynbiaie yKa3aHHbix McnbuaHMM ABHHbie ΠρΜΒβΑβΗΝ ΗΜ>ΚΘ B ΤθβΠ. III. 21
Ta6nnua III
ΟπρΘ/1ΘΠΘΗΜΘ HeMaTMLļMflHOM aKTMBHOCTM
[2,3-flnxnop-4-LiMaHO-5-(3,4-flMx/iop0eHMn)nMppon-1-nnlTpMMeTviryKcycHafl mtcnoTa, μβτμποβμμ 3φι*ρ 0 4,5-/1Μχηορ-1-οκαΐΜθτνιπ-2-(α,α,α-τρΜφτορ-π-τοπΜη)πΜρροπ-3-Κ8ρ6θΗΜτρΜΠ, aiļeTaT a 4-6ρθΜ-2-(η-ΧΠθρφθΗΜΠ)-1-ΟΚΟΜΜΘΤΜΠ-5-(τρΜφΤθρΜΘΤΜΠ)ΠΜρροη-3-Κ3ρ6θΗΜΤρΜη, 3φΜρ TpMMeTM/iyKcycHoS kmcjiotu 0 4-6ρθΜ-3-(3(4-/3ΜΧηθρφθΗΜΠ)-1-ΟΚΟΜΜΘΤΜΠ-5-(ΤρΜφΤθρΜΘΤΜΠ)ΠΜρρθΠ-2-Κ3ρ6θΗΜΤρΜΠ, 3φ»ρ TpMMeTMPyKCyCHOM KMCJlOTbl 0 3,4-/1Μ6ρθΜ-5-(η-ΧηθρφθΗΗη)-1 -(OKCMMeTMTl)nMppO/l-2-Kap6oHMTpMfl, 3φΜρ TpMMSTMjlyKCyCHOM KMCnOTbl 0 (2,3-ΑΜχηορ-4-ΜΜ3Ηθ-6-(α(α,α-τρΜφτορ-π-τοπΜη)πΜρροη-1 -nn]TpMMeTwnyi<cycHafl KMcnoTa. μθτμποβμμ 3φΜρ 0 3-6ροΜ-5- 4ΜθΗθ-4-(3,4-ΑΜχηορφβΗΜη)-2-(τρΜφτορΜθτνιπ)ΠΜρροη-1- apeTOHMTpun 0 2,3-ΑΜΧπορ-6-ί|Μ8Ηο-5·(α,α,α-τρΗφτορ-η·το/ΐΜπ)πΜρρο/ι-1 - βμβτοΗΗτρΜίι a 3-6ρθΜ-5-(Π-ΧηθρφθΗΜΠ)-4-ί(Μ3ΗΟ-2-(τρΜφΤθρΜΘΤνΐη)ΠΜρρθΠ-1 - βΜΘΤΟΗΜΤρΜΠ a 2,3-ΑΜΧΠθρ-4-Ι1ΜΒΗΟ-(3,4-ΛΜΧηθρφθΗΜ/ΐ)ΠΜρρθΠ-1-34βΤΟΗΙ«ΤρΜη 0 [3-6ροΜ-5-χπορ-4-ΐ1ΐιβΗ0-2-(3,4-ΑΗχπορφθΗΜΠ)ΠΗρροπ-1 -Mn|rpMMeTMnyKcycHafl KMcnoTa, μθτμποβμμ 3φΜρ 0 3-6ροΜ-5-χηορ-2-(π-χπορφθΗΜη)-4-ΜΜβΗοΠΜρροπ-3- κβρδΟΗΜτρκη 0 3-6ρθΜ-5-(η-6ρθΜφθΗΜΠ)-4-4Μ3ΗΟ-2-(ΤρΜφΤθρΜβΤΜΠ)ΠΜρρθΠ-1 - aLļeTOHHTpMJl a 2,3-/1Μ)ίΠ0ρ-5-(Π-ΧΠ0ρφθΗΜΠ)-4-Ι(Μ3ΗηΜρρ0Π-1-3Ι4βΤΟΗΜΤρΜΠ 0 [2-(3,4-/1Μχρορφ3ΗΜπ)-3-ΗΜτρθ'5-(τρΜφτορΜΒΤΜΠ )nnppon-1 -nnļTpMMeTV(nyKcyoHafl κκοηοτβ, μθτμποβμμ 3φΗρ (-) Ακτμβηοοτβ no OTHOLuem/iK) κ C. elegans: 0 - HeaKTHBHo
a - aKTUBHO (-)- ΗΘ MCnblTblBanOCb * 06pa6oTaHHbie nMeiiKu Moryr 6biTb KaK cBejKenpuroTOBneHHbiMM, TaK m npuroTOBneHHbiMM paHea m xpaHHMbiMH b χο/ίοαμπβημκθ. 22 LV 10895 <t>OpMyna Μ3θβρβΤβΗΜΘ 1. Coe/jMHeHMfl, OTBeHafouļMe o6uļefi φορΜγπθ:
x Y b κοτοροϋ: X npeflCTaBnfleT co6om boaopoa, φτορ, χηορ, 6poM, moa μπμ CF3; Y npeflCTaB/ifleT co6om Boflopofl, φτορ, χ/ιορ, 6poM, moa, CF3 MnM CN; W npeACTaBiifleT co6om CN MnM NO2; A npeACTaBnfleT co6om anmn, coAeparamMM ot 1 ao 4 θτομοβ yrnepoAa, 3aMemeHHbiii 4 θτομθμμ ranoreHa, oahom LļMaHorpynnoM, oahom anKOKcnrpynnoft, coAep>Kamefi ot 1 ao 4 θτομοβ yrnepoAa, 3aMeiAeHHoii 1-3 aTOMaMU ranoreHa MnM AayMH an«OKCMrpynnaMM, bo3mo>kho AononHMTenbHO 3aMemeHHbiMn 1-3 aTOMaMU ranoreHa, oahom Kap6anK0KCMrpynnoM, C0Aep>KaiAeM ot 1 ao 4 θτομοβ yrnepoAa, oahom anKMnKap6oHMnoKCMrpynnoū, coAepjKauļeM ot 1 ao 6 θτομοβ yrnepoAa, oahom anKeHMnKap6oHMnoKCMrpynnoM, coAep^ameM ot 2 ao 6 θτομοβ yrnepoAa, oahom 6eH3onKap6oHMnoKCMrpynnoM, MnM χηορ-, Α^χηορ-, MnM ΜβτΜη33Μβϋ1βΗΗ0Μ 6eH3onKap6oHMnoKCMrpynnoM; L πρβΑοτθβηηβτ co6om boaopoa. φτορ, χηορ, MnM 6pom;
Μ m R npeACTaenfleT co6om Ka>KAbiM ηθ3Θβμομμο Apyr ot Apyra boaopoa, anKMnbHyio rpynny, coflep>KaLnyK) ot 1 ao 3 θτομοβ yrnepoAa, anKOKCMnbHyio rpynny, coAep>Kaiiļyto ot 1 ao 3 θτομοβ yrnepoAa, anKMnTMorpynny, coAepx<aiiļyto ot 1 ao 3 θτομοβ yrnepoAa, anκ^1ncynbφMHMnbHy^o rpynny, C0Aep>KaiAyio ot 1 flo 3 θτομοβ yrnepoAa, anκMncynbφoHMnbHy^o rpynny, coAep>KaLAyKD ot 1 ao 3 θτομοβ yrnepoAa, i4MaHorpynny, φτορ, χηορ, 6poM, MOA· HMTporpynny, rpynny CF3, R1CF2Z, R2CO wm NR3R4 , μ κογαθ Μ m R 23
HaXOflflTCfl B CM6)KHblX ΠΟΑΟ>ΚΘΗΜΑΧ Μ ΒΜΘΟΤΘ C 3ΤΟΜ3ΜΜ ymepOfla, C KOTOpbIMM OHM COeflMHeHbl, MOryT 06pa30BblBaTb KOAbLļO, B κοτοροΜ MR npeflCTaBJifliOT οοδοίί cTpyKTypy:
-OCFfeO-, -OCF2O- MAM Z npeflCTaBnfleT co6oii S(0)n mam O; R1 npeflCTaBfiReT οοδοίί eoflopofl, φτορ, CHF2 ,CHFCI, CF3; R2 npeflCTaB/ifleT οοδοίί anKM/ibHyio rpynny, coflepxamyio ot 1 ao 3 aTOMOB ymepoAa, a/iK0KcnjibHyK) rpynny, coAep>Kamyto ot 1 ao 3 θτομοβ ymepoAa, mam NR3R4; R3 npeACTaBnfleT οοδοίί a/iKi4/ibHyio rpynny, coAep>KaiAyio ot 1 ao 3 aTOMOB ymepoAa; R4 npeACTaBiifleT οοδοίί aTOM BOAopoAa, aAKMAbHyio rpynny, coAep>Kamyfo ot 1 ao 3 aTOMOB yrnepoAa, mam R5CO;
Rs npeACTaBAneT οοδοίί θτομ BOAopoAa, aAKMAbHy»o rpynny, coAep>KaiiļyK) ot 1 ao 3 aTOMOB ymepoAa, m η πρβΑοτθΒΑΑβτ οοδοίί LļeAoe hmcao, paBHoe 0, 1 mam 2; ripu tom ycAOBnn, mto KorAa X μ Υ πρΘΑοτβΒΑΑίοτ οοδοίί BOAopoA, a A πρβΑοτβΒΑΗΘτ οοδοίί aAKMAbHyK3 rpynny, coAep>KamyK5 ot 1 ao 4 btomob yrAepoAa, 3aMeiiļeHHyto oahom i4naHorpynnoM, to 3aMecTMTeAb
L
R / ΑΟΑ>ΚΘΗ 6blTb 33φΜΚ0Μρ0Β3Η Β OAHOM H3 ΑΥΧ ΠΟΑΟ)ΚΘΗΜΜ nuppOAbHOrO KOAbLļa, οοοθαημχ c aTOMOM a30Ta. 2. CoeAUHeHne corAacHO n.1, oTAnnafOLneecA τθμ, mto W πρβΑΟΤβΒΑΑθτ οοδοίί μΜβΗΟ- mam HMTporpynny, X μ Y xa>KAbiii πρθαοτθβααθτ οοδοίί χαορ, δροΜ, mam CF3i R ΠρβΑΟΤΘΒΑΒΘΤ οοδοίί φτορ, ΧΑΟρ, δρΟΜ, CF3 MAM OCF3, Μ npeACTaBAneT οοδοίί ΒΟΑοροΑ, φτορ, χαορ μαμ δροΜ, μ 24 LV 10895 L npe/ļCTaBJisieT co6oii aTOM eoflopofla mjim φτορθ.
3. CoeflMHeHne cornacHO nyHKTy 1, OTnunaioiiļeecfl τβΜ, mto oho oTBenaeT οθιμβΐί φορΜγπβ II
b κοτοροΜ A, L, M, R, W, X μ Υ ΜΜβιοτ tot >κβ CMbicn, ητο μ b nyHKTe 1.
4. CoeflMHeHne cornacHO nyHKTy 1, OTriMMaiomeecfl τβΜ, mto oho OTBeMaeT οδιι^βϋ φορΜγπβ III
b κοτοροΡί A, L, M, R, W, X μ Υ μμθκ3τ tot >κβ CMbic/i, mto μ b nyHicre 1. 5. Cnoco6 6opb6bi c HaceKOMbiMM, ηθμθτοαθμμ μ κηβιηρΜΜ, οτ/iHMaioiiļniicfl τβΜ, mto ocymecTB/isiK>T KOHTaKTHpoBaHMe yKa3aHHbix HaceKOMbix, ηθμθτοα m KnemeH, rpyHTa, b κοτοροΜ ohm Haxofl«Tc«, mx πμιαμ MJIM MeCTa o6nTaHMfl, C 3φφβΚΤΜΒΗΝΜ C TOM KM 3ρβΗΜΗ MHCeKTMLļMflHOrO, HeMaTMLļMflHOrO MJIM aKapMLļMflHOrO B03fleiiCTBMH KOJIMMeCTBOM COe/ļMHeHMfl oāuļeii φορΜγπΗ I, b κοτοροΡί A, L, M, R, W, X μ Υ μμθιοτ tot >κβ CMbicn, mto Μ B ΠγΗΚΤΘ 1. 6. Cnoco6 cornacHO n.5, οτ/iMMaioiiļMMCfl τθμ, mto yKa3aHHoe ΟΟΘΑΜΗΘΗΜΘ θ6ί11βΑ φορΜγΠΜ I ΜΜΘΘΤ CTpyKTypy, ΟΠΜΟΘΗΗγΚ) Β Π.2. 25 7. Cnoco6 3auļMTbi pacreHMM οτ ηθοθκομνχ, ηθμθτοα m κπθιαθμ, OTnuMaKDUļMiicR τθμ, mto ηθηοορτ Ha nncTBy yKa3aHHbix pacTeHnii, mjim BBOflftT B ΠΟΜΒγ ΜΠΜ ΒΟΑΥ. Ha κοτορωχ OHM npOM3paCTaK)T, 3φφθΚΤΜΒΗ0θ c TOM KM 3peHMfl MHCeKTMlļMflHOrO, ΗΘΜ3ΤΜί(ΜΑΗ0Γ0 MJ1M aKapMLļMflHOrO B03A6MCTBMB ΚΟΠΜΜΘΟΤΒΟ ΟΟΘΑΜΗΘΗΜΗ θ6ΐ!1ΘΜ φopMynbl I, B KOTOpOM A, L, Μ, R, W, X Μ Υ ΜΜβΙΟΤ TOT >ΚΘ CMbICJl, ΜΤΟ Μ β nyHKTe 1. 8. Cnoco6 cornacHO nyHKTy 7, oTJiMMaiomMMCH τθμ, mto yKa3aHHoe οοθαμηθημθ HaHocaT Ha yKa3aHHbie pacTeHMB mjim bboaat b noMBy, Ha κοτοροίί ohm npoM3pa<rraiOT, β κοπμμθοτβθ b npefle/iax οτ npMMepHO 0,125 Kr/ra flo npMMepHO 4,0 Kr/ra. 9. Cnoco6 cornacHO π.7, οτπμμθιοιαμμοβ τθμ, mto yxa3aHHoe ΟΟΘΑΜΗΘΗΜΘ ΟδίμβΜ φορΜνΠΝ I HaHOCHT Ha J)MCTBy yKa3aHHblX paCTeHMM, mjim bboabt β noMBy mjim BOfly, Ha κοτορΒίχ ohm npoM3pacTaioT, β φορΜΘ >KMflKOM Κ0ΜΠ03ΜΙ4ΜΜ, ΟΟΑβρ^ίμβΜ OT npMMepHO 10 M.fl. flO npMMepHO 10000 M.fl. yKaaaHHoro οοθαμηθημη ο6ιαθμ φopMyπbl I. 10. Cnocoč nonyMeHMfl οοθαμηθημμ, οτβθμθιοιαμχ ο6ιμβΜ φopMyJ^e I:
L
(I) B κοτοροίί A npeACTaenaeT co5oii ajiKun, coAepjKauļMM οτ 1 flo 4 θτομοβ ymepoAa, 3aMeuļeHHbiM 4 θτομθμμ raJioreHa, oahom 4MaHorpynnoii, oahom ajiKOKCMrpynnoii, coflep>KameM οτ 1 ao 4 btomob ymepoAa, Heo6fi3aTejibHO 3aMeLiļeHHOM 1-3 aTOMaMM ranoreHa mjim AayMB C1-C4 aJiKOKCM rpynnaMM, Heo6fl3aTenbHO 3aMetiļeHHbiMM 1-3 βτομθμμ rajioreHa, oahom Kap6anKOKCMrpynnoM, C0Aep>KaiiļeM οτ 1 ao 4 btomob ymepoAa, oahom 26 LV 10895 anKMJiKap6oHMJioKCMrpynnoft, co,qep>Kaiiļeii ot 1 flo 6 3tomob yrnepofla, oflHoii anKeHmiKap6oHmioKcnrpynnoii1 co^ep^ameti ot 2 flo 6 θτομοβ ymepo/ļa, oahom 6eH3onKap6oHnnoKcnrpynnoii, wjim xjiop-, flnxjiop-, rnin MeTnn3aMeiiļeHHoii 6eH3onKap6oHnnoKcnrpynnoM, a L, M, R, W, X η Y μμθκ)τ tot >κθ CMbic/i, hto m b nyHKTe 1, oTnimaioiuMiicfl τθμ, hto ocyuļecTB/iflK)T peaKUkuo οοθομηθημβ o6meti (J)opMyjibi VIII:
(VIII)
c no MeHbLuefi Mepe oahmm MonbHbiM θκβμβθπθητομ areHTa ajiKnnnpoBaHMfl o6LLļeui 0opMyxibi IX A - ranoreH (IX) b κοτοροίί A μμθθτ τοτ >κθ CMbicn, mto m paHee, b npncyTCTBMW no MeHbujePi Mepe οαηογο MonapHoro θκβμβθπθητθ οοηοβθημβ iiļenoMHoro MeTanna m pacTBopMTenn, c nonyneHneM iļenesoro coeflUHeHMii o6uļeii c£opMynbi I. 27 LV 10895 ΡΕΦΕΡΑΤ
HacTomnee μ3ο6ρθτθημθ othocmtcji k ΗβκοτορωΜ HOBbiM apminupponaM, o6/ia,qaioiiļHM MHceKTmļMflHbiMM, aKapMLļMflHbiMM m HeMaTULļMflHblMM CBOMCTBaMM H K Cn0C06y yHMHTO>KeHMfl HaceKOMblX, KneuļeM μ ηθμθτοα c ncnonb30BaHneM yKa3aHHbix npoM3BOflHbix. H3o6peieHne oTHocmcfl τβιοκθ κ cnoco6y 3auļHTbi pacTeHMii ot HaceKOMbix, Kneuļeti μ ηθμθτοα nocpeflCTBOM ηθηθοθημη Ha yKa3aHHbie pacTeHMfl min noHBy, Ha κοτοροκ ohm npon3pacTaKDT, ηοβογο npoM3BOflHoro apminnppcma B KOJIHHeCTBe, flOCTaTOHHOM C TOHKH 3peHMfl ΘΓΟ HHCeKTMLļMflHOrO, aKapHMH/ļHoro m HeMaimļMflHoro B03fleiicTBMn. HacTOPLiļee M3o6peieHne npeflycMaipnBaeT τβιοκβ cnoco6 nonyMeHna npon3BOAHbix apnnnnppona. 28

Claims (10)

1. Savienojumi ar kopējo formulu (I) kurā:
X ir F, Cl, Br, I vai CF3;
Y ir F, Cl, Br, I, CF3 vai CN;
W ir CN vai NO2;
A ir C,^.alkilgrupa, kas aizvietota ar:
4 halogēna atomiem; vienu ciāngrupu; vienu C,.4.alkoksigrupu, kas aizvietota ar 1 - 3 halogēna atomiem vai divām
C1.4.alkoksigrupām, kuras neobligāti aizvietotas ar 1 - 3 halogēna atomiem; vienu karbalkoksigrupu ar 1 - 4 oglekļa atomiem; vienu alkilkarboniloksigrupu ar 1 - 6 oglekļa atomiem; vienu alkenilkarboniloksigrupu ar 2 - 6 oglekļa atomiem; vienu benzoiloksigrupu, hlor-, dihlor- vai metilaizvietotu benzoiloksigrupu;
L ir H, F, Cl vai Br;
MunR, neatkarīgi viens no otra, ir H, C,.3.al kilgrupa, C,.3.alkoksigrupa, Cļ_3_alkiItiogrupa, C,.3.alkilsulfiniIgrupa, Cļ.3.alkilsulfoniIgrupa, ciāngrupa, F, Cl, Br, I, nitrogrupa, CF3, grupa R’CFjZ, R2CO, vai -NR3R4, pie kam , ja M un R atrodas blakus stāvoklī, tie, kopā ar cikla oglekļa atomiem, pi kuriem tie pievienoti, var veidot ciklu, kurā MunR atbilst grupas:
-OCH2O-, -OCF2O- vai
Z ir S(O)n vai O;
R1 ir H, F, CHF2, CHFCI vai CF3;
R2 ir Cļ_3.alkilgrupa, Cļ.3.alkoksigrupa, vai grupa -NR3R4;
R3 ir H, Cļ.3.alkilgrupa;
R4 ir H, Cļ_3_alkiIgrupa vai R5CO;
R ir H vai Cļ.3.alkilgrupa;
n ir vesels skaitlis 0, 1 vai 2, ar tādu noteikumu, ka tad, kad X un Y ir ūdeņraža atoms, bet A ir C,_ļ.alkiIgrupa, kura aizvietota ar vienu ciāngrupu, aizvietotājs atrodas pie viena no diviem pirola slāpekļa atomam blakusesošajiem atomiem.
2. Savienojums pēc punkta 1, kas a t š ķ i r a s ar to, ka tajā W ir CN vai NO2; X un Y , neatkarīgi viens no otra, ir Cl, Br vai CF3; R ir F, Cl, Br, CF3 vai OCF3; M ir H, F, Cl vai Br, un L ir H vai F.
3. Savienojums pēc punkta 1, kas a t š ķ i r a s ar to, ka tas atbilst kopējai formulai (II) kurā A, L, M, R, W, X un Y nozīmes atbilst punktā 1 minētajām.
4. Savienojums pēc punkta 1, kas a t š ķ i r a s ar to, ka tas atbilst kopējai formulai (III) (III) kurā A, L, M, R, W, X un Y nozīmes atbilst punktā 1 minētajām.
5. Paņēmiens insektu, ērču un nematodu apkarošanai, kas a t š ķ i r a s ar to, ka minētos insektus, ērces un nematodes, to vairošanās vietas vai uzturēšanās vietas kontaktē ar pret insektiem, ērcēm vai nematodēm efektīvi darbojošos daudzumu savienojuma ar formulu (I), kurā A, L, M, R, W, X un Y nozīmes atbilst punktā 1 minētajām.
6. Paņēmiens pēc punkta 5, kas a t š ķ i r a s ar to, ka minēta savienojuma ar formulu (I) struktūra atbilst punktā 2 dotajai.
7. Paņēmiens kultivējamo augu aizsardzībai no insektiem, ērcēm un nematodēm, kas a t š ķ i r a s ar to, ka uz minēto augu virszemes daļām, uz augsni vai ūdeni, kurā šie augi aug, uznes pret insektiem, ērcēm vai nematodēm efektīvi darbojošos daudzumu savienojuma ar formulu (I), kurā A, L, M, R, W, X un Y nozīmes atbilst punktā 1 minētajām.
8. Paņēmiens pēc punkta 7, kas a t š ķ i r a s ar to, ka minēto savienojumu ar formulu (I) uznes uz minētajiem augiem vai augsni, kurā tos audzē, devā no apmēram 0,125 kg/ha līdz 4,0 kg/ha.
9. Paņēmiens pēc punkta 7, kas a t š ķ i r a s ar to, ka minēto savienojumu ar formulu (I) uznes uz minēto augu virszemes daļām, vai uz augsni vai ūdeni, kurā tos audzē, šķidras kompozīcijas veidā, kas aptuveni satur no 10 līdz 10 000 daļām uz miljonu minētā savienojuma ar formulu (I).
10. Paņēmiens savienojumu ar kopējo formulu (I) kurā:
A ir Cļ.4.alkilgrupa, kas aizvietota ar:
4 halogēna atomiem; vienu ciāngrupu; vienu C1,4„alkoksigrupu, kas aizvietota ar 1-3 halogēna atomiem vai divām Cļ^.alkoksigrupām, kuras neobligāti aizvietotas ar 1 - 3 halogēna atomiem; vienu karbalkoksigrupu ar 1 - 4 oglekļa atomiem; vienu alkilkarboniloksigrupu ar 1 - 6 oglekļa atomiem; vienu alkenilkarboniloksigrupu ar 2 - 6 oglekļa atomiem; vienu benzoiloksigrupu, hlor-, dihlor- vai metilaizvietotu benzoiloksigrupu;
bet L, M, R, W, X un Y nozīmes atbilst punktā 1 dotajām, iegūšanai, kas a t š ķ i r a s ar to, ka veic reakciju starp savienojumu ar un vismaz vienu molāro ekvivalentu alkilējošā aģenta ar kopējo formulu (IX)
A-halogēns (IX) kurā A nozīme atbilst punktā 1 jau minētajai, vismaz viena molārā ekvivalenta sārma metāla hidroksīda klātienē, šķīdinātājā, iegūstot vēlamo savienojumu ar kopējo formulu (I).
LVP-93-1061A 1989-08-11 1993-09-09 Arylpyrrole derivatives, struggle method against insekts, ticks and nematodes, process for preparing of derivatives of arylpirrole LV10895B (en)

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