LV10720A - Peptidi un farmaceitiska kompozicija uz to bazes - Google Patents

Peptidi un farmaceitiska kompozicija uz to bazes

Info

Publication number
LV10720A
LV10720A LV920701A LV920701A LV10720A LV 10720 A LV10720 A LV 10720A LV 920701 A LV920701 A LV 920701A LV 920701 A LV920701 A LV 920701A LV 10720 A LV10720 A LV 10720A
Authority
LV
Latvia
Prior art keywords
amino acid
peptides
bradykinin
direct bond
optionally
Prior art date
Application number
LV920701A
Other languages
English (en)
Other versions
LV10720B (en
Inventor
Stephan Henke
Hiristo Anagnostopulos
Gerhard Breipohl
Jochen Knolle
Jens Stechl
Bernward Schoelkens
Hans-Wolfram Fehlhaber
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of LV10720A publication Critical patent/LV10720A/lv
Publication of LV10720B publication Critical patent/LV10720B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
LVP-92-701A 1988-11-24 1992-12-23 Peptides and pharmaceutical composition containing them LV10720B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3839581 1988-11-24
DE3916291 1989-05-19
DE3918225 1989-06-03

Publications (2)

Publication Number Publication Date
LV10720A true LV10720A (lv) 1995-06-20
LV10720B LV10720B (en) 1996-02-20

Family

ID=27198531

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-92-701A LV10720B (en) 1988-11-24 1992-12-23 Peptides and pharmaceutical composition containing them

Country Status (26)

Country Link
EP (1) EP0370453B1 (lv)
JP (1) JPH07121956B2 (lv)
KR (1) KR0139632B1 (lv)
CN (1) CN1035006C (lv)
AT (1) ATE107318T1 (lv)
AU (1) AU612054B2 (lv)
CA (1) CA1340667C (lv)
CY (2) CY2028A (lv)
CZ (1) CZ282384B6 (lv)
DE (3) DE3938751A1 (lv)
DK (1) DK175344B1 (lv)
ES (1) ES2057071T3 (lv)
FI (1) FI94353C (lv)
HK (1) HK1006716A1 (lv)
HU (2) HU210566B (lv)
IE (1) IE63490B1 (lv)
IL (1) IL91298A (lv)
LU (1) LU91499I2 (lv)
LV (1) LV10720B (lv)
MX (1) MX9203277A (lv)
NL (1) NL300359I2 (lv)
NO (2) NO177597C (lv)
NZ (1) NZ230244A (lv)
PH (1) PH31009A (lv)
PT (1) PT91692B (lv)
SK (1) SK490689A3 (lv)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
US5648333A (en) * 1988-11-24 1997-07-15 Hoechst Aktiengesellschaft Peptides having bradykinin antagonist action
WO1991009055A1 (en) * 1989-12-08 1991-06-27 Boston University Acylated bradykinin antagonists and uses therefor
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
US5843900A (en) * 1991-04-01 1998-12-01 Cortech, Inc. Bradykinin antagonists
US5416191A (en) * 1991-04-01 1995-05-16 Cortech, Inc. Bradykinin antagonists
US6770741B1 (en) 1991-04-19 2004-08-03 Scios Inc. Bradykinin antagonist peptides
EP0618810B1 (en) * 1991-04-19 2001-07-04 Scios Nova Inc. Bradykinin antagonist peptides
CA2106768C (en) * 1991-04-19 2000-09-19 Donald J. Kyle Bradykinin type peptides
HUT63060A (en) * 1991-08-22 1993-07-28 Hoechst Ag Process for producing pharmaceutical compositions locally applicable on nose and eye, comprising bradykinin antagonists
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
WO1993011789A1 (en) 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
TW199863B (lv) * 1991-12-21 1993-02-11 Hoechst Ag
WO1993017701A1 (en) * 1992-03-12 1993-09-16 The Administrators Of The Tulane Educational Fund Endothelin receptor-binding peptides
TW258739B (lv) * 1992-04-04 1995-10-01 Hoechst Ag
FR2692581B1 (fr) * 1992-06-18 1994-08-19 Adir Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5541286A (en) * 1992-10-08 1996-07-30 Scios Nova Inc. Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids
US5686565A (en) * 1992-10-08 1997-11-11 Scios Inc. Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
US5610142A (en) * 1992-10-08 1997-03-11 Scios Inc. Bradykinin antagonist pseudopeptide derivatives of substituted 4-keto-1,3,8-triazaspiro[4.5]decan-3-alkanoic acids
IL107400A0 (en) * 1992-11-10 1994-01-25 Cortech Inc Bradykinin antagonists
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
US5817756A (en) * 1993-09-09 1998-10-06 Scios Inc. Pseudo- and non-peptide bradykinin receptor antagonists
DE4345062A1 (de) * 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
EP0813544B1 (en) * 1994-03-09 2004-10-27 Cortech, Inc. Bradykinin antagonist peptides incorporating n-substituted glycines
US6407059B1 (en) 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
IL109943A (en) 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
EP0832106A2 (en) * 1995-06-05 1998-04-01 Cortech, Inc. Compounds having bradykinin antagonistic activity and mu-opioid agonistic activity
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
FR2737408B1 (fr) * 1995-07-31 1997-09-05 Oreal Utilisation d'un antagoniste de bradykinine dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue
US5849863A (en) * 1995-09-08 1998-12-15 University Of Colorado Cytolytic bradykinin antagonists
US5834431A (en) * 1995-09-08 1998-11-10 Cortech, Inc. Des-Arg9 -BK antagonists
FR2739553B1 (fr) * 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
DE19642289A1 (de) 1996-10-14 1998-04-16 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit
DE10304994A1 (de) * 2003-02-07 2004-09-02 Aventis Pharma Deutschland Gmbh Die Verwendung von Antagonisten des Bradykinin-B2 Rezeptors zur Behandlung von Osteoarthrose
CN102532267B (zh) * 2012-02-09 2014-06-18 深圳翰宇药业股份有限公司 一种艾替班特的制备方法
CN104043101B (zh) * 2014-05-23 2016-04-20 杭州阿德莱诺泰制药技术有限公司 一种艾替班特注射用组合物及其制备方法和制剂
KR102099509B1 (ko) 2018-07-27 2020-04-09 강경순 과수용 받침지주
CN111944016B (zh) * 2020-08-25 2022-04-29 台州吉诺生物科技有限公司 一种醋酸艾替班特的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3044236A1 (de) * 1980-11-25 1982-06-16 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
FR2575753B1 (fr) * 1985-01-07 1987-02-20 Adir Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides

Also Published As

Publication number Publication date
CZ490689A3 (en) 1997-03-12
FI893738A0 (fi) 1989-08-08
JPH02184697A (ja) 1990-07-19
PH31009A (en) 1997-12-23
PT91692A (pt) 1990-03-30
AU612054B2 (en) 1991-06-27
NL300359I1 (nl) 2008-11-03
CY2028A (en) 1998-02-20
KR0139632B1 (ko) 1998-07-01
DE3938751A1 (de) 1990-05-31
EP0370453B1 (de) 1994-06-15
NO893193L (no) 1990-05-25
EP0370453A3 (de) 1991-12-04
SK279315B6 (sk) 1998-09-09
PT91692B (pt) 1995-05-31
DE122008000066I1 (de) 2009-05-20
NO177597C (no) 1995-10-18
CY2008022I2 (el) 2009-11-04
CA1340667C (en) 1999-07-20
CZ282384B6 (cs) 1997-07-16
JPH07121956B2 (ja) 1995-12-25
FI94353B (fi) 1995-05-15
NO2008016I1 (no) 2008-11-17
DK384089D0 (da) 1989-08-04
NZ230244A (en) 1992-06-25
CY2008022I1 (el) 2009-11-04
IE892522L (en) 1990-05-24
DE122008000066I2 (de) 2009-11-05
HU210566B (en) 1995-05-29
DK175344B1 (da) 2004-08-30
HU210712A9 (en) 1995-06-28
KR900007870A (ko) 1990-06-02
FI94353C (fi) 1995-08-25
ES2057071T3 (es) 1994-10-16
LV10720B (en) 1996-02-20
HUT52527A (en) 1990-07-28
IE63490B1 (en) 1995-05-03
CN1035006C (zh) 1997-05-28
IL91298A0 (en) 1990-03-19
IL91298A (en) 1994-05-30
NO177597B (no) 1995-07-10
NO2008016I2 (no) 2012-10-01
ATE107318T1 (de) 1994-07-15
AU3943189A (en) 1990-05-31
CN1042918A (zh) 1990-06-13
DE58907889D1 (de) 1994-07-21
DK384089A (da) 1990-05-25
FI893738A (fi) 1990-05-25
LU91499I2 (fr) 2009-01-19
HK1006716A1 (en) 1999-03-12
EP0370453A2 (de) 1990-05-30
SK490689A3 (en) 1998-09-09
NL300359I2 (nl) 2009-02-02
MX9203277A (es) 1992-07-01
NO893193D0 (no) 1989-08-08

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