LU91368I2 - Fésotérodine et ses sels avec des acides physiologiquement acceptables y compris l'acide fumarique (TOVIAZ) - Google Patents

Fésotérodine et ses sels avec des acides physiologiquement acceptables y compris l'acide fumarique (TOVIAZ)

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Publication number
LU91368I2
LU91368I2 LU91368C LU91368C LU91368I2 LU 91368 I2 LU91368 I2 LU 91368I2 LU 91368 C LU91368 C LU 91368C LU 91368 C LU91368 C LU 91368C LU 91368 I2 LU91368 I2 LU 91368I2
Authority
LU
Luxembourg
Prior art keywords
toviaz
fesoterodine
salts
fumaric acid
physiologically acceptable
Prior art date
Application number
LU91368C
Other languages
English (en)
Other versions
LU91368I9 (fr
Original Assignee
Pfizer Health Ab
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20406354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU91368(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Health Ab filed Critical Pfizer Health Ab
Publication of LU91368I2 publication Critical patent/LU91368I2/fr
Publication of LU91368I9 publication Critical patent/LU91368I9/fr

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    • C07—ORGANIC CHEMISTRY
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    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/03—Monoamines
    • C07C211/06—Monoamines containing only n- or iso-propyl groups
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
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    • C07C215/80—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton of the same non-condensed six-membered aromatic ring containing at least two amino groups bound to the carbon skeleton
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    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
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    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
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LU91368C 1997-03-27 2007-09-26 Fésotérodine et ses sels avec des acides physiologiquement acceptables y compris l'acide fumarique (TOVIAZ) LU91368I2 (fr)

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SE9701144A SE9701144D0 (sv) 1997-03-27 1997-03-27 Novel compounds, their use and preparation
PCT/SE1998/000556 WO1998043942A1 (fr) 1997-03-27 1998-03-26 Nouveaux composes, leur utilisation et leur preparation

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DE10315917A1 (de) 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
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WO2005012227A2 (fr) * 2003-08-05 2005-02-10 Ranbaxy Laboratories Limited Procede de preparation de 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, un metabolite de la tolterodine
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
CA2569238A1 (fr) * 2004-06-01 2005-12-15 F. Hoffmann-La Roche Ag Inhibiteur du recaptage des monoamines
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BRPI0713314A2 (pt) 2006-06-20 2012-03-06 Lek Pharmaceuticals D.D. Processo para a preparação de 3-(2-hidróxi-5-fenil substituído)-n-alquil-3-fenilpropilaminas
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EP2281801B1 (fr) * 2009-07-27 2014-01-08 Crystal Pharma, S.A.U. Procédé pour la préparation de 3,3-diphénylpropylamines
WO2011048409A1 (fr) 2009-10-20 2011-04-28 Astrazeneca Ab Dérivés d'amine cyclique ayant une activité agoniste de récepteur adrénergique bêta-2 et antagoniste de récepteur muscarinique
EP2364966A1 (fr) * 2010-03-09 2011-09-14 LEK Pharmaceuticals d.d. Procédé pour la préparation de 3-(2-hydroxy-5-substitue phényl)-3-phénylpropylamines, intermédiaires pour la préparation de tolterodine
CZ2010997A3 (cs) * 2010-12-30 2012-02-08 Zentiva, K.S. Zpusob výroby (2R,3R)-N,N-dimethyl-3-(3-hydroxyfenyl)-2-methylpentylaminu (tapentadolu)
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ES2199433T5 (es) 2008-03-01
NO994438L (no) 1999-11-26
ES2199433T3 (es) 2004-02-16
MY129473A (en) 2007-04-30
KR20000076314A (ko) 2000-12-26
NZ337967A (en) 2001-01-26
JP2001522355A (ja) 2001-11-13
CA2284977A1 (fr) 1998-10-08
SI1019358T2 (sl) 2008-02-29
CN100482635C (zh) 2009-04-29
DK1019358T3 (da) 2003-09-01
EP1019358A1 (fr) 2000-07-19
ATE239693T1 (de) 2003-05-15
EP1019358B1 (fr) 2003-05-07
US6313132B1 (en) 2001-11-06
KR100774692B1 (ko) 2007-11-08
HK1078561A1 (en) 2006-03-17
PT1019358E (pt) 2003-09-30
DE69814431T3 (de) 2008-05-08
TW555735B (en) 2003-10-01
CN1636967A (zh) 2005-07-13
NO314724B1 (no) 2003-05-12
SI1019358T1 (en) 2003-10-31
BR9808069B8 (pt) 2018-05-22
BRPI9808069B8 (pt) 2018-05-22
BR9808069A (pt) 2000-03-08
AU739186B2 (en) 2001-10-04
EP1019358B2 (fr) 2007-09-12
NL300295I2 (nl) 2008-03-03
BR9808069B1 (pt) 2012-10-30
JP4187274B2 (ja) 2008-11-26
DE69814431T2 (de) 2004-04-15
CN1251569A (zh) 2000-04-26
NO994438D0 (no) 1999-09-13
WO1998043942A1 (fr) 1998-10-08
FR07C0049I1 (fr) 2007-11-16
FR07C0049I2 (fr) 2008-05-09
DE69814431D1 (de) 2003-06-12
AU6755298A (en) 1998-10-22
ZA982478B (en) 1998-10-08
DK1019358T4 (da) 2008-01-14
DE122007000067I1 (de) 2008-03-27
AR014868A1 (es) 2001-04-11
CA2284977C (fr) 2008-02-05
SE9701144D0 (sv) 1997-03-27
LU91368I9 (fr) 2018-12-31
NL300295I1 (nl) 2007-12-03

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