DE3685528T2 - Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen. - Google Patents
Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen.Info
- Publication number
- DE3685528T2 DE3685528T2 DE8686401671T DE3685528T DE3685528T2 DE 3685528 T2 DE3685528 T2 DE 3685528T2 DE 8686401671 T DE8686401671 T DE 8686401671T DE 3685528 T DE3685528 T DE 3685528T DE 3685528 T2 DE3685528 T2 DE 3685528T2
- Authority
- DE
- Germany
- Prior art keywords
- radical
- carbon atoms
- representing
- optionally substituted
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/49—Polycyclic acids containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU86022A LU86022A1 (fr) | 1985-07-25 | 1985-07-25 | Derives aromatiques polycyliques,leur procede de preparation et leur application dans les domaines pharmaceutique et cosmetique |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3685528D1 DE3685528D1 (de) | 1992-07-09 |
DE3685528T2 true DE3685528T2 (de) | 1992-12-24 |
Family
ID=19730521
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198686401671T Pending DE210929T1 (de) | 1985-07-25 | 1986-07-25 | Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen. |
DE8686401671T Expired - Fee Related DE3685528T2 (de) | 1985-07-25 | 1986-07-25 | Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE198686401671T Pending DE210929T1 (de) | 1985-07-25 | 1986-07-25 | Aromatische polycyclische derivate, verfahren zu ihrer herstellung und ihre verwendung in pharmazeutischen und kosmetischen zubereitungen. |
Country Status (16)
Country | Link |
---|---|
US (4) | US5124473A (de) |
EP (1) | EP0210929B1 (de) |
JP (1) | JP2614606B2 (de) |
AT (1) | ATE76864T1 (de) |
CA (3) | CA1269371A (de) |
DE (2) | DE210929T1 (de) |
DK (2) | DK170769B1 (de) |
ES (1) | ES2002727A6 (de) |
FI (1) | FI87454C (de) |
GR (1) | GR861950B (de) |
IL (1) | IL79506A0 (de) |
LU (1) | LU86022A1 (de) |
NO (1) | NO166936C (de) |
NZ (1) | NZ216963A (de) |
PT (1) | PT83056B (de) |
ZA (1) | ZA865572B (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU599135B2 (en) * | 1986-07-16 | 1990-07-12 | Albert M. Kligman | Methods for treatment of sundamaged human skin with retinoids |
LU87040A1 (fr) * | 1987-11-04 | 1989-06-14 | Oreal | Esters aromatiques polycycliques d'antibiotiques macrolidiques et lincosamidiques,leur procede de preparation et compositions pharmaceutiques et cosmetiques les contenant |
FR2635683B1 (fr) * | 1988-09-01 | 1990-11-09 | Cird | Nouveau compose marque au tritium, sa preparation et son application notamment dans la determination de l'affinite des retinoides pour leurs recepteurs nucleaires et leur proteine de liaison cytosolique |
US5146025A (en) * | 1989-02-28 | 1992-09-08 | Mitsubishi Gas Chemical Company, Inc. | Naphthalene compounds |
US5324840A (en) * | 1992-06-11 | 1994-06-28 | Allergan, Inc. | Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects |
US5466861A (en) * | 1992-11-25 | 1995-11-14 | Sri International | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors |
US5455265A (en) * | 1993-02-11 | 1995-10-03 | Allergan, Inc. | Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors |
US6172115B1 (en) | 1993-02-11 | 2001-01-09 | Allergan Sales, Inc. | Method for preventing onset of restenosis after angioplasty employing an RXR-specific retinoid |
US5399586A (en) * | 1993-03-11 | 1995-03-21 | Allergan, Inc. | Treatment of mammals afflicted with tumors with compounds having RXR retinoid receptor agonist activity |
FR2713640B1 (fr) * | 1993-12-15 | 1996-01-05 | Cird Galderma | Nouveaux composés aromatiques polycycliques, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
AU2823395A (en) * | 1994-06-07 | 1996-01-04 | Sri International | Novel compounds useful in modulating gene expression of retinoid responsive genes and/or having anti-ap-1 activity |
US5770378A (en) * | 1994-12-30 | 1998-06-23 | Ligand Pharmaceuticals, Inc. | Tricyclic retinoids, methods for their production and use |
US5770383A (en) * | 1994-12-30 | 1998-06-23 | Ligand Pharmaceuticals, Inc. | Tricyclic retinoids, methods for their production and use |
DE69513689T2 (de) * | 1994-12-30 | 2000-05-25 | Ligand Pharm Inc | Trizyclische retinoidverbindungen verfahren zu ihrer herstellung und verwendung |
US5770382A (en) * | 1994-12-30 | 1998-06-23 | Ligand Pharmaceuticals, Inc. | Tricyclic retinoids, methods for their production and use |
US5559248A (en) * | 1995-04-05 | 1996-09-24 | Bristol-Myers Squibb Co. | Retinoid-like heterocycles |
FR2733684B1 (fr) | 1995-05-03 | 1997-05-30 | Cird Galderma | Utilisation de retinoides dans une composition cosmetique ou pour la fabrication d'une composition pharmaceutique |
PT873295E (pt) | 1995-10-06 | 2003-08-29 | Ligand Pharm Inc | Moduladores de rxr selectivos para dimeros para a sua utilizacao |
FR2755011B1 (fr) * | 1996-10-31 | 1998-11-20 | Cird Galderma | Utilisation des inhibiteurs de l'activite de l'acide retinoique pour traiter les peaux sensibles et/ou les dommages aigus induits par les rayonnements u.v. |
FR2757852B1 (fr) | 1996-12-31 | 1999-02-19 | Cird Galderma | Composes stilbeniques a groupement adamantyl, compositions les contenant et utilisations |
US6420375B1 (en) * | 1997-02-21 | 2002-07-16 | Takeda Chemical Industries, Ltd. | Fused ring compounds, process for producing the same and use thereof |
WO1999063980A1 (en) * | 1998-06-12 | 1999-12-16 | Ligand Pharmaceuticals Inc. | Treatment of anti-estrogen resistant breast cancer using rxr modulators |
US6566372B1 (en) | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
WO2001016139A1 (en) | 1999-08-27 | 2001-03-08 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
US6667313B1 (en) | 1999-08-27 | 2003-12-23 | Ligand Pharmaceuticals Inc. | 8-substituted-6-triflouromethyl-9-pyrido [3,2-G] quinoline compounds as androgen receptor modulators |
AU7586600A (en) * | 1999-09-14 | 2001-04-17 | Ligand Pharmaceuticals Incorporated | Rxr modulators with improved pharmacologic profile |
WO2001024775A1 (en) * | 1999-10-01 | 2001-04-12 | Essentia Biosystems, Inc. | Gel-forming compositions |
KR20040048411A (ko) | 2001-09-14 | 2004-06-09 | 메틸진, 인크. | 히스톤 데아세틸라아제의 억제제 |
US9050310B2 (en) * | 2004-06-25 | 2015-06-09 | Minas Theodore Coroneo | Treatment of ocular lesions |
US20060204474A1 (en) * | 2005-02-25 | 2006-09-14 | Coroneo Minas T | Treatment of epithelial layer lesions |
FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
FR2910320B1 (fr) | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
FR2931661B1 (fr) | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide. |
JP5990187B2 (ja) | 2010-12-16 | 2016-09-07 | ニヴァリス・セラピューティクス・インコーポレーテッド | S−ニトロソグルタチオン還元酵素阻害薬としての新規な置換二環芳香族化合物 |
FR2974299A1 (fr) * | 2011-04-21 | 2012-10-26 | Agronomique Inst Nat Rech | Compositions antivirales dirigees contre la nucleoproteine des virus influenza |
WO2014039503A1 (en) * | 2012-09-04 | 2014-03-13 | Lauren Sciences Llc | Bolaamphiphilic compounds, compositions and uses thereof |
WO2017053778A1 (en) | 2015-09-25 | 2017-03-30 | Fuchs Helen Burgwyn | Antibacterial and antifungal compounds |
US11045441B2 (en) | 2015-10-13 | 2021-06-29 | Wisconsin Alumni Research Foundation | Use of retinoic acid and analogs thereof to treat central neural apneas |
US11278025B2 (en) | 2017-05-17 | 2022-03-22 | The General Hospital Corporation | Antibiotic compounds |
WO2019018185A1 (en) | 2017-07-15 | 2019-01-24 | Arisan Therapeutics Inc. | ENANTIOMERICALLY PURE ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTIONS |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2153135A (en) * | 1937-11-26 | 1939-04-04 | Eastman Kodak Co | Yarn treating processes and compositions therefor |
US2532515A (en) * | 1947-01-29 | 1950-12-05 | Universal Oil Prod Co | Catalytic condensation of furans with compounds capable of yielding hydrocarbon radicals |
US3940502A (en) * | 1972-04-13 | 1976-02-24 | Firmenich & Cie | Flavoring agent |
US4578522A (en) * | 1983-08-31 | 1986-03-25 | Eaddy Iii John F | Biaryl aldehyde |
-
1985
- 1985-07-25 LU LU86022A patent/LU86022A1/fr unknown
-
1986
- 1986-07-23 NO NO862966A patent/NO166936C/no unknown
- 1986-07-24 DK DK352486A patent/DK170769B1/da not_active IP Right Cessation
- 1986-07-24 PT PT83056A patent/PT83056B/pt unknown
- 1986-07-24 IL IL79506A patent/IL79506A0/xx unknown
- 1986-07-24 NZ NZ216963A patent/NZ216963A/xx unknown
- 1986-07-24 JP JP61175471A patent/JP2614606B2/ja not_active Expired - Fee Related
- 1986-07-24 GR GR861950A patent/GR861950B/el unknown
- 1986-07-24 FI FI863036A patent/FI87454C/fi not_active IP Right Cessation
- 1986-07-24 CA CA000514630A patent/CA1269371A/fr not_active Expired - Lifetime
- 1986-07-24 CA CA000514631A patent/CA1271422A/fr not_active Expired - Lifetime
- 1986-07-24 ES ES8601337A patent/ES2002727A6/es not_active Expired
- 1986-07-25 DE DE198686401671T patent/DE210929T1/de active Pending
- 1986-07-25 EP EP86401671A patent/EP0210929B1/de not_active Expired - Lifetime
- 1986-07-25 AT AT86401671T patent/ATE76864T1/de not_active IP Right Cessation
- 1986-07-25 ZA ZA865572A patent/ZA865572B/xx unknown
- 1986-07-25 DE DE8686401671T patent/DE3685528T2/de not_active Expired - Fee Related
-
1990
- 1990-01-22 CA CA000615615A patent/CA1297127C/fr not_active Expired - Lifetime
- 1990-09-12 US US07/580,916 patent/US5124473A/en not_active Expired - Lifetime
-
1991
- 1991-04-11 DK DK91655A patent/DK65591D0/da not_active Application Discontinuation
-
1992
- 1992-03-27 US US07/859,046 patent/US5434180A/en not_active Expired - Fee Related
-
1995
- 1995-04-13 US US08/421,235 patent/US5602104A/en not_active Expired - Fee Related
-
1996
- 1996-10-04 US US08/725,496 patent/US5686586A/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |