LU84851A1 - Derives de l'oxazolidinone-2 n-arylee optiquement actifs,inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation - Google Patents

Derives de l'oxazolidinone-2 n-arylee optiquement actifs,inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation Download PDF

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Publication number
LU84851A1
LU84851A1 LU84851A LU84851A LU84851A1 LU 84851 A1 LU84851 A1 LU 84851A1 LU 84851 A LU84851 A LU 84851A LU 84851 A LU84851 A LU 84851A LU 84851 A1 LU84851 A1 LU 84851A1
Authority
LU
Luxembourg
Prior art keywords
formula
compound
derivative
preparation
derivatives
Prior art date
Application number
LU84851A
Other languages
English (en)
French (fr)
Inventor
Philippe Dostert
Michel Langlois
Margherita Strolin-Benedetti
Patrick Guerret
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of LU84851A1 publication Critical patent/LU84851A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU84851A 1982-06-08 1983-06-07 Derives de l'oxazolidinone-2 n-arylee optiquement actifs,inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation LU84851A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8209972 1982-06-08
FR8209972A FR2528046B1 (fr) 1982-06-08 1982-06-08 Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Publications (1)

Publication Number Publication Date
LU84851A1 true LU84851A1 (fr) 1985-03-29

Family

ID=9274766

Family Applications (1)

Application Number Title Priority Date Filing Date
LU84851A LU84851A1 (fr) 1982-06-08 1983-06-07 Derives de l'oxazolidinone-2 n-arylee optiquement actifs,inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Country Status (13)

Country Link
US (1) US4598084A (sv)
JP (1) JPS5980668A (sv)
AU (1) AU1546283A (sv)
BE (1) BE896972A (sv)
CH (3) CH657362A5 (sv)
DE (1) DE3320394A1 (sv)
FR (1) FR2528046B1 (sv)
GB (3) GB2121413B (sv)
IT (1) IT1164269B (sv)
LU (1) LU84851A1 (sv)
NL (1) NL8302013A (sv)
SE (2) SE8303136L (sv)
ZA (1) ZA834119B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241893A (ja) * 1984-05-15 1985-11-30 Kanegafuchi Chem Ind Co Ltd 光学活性（ｓ）―オキサゾリジノン誘導体の製造方法
DE3525648A1 (de) * 1985-07-18 1987-01-29 Bokel Heinz Hermann Dr 1-oxa-2-oxo-2-r-3-aza-5-z-cyclopentanderivate
FR2609029B1 (fr) * 1986-12-30 1989-12-08 Delalande Sa Derives 5-aminoethyles de l'oxazolidinone-2, leur procede de preparation et leur application en therapeutique
AU7778087A (en) * 1986-09-03 1988-04-14 Delalande S.A. 5-aminoethyloxazolidin-2-one derivatives
FR2603279B1 (fr) * 1986-09-03 1988-12-16 Rech Ind Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique
FR2626877B1 (fr) * 1988-02-05 1991-04-05 Delalande Sa Ethers alkyliques ou benzyliques du phenol, leurs procedes de preparation et leur application en therapeutique
US5196543A (en) * 1989-10-17 1993-03-23 Delalande S.A. 3-aryloxazolidinone derivatives, process for their preparation and their use in therapy
US5235063A (en) * 1989-10-17 1993-08-10 Delalande S.A. Process of preparing by condensation certain
JPH06508836A (ja) * 1991-06-26 1994-10-06 セプラコア，インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する嘔吐、吐き気および他の障害の治療のための方法および組成物
AU3147593A (en) * 1991-11-26 1993-06-28 Sepracor, Inc. Methods and compositions for treating hypertension, angina and other disorders using optically pure (-) amlodipine
CA2371822A1 (en) 1999-03-01 2000-09-08 Sepracor Inc. Methods for treating apnea and apnea disorders using optically pure r(+)ondansetron

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
FR2428032A1 (fr) * 1978-06-09 1980-01-04 Delalande Sa Nouvelles oxazolidimones, oxazolidinethiones et pyrrolidinones, leur procede de preparation et leur application en therapeutique
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones

Also Published As

Publication number Publication date
BE896972A (fr) 1983-12-06
US4598084A (en) 1986-07-01
GB2157693A (en) 1985-10-30
GB8512020D0 (en) 1985-06-19
FR2528046A1 (fr) 1983-12-09
GB8315433D0 (en) 1983-07-13
SE8802281D0 (sv) 1988-06-17
CH661500A5 (fr) 1987-07-31
NL8302013A (nl) 1984-01-02
GB8512019D0 (en) 1985-06-19
GB2157692A (en) 1985-10-30
GB2121413A (en) 1983-12-21
IT1164269B (it) 1987-04-08
SE8303136L (sv) 1983-12-09
CH661507A5 (fr) 1987-07-31
JPS5980668A (ja) 1984-05-10
IT8321497A0 (it) 1983-06-07
GB2157693B (en) 1986-05-08
GB2121413B (en) 1986-05-08
ZA834119B (en) 1984-03-28
SE8802281L (sv) 1988-06-17
FR2528046B1 (fr) 1985-06-21
AU1546283A (en) 1983-12-15
GB2157692B (en) 1986-05-08
SE8303136D0 (sv) 1983-06-03
DE3320394A1 (de) 1983-12-08
CH657362A5 (fr) 1986-08-29

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