IT1164269B - Derivati dell'ossazolidinone-2n-arilato otticamente attivi, inibitori specifici e reversibili della monoammino ossidasi di tipo b e loro procedimento di preparazione - Google Patents

Derivati dell'ossazolidinone-2n-arilato otticamente attivi, inibitori specifici e reversibili della monoammino ossidasi di tipo b e loro procedimento di preparazione

Info

Publication number
IT1164269B
IT1164269B IT21497/83A IT2149783A IT1164269B IT 1164269 B IT1164269 B IT 1164269B IT 21497/83 A IT21497/83 A IT 21497/83A IT 2149783 A IT2149783 A IT 2149783A IT 1164269 B IT1164269 B IT 1164269B
Authority
IT
Italy
Prior art keywords
oxyzolidinone
arylate
derivatives
specific
type
Prior art date
Application number
IT21497/83A
Other languages
English (en)
Other versions
IT8321497A0 (it
Inventor
Benedetti Margherita Strolin
Patrick Guerret
Michel Langlois
Philippe Dostert
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of IT8321497A0 publication Critical patent/IT8321497A0/it
Application granted granted Critical
Publication of IT1164269B publication Critical patent/IT1164269B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
IT21497/83A 1982-06-08 1983-06-07 Derivati dell'ossazolidinone-2n-arilato otticamente attivi, inibitori specifici e reversibili della monoammino ossidasi di tipo b e loro procedimento di preparazione IT1164269B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8209972A FR2528046B1 (fr) 1982-06-08 1982-06-08 Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation

Publications (2)

Publication Number Publication Date
IT8321497A0 IT8321497A0 (it) 1983-06-07
IT1164269B true IT1164269B (it) 1987-04-08

Family

ID=9274766

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21497/83A IT1164269B (it) 1982-06-08 1983-06-07 Derivati dell'ossazolidinone-2n-arilato otticamente attivi, inibitori specifici e reversibili della monoammino ossidasi di tipo b e loro procedimento di preparazione

Country Status (13)

Country Link
US (1) US4598084A (it)
JP (1) JPS5980668A (it)
AU (1) AU1546283A (it)
BE (1) BE896972A (it)
CH (3) CH661507A5 (it)
DE (1) DE3320394A1 (it)
FR (1) FR2528046B1 (it)
GB (3) GB2121413B (it)
IT (1) IT1164269B (it)
LU (1) LU84851A1 (it)
NL (1) NL8302013A (it)
SE (2) SE8303136L (it)
ZA (1) ZA834119B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241893A (ja) * 1984-05-15 1985-11-30 Kanegafuchi Chem Ind Co Ltd 光学活性（ｓ）―オキサゾリジノン誘導体の製造方法
DE3525648A1 (de) * 1985-07-18 1987-01-29 Bokel Heinz Hermann Dr 1-oxa-2-oxo-2-r-3-aza-5-z-cyclopentanderivate
FR2609029B1 (fr) * 1986-12-30 1989-12-08 Delalande Sa Derives 5-aminoethyles de l'oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2603279B1 (fr) * 1986-09-03 1988-12-16 Rech Ind Benzyloxy-phenyl-oxazolidinones, procede de preparation et utilisation en therapeutique
CA1302422C (en) * 1986-09-03 1992-06-02 Margherita Strolin-Benedetti 5-aminoethyloxazolidin-2-one derivatives, process for the preparation thereofand their therapeutic use
FR2626877B1 (fr) * 1988-02-05 1991-04-05 Delalande Sa Ethers alkyliques ou benzyliques du phenol, leurs procedes de preparation et leur application en therapeutique
US5196543A (en) * 1989-10-17 1993-03-23 Delalande S.A. 3-aryloxazolidinone derivatives, process for their preparation and their use in therapy
US5235063A (en) * 1989-10-17 1993-08-10 Delalande S.A. Process of preparing by condensation certain
JPH06508836A (ja) * 1991-06-26 1994-10-06 セプラコア，インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する嘔吐、吐き気および他の障害の治療のための方法および組成物
JPH07501547A (ja) * 1991-11-26 1995-02-16 セプラコア，インコーポレーテッド 光学的に純粋な（−）アムロジピンを用いる，高血圧，狭心症および他の疾患を治療するための方法および組成物
JP2002538102A (ja) 1999-03-01 2002-11-12 セプラコア インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する無呼吸および無呼吸障害の治療方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2356422A1 (fr) * 1976-03-01 1978-01-27 Delalande Sa Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR2380780A2 (fr) * 1977-02-22 1978-09-15 Delalande Sa Application en therapeutique des hydroxymethyl-5 oxazolidinones-2, notamment comme antidepresseurs
LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
FR2428032A1 (fr) * 1978-06-09 1980-01-04 Delalande Sa Nouvelles oxazolidimones, oxazolidinethiones et pyrrolidinones, leur procede de preparation et leur application en therapeutique
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones

Also Published As

Publication number Publication date
US4598084A (en) 1986-07-01
LU84851A1 (fr) 1985-03-29
GB8512020D0 (en) 1985-06-19
DE3320394A1 (de) 1983-12-08
CH661507A5 (fr) 1987-07-31
IT8321497A0 (it) 1983-06-07
BE896972A (fr) 1983-12-06
SE8802281L (sv) 1988-06-17
GB2157692B (en) 1986-05-08
ZA834119B (en) 1984-03-28
GB2157693B (en) 1986-05-08
GB2157693A (en) 1985-10-30
FR2528046A1 (fr) 1983-12-09
GB8315433D0 (en) 1983-07-13
FR2528046B1 (fr) 1985-06-21
JPS5980668A (ja) 1984-05-10
NL8302013A (nl) 1984-01-02
GB2157692A (en) 1985-10-30
CH657362A5 (fr) 1986-08-29
AU1546283A (en) 1983-12-15
GB8512019D0 (en) 1985-06-19
CH661500A5 (fr) 1987-07-31
GB2121413B (en) 1986-05-08
SE8802281D0 (sv) 1988-06-17
GB2121413A (en) 1983-12-21
SE8303136L (sv) 1983-12-09
SE8303136D0 (sv) 1983-06-03

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