LU86022A1 - Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique - Google Patents

Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique Download PDF

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Publication number
LU86022A1
LU86022A1 LU86022A LU86022A LU86022A1 LU 86022 A1 LU86022 A1 LU 86022A1 LU 86022 A LU86022 A LU 86022A LU 86022 A LU86022 A LU 86022A LU 86022 A1 LU86022 A1 LU 86022A1
Authority
LU
Luxembourg
Prior art keywords
radical
formula
alkyl radical
compounds according
carbon atoms
Prior art date
Application number
LU86022A
Other languages
English (en)
French (fr)
Inventor
Shroot Braham
Eustache Jacques
Watts Olivier
Original Assignee
Cird
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cird filed Critical Cird
Priority to LU86022A priority Critical patent/LU86022A1/fr
Priority to NO862966A priority patent/NO166936C/no
Priority to IL79506A priority patent/IL79506A0/xx
Priority to NZ216963A priority patent/NZ216963A/xx
Priority to CA000514631A priority patent/CA1271422A/fr
Priority to DK352486A priority patent/DK170769B1/da
Priority to ES8601337A priority patent/ES2002727A6/es
Priority to JP61175471A priority patent/JP2614606B2/ja
Priority to AU60499/86A priority patent/AU596109C/en
Priority to PT83056A priority patent/PT83056B/pt
Priority to GR861950A priority patent/GR861950B/el
Priority to FI863036A priority patent/FI87454C/fi
Priority to CA000514630A priority patent/CA1269371A/fr
Priority to DE8686401671T priority patent/DE3685528T2/de
Priority to DE198686401671T priority patent/DE210929T1/de
Priority to EP86401671A priority patent/EP0210929B1/de
Priority to AT86401671T priority patent/ATE76864T1/de
Priority to ZA865572A priority patent/ZA865572B/xx
Publication of LU86022A1 publication Critical patent/LU86022A1/fr
Priority to CA000615615A priority patent/CA1297127C/fr
Priority to NO900384A priority patent/NO167911C/no
Priority to NO900385A priority patent/NO167732C/no
Priority to US07/580,916 priority patent/US5124473A/en
Priority to DK91655A priority patent/DK65591D0/da
Priority to US07/859,046 priority patent/US5434180A/en
Priority to US08/421,235 priority patent/US5602104A/en
Priority to US08/725,496 priority patent/US5686586A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/49—Polycyclic acids containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
LU86022A 1985-07-25 1985-07-25 Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique LU86022A1 (fr)

Priority Applications (26)

Application Number Priority Date Filing Date Title
LU86022A LU86022A1 (fr) 1985-07-25 1985-07-25 Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique
NO862966A NO166936C (no) 1985-07-25 1986-07-23 Polycykliske aromatiske, kosmetiske forbindelser, og deres anvendelse i kosmetiske blandinger.
IL79506A IL79506A0 (en) 1985-07-25 1986-07-24 Polycyclic aromatic compounds,their preparation and pharmaceutical and cosmetic compositions containing them
NZ216963A NZ216963A (en) 1985-07-25 1986-07-24 Polycyclic aromatic compounds: pharmaceutical and cosmetic compositions
CA000514631A CA1271422A (fr) 1985-07-25 1986-07-24 Compositions pharmaceutiques
DK352486A DK170769B1 (da) 1985-07-25 1986-07-24 Aromatiske polycycliske forbindelser, deres fremstilling og farmaceutiske og kosmetiske præparater deraf
ES8601337A ES2002727A6 (es) 1985-07-25 1986-07-24 Procedimiento de preparacion de derivados aromaticos policiclicos
JP61175471A JP2614606B2 (ja) 1985-07-25 1986-07-24 多環式芳香族誘導体、その製造方法並びに医薬および化粧領域における適用
AU60499/86A AU596109C (en) 1985-07-25 1986-07-24 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same
PT83056A PT83056B (pt) 1985-07-25 1986-07-24 Processo para a preparacao de derivados aromaticos policiclicos designadamente do acido p-(6-tert-butil-2-naftii)benzoico e dos seus sais e sua aplicacao nos dominios farmaceuticos e cosmeticos
GR861950A GR861950B (en) 1985-07-25 1986-07-24 Polycyclic aromatic derivatives method for preparing them and applications for pharmaceutical and cosmetical uses
FI863036A FI87454C (fi) 1985-07-25 1986-07-24 Polycykliska aromatiska derivat, deras framstaellningsfoerfarande och tillaempning inom kosmetik
CA000514630A CA1269371A (fr) 1985-07-25 1986-07-24 Derives aromatiques polycycliques et utilisation de ceux-ci dans le domaine cosmetique
DE8686401671T DE3685528T2 (de) 1985-07-25 1986-07-25 Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen.
DE198686401671T DE210929T1 (de) 1985-07-25 1986-07-25 Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen.
EP86401671A EP0210929B1 (de) 1985-07-25 1986-07-25 Aromatische polycyclische Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung in pharmazeutischen und kosmetischen Zubereitungen
AT86401671T ATE76864T1 (de) 1985-07-25 1986-07-25 Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen.
ZA865572A ZA865572B (en) 1985-07-25 1986-07-25 Polycyclic aromatic derivatives,process for preparing the same and pharmaceutical and cosmetic compositions containing the same
CA000615615A CA1297127C (fr) 1985-07-25 1990-01-22 Derives aromatiques polycycliques et utilisation de ceux-ci dans le domaine cosmetique
NO900385A NO167732C (no) 1985-07-25 1990-01-26 Analogifremgangsmaate ved fremstilling av terapeutisk aktive, aromatiske, polycykliske derivater.
NO900384A NO167911C (no) 1985-07-25 1990-01-26 Polycykliske retinoider
US07/580,916 US5124473A (en) 1985-07-25 1990-09-12 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same
DK91655A DK65591D0 (da) 1985-07-25 1991-04-11 1-phenyl-1-buten-derivater og fremgangsmaade til deres fremstilling
US07/859,046 US5434180A (en) 1985-07-25 1992-03-27 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same
US08/421,235 US5602104A (en) 1985-07-25 1995-04-13 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same
US08/725,496 US5686586A (en) 1985-07-25 1996-10-04 Polycyclic aromatic derivatives, process for preparing the same and pharmaceutical and cosmetic compositions containing the same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU86022A LU86022A1 (fr) 1985-07-25 1985-07-25 Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique
LU86022 1985-07-25

Publications (1)

Publication Number Publication Date
LU86022A1 true LU86022A1 (fr) 1987-02-04

Family

ID=19730521

Family Applications (1)

Application Number Title Priority Date Filing Date
LU86022A LU86022A1 (fr) 1985-07-25 1985-07-25 Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique

Country Status (16)

Country Link
US (4) US5124473A (de)
EP (1) EP0210929B1 (de)
JP (1) JP2614606B2 (de)
AT (1) ATE76864T1 (de)
CA (3) CA1269371A (de)
DE (2) DE3685528T2 (de)
DK (2) DK170769B1 (de)
ES (1) ES2002727A6 (de)
FI (1) FI87454C (de)
GR (1) GR861950B (de)
IL (1) IL79506A0 (de)
LU (1) LU86022A1 (de)
NO (1) NO166936C (de)
NZ (1) NZ216963A (de)
PT (1) PT83056B (de)
ZA (1) ZA865572B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988000466A1 (en) * 1986-07-16 1988-01-28 Kligman Albert M Methods for treatment of sundamaged human skin with retinoids
LU87040A1 (fr) * 1987-11-04 1989-06-14 Oreal Esters aromatiques polycycliques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant
FR2635683B1 (fr) * 1988-09-01 1990-11-09 Cird Nouveau compose marque au tritium, sa preparation et son application notamment dans la determination de l'affinite des retinoides pour leurs recepteurs nucleaires et leur proteine de liaison cytosolique
US5146025A (en) * 1989-02-28 1992-09-08 Mitsubishi Gas Chemical Company, Inc. Naphthalene compounds
US5324840A (en) * 1992-06-11 1994-06-28 Allergan, Inc. Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects
US5466861A (en) * 1992-11-25 1995-11-14 Sri International Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors
US6172115B1 (en) 1993-02-11 2001-01-09 Allergan Sales, Inc. Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid
US5455265A (en) * 1993-02-11 1995-10-03 Allergan, Inc. Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors
US5399586A (en) * 1993-03-11 1995-03-21 Allergan, Inc. Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity
FR2713640B1 (fr) * 1993-12-15 1996-01-05 Cird Galderma Nouveaux composés aromatiques polycycliques, compositions pharmaceutiques et cosmétiques les contenant et utilisations.
AU2823395A (en) * 1994-06-07 1996-01-04 Sri International Novel compounds useful in modulating gene expression of retinoid responsive genes and/or having anti-ap-1 activity
US5770378A (en) * 1994-12-30 1998-06-23 Ligand Pharmaceuticals, Inc. Tricyclic retinoids, methods for their production and use
US5770382A (en) * 1994-12-30 1998-06-23 Ligand Pharmaceuticals, Inc. Tricyclic retinoids, methods for their production and use
EP0800504B1 (de) * 1994-12-30 1999-12-01 Ligand Pharmaceuticals Incorporated Trizyclische retinoidverbindungen verfahren zu ihrer herstellung und verwendung
US5770383A (en) * 1994-12-30 1998-06-23 Ligand Pharmaceuticals, Inc. Tricyclic retinoids, methods for their production and use
US5559248A (en) * 1995-04-05 1996-09-24 Bristol-Myers Squibb Co. Retinoid-like heterocycles
FR2733684B1 (fr) * 1995-05-03 1997-05-30 Cird Galderma Utilisation de retinoides dans une composition cosmetique ou pour la fabrication d'une composition pharmaceutique
KR100625255B1 (ko) 1995-10-06 2008-01-30 리간드 파마슈티칼스 인코포레이티드 다이머-선택적rxr변조물질및그의사용방법
FR2755011B1 (fr) * 1996-10-31 1998-11-20 Cird Galderma Utilisation des inhibiteurs de l'activite de l'acide retinoique pour traiter les peaux sensibles et/ou les dommages aigus induits par les rayonnements u.v.
FR2757852B1 (fr) 1996-12-31 1999-02-19 Cird Galderma Composes stilbeniques a groupement adamantyl, compositions les contenant et utilisations
AU6229698A (en) * 1997-02-21 1998-09-09 Takeda Chemical Industries Ltd. Fused ring compounds, process for producing the same and use thereof
EP1093362A1 (de) * 1998-06-12 2001-04-25 Ligand Pharmaceuticals Incorporated Verwendung von rxr modulatoren zur behandlung von anti-östrogen-resistent brustkrebs
JP2003508397A (ja) 1999-08-27 2003-03-04 リガンド・ファーマシューティカルズ・インコーポレイテッド アンドロゲンレセプターモジュレーターとしての８−置換−６−トリフルオロメチル−９−ピリド［３，２−ｇ］キノリン化合物
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
CZ2002711A3 (cs) 1999-08-27 2003-11-12 Ligand Pharmaceuticals Incorporated Modulátory androgenních receptorů, způsoby jejich výroby a způsoby jejich použití
EP1216221A2 (de) 1999-09-14 2002-06-26 Ligand Pharmaceuticals Incorporated Rxr modulatoren mit verbessertem pharmakologischem profil
WO2001024775A1 (en) * 1999-10-01 2001-04-12 Essentia Biosystems, Inc. Gel-forming compositions
EP1429765A2 (de) 2001-09-14 2004-06-23 Methylgene, Inc. Histone deacetylase-hemmer
US9050310B2 (en) * 2004-06-25 2015-06-09 Minas Theodore Coroneo Treatment of ocular lesions
US20060204474A1 (en) * 2005-02-25 2006-09-14 Coroneo Minas T Treatment of epithelial layer lesions
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
FR2931661B1 (fr) 2008-05-30 2010-07-30 Galderma Res & Dev Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide.
AU2011343518B2 (en) 2010-12-16 2016-11-10 Nivalis Therapeutics, Inc. Novel substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
FR2974299A1 (fr) * 2011-04-21 2012-10-26 Agronomique Inst Nat Rech Compositions antivirales dirigees contre la nucleoproteine des virus influenza
CA2883788A1 (en) * 2012-09-04 2014-03-13 Lauren Sciences Llc Bolaamphiphilic compounds, compositions and uses thereof
WO2017053778A1 (en) 2015-09-25 2017-03-30 Fuchs Helen Burgwyn Antibacterial and antifungal compounds
US11045441B2 (en) 2015-10-13 2021-06-29 Wisconsin Alumni Research Foundation Use of retinoic acid and analogs thereof to treat central neural apneas
US11278025B2 (en) 2017-05-17 2022-03-22 The General Hospital Corporation Antibiotic compounds
WO2019018185A1 (en) 2017-07-15 2019-01-24 Arisan Therapeutics Inc. ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS

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US2153135A (en) * 1937-11-26 1939-04-04 Eastman Kodak Co Yarn treating processes and compositions therefor
US2532515A (en) * 1947-01-29 1950-12-05 Universal Oil Prod Co Catalytic condensation of furans with compounds capable of yielding hydrocarbon radicals
US3940502A (en) * 1972-04-13 1976-02-24 Firmenich & Cie Flavoring agent
US4578522A (en) * 1983-08-31 1986-03-25 Eaddy Iii John F Biaryl aldehyde

Also Published As

Publication number Publication date
FI87454C (fi) 1993-01-11
IL79506A0 (en) 1986-10-31
JP2614606B2 (ja) 1997-05-28
PT83056A (en) 1986-08-01
US5602104A (en) 1997-02-11
DE3685528D1 (de) 1992-07-09
US5434180A (en) 1995-07-18
AU596109B2 (en) 1990-04-26
US5124473A (en) 1992-06-23
EP0210929A2 (de) 1987-02-04
CA1269371A (fr) 1990-05-22
DK170769B1 (da) 1996-01-15
GR861950B (en) 1986-11-25
PT83056B (pt) 1988-07-01
DK65591A (da) 1991-04-11
CA1297127C (fr) 1992-03-10
EP0210929B1 (de) 1992-06-03
DK65591D0 (da) 1991-04-11
NO862966D0 (no) 1986-07-23
NO166936C (no) 1991-09-18
NZ216963A (en) 1989-07-27
DE210929T1 (de) 1988-12-15
JPS6236337A (ja) 1987-02-17
ES2002727A6 (es) 1988-10-01
ATE76864T1 (de) 1992-06-15
DK352486A (da) 1987-01-26
AU6049986A (en) 1987-01-29
CA1271422A (fr) 1990-07-10
NO166936B (no) 1991-06-10
DK352486D0 (da) 1986-07-24
ZA865572B (en) 1987-03-25
FI87454B (fi) 1992-09-30
FI863036A0 (fi) 1986-07-24
EP0210929A3 (en) 1988-10-12
DE3685528T2 (de) 1992-12-24
US5686586A (en) 1997-11-11
NO862966L (no) 1987-01-26
FI863036A (fi) 1987-01-26

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