CY2028A - Peptides having a brady kinine-inhibiting activity - Google Patents

Peptides having a brady kinine-inhibiting activity

Info

Publication number
CY2028A
CY2028A CY202898A CY202898A CY2028A CY 2028 A CY2028 A CY 2028A CY 202898 A CY202898 A CY 202898A CY 202898 A CY202898 A CY 202898A CY 2028 A CY2028 A CY 2028A
Authority
CY
Cyprus
Prior art keywords
amino acid
peptides
bradykinin
direct bond
optionally
Prior art date
Application number
CY202898A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CY2028A publication Critical patent/CY2028A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/18—Kallidins; Bradykinins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
CY202898A 1988-11-24 1998-02-20 Peptides having a brady kinine-inhibiting activity CY2028A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE3839581 1988-11-24
DE3916291 1989-05-19
DE3918225 1989-06-03

Publications (1)

Publication Number Publication Date
CY2028A true CY2028A (en) 1998-02-20

Family

ID=27198531

Family Applications (2)

Application Number Title Priority Date Filing Date
CY202898A CY2028A (en) 1988-11-24 1998-02-20 Peptides having a brady kinine-inhibiting activity
CY200800022C CY2008022I1 (el) 1988-11-24 2008-12-30 Peptides having a brady kinine-inhibiting activity

Family Applications After (1)

Application Number Title Priority Date Filing Date
CY200800022C CY2008022I1 (el) 1988-11-24 2008-12-30 Peptides having a brady kinine-inhibiting activity

Country Status (26)

Country Link
EP (1) EP0370453B1 (xx)
JP (1) JPH07121956B2 (xx)
KR (1) KR0139632B1 (xx)
CN (1) CN1035006C (xx)
AT (1) ATE107318T1 (xx)
AU (1) AU612054B2 (xx)
CA (1) CA1340667C (xx)
CY (2) CY2028A (xx)
CZ (1) CZ282384B6 (xx)
DE (3) DE58907889D1 (xx)
DK (1) DK175344B1 (xx)
ES (1) ES2057071T3 (xx)
FI (1) FI94353C (xx)
HK (1) HK1006716A1 (xx)
HU (2) HU210566B (xx)
IE (1) IE63490B1 (xx)
IL (1) IL91298A (xx)
LU (1) LU91499I2 (xx)
LV (1) LV10720B (xx)
MX (1) MX9203277A (xx)
NL (1) NL300359I2 (xx)
NO (2) NO177597C (xx)
NZ (1) NZ230244A (xx)
PH (1) PH31009A (xx)
PT (1) PT91692B (xx)
SK (1) SK490689A3 (xx)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648333A (en) * 1988-11-24 1997-07-15 Hoechst Aktiengesellschaft Peptides having bradykinin antagonist action
DE4013270A1 (de) * 1990-04-26 1991-10-31 Hoechst Ag Peptide mit bradykinin-antagonistischer wirkung
DE69012142D1 (de) * 1989-12-08 1994-10-06 Univ Boston Acylierte bradykininantagonisten und deren verwendung.
MX9100717A (es) * 1990-08-24 1992-04-01 Syntex Inc Antagonistas de la bradiquinina
US5843900A (en) * 1991-04-01 1998-12-01 Cortech, Inc. Bradykinin antagonists
US5416191A (en) * 1991-04-01 1995-05-16 Cortech, Inc. Bradykinin antagonists
US6770741B1 (en) 1991-04-19 2004-08-03 Scios Inc. Bradykinin antagonist peptides
EP0618809B1 (en) 1991-04-19 1998-08-19 Scios Nova Inc. Bradykinin type peptides
JPH07504155A (ja) * 1991-04-19 1995-05-11 シオス・ノヴァ・インコーポレイテット ブラジキニンアンタゴニストペプチド
HUT63060A (en) * 1991-08-22 1993-07-28 Hoechst Ag Process for producing pharmaceutical compositions locally applicable on nose and eye, comprising bradykinin antagonists
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
WO1993011789A1 (en) 1991-12-12 1993-06-24 Scios Nova Inc. Modified position (7) bradykinin antagonist peptides
TW199863B (xx) * 1991-12-21 1993-02-11 Hoechst Ag
WO1993017701A1 (en) * 1992-03-12 1993-09-16 The Administrators Of The Tulane Educational Fund Endothelin receptor-binding peptides
TW258739B (xx) * 1992-04-04 1995-10-01 Hoechst Ag
FR2692581B1 (fr) * 1992-06-18 1994-08-19 Adir Nouveaux dérivés peptidiques à activité antagoniste de la bradykinine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5610142A (en) * 1992-10-08 1997-03-11 Scios Inc. Bradykinin antagonist pseudopeptide derivatives of substituted 4-keto-1,3,8-triazaspiro[4.5]decan-3-alkanoic acids
US5521158A (en) * 1992-10-08 1996-05-28 Scios Nova Inc. Pseudopeptide bradykinin receptor antagonists
US5541286A (en) * 1992-10-08 1996-07-30 Scios Nova Inc. Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids
US5686565A (en) * 1992-10-08 1997-11-11 Scios Inc. Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins
IL107400A0 (en) * 1992-11-10 1994-01-25 Cortech Inc Bradykinin antagonists
WO1994019372A1 (en) * 1993-02-17 1994-09-01 Scios Nova Inc. Cyclic bradykinin antagonist peptides
US5817756A (en) * 1993-09-09 1998-10-06 Scios Inc. Pseudo- and non-peptide bradykinin receptor antagonists
DE4345062A1 (de) * 1993-12-31 1995-07-13 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von Viruserkrankungen
KR100360639B1 (ko) * 1994-03-09 2003-01-30 코르텍, 인크. N-치환글리신함유브라디키닌길항제펩티드
IL109943A (en) * 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
US6407059B1 (en) 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
WO1996039425A2 (en) * 1995-06-05 1996-12-12 Cortech, Inc. Compounds having bradykinin antagonistic activity and mu-opioid agonistic activity
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
FR2737408B1 (fr) * 1995-07-31 1997-09-05 Oreal Utilisation d'un antagoniste de bradykinine dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue
US5849863A (en) * 1995-09-08 1998-12-15 University Of Colorado Cytolytic bradykinin antagonists
US5834431A (en) * 1995-09-08 1998-11-10 Cortech, Inc. Des-Arg9 -BK antagonists
FR2739553B1 (fr) 1995-10-06 1998-01-02 Oreal Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
DE19642289A1 (de) 1996-10-14 1998-04-16 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit
DE10304994A1 (de) * 2003-02-07 2004-09-02 Aventis Pharma Deutschland Gmbh Die Verwendung von Antagonisten des Bradykinin-B2 Rezeptors zur Behandlung von Osteoarthrose
CN102532267B (zh) * 2012-02-09 2014-06-18 深圳翰宇药业股份有限公司 一种艾替班特的制备方法
CN104043101B (zh) * 2014-05-23 2016-04-20 杭州阿德莱诺泰制药技术有限公司 一种艾替班特注射用组合物及其制备方法和制剂
KR102099509B1 (ko) 2018-07-27 2020-04-09 강경순 과수용 받침지주
CN111944016B (zh) * 2020-08-25 2022-04-29 台州吉诺生物科技有限公司 一种醋酸艾替班特的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3044236A1 (de) * 1980-11-25 1982-06-16 Hoechst Ag, 6000 Frankfurt Aminosaeurederivate und verfahren zu ihrer herstellung
FR2487829A2 (fr) * 1979-12-07 1982-02-05 Science Union & Cie Nouveaux imino acides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
DE3227055A1 (de) * 1982-07-20 1984-01-26 Hoechst Ag, 6230 Frankfurt Neue derivate der 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-aza-bicyclo(2.2.2)octan-3-carbonsaeure als zwischenstufe und verfahren zu deren herstellung
FR2575753B1 (fr) * 1985-01-07 1987-02-20 Adir Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US4693993A (en) * 1985-06-13 1987-09-15 Stewart John M Bradykinin antagonist peptides

Also Published As

Publication number Publication date
AU612054B2 (en) 1991-06-27
EP0370453A2 (de) 1990-05-30
HU210566B (en) 1995-05-29
SK279315B6 (sk) 1998-09-09
NO177597C (no) 1995-10-18
FI94353C (fi) 1995-08-25
CN1042918A (zh) 1990-06-13
HU210712A9 (en) 1995-06-28
NO177597B (no) 1995-07-10
DK175344B1 (da) 2004-08-30
FI893738A0 (fi) 1989-08-08
EP0370453B1 (de) 1994-06-15
CY2008022I2 (el) 2009-11-04
AU3943189A (en) 1990-05-31
NO893193L (no) 1990-05-25
PH31009A (en) 1997-12-23
KR900007870A (ko) 1990-06-02
KR0139632B1 (ko) 1998-07-01
CA1340667C (en) 1999-07-20
DE58907889D1 (de) 1994-07-21
LV10720B (en) 1996-02-20
CZ490689A3 (en) 1997-03-12
HK1006716A1 (en) 1999-03-12
JPH07121956B2 (ja) 1995-12-25
NO2008016I1 (no) 2008-11-17
IL91298A0 (en) 1990-03-19
FI893738A (fi) 1990-05-25
FI94353B (fi) 1995-05-15
EP0370453A3 (de) 1991-12-04
PT91692B (pt) 1995-05-31
JPH02184697A (ja) 1990-07-19
NO2008016I2 (no) 2012-10-01
SK490689A3 (en) 1998-09-09
NL300359I2 (nl) 2009-02-02
DK384089A (da) 1990-05-25
CY2008022I1 (el) 2009-11-04
LU91499I2 (fr) 2009-01-19
NZ230244A (en) 1992-06-25
DE122008000066I2 (de) 2009-11-05
DK384089D0 (da) 1989-08-04
CZ282384B6 (cs) 1997-07-16
IE892522L (en) 1990-05-24
HUT52527A (en) 1990-07-28
MX9203277A (es) 1992-07-01
DE3938751A1 (de) 1990-05-31
PT91692A (pt) 1990-03-30
ES2057071T3 (es) 1994-10-16
IE63490B1 (en) 1995-05-03
DE122008000066I1 (de) 2009-05-20
NO893193D0 (no) 1989-08-08
CN1035006C (zh) 1997-05-28
LV10720A (lv) 1995-06-20
NL300359I1 (nl) 2008-11-03
ATE107318T1 (de) 1994-07-15
IL91298A (en) 1994-05-30

Similar Documents

Publication Publication Date Title
HK1006716A1 (en) Peptides having a brady kinine-inhibiting activity
CY2029A (en) Peptide antagonists of bradykinin
LV10290A (lv) Peptidi ar bradkinina antagonista darbibu